Main >> Magunguna Vs. Aboki >> Estriol vs. estradiol: Bambanci, kamance, kuma wanne ne mafi alheri a gare ku

Estriol vs. estradiol: Bambanci, kamance, kuma wanne ne mafi alheri a gare ku

Magunguna vs. Aboki

Estriol (E3) da estradiol (E2) siffofi ne daban daban daban guda biyu na mace mai suna estrogen (wani lokacin ana kiranta estrogen). Wadannan nau'ikan estrogen sune kwayoyin halittar steroid wadanda ake samu a zahiri a jiki. Ana iya amfani da Estriol da estradiol azaman maganin maye gurbin hormone (HRT) na mata bayan sun gama al'ada.

Estriol da estradiol su ne biyu daga cikin nau'ikan nau'ikan nau'ikan hodar iblis uku. Nau'in estrogen na uku shine estrone (E1), wanda ake samarwa ga mata yayin al'ada da kuma youngan matan da suke fuskantar farkon lokacinsu. Ba a yawan amfani da Estrone don HRT saboda ana ɗaukarsa estrogen mara ƙarfi.

Estrogens suna aiki ta ɗaure ga masu karɓar estrogen (ERα ko ERβ) a cikin jiki. Duk da yake wuraren su na iya ruɓewa, alpha receptor alpha (ERα) ana samun sa ne da farko a cikin endometrium, kayan nono, da ƙwai. Ana samun beta na karɓar isrogen (ERβ) a wasu sassan jiki kamar kwakwalwa, zuciya, kodoji, ƙasusuwa, da huhu.

Menene manyan bambance-bambance tsakanin estriol da estradiol?

Estriol (Estriol takardun shaida | Estriol details) wani lokacin ana kiransa E3 ko oestriol. Shine nau'in estrogen mafi rauni a jiki. Kamar estrone, matakan estriol suna ƙaruwa da sauƙi yayin daukar ciki. Estriol shine FDA da aka amince da shi don rashin matsalar fitsari a cikin karnukan mata bayan cire ƙwarjin ƙwai da mahaifa. Estriol ba FDA ta amince dashi azaman magani ba don mutane. Koyaya, wasu shagunan sayar da magani zasu iya siyar da sinadarin estriol wanda ya haɗu da wasu magunguna.

Estradiol (Estradiol takardun shaida | Bayanin Estradiol), ko E2, shine mafi ƙarfi daga cikin estrogens ɗin guda uku. Wasu nau'ikan estradiol ana iya samun su a cikin ƙananan ƙwayoyin maganin hana haihuwa don mata masu premenopausal. Ana amfani dashi da farko azaman kwamfutar hannu, faci, ko cream don maganin maye gurbin estrogen. Ana iya samun Estradiol a cikin samfuran da FDA ta amince da su kamar Estrace, Vivelle-Dot, Vagifem, da Climara, da sauransu. FDA ta kuma amince da estradiol a cikin bioidentical hormone far tare da progesterone.

Babban bambance-bambance tsakanin estriol da estradiol
	Estriol	Estradiol
Ajin magani	Estrogen	Estrogen
Alamar alama / ta kowa	Ana samun wadatar abubuwa	Ana samun wadatar abubuwa
Menene sunan alamar?	Incurin (don karnuka)	Estrace Vivelle-Dot Vagifem Climara
Wani nau'i (s) ne miyagun ƙwayoyi ya shigo?	Rubutun baka Kirim mai tsami Kirjin farji Sashin Farji	Rubutun baka Topical gel / jelly Kirjin farji Sashin Farji Zoben farji Transdermal faci
Menene daidaitaccen sashi?	Ya dogara da takardar likitan ku	Ya dogara da takardar likitan ku
Yaya tsawon maganin al'ada?	Tsawancin magani ya bambanta dangane da umarnin likitanku	Tsawancin magani ya bambanta dangane da umarnin likitanku
Wanene yawanci yake amfani da magani?	Manya	Manya

Kuna son mafi kyawun farashi akan estriol?

