Estrace vs. Premarin: Bambanci, kamanceceniya, kuma wanene yafi muku alheri
Magunguna vs. AbokiBayanin magunguna & manyan bambance-bambance | Yanayin da aka bi | Inganci | Inshorar inshora da kwatancen farashi | Sakamakon sakamako | Hadin magunguna | Gargadi | Tambayoyi
Idan ka gamu da alamomin haila, kamar su zafi mai zafi, zufa na dare , matsalolin bacci, da rashin bushewar farji, mai ba da kiwon lafiya na iya ambaci maganin maye gurbin hormone ko maganin estrogen. Alamomin jinin haila suna faruwa ne lokacin da jiki yake yin karancin estrogen, don haka magungunan da ke maye gurbin estrogen na iya taimakawa wajen inganta wadannan alamun, kuma suna taimakawa wajen hana cutar sanyin kashi.
A cikin matan da ke da mahaifa, maganin farji ya hada da estrogen da progesterone. A cikin matan da ke da mahaifa, estrogen kadai ke ƙara haɗarin cutar kansa ta endometrial.
Mata ba tare da mahaifar mahaifa ba (waɗanda suka yi hysterectomy) ba sa buƙatar shan progesterone tare da estrogen. Waɗannan matan na iya amfani da kayayyakin isrogen kawai kamar Estrace ko Premarin.
Estrace da Premarin wasu sunaye ne guda biyu-masu suna waɗanda aka nuna don maganin cututtukan menopause. Dukkanin magungunan sun sami karbuwa daga Hukumar Abinci da Magunguna ta Amurka (FDA). Suna cikin rukunin magunguna da ake kira estrogens kuma ana kuma san su da maganin maye gurbin hormone. Ana samun su a cikin tsari daban-daban, gami da mayukan shafawa da alluna. Kodayake duka Estrace da Premarin suna dauke da sinadarin estrogen, amma ba daidai suke ba. Ci gaba da karatu don ƙarin koyo game da Estrace da Premarin.
Menene manyan bambance-bambance tsakanin Estrace da Premarin?
Estrace yana nan cikin alama da nau'ikan tsari kuma yana ƙunshe da sinadarin estradiol . Estrace yana samuwa azaman farjin estrogen na farji, kuma azaman kwamfutar hannu ta baka.
Premarin yana wadatar azaman samfurin sunan kawai. Ya ƙunshi mahaɗa estrogens, tsarkakakke daga fitsarin ciki mares (saboda haka sunan Premarin- PRE pregnant MARes urINe). Premarin yana samuwa azaman farjin estrogen na farji, ƙaramin baka, ko allura.
| Babban bambanci tsakanin Estrace da Premarin | ||
|---|---|---|
| Estrace | Premarin | |
| Ajin magani | Estrogens / maganin maye gurbin hormone | Estrogens / maganin maye gurbin hormone |
| Alamar alama / ta kowa | Brand da janar | Alamar |
| Menene sunan gama-gari? | Estradiol | Haɗa estrogens |
| Wani nau'i (s) ne miyagun ƙwayoyi ya shigo? | Kirjin farji, na roba na baka | Kirjin farji, tabo na baka, allura |
| Menene daidaitaccen sashi? | Kirim: Giram 2 zuwa 4 na cikin gida kowace rana na tsawon makonni 1-2, sannan a hankali a rage zuwa nauyin gyara gram 1 sau 1-3 a mako Allunan: ya bambanta | Kirim: 0.5 gram a cikin sau biyu a mako Allunan: ya bambanta |
| Yaya tsawon maganin al'ada? | Ya bambanta | Ya bambanta |
| Wanene yawanci yake amfani da magani? | Mata masu auren miji, lokaci-lokaci a cikin maza don wasu alamomi (duba ƙasa) | Mata masu auren miji, lokaci-lokaci a cikin maza don wasu alamomi (duba ƙasa) |
Yanayin da Estrace da Premarin suka kula da shi
Kirim mai suna Estrace cream da Premarin cream suna magance matsakaiciyar cutar mai saurin kamuwa da cutar farji da mara na jiki (saukuwa, bushewa, da kumburi) saboda al'adar maza.
