Pravastatin vs. Lipitor: Bambanci, kamance, kuma wanne ne mafi alheri a gare ku
Magunguna vs. AbokiBayanin magunguna & manyan bambance-bambance | Yanayin da aka bi | Inganci | Inshorar inshora da kwatancen farashi | Sakamakon sakamako | Hadin magunguna | Gargadi | Tambayoyi
Pravastatin da Lipitor (atorvastatin) sune magungunan likitanci da ake amfani dasu don magance babban cholesterol. Matakan cholesterol wadanda suke sama da yadda zasu saba na iya kara barazanar kamuwa da cututtukan zuciya, cututtukan jijiyoyin jini, bugun zuciya, da shanyewar jiki. Ana samar da ƙwayar cholesterol a cikin hanta ta hanyar HMG-CoA reductase enzyme.
Pravastatin da atorvastatin su ne magunguna waɗanda aka lasafta su azaman masu hana HMG-CoA reductase. Hakanan an san shi azaman ƙwayoyin statin, pravastatin da atorvastatin hanawa, ko toshewa, HMG-CoA reductase enzyme, wanda ke haifar da raguwar yawan ƙwayar cholesterol a cikin hanta. Amfani da statins shima yana kara adadin masu karban LDL (low-density lipoprotein) a cikin hanta, wanda ke taimakawa ƙananan matakan LDL, ko mummunan nau'in cholesterol, a cikin jini.
Dukansu pravastatin da atorvastatin suna aiki iri ɗaya, amma suna da wasu bambance-bambance da yakamata su sani.
Menene manyan bambance-bambance tsakanin pravastatin da Lipitor?
Pravastatin shine ainihin sunan Pravachol. Ba kamar sauran magungunan ƙwayoyi ba, pravastatin ba shi da cikakkiyar narkewa, ko sarrafawa, ta hanyar CYP3A4 enzymes a cikin hanta. Madadin haka, pravastatin shine karye cikin ciki .
Ana samun kwayoyi masu amfani da Pravastatin a cikin ƙarfin 10 MG, 20 MG, 40 MG, da 80 MG. Pravastatin yawanci ana ba da umarnin shan sau ɗaya kowace rana da yamma. An nuna cewa pravastatin ya fi tasiri yayin ɗauka da yamma maimakon da safe.
Lipitor magani ne mai suna kuma ana samun shi a cikin sifa iri iri da ake kira atorvastatin. Ba kamar pravastatin ba, atorvastatin ana sarrafa shi ta hanyar CYP3A4 enzyme a cikin hanta. Sabili da haka, atorvastatin na iya yuwuwar yin hulɗa tare da ƙarin magunguna fiye da pravastatin.
Ana samun lebe a cikin allunan baka tare da ƙarfin 10 MG, 20 MG, 40 MG, da kuma 80 MG. Ana iya shan lefe da safe ko yamma, kuma yawanci ana shan sa sau daya a rana.
| Babban banbanci tsakanin pravastatin da Lipitor | ||
|---|---|---|
| Pravastatin | Lashin mai | |
| Ajin magani | HMG-CoA mai hana hanawa | HMG-CoA mai hana hanawa |
| Alamar alama / ta kowa | Nau'in samfura da na yau da kullun akwai | Nau'in samfura da na yau da kullun akwai |
| Menene sunan jimla? Menene sunan alamar? | Sunan alama: Pravachol Suna na kowa: Pravastatin | Sunan mai suna: Lipitor Suna na gaba ɗaya: Atorvastatin |
| Wani nau'i (s) ne miyagun ƙwayoyi ya shigo? | Rubutun baka | Rubutun baka |
| Menene daidaitaccen sashi? | 10 zuwa 80 MG sau ɗaya a rana | 10 zuwa 80 MG sau ɗaya a rana |
| Yaya tsawon maganin al'ada? | Dogon lokaci | Dogon lokaci |
| Wanene yawanci yake amfani da magani? | Manya; yara da matasa masu shekaru 8 zuwa 18 | Manya; yara da matasa masu shekaru 10 zuwa 17 |
Yanayin da pravastatin da Lipitor suka kula dashi
Pravastatin da atorvastatin na iya taimakawa rage haɗarin bugun zuciya da shanyewar jiki a cikin mutanen da ke fama da cututtukan zuciya. Dukkanin magunguna guda biyu na iya taimakawa rage haɗarin mutuwa daga ciwon zuciya . Abubuwan haɗari ga cututtukan zuciya sun haɗa da hawan jini, shan sigari, da hauhawar matakan cholesterol.