Yi rajista don faɗakarwar farashin estriol kuma gano lokacin da farashin ya canza!

Sami faɗakarwar farashi

Yanayin da estriol da estradiol suka kula da shi

Ana amfani da estrogen a matsayin maganin maye gurbin hormone ga mata waɗanda ke fuskantar alamomin jinin haila. Estrogens ana haɗuwa da su tare da progesterone ko wasu kwayoyin hormones da ake kira progesins. Estradiol shine FDA da aka yarda dashi don magance alamun rashin jinin al'ada. Wadannan alamomin sun hada da cututtukan vasomotor kamar su walƙiya mai zafi, zufa da dare, da kuma fatar fata. Sauran cututtukan da suka shafi menopausal sun hada da atrophy na farji, ko bushewar farji, kumburi, da siririya.

Hakanan za'a iya amfani da Estradiol a ƙarshen mataki kansar nono hakan ya yadu zuwa sauran sassan jiki. Ana amfani da shi don taimakawa rage ƙarancin ciwon daji (kulawar kwantar da hankali). Ga matan da ke da cutar ER-tabbatacce (ER +) kansar nono wanda ya daidaita, ana iya amfani da babban kwayar estradiol azaman far. A cewar karatu daga Balaga , idan ciwace-ciwacen mama sun bayyana kwayar halittar ta ESR1, cutar sankara na iya amsawa sosai ga maganin estradiol.

Hakanan an yarda da allunan Estradiol don magance ci gaba da ciwon sankara wanda ya dogara da inrogen. Yayin matakan estrogen na iya ba da gudummawa ga ciwon sankara, ana iya amfani da estradiol a matsayin magani na kwantar da hankali a cikin wasu maza. Nazarin nuna cewa estradiol ingantaccen tsari ne na magance wasu nau'ikan cututtukan sankara.

Estriol ba FDA-ta yarda dashi cikin mutane ba. Koyaya, wani lokacin ana haɗa shi da wasu magunguna don maganin maye gurbin hormone. Saboda shi estrogen ne, ana iya amfani dashi azaman magani wanda ba'a yiwa lakabi ba don yanayin yanayin estrogen. Hanyar estriol ta FDA wacce aka yarda da ita ita ce Incurin , wanda ke magance matsalar rashin yin fitsari a cikin karnukan mata bayan cirewar kwayayen da mahaifar (ovariohysterectomy).

Sauran kashe-lakabin amfani da estriol da estradiol sun hada da saukin bakin haure na haila da kuma rigakafin cutar sanyin kashi (kashi) bayan gama al'ada. Estrogen yana taka rawa a girman ƙashi. Matan da suka wuce maza da mata tare da rashi estrogen na iya samun ƙarancin ma'adinin ƙashi. Hakanan za'a iya amfani da maganin Estrogen don magance baƙin ciki bayan haihuwa. A cewar wasu karatu , transdermal estradiol ya nuna yana da amfani don saukaka bakin ciki bayan haihuwa.

Yanayi	Estriol	Estradiol
Maganin maye gurbin Hormone	Kashe-lakabi	Ee
Al'aura	Kashe-lakabi	Ee
Farjin mace ta farji	Kashe-lakabi	Ee
Alamomin Vasomotor	Kashe-lakabi	Ee
Ciwon nono (kulawa mai kwantar da hankali)	Kashe-lakabi	Ee
Ciwon daji na prostate mai girma (kulawa mai kulawa)	Kashe-lakabi	Ee
Rashin fitsari (don karnuka)	Ee	Ba
Ciwon mara na al'ada	Kashe-lakabi	Kashe-lakabi
Postmenopausal osteoporosis	Kashe-lakabi	Kashe-lakabi
Rashin ciki bayan haihuwa	Kashe-lakabi	Kashe-lakabi

Shin estriol ko estradiol sun fi tasiri?