A cikin nau'in kwamfutar hannu, Estrace da Premarin suna bi da wasu sharuɗɗan da aka lissafa a cikin jadawalin da ke ƙasa.
| Yanayi | Estrace | Premarin |
| Matsakaici zuwa mai tsananin alamun bayyanar cututtukan mara / farji saboda al'adar maza | Ee (kirim) | Ee (kirim) |
| Jiyya na hypoestrogenism saboda hypogonadism, castration, ko gazawar ƙwai na farko | Ee (kwamfutar hannu) | Ee (kwamfutar hannu) |
| Maganin kansar nono (don sauƙaƙa kawai) a cikin wasu mata da maza masu cutar metastatic | Ee (kwamfutar hannu) | Ee (kwamfutar hannu) |
| Jiyya na ci gaban cututtukan ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta (don sauƙaƙe kawai) | Ee (kwamfutar hannu) | Ee (kwamfutar hannu) |
| Rigakafin cutar sankara bayan haihuwa ga mata masu babban haɗari, lokacin da magungunan da ba na estrogen ba su dace | Ee (kwamfutar hannu) | Ee (kwamfutar hannu) |
| Jiyya na atrophic vaginitis da kraurosis vulvae | Kashe-lakabi | Ee (kirim) |
| Maganin matsakaiciyar cuta mai tsanani na dyspareunia (saduwa mai raɗaɗi) saboda al'adar maza | Kashe-lakabi | Ee (kirim) |
| Jiyya na alamomin cutar vasomotor masu matsakaici zuwa na al'ada | Ee (kwamfutar hannu) | Ee (kwamfutar hannu) |
Shin Estrace ko Premarin sun fi tasiri?
Nazarin ya nuna cewa yayin gwada kayayyakin isrogen, estradiol (sinadarin Estrace) da conjugated estrogens (sashin a cikin Premarin) suna da tasiri daidai wajan magance alamomin jinin haila. Manyan farji suna da tasiri kuma an jure da kyau.
Mai ba da sabis na kiwon lafiya na iya ƙayyade wane magani ya dace da ku, la'akari da alamun ku, yanayin kiwon lafiya, da tarihin lafiyar ku.
Verageaukar hoto da kwatancen farashi na Estrace vs. Premarin
Inshora da shirin likitancin likita galibi sun hada da Estrace da Premarin.
Takaddun tsarin jigilar Estrace na kwalliya na kirim ne kuma yana kashe kusan $ 36 idan kun biya daga aljihu, amma yin amfani da coupon kyauta na SingleCare na iya kawo farashin ƙasa da $ 6.
Takaddun magani na yau da kullun don bututun Premarin yakai kimanin $ 250 daga aljihu. Katin SingleCare na iya kawo farashin zuwa ƙasa kamar $ 198.
Yayinda tsare-tsaren suka bambanta, tuntuɓi mai ba da inshorar ku don cikakkun bayanan ɗaukar hoto.
| Estrace | Premarin | |
| Yawanci inshora ya rufe? | Ee | Ee |
| Yawanci an rufe shi ta Medicare Part D? | Ee | Ee |
| Yawan | 1 bututu | 1 bututu |
| Hanyar biyan kuɗaɗe na Medicare | $ 1- $ 36 | $ 2 - $ 451 |
| SingleCare kudin | $ 6 + | $ 198 + |
Illolin gama gari na yau da kullun na Estrace vs. Premarin
Abubuwan da suka fi dacewa na Estrace da cream na Premarin sun haɗa da halayen aikace-aikacen aikace-aikace kamar ƙaiƙayi, fitarwa, zubar jini na mahaifa, da kumburi. Bugu da ƙari, ciwon kai da ƙashin ƙugu na iya faruwa. Ba a haɗa yawan tasirin abubuwan illa a cikin bayanin ƙayyadewa na Estrace.
Illolin yau da kullun na Estrace da Premarin a cikin nau'in kwamfutar hannu sun fi tsari. Wasu daga cikin wadannan illolin sun hada da ciwon ciki ko na baya, rauni, kumburi, ciwon kai, maƙarƙashiya, gas, tashin zuciya, riba mai nauyi, ɓacin rai, tashin hankali, jiri, raɗaɗin ciki / zafi / canje-canje, da zubar ruwan farji, zubar jini, ko kamuwa da yisti.
Wannan ba cikakken lissafin sakamako bane. Sauran illolin na iya faruwa. Tuntuɓi mai ba da lafiyar ku don tattauna irin illar da za ku yi tsammani, da yadda za a magance su.
