Crestor vs. Lipitor: Bambanci, kamance, kuma wanne ne mafi alheri a gare ku
Magunguna vs. AbokiBayanin magunguna & manyan bambance-bambance | Yanayin da aka bi | Inganci | Inshorar inshora da kwatancen farashi | Sakamakon sakamako | Hadin magunguna | Gargadi | Tambayoyi
A cewar Cibiyoyin Kula da Rigakafin Cututtuka (CDC), game da 38% na manya a Amurka suna da babban cholesterol. Idan kuna da babban cholesterol, likitanku zai iya ba ku shawara kan mahimmancin abinci da motsa jiki. Likitanka na iya ambaci fara magungunan statin. Statins shahararrun magunguna ne, wanda aka fi sani da HMG-CoA reductase inhibitors. Suna aiki ta hanawa enzyme (wanda ake kira HMG-CoA reductase) wanda jikinka yake buƙatar yin cholesterol.
Crestor da Lipitor shahararrun mashahuran suna ne guda biyu wadanda ake amfani dasu don rage matakan cholesterol. Dukkanin magungunan sun sami karbuwa daga Hukumar Abinci da Magunguna ta Amurka (FDA). Ana amfani dasu tare da rage ƙarancin abinci mai ƙoshi da cholesterol don rage cholesterol. Kodayake Crestor da Lipitor dukansu statins ne, basu zama iri ɗaya ba. Ci gaba da karatu don ƙarin koyo game da Crestor da Lipitor.
Menene manyan bambance-bambance tsakanin Crestor da Lipitor?
Crestor (Menene Crestor?) Da Lipitor (Menene Lipitor?) Dukansu magunguna ne masu rage ƙirar. An kuma san su da suna statins, ko HMG-CoA reductase inhibitors. Dukansu magunguna guda biyu ana samun su a cikin sifa da tsari iri ɗaya kuma azaman allunan kawai. AstraZeneca ta ƙera sunan-mai suna Crestor, kuma Pfizer yana sanya Lipitor mai sunan alama. Ana amfani da Crestor da Lipitor a cikin manya; duk da haka, a wasu lokuta, ana iya amfani dasu a cikin yara.
| Babban banbanci tsakanin Crestor da Lipitor | ||
|---|---|---|
| Crestor | Lashin mai | |
| Ajin magani | HMG-CoA reductase mai hanawa (wanda aka fi sani da statin ko wakili mai rage lipid) | HMG-CoA reductase mai hanawa (wanda aka fi sani da statin ko wakili mai rage lipid) |
| Alamar alama / ta kowa | Brand da janar | Brand da janar |
| Menene sunan jimla? | Rosuvastatin | Atorvastatin |
| Wani nau'i (s) ne miyagun ƙwayoyi ya shigo? | Kwamfutar hannu | Kwamfutar hannu |
| Menene daidaitaccen sashi? | Misali: 10 MG kowace rana | Misali: 20 MG kowace rana |
| Yaya tsawon maganin al'ada? | Dogon lokaci | Dogon lokaci |
| Wanene yawanci yake amfani da magani? | Manya; yara 'yan shekaru 7 zuwa sama (a wasu lokuta) | Manya; yara 10 shekarun da suka wuce (a wasu lokuta) |
Yanayin da Crestor da Lipitor suka kula da shi
Ana amfani da Crestor da Lipitor don rage cholesterol. Ya kamata a yi amfani da Crestor ko Lipitor, tare da rage cin abinci mai ƙoshin mai da ƙwanƙolin cholesterol, lokacin da cin abinci shi kaɗai bai yi cikakken aiki ba don rage ƙwayar cholesterol. Crestor da Lipitor ƙananan duka cholesterol, LDL, ApoB, da triglycerides . Suna kuma kara HDL cholesterol, kyakkyawan nau'in kwalastaral.