Dukansu pravastatin da atorvastatin duka an amince da FDA don rage ƙimar duka-cholesterol da matakan LDL (wanda kuma aka sani da hyperlipidemia ko hypercholesterolemia). Hakanan magungunan na Statin na iya taimakawa wajen magance su dagagge matakan triglycerides , waxanda suke da wani nau'in kitse ko kitse a jiki. Wani da ke da hauhawar matakan triglycerides yana da cutar hauhawar jini.
Pravastatin da Lipitor suna iya ƙara matakan HDL a cikin jini. HDL cholesterol shine abin da aka sani da kyakkyawan cholesterol a cikin jini.
| Yanayi | Pravastatin | Lashin mai |
| Hyperlipidemia | Ee | Ee |
| Hypercholesterolemia | Ee | Ee |
| Hyttriglyceridemia | Ee | Ee |
Shin pravastatin ko Lipitor sun fi tasiri?
Dukansu pravastatin da atorvastatin suna da magunguna masu tasiri don magance yawan ƙwayar cholesterol na jini. Magungunan da ya fi tasiri ya dogara da yanayinku gabaɗaya, ƙarancin yanayinku, sauran ƙwayoyi da zaku iya sha, da sauran dalilai.
Daya nazarin kwatanta gano cewa babu wani bambanci mai mahimmanci tsakanin pravastatin, simvastatin, da atorvastatin don hana abubuwan da suka shafi zuciya da jijiyoyin jini. A takaice dai, wadannan magungunan suna da tasiri iri ɗaya don rage cututtukan zuciya da cututtukan zuciya.
ZUWA nazari na yau da kullun wanda ya haɗu a kan gwaji na asibiti na 90 idan aka kwatanta da magungunan statin kamar fluvastatin, atorvastatin, pravastatin, simvastatin, da rosuvastatin. Binciken ya kammala cewa atorvastatin, fluvastatin, da simvastatin suna da mafi girman yiwuwar kasancewa mafi kyawun magani don hana abubuwan da suka shafi zuciya da jijiyoyin jini.
Tuntuɓi mai ba da sabis na kiwon lafiya don ƙayyade mafi kyawun maganin ƙwayar cuta a gare ku. Bayan gudanar da gwajin jini da kimanta duk yanayin ku, mai bayarwa zai iya tantance ko pravastatin ko atorvastatin magani ne mafi inganci a gare ku. Hakanan zasu iya rubuta wani magani na daban kamar Zocor (simvastatin) ko Crestor (rosuvastatin).
Verageaukar hoto da kwatancen farashi na pravastatin vs. Lipitor
Pravastatin magani ne na asali wanda yawanci ana rufe shi ta Medicare da tsare-tsaren inshora. Matsakaicin farashin kuɗi na pravastatin yana kusan $ 129.99 don samarwa na kwanaki 30. Katin ajiya na SingleCare na iya iya rage farashin takardar sayen magani zuwa ƙasa da $ 15.
Lipitor magani ne mai suna wanda kuma ana samun shi a cikin mai rahusa, sigar asali. Sashin jigilar Lipitor, atorvastatin, yawanci ana rufe shi ta yawancin Medicare da tsare-tsaren inshora. Alamar sunan Lipitor na iya rufe tsarin inshora tare da babban biyan kuɗi. Farashin kuɗi na Lipitor yana kusan $ 249.99. Takaddun shaida na SingleCare na iya rage farashin zuwa $ 15 a shagunan sayar da magani.
| Pravastatin | Lashin mai | |
| Yawanci inshora ke rufe shi? | Ee | Ee |
| Yawanci an rufe shi ta Medicare Part D? | Ee | Ee |
| Yawan | 30 allunan (40 MG) | 30 allunan (40 MG) |
| Hanyar biyan kuɗaɗe na Medicare | $ 0– $ 20 | $ 0 - $ 16 |
| SingleCare kudin | $ 12 + | $ 15 + |
Sakamakon illa na yau da kullun na pravastatin vs. Lipitor
Abubuwan da aka fi sani na pravastatin sune musculoskeletal ko ciwon tsoka, tashin zuciya, amai, gudawa, da ciwon kai. Sakamakon illa na atorvastatin shine musculoskeletal ko ciwon tsoka, gudawa, da ciwon haɗin gwiwa (arthralgia). Dukansu pravastatin da atorvastatin suna iya haifar da wasu sakamako masu illa kamar rashin narkewar abinci, jiri, kasala, kurji, da cututtukan fitsari.