Daga cikin sifofin uku na estrogen, estradiol shine mafi kyawun tsari . Hukumar Abinci da Magunguna ta Amurka ta amince da shi don magance yanayin da ke tattare da estrogen. Ba a yarda da Estriol da estrone a cikin Amurka don mata ba. Koyaya, ana iya amfani da waɗannan estrogens ɗin a cikin wasu magunguna masu haɗuwa.

Babu gwajin kai-da-kai da aka gudanar tare da estriol da estradiol. Wasu karatu sun nuna cewa estriol lafiyayye ne kuma mai tasiri ne ga alamomin jinin al'ada. Lokacin da aka yi amfani da shi kai tsaye don atrophy na farji, estriol ya kasance ya ruwaito ya zama mai tasiri tare da sauran magunguna. Saboda estriol ba shi da ƙarfi, yana iya samun ƙananan sakamako. Yin amfani da estriol, kamar sauran hanyoyin kwantar da cututtukan estrogen, har yanzu yana iya ƙara haɗarin cutar sankarar mama, hyperplasia na endometrial, da kansar endometrial.

Maganin Estradiol na iya zama mai amfani azaman HRT bayan gama al'ada. A zahiri, ita ce mafi yawan isrogen da aka tsara don alamomin jinin haila. Duk nau'ikan estradiol an yarda dasu don maganin maye gurbin hormone. Transaƙarin transdermal ya kasance aka nuna don haifar da matakan estrogen na kwari don ingantaccen magani.

Tuntuɓi mai ba da lafiyar ku don tattauna zaɓuɓɓukan ku idan kuna la'akari da magunguna waɗanda ke shafar matakan hormone. Ana iya ba da shawarar wasu nau'o'in estrogen kamar ƙwayoyi waɗanda ke ƙunshe da estrogens masu haɗuwa (misali, Premarin, Prempro).

Kuna son mafi kyawun farashi akan estradiol?

Yi rajista don faɗakarwar farashin estradiol kuma gano lokacin da farashin ya canza!

Sami faɗakarwar farashi

Verageaukar hoto da kwatancen farashi na estriol vs. estradiol

A halin yanzu, babu wasu magunguna da FDA ta amince da su dauke da estriol ga mutane. Sabili da haka, yawancin lokuta ba a rufe shi ta hanyar Medicare da tsare-tsaren inshora. Incurin shine sunan suna na estriol wanda aka yarda dashi don karnuka masu fama da matsalar yoyon fitsari. Kudin zai iya bambanta dangane da kantin magani da kuka siya daga. Babu rangwamen rangwamen SingleCare don estriol.

Estradiol yana nan a matsayin fata na fata. Sunayen estradiol sun hada da Minivelle, Climara, da Vivelle-Dot. Sunan mai suna estradiol matsakaicin farashin kuɗi na iya bambanta da shirin Medicare da tsare-tsaren inshora amma zaku iya sayan nau'ikan sihiri na $ 33- $ 63 tare da katin rangwame na SingleCare.

Nemi katin rangwame na SingleCare

	Estriol	Estradiol
Yawanci inshora ke rufe shi?	Ba	Ee
Yawanci Medicare ke rufe shi?	Ba	Ee
Daidaitaccen sashi	1 mg Allunan	1 zuwa 2 MG kowace rana
Hanyar biyan kuɗaɗe na Medicare	Ba a rufe ba	$ 0- $ 171
SingleCare kudin	Ba a ba da rangwamen kan Estriol ta hanyar SingleCare	$ 33- $ 63

Sakamakon sakamako na estriol da estradiol

Abubuwan da suka fi dacewa na ilimin estrogen sun hada da canjin al'ada (canje-canje a yanayin zubar jini), tabo, zafi yayin lokuta (dysmenorrhea), taushin nono, tashin zuciya, amai, da ciwon kai. Sauran cututtukan da ke tattare da isrogens na jiki da na baka sun hada da kumburin ciki, karin nauyi, da zubar gashi.