Sauran alamun suna cikin jadawalin da ke ƙasa. Crestor da Lipitor ba a yi nazarinsu ba game da maganin Fredrickson Type I da V dyslipidemias.
| Yanayi | Crestor | Lashin mai |
| Hyperlipidemia da haɗakar dyslipidemia a cikin manya | Ee | Ee |
| Hypercholesterolemia na Iyali a cikin yara | Ee | Ee |
| Hypertriglyceridemia a cikin manya | Ee | Ee |
| Primary dysbetalipoproteinemia (Nau'in III hyperlipoproteinemia) a cikin manya | Ee | Ee |
| Homozygous dangin hypercholesterolemia a cikin manya | Ee | Ee |
| Raunin atherosclerosis a cikin manya | Ee | Ee |
| Rigakafin cututtukan zuciya (ciwon zuciya, cututtukan zuciya) | Ee | Ee |
Shin Crestor ko Lipitor sun fi tasiri?
Masu bincike sun kwatanta da yawa a cikin gwaji na asibiti da ake kira GASKIYA fitina (Magungunan Statin don Matakan Laƙan Lɓɓuka Idan Aka Kwatanta Duk Abincin zuwa Rosuvastatin). Sun duba tasirin Lipitor, Crestor, Zocor, da Pravachol akan rage LDL (low-density lipoprotein) cholesterol bayan makonni shida.
Binciken ya kammala da cewa Crestor ya saukar da LDL cholesterol da kashi 8.2% fiye da na Lipitor, kuma Crestor ya saukar da yawan cholesterol sosai fiye da duk sauran wuraren da aka yi nazari. Har ila yau Crestor ya ƙara yawan cholesterol na HDL (mai kyau irin na cholesterol) fiye da yadda Lipitor yayi. A cikin marasa lafiyar da suka ɗauki Crestor, ya danganta da kashi, kashi 82-89% sun cimma burin LDL cholesterol, idan aka kwatanta da kashi 69-85% na marasa lafiyar da suka ɗauki Lipitor. Dukkanin yanayin an daidaita su kamar haka.
Wani binciken da ake kira SATURN fitina (Nazarin Atheroma na Coronary atheroma ta Intravascular Ultrasound: Tasirin Rosuvastatin a kan Atorvastatin) ya kalli manyan allurai na Crestor-40 mg kowace rana da kuma Lipitor 80 mg kowace rana-da kuma tasirinsu kan ci gaban jijiyoyin zuciya na atherosclerosis. Cutar jijiyoyin jiki ita ce taƙaita hanyoyin jijiyoyin jini da kuma gina ƙwayoyin alli da na mai a cikin jijiyoyin, wanda ke sa wuya jini ya isa ga zuciya, da ƙara haɗarin kamuwa da cututtukan zuciya.
Binciken ya kuma duba lafiya da illolin. Bayan shekaru biyu na iyakar allurai, ƙungiyar Crestor tana da ƙananan matakan LDL kuma ƙananan matakan HDL fiye da na Lipitor. (Kodayake, yana iya zama abin lura cewa AstraZeneca, mai kera Crestor, ya ba da kuɗin wannan binciken. Hakanan, an ba da waɗannan magungunan a mafi girman allurai, waɗanda ba su da yawa a yanayin asibiti ga matsakaicin mai haƙuri.) Dukansu Crestor da Lipitor sun jawo koma baya na atherosclerosis zuwa irin wannan har. Dukansu magungunan sun sami juriya sosai kuma suna da ƙananan abubuwan rashin lahani.
A cikin yanayin asibiti, an ba da magungunan biyu ko'ina kuma an jure su sosai. Magunguna mafi mahimmanci a gare ku za'a iya ƙayyade ta hanyar mai ba da sabis na kiwon lafiya, wanda zai iya yin la'akari da yanayin lafiyar ku, tarihin ku, da magungunan da kuka sha waɗanda zasu iya hulɗa da Crestor ko Lipitor.
