Lorazepam vs. diazepam: Bambanci, kamanceceniya, kuma wanene yafi muku alheri
Magunguna vs. AbokiBayanin magunguna & manyan bambance-bambance | Yanayin da aka bi | Inganci | Inshorar inshora da kwatancen farashi | Sakamakon sakamako | Hadin magunguna | Gargadi | Tambayoyi
Lorazepam da diazepam magunguna ne na gama gari waɗanda ke aiki don magance rikicewar tashin hankali, tsakanin sauran yanayin lafiyar hankali. Dukansu kwayoyi an lasafta su azaman benzodiazepines. Suna aiki ta haɓaka aikin GABA, ko gamma-aminobutyric acid, a cikin kwakwalwa. Neurotransmitter GABA wani sinadari ne mai hana mutum toshe wasu siginar jijiyoyi, da haɓaka yanayi, da inganta natsuwa.
Dukansu lorazepam da diazepam duk kwayoyi ne na Jadawalin IV, a cewar Hukumar Kula da Tilasta Amfani da Miyagun Kwayoyi (DEA). Wannan yana nufin cewa waɗannan magungunan, kamar sauran benzodiazepines, suna da haɗarin dogaro da zagi. Sabili da haka, ya kamata a yi amfani da su azaman ɗan gajeren lokaci kawai ƙarƙashin kulawar mai ba da kiwon lafiya.
Karanta don koyo game da sauran bambance-bambance tsakanin lorazepam da diazepam.
Menene manyan bambance-bambance tsakanin lorazepam da diazepam?
Babban bambanci tsakanin lorazepam da diazepam shine cewa diazepam ya zauna cikin jiki fiye da lorazepam. Lorazepam, wanda shine ainihin sunan Ativan, yana da rabin rai har zuwa 18 hours . A gefe guda, diazepam, wanda shine asalin sunan Valium, yana da rabin rai har zuwa 48 hours . Sabili da haka, ana ɗaukar lorazepam a matsayin mai tsaka-tsakin aiki benzodiazepine, kuma ana ɗaukar diazepam a matsayin mai benzodiazepine mai dogon lokaci.
Lorazepam da diazepam suma suna narkewa, ko sarrafa su, cikin jiki daban. Lorazepam yana cike cikin hanta ta hanyar aiwatarwa da aka sani da glucuronidation . Diazepam yana cike cikin hanta ta hanyar enzymes na cytochrome. A sakamakon haka, diazepam yana da damar yin ma'amala da wasu magunguna fiye da lorazepam.
Ana samun Lorazepam a cikin allunan baka na yau da kullun tare da ƙarfin 0.5 MG, 1 MG, da 2 MG. Hakanan yana zuwa azaman maganin baka da kuma maganin allura. Ana samun Ativan a cikin ƙananan kwayoyin baka tare da ƙarfin 2 MG, 5 MG, da 10 MG. Kuma ana iya gudanar da Ativan azaman maganin baka, maganin allura, da gel na dubura.
| Babban bambance-bambance tsakanin lorazepam da diazepam | ||
|---|---|---|
| Lorazepam | Diazepam | |
| Ajin magani | Benzodiazepine | Benzodiazepine |
| Alamar alama / ta kowa | Nau'i da nau'ikan sigar akwai | Nau'i da nau'ikan sigar akwai |
| Menene sunan alamar? | Ativan | Valium |
| Wani nau'i (s) ne miyagun ƙwayoyi ya shigo? | Rubutun baka Maganin baka Magani ga allura | Rubutun baka Maganin baka Magani ga allura Gel ɗin ƙarfe |
| Menene daidaitaccen sashi? | Don damuwa: Farawa: 2 zuwa 3 MG ta bakin 2 zuwa sau 3 kowace rana Tsarin kulawa: 2 zuwa 6 MG 2 zuwa sau 3 kowace rana | Don damuwa: 2 zuwa 10 MG ta baki 2 zuwa sau 4 a kowace rana |
| Yaya tsawon maganin al'ada? | Ba zai fi watanni 4 ba | Ba zai fi watanni 4 ba |
| Wanene yawanci yake amfani da magani? | Manya da yara ‘yan shekara 12 zuwa sama | Manya, yara, da jarirai wata 6 zuwa sama |
Yanayin da lorazepam vs. diazepam yayi maganin sa
Lorazepam da diazepam suna aiki azaman tashin hankali don rage alamun rashin damuwa, kamar damuwa mai girma da wahalar tunani a fili. Lorazepam da diazepam duk an yarda da FDA don magance damuwa da damuwa, irin su rikicewar tsoro da kai hare-hare.
