Menene mafi kyawun beta toshewar zuciya?
Bayanin MagungunaMasu gwajin Beta an gwada su sosai kuma suna amfani da magunguna. Masu ba da kiwon lafiya suna ba da umarnin su tun 1970s . Masu hana Beta suna da izinin FDA don magance komai daga glaucoma zuwa ƙaura. Amma, ana amfani da su don maganin yanayin zuciya da jijiyoyin jini-sau da yawa azaman magani na farko don rashin cin nasara zuciya.
Ta yaya masu hana beta ke aiki?
Masu hana Beta suna aiki ta hanyar iyakance illar epinephrine (wanda aka fi sani da adrenaline) - hormone damuwa. Wannan yana rage bugun zuciyar ka, yana rage hawan jini, kuma yana bude hanyoyin jini don inganta gudan jini. Wadannan magunguna na iya magance cutar hawan jini (hauhawar jini), bugun zuciya mara kyau (arrhythmia), ciwon kirji, zuciya rashin cin nasara, ƙaura, da bugun zuciya.
Ga marasa lafiya da ke fama da ciwon zuciya, masu hana beta yawanci suna aiki [don rage damuwa a kan zuciya] ta hanyar rage bugun zuciyar mara lafiya, ya bayyana Dawn Shill , Pharm.D., Kimiyyar harhada magunguna na Veteran’s Affairs Healthcare System a Anchorage, Alaska.
Masu toshe Beta suna taimakawa wajen haɓaka daidaiton wadataccen ƙwayar cuta da buƙata. Dr. Shill ya ce, Ainihi, wani lokacin gazawar zuciya na da matsala. Ma'ana, akwai raunin jijiyoyin tsoka a cikin zuciya wanda ke haifar da ragin adadin jini da aka zubo daga zuciya. Masu toshe Beta na iya taimakawa inganta aiki a wasu yankuna na zuciya ta rage adadin iskar oxygen da ake buƙata don zuciya ta yi aiki a matakin da ya dace.
Bincike Hakanan yana nuna cewa masu hana beta sun rage sakin norepinephrine. Tare da epinephrine, norepinephrine yakan ɗaura ga masu karɓa a ko'ina cikin jiki kuma yana haɗuwa da hawan jini da bugun zuciya. Toshe ɗaurin waɗannan ƙwayoyin cutar zuwa ga masu karɓar su yana taimakawa rage bugun zuciya da hawan jini.
Waɗanne masu hana beta za a iya amfani dasu don ciwon zuciya?
BAna ba masu toshewar eta galibi ga marasa lafiya da ke fuskantar bugun zuciya tare da manufar kasancewa don hana bugun zuciya na biyu daga faruwa.
Da Kwalejin Kasuwancin Amurka musamman yana ba da shawarar masu hana beta masu zuwa, waɗanda aka yarda da FDA don gazawar zuciya:
- Coreg (sassaka)
- Toprol XL (metoprolol succinate)
- Zebeta (bisoprolol)
Yana da mahimmanci a lura cewa kawai ƙaddamar da saki na metoprolol (metoprolol mai amfani da succinate) FDA ta amince da shi don rashin zuciya, ba metoprolol tartrate .
Lokacin amfani da waɗannan masu togacewar beta don maganin gazawar zuciya, suna hana zafin zuciya wuce gona da iri sau da yawa, yayi bayani Jason Reed , Pharm.D.
Har ila yau, yawancin masu hana beta sun rage yadda narkar da zuciyar zuciya take, Dr. Reed yayi bayani. Amma waɗannan masu hana beta ba sa yin hakan, shi ya sa suke iya magance cutar ba tare da ƙara bayyanar cututtuka ba.