| Kirim mai tsami | Premarin kirim | |||
| Sakamakon sakamako | Ana amfani? | Mitar lokaci | Ana amfani? | Mitar lokaci |
| Ciwon kai | Ee | % ba a ruwaito ba | Ee | 3-5% * |
| Ciwon mara | Ee | % ba a ruwaito ba | Ee | 4% |
| Itching | Ee | % ba a ruwaito ba | Ee | 1-2% |
| Fitowar farji | Ba | - | Ee | 3-4% |
| Zubar jini ta farji | Ee | % ba a ruwaito ba | Ee | 1-2% |
| Kumburin farji | Ee | % ba a ruwaito ba | Ee | 1-2% |
| Farji ta farji / yisti kamuwa da cuta | Ee | % ba a ruwaito ba | Ee | 3-4% |
* ya dogara da yawan sashi
Source: DailyMed ( Kirim mai tsami ,, DailyMed ( Premarin kirim )
Magungunan ƙwayoyi na Estrace vs. Premarin
Estrace ko Premarin na iya shafar wasu ƙwayoyi waɗanda suke amfani da enzyme da ake kira cytochrome-p 450 3A4. Magungunan da ke hana enzyme na iya rage aikin sarrafa jiki na Estrace ko Premarin, ma’ana Estrace ko Premarin na iya zama a cikin jiki tsawon lokaci, yana haifar da ƙarin sakamako masu illa. Hakanan, magungunan da ke haifar da enzyme na iya haifar da jiki don sarrafa Estrace ko Premarin da sauri, yana mai da shi mara tasiri. Tuntuɓi mai ba da lafiyar ku game da yiwuwar hulɗar magunguna.
| Drug | Ajin magani | Estrace | Premarin |
| Clarithromycin Erythromycin Ruwan inabi Itraconazole Ketoconazole Ritonavir | CYP3A4 masu hana enzyme | Zai yiwu | Zai yiwu |
| Carbamazepine Phenobarbital Rifampin St John's wort | CYP3A4 enzyme masu haɓakawa | Zai yiwu | Zai yiwu |
Gargadi na Estrace da Premarin
Estrace da Premarin suna da gargaɗin dambe , wanda shine gargadi mafi karfi da FDA ke buƙata. Saboda shan tsari na yau da kullun zai iya faruwa tare da Estrace ko cream na Premarin, faɗakarwar tana amfani da dukkan hanyoyin.
Estrogen kadai:
- Yin amfani da estrogen shi kaɗai (ba tare da progesin ba) a cikin macen da ke da mahaifa yana ƙara haɗarin cutar kansa ta endometrial. Ara progestin zuwa maganin estrogen na iya rage haɗarin cutar sankarar mahaifa (amma zai iya ƙara haɗarin cutar sankarar mama). Yakamata a gwada mata masu haila bayan haila da jinin da bai dace ba don kaucewa cutar rashin lafiya.
- Kada a yi amfani da sinadarin estrogen shi kadai don hana kamuwa da cututtukan zuciya ko hauka. Shirin Kiwon Lafiya na Mata (WHI) karatu sami ƙarin haɗarin bugun jini da DVT (zurfin jijiyoyin jini, ko ƙuƙwarar jini a ƙafa) a cikin matan da suka wuce haihuwa waɗanda suka ɗauki estrogen ita kaɗai (ba tare da progesin ba).
- Binciken ya kuma nuna karin kasadar kamuwa da cutar mantuwa a matan da ba su kai aure ba wadanda suka dauki estrogen ita kadai.
Estrogen da progestin:
- Kada ayi amfani da estrogen tare da progestin don hana cututtukan zuciya ko hauka. Nazarin WHI ya samo haɗarin haɗari na DVT, PE (huhu na huhu), bugun jini, da MI a cikin matan da ba su gama aure ba waɗanda suka ɗauki estrogen da kuma progesin. Binciken ya kuma nuna kasadar kamuwa da cutar mantuwa a cikin matan da ba su kai aure ba wadanda suka dauki estrogen tare da progesin.
- Binciken WHI ya kuma nuna yawan haɗarin cutar sankarar mama tare da estrogen da progesin.
Sabili da haka, estrogens, ba tare da la'akari da ko an tsara su tare da ko ba tare da progesins ba, ya kamata a ba su a mafi ƙanƙanci kuma don mafi kankanin lokaci. Yi magana da mai ba da sabis na kiwon lafiya game da haɗarin rashin fa'idodi da nau'ikan nau'ikan maganin maye gurbin hormone.
Likitan ku zai ba ku shawarar likita kan dubawa. Duk mata yakamata suyi gwajin nono na shekara-shekara daga kwararrun likitocin kuma suyi gwajin kansu kowane wata. Duk mata yakamata su sami mammography dangane da shekaru, abubuwan haɗari, da tarihi.
Sauran gargaɗin Estrace da Premarin suna bi.
Kada kayi amfani da Estrace ko Premarin idan kana da:
- Zuban jini mara kyau wanda ba a gano shi ba
- Ciwon nono (sananne, wanda ake zargi, ko tarihi)
- Neoplasia mai dogaro da estrogen (sananne ko ake zargi)
- DVT ko embolism na huhu (aiki ko tarihi)
- Mai aiki ko tarihin cutar thromboembolic (bugun jini, MI)
- Hanyar rashin lafiyar da ta gabata game da estrogen
- Ciwon Hanta
- Cututtukan Thrombophilic
- Ciki (sananne ko ake zargi)
Haɗin haɗin haɗin haɗin haɗuwa (estrogen da progestin) na iya ƙara haɗarin cutar kansa ta ovarian.