Kamar sauran benzodiazepines, ana iya amfani da lorazepam da diazepam don magance rikicewar kamuwa, ko farfadiya. Hakanan za'a iya amfani dasu azaman premedication kafin ayi musu tiyata don larurar kwantar da hankali.
Diazepam kuma an yarda da FDA don magance cututtukan cire barasa da cututtukan tsoka. Bugu da ƙari don magance damuwa, an kuma yarda da lorazepam don magance rashin barci wanda damuwa ya haifar. Sauran amfani-lakabin ana iya samun su a cikin tebur ɗin da ke ƙasa.
| Yanayi | Lorazepam | Diazepam |
| Rashin damuwa | Ee | Ee |
| Rashin barci wanda ke haifar da damuwa | Ee | Kashe-lakabi |
| Ciwon shan barasa | Kashe-lakabi | Ee |
| Magungunan tsoka | Kashe-lakabi | Ee |
| Rashin lafiya | Ee | Ee |
| Yanayin farfadiya | Ee | Ee |
| Sation ko premedication kafin tiyata | Ee | Ee |
Shin lorazepam vs. diazepam yafi tasiri?
Idan aka kwatanta da placebo, ko babu magani, duka lorazepam da diazepam suna da tasiri don magance damuwa. Benzodiazepine mafi inganci zai dogara ne akan yanayin da ake bi da shi, ana shan wasu magunguna, da duk wani magani da aka gwada a baya.
Bazuwar, gwajin gwaji na asibiti sun nuna yawancin cewa lorazepam da diazepam suna kama da tasiri don magance damuwa. Makafi daya gwajin asibiti gwada lorazepam da diazepam a cikin 134 marasa lafiya masu damuwa sama da makonni huɗu sun gano cewa duka kwayoyi sun fi placebo tasiri. Koyaya, an gano lorazepam ya zama mafi tasiri ga marasa lafiya waɗanda ke da mummunan cututtuka a farko. Sedation an bayar da rahoton ya zama mafi mahimmancin sakamako a cikin ƙungiyar da ke ɗaukar lorazepam.
A cikin wani cibiyar sadarwa meta-bincike , midazolam, lorazepam, da diazepam an gwama su don magance matsayin epilepticus, matsanancin kamuwa da cuta, a cikin yara. Bayanai da aka tattara daga gwaji daban-daban na asibiti guda 16 sun gano cewa midazolam da lorazepam sun fi diazepam tasiri.
Wannan kwatancen shine don dalilai na gama gari. Nemi shawarwarin likita daga likita ko mai bada sabis kafin amfani da benzodiazepine. Mai ba ku kiwon lafiya zai gudanar da cikakken binciken likita don sanin tsananin yanayin ku da kuma yin watsi da wasu halaye na lafiyar kwakwalwa.
Verageaukar hoto da kwatancen farashi na lorazepam vs. diazepam
Gabaɗaya tsarin Medicare da tsare-tsaren inshora suna rufe tsarin lorazepam. Ba tare da inshora ba, farashin tsabar kuɗi na iya zama $ 25 don 30, Allunan MG 0.5. SingleCare lorazepam coupon na iya kawo kuɗin kusan $ 9.