Tsanani sakamako masu illa na magungunan statin sun hada da cututtukan tsoka (myopathy) da saurin lalacewar tsoka (rhabdomyolysis). Tuntuɓi mai ba da sabis na kiwon lafiya nan da nan idan kun ji ciwo ko rauni, rauni, ko taushi.
Pravastatin da atorvastatin na iya haifar da haɓakar hanta enzymes. Matakan enzyme na hanta na iya buƙatar a bincika kafin a sa ido a cikin magani.
| Pravastatin | Lashin mai | |||
| Sakamakon sakamako | Ana amfani? | Mitar lokaci | Ana amfani? | Mitar lokaci |
| Ciwon tsoka | Ee | 10% | Ee | 4% |
| Tashin zuciya / amai | Ee | 7% | Ee | 4% |
| Gudawa | Ee | 7% | Ee | 7% |
| Rashin narkewar abinci | Ee | 3% | Ee | 5% |
| Dizziness | Ee | 4% | Ee | * |
| Ciwon kai | Ee | 6% | Ba | - |
| Gajiya | Ee | 3% | Ee | * |
| Rash | Ee | 5% | Ee | * |
| Arthralgia | Ee | * | Ee | 7% |
| Cutar fitsari | Ee | 3% | Ee | 6% |
Mitar ba ta dogara da bayanai daga gwajin kai-da-kai. Wannan na iya zama ba cikakken jerin tasirin illa bane wanda zai iya faruwa. Da fatan za a koma zuwa likitanku ko mai ba da sabis na kiwon lafiya don ƙarin koyo.
Source: DailyMed ( Pravastatin ,, DailyMed ( Lashin mai )
* ba'a ruwaito ba
Magungunan ƙwayoyi na pravastatin vs. Lipitor
Pravastatin da atorvastatin suna hulɗa tare da magunguna iri ɗaya. Koyaya, tunda atorvastatin yana haɓaka ta farko ta CYP3A4 enzyme a cikin hanta, yana iya hulɗa tare da ƙarin magungunan da ke shafar CYP3A4 enzymes a cikin hanta.
Shan magunguna kamar cyclosporine, clarithromycin, ko ritonavir tare da pravastatin ko atorvastatin na iya haifar da ƙarin matakan statin a cikin jini, wanda zai iya ƙara haɗarin mummunan sakamako.
Antacids na iya tsoma baki tare da sha da magungunan statin kuma rage tasirin su. Ya kamata a raba gudanar da maganin antacids da statins aƙalla awanni biyu. Cholestyramine kuma na iya rage sha da tasirin statins. Gudanar da cholestyramine da statins ya kamata a raba su da awanni huɗu.
Niacin da fibrates na iya ƙara haɗarin cutar ƙwaƙwalwa da rhabdomyolysis idan aka ɗauke su da pravastatin ko atorvastatin.
Yin amfani da atorvastatin ya kamata a guji ko sanya ido yayin cinyewa ruwan inabi . Ruwan inabi yana aiki a matsayin mai hana CYP3A4 wanda zai iya haifar da ƙarin matakan atorvastatin a cikin jini kuma ya ƙara haɗarin illa.
| Drug | Ajin magani | Pravastatin | Lashin mai |
| Cyclosporine | Immunosuppressants | Ee | Ee |
| Clarithromycin Erythromycin | Maganin rigakafi | Ee | Ee |
| Ketoconazole Itraconazole Voriconazole Posaconazole | Antifungals | Ba | Ee |
| Ritonavir Tsubirin Ledipasvir Boceprevir Darunavir | Kwayar rigakafi | Ee | Ee |
| Niacin | Ma'aikatan rigakafin cutar | Ee | Ee |
| Fenofibrate Gemfibrozil | Fibrates | Ee | Ee |
| Digoxin | Cardiac glycosides | Ee | Ee |
| Cholestyramine | Yan biyun acid Bile | Ee | Ee |
| Aluminum hydroxide Magnesium hydroxide | Antacids | Ee | Ee |
Tuntuɓi ƙwararren masanin kiwon lafiya don sauran hanyoyin hulɗa da ƙwayoyi.
