Main >> Magunguna Vs. Aboki >> Boniva vs. Fosamax: Bambanci, kamanceceniya, kuma wanene yafi muku alheri

Boniva vs. Fosamax: Bambanci, kamanceceniya, kuma wanene yafi muku alheri

Magunguna vs. Aboki

Boniva da Fosamax wasu magunguna ne guda biyu da ake amfani da su wajen maganin cutar sanyin kashi. Osteoporosis cuta ce ta kasusuwa. Yana faruwa ne lokacin da adadin ma'adinai na kashi ko yawan kashi yake raguwa, ko lokacin da ingancin kashin ya lalace. Lokacin da ingancin kashi yake raguwa, mutane na cikin kasadar kasusuwa, ko karye kasusuwa. Wadannan karayar na iya hadawa da karaya ta hanji, kashin baya, da kuma karaya ga kashin mata da cinya.

Akwai abubuwa da yawa da zasu rage yuwuwar kamuwa da cutar kashin baya. Waɗannan sun haɗa da motsa jiki da motsa jiki a kai a kai, rage shan giya, guje wa shan taba, da cin abinci mai cike da bitamin D da alli. Idan likitanku ya tabbatar kuna buƙatar magani don maganin osteoporosis, za su iya zaɓar Boniva da Fosamax, waɗanda ke cikin rukunin magungunan da ake kira bisphosphonates. Akwai wasu zaɓuɓɓukan magani don osteoporosis, waɗanda suka haɗa da Evista (raloxifene), Forteo (Tsarin), Prolia (denosumab), calcitonin, da kuma maganin estrogen.

Menene manyan bambance-bambance tsakanin Boniva da Fosamax?

Boniva (ibandronate) magani ne na likita wanda aka rarraba azaman bisphosphonate. Bisphosphonates suna aiki ta hana hanawar kashi kashi na osteoclast. Basu hana samuwar kashi. Tsarin bisphosphonates na ƙarni na biyu, kamar Fosamax, sun fi ƙarfin hanawa na osteoclasts fiye da na ƙarni na farko, kamar Didronel (etidronate). Sauran bisphosphonates na ƙarni na biyu sun haɗa da Actonel (risedronate), Fosamax (alendronate), Aredia (pamidronate), da kuma Maimaitawa (acid zoledronic). Boniva yana samuwa a cikin ƙarami mai ƙarfi na 150 mg. Ana daukar Boniva a cikin ta baka sau ɗaya kowane wata. Boniva shima ana samun shi azaman maganin allura a cikin girman 3 mg / 3 ml.

Fosamax (alendronate) magani ne na likitanci wanda kuma shine ƙarni na biyu bisphosphonate. Fosamax yana samuwa a cikin allunan baka cikin ƙarfin 5 MG, 10 mg, 35 mg, da 70 mg. Hakanan ana samun shi a cikin maganin baka 70 mg / 75 ml. Magungunan 5 MG da 10 MG suna nufin zama sau ɗaya-kowace rana. 35 MG da 70 MG sau ɗaya ne a kowane mako.

Babban bambanci tsakanin Boniva da Fosamax
	Boniva	Fosamax
Ajin magani	Bisphosphonates	Bisphosphonates
Alamar alama / ta kowa	Nau'i da janar akwai	Nau'i da janar akwai
Menene sunan gama-gari?	Ibandronate	Alendronate
Wani nau'i (s) ne miyagun ƙwayoyi ya shigo?	Allunan baka da magani don allura	Allunan na baka da maganin baka
Menene daidaitaccen sashi?	150 MG sau ɗaya a wata	70 MG sau ɗaya a mako
Yaya tsawon maganin al'ada?	Dogon lokaci	Dogon lokaci
Wanene yawanci yake amfani da magani?	Manya	Manya

Yanayin da Boniva da Fosamax suka kula da shi

Ana amfani da Boniva da Fosamax a duka magani da kuma rigakafin cutar sanyin kashi. Don Fosamax, wannan ya hada da postmenopausal da corticosteroid-induced osteoporosis. An yarda da Boniva don amfani a cikin aikin bayan ango, amma amfani da shi a cikin corticosteroid wanda ya haifar da osteoporosis ba shi da lakabi. Alamar kashewa tana nufin amfani da magani don alamar da Hukumar Abinci da Magunguna (FDA) ba ta amince da shi ba. An kuma yarda da Fosamax wajen maganin cutar Paget, yanayin da kasusuwa ke girma da rauni fiye da al'ada. Hakanan ana amfani da Boniva don wannan dalilin kashe-lakabin.