Verageaukar hoto da kwatancen farashi na Crestor vs. Lipitor
Crestor ko Lipitor suna rufe mafi yawan inshora da tsare-tsaren takardar likita a cikin sifofinsu na rosuvastatin ko atorvastatin. Zaɓin samfurin suna zai iya haifar da ƙarin kuɗi ko kuma ba za a rufe shi ba.
Don takaddun magani na yau da kullun na 30, 10 mg na rosuvastatin (Generic Crestor), farashin aljihun zai kasance kusan $ 134. Kuna iya amfani da coupon kyauta na SingleCare don rage farashin zuwa $ 11 a shagunan sayar da magani.
Takaddun magani na yau da kullun na 30, 20 MG na allurar atorvastatin (mai sanyin Lipitor) zaikai kimanin $ 82 idan ka biya daga aljihu. Kwancen SingleCare na jigilar Lipitor na iya kawo farashin zuwa kusan $ 15.
Yayinda tsare-tsaren suka bambanta kuma zasu iya canzawa, tuntuɓi kamfanin inshorar ku don bayani game da ɗaukar Crestor da Lipitor.
| Crestor | Lashin mai | |
| Yawanci inshora ke rufe shi? | Ee (na asali) | Ee (na asali) |
| Yawanci an rufe shi ta Medicare Part D? | Ee (na asali) | Ee (na asali) |
| Yawan | Misali: 30, 10 mg Allunan | Misali: 30, 20 MG Allunan |
| Hanyar biyan kuɗaɗe na Medicare | $ 0- $ 20 | $ 0- $ 15 |
| SingleCare kudin | $ 11 + | $ 15 + |
Nemi katin rangwame na SingleCare
Illolin gama gari na Crestor vs. Lipitor
Abubuwan da suka fi dacewa na Crestor sune ciwon kai, ciwon tsoka, ciwon ciki, tashin zuciya, da rauni.
Labaran da suka fi lalacewar lebe shine cututtukan sanyi na yau da kullun, ciwon gaɓoɓi, gudawa, jin zafi a ƙasan jiki, da cututtukan fitsari.
Wani mawuyacin tasiri amma mai tsanani na Crestor da Lipitor shine myopathy (rauni na tsoka) da rhabdomyolysis (lalacewar tsoka, wanda zai iya zama mai lahani sosai). Duba sashin gargadi don karin bayani.
Abin da ke faruwa na illa na iya bambanta da sashi. Wannan ba cikakken lissafin sakamako bane. Sauran, mawuyacin illa na iya faruwa. Yi magana da mai baka kiwon lafiya game da irin illar da zaka yi tsammani daga Crestor ko Lipitor, da yadda zaka magance su.
| Crestor | Lashin mai | |||
| Sakamakon sakamako | Ana amfani? | Mitar lokaci | Ana amfani? | Mitar lokaci |
| Ciwon kai | Ee | 5.5% | Ba | - |
| Ciwan | Ee | 3.4% | Ee | 4% |
| Muscle ciwo / zafi | Ee | 2.8% | Ee | 3.8% |
| Hadin gwiwa | Ee | Ya bambanta | Ee | 6.9% |
| Jin zafi a cikin tsauraran matakai | Ba | - | Ee | 6% |
| Cutar fitsari | Ba | - | Ee | 5.7% |
| Rashin ƙarfi | Ee | 2.7% | Ee | 6.9% |
| Rashin narkewar abinci | Ba | - | Ee | 4.7% |
| Maƙarƙashiya | Ee | 2.4% | Ba | - |
| Gudawa | Ba | - | Ee | 6.8% |
| Ciwon ciki | Ee | ≥2% | Ee | % ba a ruwaito ba |
| Ciwon sanyi | Ba | - | Ee | 8.3% |
Source: DailyMed ( Crestor ,, DailyMed ( Lashin mai )
Magungunan ƙwayoyi na Crestor vs. Lipitor
Wani mahimmin abu da ya kamata a sani game da Lipitor shi ne cewa bai kamata ku sha ƙari mai yawa na ruwan 'ya'yan inabi (fiye da lita 1.2 a kowace rana). Yawan ruwan inabi da yawa na iya kara yawan matakan Liba a jikinka, hakan zai sa ka iya fuskantar myopathy (raunin tsoka) da rhabdomyolysis (fashewar tsoka, wanda ka iya zama mai lahani sosai).