Gargadi na pravastatin da Lipitor
Ya kamata a guji Pravastatin da atorvastatin a cikin waɗanda ke da cutar hanta mai aiki ko haɓakar enzyme mai hanta mai haɗari. Magungunan Statin na iya haifar da ƙarin lalacewar hanta a cikin wani mai cutar hanta.
Bai kamata a yi amfani da Pravastatin da atorvastatin a cikin waɗanda ke da tarihin halayen rashin kuzari game da magungunan statin ba. Alamomi da alamomin saurin kumburi sun hada da kurji, kaikayi, kumburi, da matsalar numfashi.
Magungunan Statin suna da haɗarin mummunan rauni na tsoka da ciwon tsoka. Akwai yiwuwar ƙara yawan haɗarin ciwon tsoka a cikin waɗanda suka haura shekaru 65 ko kuma waɗanda ke da cutar hypothyroidism ko matsalolin koda.
Bai kamata a yi amfani da Pravastatin da atorvastatin a cikin waɗanda ke da ciki ko masu shayarwa ba.
Yi magana da mai ba da sabis na kiwon lafiya don tattauna sauran gargaɗin da za a iya yi ko kiyayewa da ke haɗuwa da pravastatin ko atorvastatin.
Tambayoyi akai-akai game da pravastatin vs. Lipitor
Menene pravastatin?
Pravastatin magani ne na yau da kullun da ake amfani dashi don rage cholesterol da kuma hana rikice-rikicen da ke tattare da matakan cholesterol mai girma. Sunan sunan pravastatin shine Pravachol. An tsara cewa za a sha sau ɗaya a rana da yamma. Ana samun Pravastatin azaman kwamfutar hannu ta baka.
Menene Lipitor?
Lipitor magani ne mai suna wanda kamfanin Pfizer yayi. Sunan Lipitor na yau da kullun shine atorvastatin. Ana amfani dashi don magance yawan ƙwayoyin cholesterol da rage haɗarin bugun zuciya da bugun jini. An ba da liba a sha sau ɗaya sau ɗaya safe da yamma. Ana samunsa azaman kwamfutar hannu ta baka.
Shin pravastatin da Lipitor iri daya ne?
Dukansu pravastatin da atorvastatin sune magunguna da ake amfani dasu don rage yawan matakan cholesterol. Koyaya, ba ɗaya suke ba. Atorvastatin yana daɗaɗawa ta cikin tsarin enzyme na CYP P450 a cikin hanta yayin da pravastatin ya lalace cikin ciki. Pravastatin yawanci ana ɗaukarsa da dare yayin da ake shan Lipitor da safe ko yamma.
Shin pravastatin ko Lipitor ne mafi kyau?
Dukansu pravastatin da Lipitor suna da tasiri mai kyau na maganin statin. Dukkanin magunguna guda biyu na iya taimakawa wajen hana rikitarwa na yawan matakan cholesterol, kamar atherosclerosis, ciwon zuciya, da bugun jini. Wasu karatu daga mujallolin zuciya sun gano cewa atorvastatin, sinadarin aiki a cikin Lipitor, ya fi sauran magungunan ƙwayoyi ƙarfi don hana abubuwan da suka shafi zuciya kamar bugun zuciya da bugun jini. Mai ba da sabis na kiwon lafiya na iya ba da shawara na likita game da mafi kyawun maganin sihiri a gare ku.
Zan iya amfani da pravastatin ko Lipitor yayin da nake da juna biyu?
Ba a ba da shawarar a dauki Pravastatin da atorvastatin yayin da suke da juna biyu ba. Dukansu magunguna suna da babban haɗarin haifar da lahani na haihuwa. Tuntuɓi mai ba da sabis na kiwon lafiya don jagora kan mafi kyawun magani don ƙwanƙwasa ƙwayar cholesterol yayin ɗauke da ciki.
Zan iya amfani da pravastatin ko Lipitor tare da barasa?
Babu wani mummunan haɗarin lafiyar da ke tattare da matsakaiciyar shan giya da statins. Miyagun ƙwayoyi da yawan shan barasa na iya lalata hanta . Yi magana da mai ba da kiwon lafiya don tantance ko lafiyarka shan giya yayin shan shan magani.