Topical estriol ko estradiol na iya haifar da ƙarin tasiri kai tsaye yayin amfani da farjin. Illoli na iya haɗawa da ƙaiƙayi da ƙara ɓoyewa. Sauran cututtukan da suka fi haɗari na iya haɗawa da cututtukan fungal (candidiasis).

An nuna estrogen don canzawa ko ƙarawa samar da melanin , sinadarin da ke haifar da launin fata. Estrogen na iya kara yawan launi da kuma yiwa fata duhu a wasu lokuta.

M sakamako mai illa na amfani da estrogen sun hada da hawan jini (hauhawar jini), bugun zuciya, toshewar jini (thromboembolism), cutar asma, cutar gallbladder, da kuma karancin matakan calcium. Sauran mummunan sakamako na iya haɗawa da faɗaɗa fibroids a cikin mahaifa da haɗarin mama da na sankarar mahaifa.

	Estriol	Estradiol
Tasirin Side	Ana amfani?	Mitar lokaci	Ana amfani?	Mitar lokaci
Canjin haila	Ee	* ba'a ruwaito ba	Ee	*
Ganowa	Ee	*	Ee	*
Dysmenorrhea	Ee	*	Ee	*
Taushin nono	Ee	*	Ee	*
Ciwan	Ee	*	Ee	*
Amai	Ee	*	Ee	*
Ciwon kai	Ee	*	Ee	*
Karuwar nauyi	Ee	*	Ee	*
Rashin gashi	Ee	*	Ee	*
Farji itching	Ee	*	Ee	*
Kumburin ciki	Ee	*	Ee	*
Canje-canje a cikin launin fata	Ee	*	Ee	*

Wannan na iya zama ba cikakken lissafi bane. Tuntuɓi likitan ku ko likitan magunguna don sauran tasirin.
Source: DailyMed ( Estriol ,, DailyMed ( Estradiol )

Magungunan ƙwayoyi na estriol vs. estradiol

Ana amfani da sinadarin Estrogen a cikin hanta ta hanyar CYP3A4 enzymes. CYP3A4 masu hanawa, kamar wasu maganin rigakafi, antifungals, steroids, da anticonvulsants, na iya ƙara matakan magungunan estrogenic a cikin jiki. Hakanan, wannan na iya ƙara haɗarin illa masu illa.

CYP3A4 masu shigar da ciki kamar wasu maganin rigakafi, antifungals, da antivirals na iya rage matakin estriol ko estradiol a cikin jini. Masu shigar da CYP3A4 na iya haifar da kyakkyawan tasiri tare da kwayoyi masu ƙunshe da estrogen. (Duba zane don misalai)

Estriol da estradiol kuma suna iya yin ma'amala da ruwan 'ya'yan inabi. Shan ruwan inabi tare da kayayyakin dake dauke da sinadarin estrogen na iya kara barazanar illa. Yana da mahimmanci a tattauna cikakken tarihin lafiyarku tare da likita wanda ya ƙware a cikin ilimin halittu.

Drug	Ajin Magunguna	Estriol	Estradiol
Clarithromycin Erythromycin Ketoconazole Itraconazole Cimetidine Ritonavir	Mai hana CYP3A4	Ee	Ee
St. John’s Wort Phenobarbital Phenytoin Carbamazepine Rifampin Dexamethasone	CYP3A4 mai gabatarwa	Ee	Ee

Wannan bazai zama cikakken jerin duk ma'amalar miyagun ƙwayoyi ba. Tuntuɓi likita tare da duk magungunan da za ku iya sha.