Wadannan matsalolin tsoka suna iya faruwa tare da yawan shan ruwan 'ya'yan inabi, amma yana iya faruwa da karancin yawa. Idan ka ci 'ya'yan inabi ko shan ruwan' ya'yan inabi kuma ka sha Lipitor, ka tambayi likitanka nawa ne lafiyayyen amfani da shi, ko kuwa zai fi kyau ka sha wani magani daban wanda ba zai yi hulɗa da 'ya'yan inabi ba. Crestor bashi da ma'amalar ruwan inabi.
Crestor da Lipitor suna da wasu ma'amaloli masu amfani da kwayoyi iri ɗaya, misali, tare da cyclosporine, gemfibrozil, niacin, fenofibrate, colchicine, da wasu magungunan ƙwayoyin cuta da ake amfani da su don HIV. Hada Crestor ko Lipitor tare da ɗayan waɗannan ƙwayoyi na iya ƙara matakan statin, wanda ke haifar da haɗarin kamuwa da ciwon zuciya da kuma rhabdomyolysis. Dogaro da haɗuwa da ƙwayoyi da tarihin lafiyar ku / yanayin ku, likitan ku na iya buƙatar daidaita sashin magungunan ku ko zaɓi madadin magani.
Kafin shan Crestor ko Lipitor, gaya wa likitanka game da duk magungunan da ka sha, ciki har da takardar sayan magani, kan-kan-kan-kan (OTC), da bitamin, don haka za su iya tantance ko Crestor ko Lipitor suna da lafiya a gare ku.
| Drug | Ajin magani | Crestor | Lashin mai |
| Cyclosporine | Immunosuppressant | Ee | Ee |
| Gemfibrozil | Magani ga babban triglycerides | Ee | Ee |
| Wasu magungunan cutar kanjamau | Magungunan HIV masu cutar kanjamau | Ee | Ee |
| Itraconazole | Azole antifungal | Ba | Ee |
| Clarithromycin | Kwayar maganin rigakafi ta Macrolide | Ba | Ee |
| Darolutamide | Masu hana karɓar mai karɓar haraji na ciwon asrogen | Ee | Ba |
| Regorafenib | Kinase mai hana cutar kansa | Ee | Ba |
| Warfarin | Anticoagulant | Ee | Ba |
| Niacin | Wakilin rigakafin cutar | Ee | Ee |
| Fenofibrate | Wakilin rigakafin cutar | Ee | Ee |
| Colchicine | Anti-dandano wakili | Ee | Ee |
| Maalox Mylanta Ayyuka | Antacids | Ee | Ba |
| Ruwan inabi | Ruwan inabi | Ba | Ee |
| Rifampin | Antimycobacterial | Ba | Ee |
| Maganin hana haihuwa na baka | Maganin hana haihuwa na baka | Ba | Ee |
| Digoxin | Cardiac glycosides | Ba | Ee |
Gargadi na Crestor da lebe
- A cikin wasu lamura da ba kasafai ake samun su ba, raunin tsoka da lalacewa na iya faruwa saboda shan magani na statin. Wannan na iya faruwa tare da kowane kashi amma ya fi yawa tare da allurai mafi girma. Yi amfani da hankali a cikin marasa lafiya masu shekaru 65 ko sama da haka, marasa lafiya da matsalolin koda, da marasa lafiya da ke da hypothyroidism wanda ba shi da iko. Waɗannan haɗarin kuma suna ƙaruwa idan aka ɗauki wasu magunguna a haɗe tare da Crestor ko Lipitor, kamar fenofibrate, niacin, cyclosporine, colchicine, ko wasu magunguna masu amfani da kwayar cutar HIV. Idan kuna da ciwo na tsoka, ko rauni na tsoka, ko taushi, musamman ma idan kun ji gajiya da / ko kuma zazzabi, ku sanar da likitanku nan da nan. Ya kamata a dakatar da Crestor ko Lipitor idan kun sami ƙaruwa sosai game da haɓakar haɓakar halittar kumburi ko kuma rashin jin daɗin cutar.