Yanayi	Boniva	Fosamax
Postmenopausal magani osteoporosis	Ee	Ee
Corticosteroid-jawo osteoporosis magani	Kashe-lakabi	Ee
Postmenopausal osteoporosis prophylaxis	Ee	Ee
Corticosteroid-haifar da osteoporosis prophylaxis	Kashe-lakabi	Ee
Cutar Paget	Kashe-lakabi	Ee
Hypercalcemia na malignancy	Kashe-lakabi	Kashe-lakabi
Abubuwa masu banƙyama na kasusuwa saboda ƙananan ƙashi	Kashe-lakabi	Ba

Shin Boniva ko Fosamax sun fi tasiri?

Maganin Biki na Watanni Tare da Ibandronate Don Nazarin Rigakafin Rigakafin Osteoporosis, in ba haka ba ana kiransa da GWADA motsi . Sakamakon ya nuna cewa sau ɗaya a kowane wata Boniva baya ƙasa da Fosamax dangane da wannan ƙarshen. Raguwa cikin jujjuyawar kashi da haƙurin ciki sun kasance daidai.

Gwajin Boniva Alendronate a cikin Osteoporosis, ko Gwajin BALTO , kimanta fifikon marasa lafiya tsakanin Fosamax sau ɗaya a mako da Boniva sau ɗaya. Sakamakon wannan bazuwar, gwajin gwaji ya gano cewa mafi yawan marasa lafiya sun fi son tsarin wata-wata, tare da 66.1% sun fi son Boniva idan aka kwatanta da 26.5% da suka fi son Fosamax. Ragowar bai nuna fifikon tsarin daya akan dayan ba.

Ba a nufin wannan bayanin ya zama likita. Kwararren likitan ku kawai zai iya ƙayyade wane zaɓi na magani ya fi dacewa da yanayin ku.

Verageaukar hoto da kwatancen kuɗi na Boniva vs. Fosamax

Boniva magani ne na likitanci wanda yawanci ana rufe shi ne ta hanyar inshorar kasuwanci da kuma shirin inshora. Ba tare da inshora ba, tsarin mulkin wata-wata na iya cin kuɗin $ 258 na kwamfutar hannu ɗaya. Tare da coupon daga SingleCare, farashin Boniva zai iya zama ƙasa da $ 22.

Fosamax magani ne na likitanci wanda aka rufe shi ta hanyar inshorar kasuwanci da ta inshora. Isar da Fosamax na wata ɗaya na iya biyan ku kusan $ 102 ba tare da inshora ba. Takaddun shaida na SingleCare don jigilar Fosamax na iya rage farashin zuwa ƙasa da $ 20.

	Boniva	Fosamax
Yawanci inshora ya rufe?	Ee	Ee
Yawanci an rufe shi ta Medicare Part D?	Ee	Ee
Yawan	1, 150 mg kwamfutar hannu	4, allunan mg 70
Hanyar biyan kuɗaɗe na Medicare	<$10	<$10
SingleCare kudin	$ 22- $ 98	$ 16- $ 39

Illolin gama gari na Boniva vs. Fosamax

Bisphosphonates sananne ne saboda halin su na haifar da illa ga ciki kamar ciwon ciki, tashin zuciya, zawo, da maƙarƙashiya. Marasa lafiya waɗanda ke da tarihin cututtukan ciki ba za su iya zama 'yan takara don maganin bisphosphonate ba saboda suna cikin haɗarin fuskantar waɗannan tasirin yayin da suke kan ilimin bisphosphonate. Wadannan halayen wasu lokuta suna da tsananin isa don buƙatar asibiti.

Fosamax da Boniva duka sanannu ne don haifar da ciwon musculoskeletal a cikin ƙasusuwa, tsokoki, da haɗin gwiwa.

Boniva an nuna yana da alaƙa da ƙaruwar hawan jini da rashin bacci, ko wahalar bacci.