Kamar sauran magungunan ƙwayoyi, diazepam galibi ana rufe shi ta Medicare da tsare-tsaren inshora. Matsakaicin farashin tsabar kudi na diazepam shine kusan $ 24 don 30, Allunan MG 0.5. Idan aka kwatanta da lorazepam, diazepam na iya zama mai ɗan rahusa dangane da kantin ku. Amfani da coupon diazepam na SingleCare na iya rage farashin zuwa $ 7 a shagunan sayar da magani.
| Lorazepam | Diazepam | |
| Yawanci inshora ya rufe? | Ee | Ee |
| Yawanci an rufe shi ta Medicare Part D? | Ee | Ee |
| Daidaitaccen sashi | 2 zuwa 6 MG 2 zuwa sau 3 a kowace rana | 2 zuwa 10 MG ta baki 2 zuwa sau 4 a kowace rana |
| Hanyar biyan kuɗaɗe na Medicare | $ 0– $ 25 | $ 0– $ 12 |
| SingleCare kudin | $ 8 + | $ 6 + |
Illolin yau da kullun na lorazepam vs. diazepam
Lorazepam da diazepam, kamar sauran benzodiazepines, da farko suna haifar da sakamako mai illa a cikin tsarin juyayi na tsakiya (CNS). Mafi na kowa sakamako masu illa na lorazepam , ko Ativan, sune kwantar da hankali, jiri, rauni, da rashin kwanciyar hankali, ko rashin daidaito. Abubuwan da suka fi dacewa na diazepam, ko Valium, sune bacci, gajiya, raunin tsoka, da rashin daidaituwa.
Sauran sakamako masu illa na iya haɗawa da matsalolin ƙwaƙwalwa. Faruwar sakamako masu illa yawanci yana dogara ne akan sashin shan magani da aka sha. An bayar da rahoton ƙarin illa masu haɗari tare da babban allurai na benzodiazepines. Babban sakamako mai illa, gami da ɓacin rai na numfashi, ko zurfin numfashi, na iya nuna gaggawa ta likita.
| Lorazepam | Diazepam | |||
| Sakamakon sakamako | Ana amfani? | Mitar lokaci | Ana amfani? | Mitar lokaci |
| Natsuwa | Ee | 16% | Ee | * |
| Bacci | Ee | * | Ee | * |
| Gajiya | Ee | * | Ee | * |
| Dizziness | Ee | 7% | Ee | * |
| Rashin ƙarfi | Ee | 4% | Ee | * |
| Tsarin aiki mara kyau | Ee | 3% | Ee | * |
| Matsalar ƙwaƙwalwa | Ee | * | Ee | * |
* ba'a ruwaito ba
Mitar ba ta dogara da bayanai daga gwajin kai-da-kai. Wannan na iya zama ba cikakken jerin illolin da zasu iya faruwa ba. Da fatan za a koma zuwa likitanku ko mai ba da sabis na kiwon lafiya don ƙarin koyo.
Source: DailyMed ( Lorazepam ,, DailyMed ( Diazepam )
Magungunan ƙwayoyi na lorazepam vs. diazepam
Lorazepam da diazepam da farko suna hulɗa tare da wasu magunguna waɗanda ke shafar tsarin juyayi na tsakiya (CNS). Shan waɗannan benzodiazepines tare da ƙwayoyi kamar opioids, barbiturates, antipsychotics, antidepressants, da anticonvulsants na iya haifar da ƙarin tasirin CNS-depressant, kamar su dizziness, rikicewa, da bacci. Maganin antigout probenecid na iya shafar metabolism na benzodiazepines kuma yana haifar da ƙarin sakamako masu illa.
Yin amfani da theophylline ko aminophylline na iya magance tasirin kuzari na benzodiazepines. Faɗa wa likitanka idan ka sha ɗayan waɗannan ƙwayoyi kafin fara benzodiazepine.