- A lokuta da yawa, yanayin da ake kira myopathy necrotizing myopathy (IMNM) na iya faruwa daga maganin statin. Alamomi da alamomi sun haɗa da raunin tsoka da canje-canje a cikin lab.
- Marasa lafiya yakamata suyi gwajin enzyme na hanta kafin fara Crestor ko Lipitor, yayin magani idan akwai wasu alamun matsalolin hanta, da / ko lokacin da likita ya ji ya dace da waɗannan gwajin jini. Magungunan Statin na iya ƙara matakan AST ko ALT. A cikin wasu lokuta mawuyacin hali, gazawar hanta (na mutuwa ko wanda ba mai mutuwa ba) ya faru a cikin marasa lafiya da ke shan statins. Ya kamata a dakatar da Crestor ko Lipitor kai tsaye idan mummunan rauni na hanta ya faru. Idan kana da alamun kasala, rashin ci, fitsari mai duhu, ko raunin fata ko idanu, tuntuɓi likitanka nan da nan.
- Yi amfani da Crestor ko Lipitor tare da taka tsantsan a cikin marasa lafiyar da ke yawan shan giya.
- Yi amfani da Crestor ko Lipitor tare da taka tsantsan a cikin marasa lafiya da tarihin cutar hanta. Mutanen da ke fama da cutar hanta kada su yi amfani da Crestor ko Lipitor.
- Canje-canje a cikin matakan glucose da haemoglobin A1C na iya faruwa daga Crestor ko Lipitor. Haɗarin yana ƙaruwa tare da amfani da ketoconazole, spironolactone, ko cimetidine.
- A wasu lokuta mawuyacin yanayi, asarar ƙwaƙwalwa ko rikicewa na iya faruwa. Tuntuɓi masu sana'a na kiwon lafiya kai tsaye don jagora idan kai ko ƙaunatattunka sun lura da kowane canje-canje.
- Kar a dauki allurai biyu na Crestor ko Lipitor a tsakanin awanni 12 na juna.
- Ana iya ɗaukar Crestor ko Lipitor tare da ko ba tare da abinci ba a kowane lokaci na rana. Swallow kwamfutar hannu duka.
- Kada a taɓa amfani da Crestor ko Lipitor a cikin ciki saboda haɗarin cutarwar tayi. Kar a shayar da mama yayin shan Crestor ko Lipitor.
Wararin gargaɗin Crestor:
- Marasa lafiya da ke shan maganin hana yaduwar jini (kamar warfarin) ya kamata a sanya musu ido sosai kafin su ɗauki Crestor, kuma akai-akai a farkon aikin maganin, don tabbatar da INR ya kasance cikin kwanciyar hankali.
- Marasa lafiya da ke shan antacid mai ɗauke da aluminium da magnesium ya kamata su sha maganin a ƙalla awanni biyu bayan shan Crestor.
Wararin gargaɗin Lipitor:
- Amfani da ruwan 'ya'yan inabi da / ko ruwan inabi (fiye da lita 1.2 a kowace rana) haɗe tare da Lipitor na iya ƙara yawan ɓarna da haɗarin rhabdomyolysis.
Tambayoyi akai-akai game da Crestor vs. Lipitor
Menene Crestor?