Shafin da ke zuwa ba yana nufin jerin abubuwan da zasu iya faruwa wadanda suka shafi Fosamax da Boniva ba. Da fatan za a tuntuɓi mai ba ku kiwon lafiya don cikakken jeri.

	Fosamax	Boniva
Sakamakon sakamako	Ana amfani?	Mitar lokaci	Ana amfani?	Mitar lokaci
Ciwon ciki	Ee	6.6%	Ee	7.8%
Ciwan	Ee	3.6%	Ee	5,1%
Dyspepsia	Ee	3.6%	Ee	5.6%
Maƙarƙashiya	Ee	3.1%	Ee	4.0%
Gudawa	Ee	3.1%	Ee	5,1%
Ciwan ciki	Ee	2.6%	Ba	N / A
Acid regurgitation	Ee	2.0%	Ba	N / A
Ciwon ciki	Ee	1.5%	Ba	N / A
Amai	Ee	1.0%	Ba	N / A
Dysphagia	Ee	1.0%	Ba	N / A
Cushewar ciki	Ee	1.0%	Ba	N / A
Gastritis	Ee	0.5%	Ee	kashi biyu
Ciwon tsoka	Ee	4.1%	Ee	4.5%
Ciwon kai	Ee	2.6%	Ba	N / A
Ku ɗanɗani karkatarwa	Ee	0.5%	Ba	N / A
Hawan jini	Ba	N / A	Ee	6.3%
Myalgia	Ba	N / A	Ee	2.0%
Rash	Ba	N / A	Ee	2.3%
Rashin bacci	Ba	N / A	Ee	2.0%

Source: Fosamax ( DailyMed ) Boniva ( DailyMed )

Magungunan ƙwayoyi na Boniva vs. Fosamax

Lokacin da aka ba Boniva da Fosamax tare da alli dauke da kari ko antacids, alli na iya tsoma baki tare da shawar Fosamax. Mutane da yawa marasa lafiya na osteoporosis suna buƙatar ɗaukar ƙwayar alli, sabili da haka ana ba da shawarar cewa ku jira mafi ƙarancin minti 30 bayan shan Fosamax don shan alli ko wasu magunguna na baka.

Magungunan anti-inflammatory marasa ƙwayar cuta (NSAIDs) suna haɗuwa da kansu tare da sakamako masu illa na ciki kamar bisphosphonates. Ba'a ba da shawarar ɗaukar daidaito na NSAID yayin shan bisphosphonates ba.

Akwai wasu shaidu da ke nuna cewa bada bisphosphonates tare da masu hana H2, wani nau'i ne na masu rage sinadarin acid a ciki wanda ake amfani da shi don magance zafin ciki, yana kara samar da kwayar bisphosphonate.

Wannan jadawalin ba ya lissafta kowane sanannen hulɗar magunguna. Da fatan za a tuntuɓi masu sana'a na kiwon lafiya don cikakken jerin.

Drug	Ajin magani	Fosamax	Boniva
Alli Aluminium Magnesium Ironarfe	Abubuwan haɗin cation da yawa da maganin kashe kumburi	Ee	Ee
Asfirin Ibuprofen Naproxen Diclofenac Ketorolac Meloxicam Celecoxib	Magungunan rigakafin cututtukan ƙwayoyin cuta (NSAIDS)	Ee	Ee
Famotidine Ranitidine	H2-masu toshewa	Ee	Ee

Gargadi na Boniva da Fosamax

Haɗin haƙori yayin da ake amfani da maganin bisphosphonate na iya ƙara haɗarin ɓarkewar ciwon sankarar ƙashi na muƙamuƙi (ONJ), ko kuma mutuwar ƙashin kasusuwa a hankali. Kafin fara maganin bisphosphonate, marasa lafiya yakamata suyi gwajin hakori kuma suyi la'akari da yin duk wata hanyar kariya ko gyara hakori kafin fara maganin.

Marasa lafiya waɗanda ke da yanayin yanayin abinci na yau da kullun kamar su Barrett's esophagus, dysphagia, ko ulcers na iya samun yanayin su ya ƙara ta da bisphosphonates. Saboda yanayin da suke da shi na haifar da da damuwa ga mucosa na esophagus, ya kamata a ɗauki bisphosphonates abu na farko da safe tare da ƙaramin gilashin ruwa. Sauran magunguna, abubuwan sha, da abinci ya kamata a guji don aƙalla aƙalla mintuna 30, amma da kyau don awanni biyu. Marasa lafiya ya kamata su kasance a tsaye na aƙalla aƙalla mintuna 30 bayan shan maganinsu. Bai kamata su kwanta ba. Wadannan abubuwan kiyayewa zasu rage fushin esophageal.