Gargadi na estriol da estradiol

Yin amfani da estrogen na iya kara haɗarin cutar sankara ta jiki, musamman lokacin da ba a ɗauka tare da progesin. Estriol da estradiol suma suna da haɗarin kamuwa da bugun zuciya (cututtukan zuciya), bugun jini, embolism na huhu (kumburin jini a cikin huhu), da zurfin jijiyoyin jini (kumburin jini a jijiyoyin) a cikin mata masu haihuwa bayan shekaru 50 zuwa 79. A cikin yawan matan, yin amfani da estrogen na iya haifar da ƙara haɗarin ciwon nono, a cewar Shirin Kiwon Lafiya na Mata . Hakanan Estrogen na iya ƙara haɗarin cutar ƙwaƙwalwa a cikin wasu matan da basu gama haihuwa ba bayan shekaru 65.

Tuntuɓi likita idan kuna da abubuwan haɗari ciki har da tarihin lafiya na:

Ciwon zuciya
Buguwa
Jinin jini
Ciwon daji (kowane nau'i)
Lokaci mara kyau
Hawan jini
Ciwon zuciya
Asthma
Ciwon ciki
Ciwon Hanta
Ciwon mahaifa
Ciwon mara
Hypocalcemia

Matan da ke shan sigari na iya kasancewa cikin haɗarin haɗarin ɗaurewar jini. Kada a yi amfani da kayayyakin da ke dauke da sinadarin Estrogen a cikin waɗannan matan.

Estriol, estradiol, da sauran kwayoyi masu alaƙa da estrogen na iya cutar da jaririn da ba a haifa ba. Bai kamata a yi amfani da su lokacin ciki ko shayarwa ba.

Tambayoyi akai-akai game da estriol vs. estradiol

Menene estriol?

Estriol wani nau’i ne na estrogen wanda ake samar dashi a jiki cikin jiki. Estriol ba FDA ta amince dashi ba don maye gurbin maye gurbin hoda a cikin mutane. Wasu hada-hada magunguna zasu iya siyar da magunguna dauke da sinadarin estriol wadanda ake amfani dasu don dalilai na lakabi. Estriol an yarda ne kawai don magance matsalar rashin fitsari a cikin karnukan mata.

Menene estradiol?

Estradiol shine mafi ƙarfin nau'in estrogen. Akwai shi a cikin nau'ikan nau'ikan nau'ikan daban-daban da nau'ikan halittu. Sunayen sunaye sun hada da Estrace, Climara, da Vivelle-Dot. Ana iya amfani dashi azaman kwamfutar hannu ta baka, transdermal patch, ko cream na farji ga mata masu alamomin haihuwa bayan haihuwa. Hakanan za'a iya amfani dashi azaman magani na kwantar da hankali don ƙarshen matakin nono da kansar prostate.

Shin estriol da estradiol iri daya ne?

A'a Estriol da estradiol ba iri daya bane. Estriol shine yanayin rashin ƙarfi na estrogen wanda kawai za'a iya samun sa a cikin kayan haɗin maganin haɗin hormone. Estradiol ya fi ƙarfi fiye da estriol kuma an yarda da FDA don maganin maye gurbin hormone.

Shin estriol ko estradiol sun fi kyau?

Estradiol ya fi ƙarfi da tasiri fiye da estriol. Estriol shine yanayin rashin ƙarfi na estrogen kuma yana iya samun kyakkyawan yanayin tsaro idan aka kwatanta da estradiol. Koyaya, ana iya buƙatar ƙarin gwaji na asibiti akan tasiri da amincin estriol.

Shin zan iya amfani da estriol ko estradiol yayin da nake da juna biyu?

A'a. Ya kamata a guji estrogens kamar estriol da estradiol yayin da suke da juna biyu. Shan waɗannan magunguna yayin da mai ciki na iya haifar da ƙarin haɗarin haihuwar yara. Kada a sha kwayar estrogen yayin shan nono.

Zan iya amfani da estriol ko estradiol tare da barasa?

A'a. Bai kamata a yi amfani da Estriol ko estradiol da giya ba. Yin amfani da barasa na iya ƙara matakan estrogen a cikin jini. Shan barasa tare da maganin estrogen na iya kara barazanar kamuwa da cutar sankarar mama.