Crestor sigar statin ce, ko HMG-CoA reductase mai hanawa, wanda aka saba amfani dashi don magance babban cholesterol. Sunan sa na gaba shine rosuvastatin. Akwai wadatar Crestor a duka nau'ikan alamu iri iri kuma azaman kwamfutar hannu.
Menene Lipitor?
Lipitor, kamar Crestor, magani ne wanda yake amfani da ƙwayar cholesterol. Sunan sa na gaba shine atorvastatin. Akwai shi a cikin kwamfutar hannu, a duka iri da janar.
Shin Crestor da Lipitor iri ɗaya ne?
Crestor da Lipitor duka statins ne. Suna aiki iri ɗaya kuma suna da kamanceceniya. Koyaya, ba daidai suke ba. Kuna iya karantawa game da bambance-bambance a cikin bayanin da aka zayyana a sama. Sauran yanayin da wataƙila kun ji labarin sun haɗa da Pravachol (pravastatin), Zocor (simvastatin), Livalo (pitavastatin), Lescol (fluvastatin), da Mevacor (lovastatin).
Shin Crestor ko Lipitor sun fi kyau?
Karatuttuna na nuna dukkanin kwayoyi sunada tasiri wajan rage cholesterol (duba sashen da ke sama). Wasu nazarin suna nuna Crestor ya zama mai ɗan tasiri kaɗan; duk da haka, duka magungunan suna da inganci kuma an haƙura dasu sosai. Tambayi mai ba da lafiyar ku idan ɗayan waɗannan magungunan za su fi dacewa da ku, gwargwadon tarihin lafiyar ku.
Zan iya amfani da Crestor ko Lipitor yayin da nake da juna biyu?
A'a. Crestor ko Lipitor bai kamata mace mai ciki ta ɗauka ba. Dukkanin magungunan an hana su musamman don amfani yayin daukar ciki. Suna iya haifar da lahani ga jaririn da ba a haifa ba. Idan kana shan Crestor ko Lipitor kuma sun gano cewa kana da juna biyu, to ka daina shan maganin kuma ka tuntuɓi likitanka nan da nan don shawarar likita.
Zan iya amfani da Crestor ko Lipitor tare da barasa?
Gabaɗaya, yana da lafiya a cinye a ƙaramar matsakaiciyar giya idan ka dauki Crestor ko Lipitor. Koyaya, idan kuna da matsalolin hanta, ko kuma shan giya mai yawa, bincika likitan lafiyar ku kafin haɗuwa da statin da giya. Mutanen da ke da cutar hanta na yau da kullun ya kamata su guji shan barasa gaba ɗaya yayin shan wani abu.
Shin Crestor ya fi Laftari aminci?
Crestor da Lipitor dukansu masu haƙuri ne. Duk wani magani yana da tasiri, tare da wasu mawuyacin tasiri amma masu tasiri, suma. Nazarin (duba ɓangaren da ke sama) ya nuna cewa an yarda da magungunan duka sosai a cikin gwaji.
Waɗanne abinci ya kamata a guji yayin shan Crestor?
Lokacin da kuka ɗauki Crestor (ko Lipitor), ya kamata ku ci abinci mai ƙoshin lafiya mai ƙoshin kitse mai ƙyama da mai ƙwai.
Wasu abincin da za ku so ku guji sune nama mai ƙiba, kiwo mai cikakken mai, da kayan zaki. Madadin haka, mai da hankali kan abinci kamar 'ya'yan itace, kayan marmari, hatsi cikakke, wake, kwayoyi, da furotin masu laushi kamar kaza da kifi.
Kodayake Lipitor yana hulɗa da (yawancin) ruwan 'ya'yan inabi, Crestor yana da lafiya a ɗauka tare da ruwan' ya'yan inabi.
Shin Crestor yana sa ku ƙara nauyi?
Crestor ba shi da alaƙa kai tsaye da ƙimar nauyi. Idan kuna shan Crestor kuma kun lura da canjin nauyi, tuntuɓi mai ba da lafiyar ku.