Diazepam ana sarrafa shi ta wasu enzymes P450 yayin da lorazepam ba. Wasu kwayoyi na iya toshe waɗannan enzymes, wanda ke shafar yadda ake sarrafa diazepam a cikin jiki. Wannan na iya haifar da ƙarin tasirin illa na diazepam. Magunguna kamar ketoconazole, cimetidine, da omeprazole na iya hulɗa tare da diazepam kuma suna haifar da ƙara shaƙuwa.
Antacids kamar calcium carbonate da magnesium hydroxide na iya rage shayar diazepam a cikin jiki. Wannan tasirin na iya canza yadda diazepam yake aiki.
| Drug | Ajin magani | Lorazepam | Diazepam |
| Oxycodone Hydrocodone Codein Morphine | Opioid | Ee | Ee |
| Phenobarbital Pentobarbital Secobarbital | Barbiturate | Ee | Ee |
| Clozapine Lurasidone Olanzapine | Antipsychotic | Ee | Ee |
| Fluoxetine Fluvoxamine Amitriptyline Doxepin | Maganin Ciwon Kai | Ee | Ee |
| Matsayi Phenytoin Clobazam | Mai cin nasara | Ee | Ee |
| Probenecid | Wakilin Antigout | Ee | Ee |
| Gagarini Aminophylline | Methylxanthine | Ee | Ee |
| Ketoconazole | Wakilin Antifungal | Ba | Ee |
| Cimetidine | H2-mai karɓar mai karɓa | Ba | Ee |
| Omeprazole | Proton famfo mai hanawa | Ba | Ee |
| Cardi mai amfani Magnesium hydroxide | Antacid | Ba | Ee |
Tuntuɓi ƙwararren masanin kiwon lafiya don sauran hanyoyin hulɗa da ƙwayoyi.
Gargadi na lorazepam da diazepam
Ya kamata a guji amfani da opioids tare da benzodiazepines. Idan ana amfani dasu tare, benzodiazepines da opioids na iya ƙara haɗarin ɓacin rai na numfashi, coma, har ma da mutuwa. Ya kamata a sanya wa marasa lafiya ido sosai lokacin da ake ɗaukar waɗannan azuzuwan magunguna biyu.
Lorazepam da diazepam sune Jadawalin IV magunguna . Waɗanda ke da tarihin da ya gabata na shaye-shaye ko kayan maye na iya kasancewa cikin haɗarin dogaro da zagi da benzodiazepines. Dogaro da zagi na iya ƙara haɗarin wuce haddi tare da benzodiazepines. Alamomi da alamomin shan kwayar cutar ta benzodiazepine sun hada da tsananin asara na daidaito, hawan jini mai hadari (hypotension), bacin rai na numfashi, da kuma suma.
Ya kamata a yi amfani da kashi mafi ƙarancin tasiri na lorazepam ko diazepam. Tuntuɓi likita ko ƙwararren masanin kiwon lafiya akan wasu faɗakarwa da kiyayewa.
Tambayoyi akai-akai game da lorazepam vs. diazepam
Menene lorazepam?
Lorazepam shine asalin sunan Ativan. Yana daga cikin nau'ikan magungunan da ake kira benzodiazepines. Ana samun Lorazepam azaman kwamfutar baka a ƙarfin 0.5 MG, 1 MG, da 2 MG. Hakanan za'a iya gudanar dashi azaman maganin baka ko allura. Lorazepam an yarda dashi don magance damuwa da rashin bacci wanda damuwa ta haifar. Hakanan za'a iya amfani dashi azaman magani don rikicewar rikicewar cuta ko premedication kafin tiyata.
Menene diazepam?
Diazepam kuma sanannen sanannen sa, Valium. Benzodiazepine ne wanda aka yarda da FDA don magance damuwa, cututtukan cire barasa, kuma jijiyoyin tsoka . Hakanan za'a iya amfani dashi don rikicewar rikice-rikice da dalilai na kwantar da hankali kafin tiyata. Ana samun Diazepam a cikin 2 mg, 5 mg, da 10 mg na roba. Hakanan yana zuwa azaman maganin baka, allura, da gel na dubura.