Marasa lafiya waɗanda ke da ƙananan ƙwayoyin alli, ko hypocalcemia, ya kamata su ɗauki matakan da suka dace don daidaita matakan allurar su kafin fara maganin bisphosphonate. Marasa lafiya na iya ci gaba da maganin allurar ƙwayoyin cuta da zarar sun fara bisphosphonates muddin sun bi jagororin don raba alli daga sinadarin bisphosphonate.

Ya kamata a yi amfani da Fosamax da Boniva tare da taka tsantsan a cikin marasa lafiyar da ke fama da larurar koda ko cutar koda. Ya kamata a kula da aikin koda saboda rage aikin koda yana nufin ba za ku iya kawar da maganin daga jikinku ba yadda ya kamata kuma maganin zai iya tarawa cikin jikinku.

Tambayoyi akai-akai game da Boniva vs. Fosamax

Menene Boniva?

Boniva magani ne na likita a cikin aji da ake kira bisphosphonates. Ana amfani da shi don magancewa da hana cutar sanyin ƙashi. Boniva yana samuwa azaman maganin cikin jini kamar na kwaya daya na baka na wata-wata.

Menene Fosamax?

Fosamax kuma magani ne na likitanci a ajin magungunan da ake kira bisphosphonates. Ana amfani dashi wajen magani da rigakafin cutar sanyin kashi. Ana samun Fosamax a cikin leda na baka sau daya a rana, sau daya a kowane mako na maganin baki, da kuma maganin baka.

Shin Boniva da Fosamax iri daya ne?

Boniva da Fosamax sune bisphosphonates na ƙarni na biyu, amma ba daidai suke ba. Babban banbancin su shine yadda ake musu. Ana iya bayar da Boniva sau ɗaya a kowane wata, yayin da Fosamax za a iya bayar da shi sau ɗaya a rana ko kuma sau ɗaya a mako.

Shin Boniva ko Fosamax sun fi kyau?

Nazarin ya nuna Boniva da Fosamax suna da sakamako irin na asibiti game da lafiyar ƙashi, amma, aƙalla binciken daya ya nuna cewa yawancin marasa lafiya sun fi son tsarin maganin Boniva sau ɗaya a wata.

Shin zan iya amfani da Boniva ko Fosamax yayin da nake da juna biyu?

Babu Boniva ko Fosamax da aka yi karatu a cikin mata masu ciki. Ya kamata a guji amfani da su a cikin mata masu ciki don guje wa cutar da tayin.

Zan iya amfani da Boniva ko Fosamax da barasa?

Ya kamata a guje wa barasa da duk wani abu na ruwa na wani lokaci bayan shan Boniva ko Fosamax don guje wa ɓacin rai. Amfani da giya mai dacewa yana haɗuwa da haɗarin kasusuwa na osteoporosis, sabili da haka yana da kyau a ƙayyade amfani.

Menene mafi kyawu kuma mafi amincin magani don osteoporosis?

Da Gidauniyar Osteoporosis ta Kasa yana ba da jagororin don maganin osteoporosis. Bisphosphonates kamar Fosamax, Boniva, Reclast, da kuma Actonel ana daukar su magani na farko-layi tare da wasu shawarwari irin su karin alli da motsa jiki.

Shin Boniva yana ƙaruwa da ƙashi?

Boniva yana haɗuwa da haɓaka mai mahimmanci a cikin ƙimar ma'adinai na ƙashi (BMD). Wannan yana rage haɗarin karaya a cikin marasa lafiyar osteoporosis.

Shin ya kamata ku sha alli tare da Boniva?

Bai kamata ku sha alli a lokaci ɗaya da Boniva ba, amma za ku iya shan alli don asarar kashi yayin da ake kan maganin Boniva. Dole ne ku jira aƙalla mintuna 30 bayan yawan bisphosphonate ɗinku kafin shan ƙarin ƙwayoyin ku.