Matanda suka gama haihuwa bayan haihuwa wadanda suke shan estrogen suna da karuwar kasadar kamuwa da cututtukan ciki wanda ke bukatar tiyata.
A cikin mutanen da suke ɗaukar estrogens, matsalolin gani sun faru. Nemi magani na gaggawa idan kuna da rashin gani (na juzu'i ko cikakke), hangen nesa biyu, kumburin ido, ko ƙaura.
A cikin al'amuran da ba safai ba, halayen rashin lafiyan sun faru. Idan kana da kumburi, kaikayi, wahalar numfashi, amai, ko kumburin fuska, lebe, harshe, hannaye, ko ƙafa, nemi likita na gaggawa kai tsaye. Maganin Estrogen na iya kara cutar cututtukan angioedema a cikin mata masu fama da cutar angioedema.
Yi magana da mai ba da lafiyar ka game da waɗannan haɗarin kafin shan Estrace ko Premarin, don ganin ko maganin yana da lafiya a gare ka.
Tambayoyi akai-akai game da Estrace vs. Premarin
Menene Estrace?
Estrace magani ne na maye gurbin hormone wanda ya ƙunshi estradiol. Ana amfani da shi don alamomi iri-iri, mafi yawan lokuta don alamomin jinin haila. Estrace yana samuwa azaman maganin intravaginal tare da kwamfutar hannu na baka.
Menene Premarin?
Premarin shima magani ne na maye gurbin hormone. Premarin ya ƙunshi mahaɗan estrogens. Ana amfani da shi don alamomi da yawa, galibi don alamomin menopause. Premarin yana samuwa azaman kwamfutar hannu ta baka, kirjin intravaginal, da allura.
Shin Estrace da Premarin iri daya ne?
Estrace da Premarin suna kama, amma ba daidai bane. Bayanin da ke sama ya nuna bambance-bambance tsakanin magunguna biyu.
Shin Estrace ko Premarin sun fi kyau?
Dukkanin magungunan suna da tasiri wajen magance alamomin haila, amma, waɗannan kwayoyi suna zuwa da illa da haɗari. Yi magana da mai baka sabis don sanin idan Estrace ko Premarin sun dace maka.
Zan iya amfani da Estrace ko Premarin yayin da nake da juna biyu?
A'a. Bai kamata a yi amfani da magani a ciki ba.
Zan iya amfani da Estrace ko Premarin tare da barasa?
Shan barasa a hade tare da Estrace ko Premarin iya ƙara haɗarin ku don ciwon nono. Tuntuɓi ƙwararren likitanku don jagora kan amfani da barasa tare da duk wani yanayin kiwon lafiya da kuke da shi.
Menene mafi kyawun madadin zuwa Premarin?
Estrace kwatankwacin madadin Premarin ne. Sauran magungunan da ke dauke da sinadarin 'estrogen' sun hada da Vivelle Dot Patch, Climara Patch, ko kuma kwayar halittar isrogen a cikin kwayar halittar farji ta Vagifem (allunan farji da ake amfani da su wajan shigar farji) ko kuma Estring Farji Na Farji. Yi magana da mai ba da sabis na kiwon lafiya don ganin ko ɗayan waɗannan magungunan sun dace da kai.
Shin estrogen da estradiol iri daya ne?
Estradiol wani nau'i ne na estrogen, hormone mace. Duk samfuran estradiol sune estrogen. Koyaya, akwai wasu siffofin estrogen fiye da estradiol kawai. Misali, conjugated estrogens (Premarin) wani nau'in estrogen ne.
Shin Premarin yana haifar da lalata?
Premarin (da Estrace) suna da gargaɗin dambe game da rashin hankali. Nazarin Memori na WHI da aka ambata a sama ya sami ƙarin haɗarin ɓarna a cikin matan da ba su gama aure ba waɗanda suka ɗauki estrogen ita kaɗai ko kuma estrogen tare da progestin. Sabili da haka, bayanin da aka ba da shawarar yana ba da shawarar cewa estrogen, ko an ɗauka shi kaɗai ko kuma tare da progestin, ya kamata a tsara shi a mafi ƙanƙanci kuma don mafi kankanin lokaci.
Shin Estrace yana haɓaka matakan estrogen?
Estrace (da Premarin) suna ƙaruwa matakan estrogen. Koda a cikin sifar farji, akwai nutsuwa ta tsari, kuma matakan estrogen suna ƙaruwa. Mai ba da lafiyar ku na iya tantance wane samfurin ya fi dacewa da ku.