Shin lorazepam da diazepam iri daya ne?
Lorazepam da diazepam dukansu benzodiazepines ne, amma ba iri ɗaya bane. Sun zo cikin tsari daban-daban kuma suna da amfani daban-daban na FDA. Hakanan suna da ƙuntatawa na shekaru daban-daban: Ba a ba da shawarar Lorazepam a cikin yara 'yan ƙasa da shekaru 12 yayin da ba a ba da shawarar diazepam a cikin jariran da ke ƙasa da watanni 6.
Shin lorazepam ko diazepam sun fi kyau?
Lorazepam da diazepam duka magunguna ne masu tasiri. Diazepam yana dadewa a cikin jiki fiye da lorazepam. Koyaya, wannan baya nufin yana da magani mafi kyau. Ingancin benzodiazepine zai dogara ne da yanayin da ake bi da shi, tsakanin sauran abubuwan. Tuntuɓi mai ba da lafiya don ƙayyade mafi kyawun magani a gare ku.
Zan iya amfani da lorazepam ko diazepam yayin da nake da juna biyu?
Ba a ba da shawarar shan lorazepam ko diazepam yayin da take da ciki. Kodayake diazepam na iya zama mafi aminci fiye da lorazepam a lokacin daukar ciki, bai isa ba bincike ya nuna cewa benzodiazepines suna da cikakkiyar aminci yayin da suke da juna biyu. Tuntuɓi mai ba da kiwon lafiya kafin ɗaukar benzodiazepine yayin ɗaukar ciki.
Zan iya amfani da lorazepam ko diazepam tare da barasa?
Hada barasa da benzodiazepines ba da shawarar. Dukansu barasa da benzodiazepines na iya haifar da tasirin CNS kamar su bacci da jiri. Samun waɗannan abubuwan tare na iya ƙara haɗarin illa da ƙari.
Shin 3 mg lorazepam yayi yawa?
Sashin madaidaicin lorazepam zai dogara ne akan yanayin da ake bi. Tuntuɓi likita don shawarwarin likita na ƙwararru da umarnin da ya dace kan yadda ake amfani da wannan magani. Matsakaici na lorazepam zai iya zama ko'ina daga 2 zuwa 6 MG ta baki sau biyu zuwa uku a kowace rana.
Shin diazepam yana wucewa fiye da lorazepam?
Diazepam ya dade fiye da lorazepam. Anyi la'akari da shi azaman benzodiazepine mai tsayi tare da rabin rai na zuwa awanni 48. Benzodiazepines na dogon lokaci sun hada da Valium (diazepam), Librium (chlordiazepoxide), da Dalmane (flurazepam).
Shin ba kyau a ɗauki Ativan kowace rana?
Gabaɗaya ba a ba da shawarar ɗaukar Ativan (lorazepam) na dogon lokaci. Ba a gudanar da cikakken karatu ba kan aminci da tasirin Ativan watanni huɗu da aka yi amfani da su. Wasu mutane suna haɓaka dogara da haƙuri ga Ativan, wanda zai iya shafar yadda yake aiki a kan lokaci. Ya kamata ayi amfani da Ativan kawai kamar yadda mai ba da sabis na kiwon lafiya ya tsara.
Shin lorazepam yana aiki da sauri?
Lorazepam yana aiki ne na tsaka-tsakin benzodiazepine. Ana iya jin tasirin lorazepam cikin awa 1 zuwa 1.5 bayan shan sa. Rabin rabin lorazepam yana kusan awanni 10 zuwa 20. Sauran masu amfani da benzodiazepines sun hada da Xanax (alprazolam), Klonopin (clonazepam), da Restoril (temazepam).