A cikin sharuddan bambance-bambance tsakanin masu hana beta amfani da zuciya, ya ce,carvedilol yana toshe masu karɓar beta-1 beta-2 a cikin zuciya, haka kuma masu karɓar alpha-1 a cikin jijiyoyin jini. Metoprolol da bisoprolol da farko sun toshe masu karɓar beta-1 a cikin zuciya. Kodayake waɗannan masu hana beta suna da wasu bambance-bambance, suna da tasiri wajen kare zuciya da rage haɗarin matsaloli daga gazawar zuciya.
| Mafi kyawun masu toshe beta don gazawar zuciya | |||||
|---|---|---|---|---|---|
| Sunan suna (Suna na gama gari) | Sashi | Inganci (idan aka kwatanta da placebo) | Sakamakon sakamako | Learnara koyo | Samo coupon |
| Coreg (sassaka) | 3.125 MG sau biyu a kowace rana don makonni 2, sannan biyo baya ya karu kowane sati 2 har sai an sami sakamako mai so. Matsakaicin 25 MG sau biyu a rana don marasa lafiya masu nauyin ƙasa da kilogiram 85 da 50 MG sau biyu a rana don marasa lafiya masu nauyin fiye da 85 kg. | 65% rage haɗarin mace-mace | Dizziness , kasala, ciwon kai, karin kiba, gudawa | Learnara koyo | Samo coupon |
| Toprol XL (metoprolol succinate) | 12.5 zuwa 25 MG sau ɗaya a rana don makonni 2, sannan ya ƙaru kowane mako 2 har sai an sami sakamako mai so. Matsakaicin 200 MG kowace rana. | 3. 4% rage haɗarin mace-mace | Dizziness , bacin rai, kasala, kumburin ciki, gudawa | Learnara koyo | Samo coupon |
| Zebeta (bisoprolol) | 1.25 MG sau ɗaya a rana don kwanaki 2, sannan 2.5 MG sau ɗaya a rana don watan farko, sannan 5 MG sau ɗaya a rana. Matsakaicin 10 MG kowace rana. | 3. 4% rage haɗarin mace-mace | Ciwon kai , jiri, ciwon mara, gudawa, kasala | Learnara koyo | Samo coupon |
Wanne magani ne aka umurce ku na iya dogara da tsananin ciwon zuciya da kuke fama da shi. Hakanan likitanku zaiyi la'akari da duk wani maganin da kuka gwada da duk wani tasirin da kuka taɓa fuskanta a baya. Misali, bisoprolol yana aiki kamar sauran beta toshiyar zuciya, amma yana iya haifar kasa gajiya fiye da waɗanda ba zaɓaɓɓun beta masu hanawa kamar carvedilol.
Yaushe (da yaya) aka tsara masu tofin beta
Masu hana Beta ba sa ƙarfafa zuciya, kawai suna dakatar da tsarin mai juyayi daga wuce gona da iri.Wannan yana hana tsokar zuciya yin aiki fiye da kima ga cutar hawan jini saboda tsananin zafin nama, wanda zai iya haifar da cututtukan zuciya, Dr. Reed ya bayyana.
Yayinda masu hana beta zasu iya rage lalacewar zuciya ta hanyar cire damuwa, Dr. Shill ya bayyana cewa idan aka ɗauke su ba daidai ba zasu iya raunana zuciya a zahiri. Lokacin da ba'a ɗauka kamar yadda aka tsara ba, zasu iya cutar da fiye da kyau.Masu toshe Beta na iya haifar da ƙananan bugun zuciya mai haɗari da ake kira bradycardia wanda zai iya haifar da ƙarancin hawan jini.Wannan na iya haifar da alamomi kamar jiri, jiri, suma, rashin natsuwa, ko hangen nesa.
Don haka muddin mai haƙuri ya kasance mai karko kuma an tsara mai hana beta daidai a madaidaicin kashi, ana iya amfani da masu hana beta don magance gazawar zuciya. Tsarin juyayi mai juyayi yana wuce gona da iri kuma yana sanya damuwa a zuciya kuma wannan shine dalilin da yasa za'a fara masu hana beta sannan a ci gaba, in ji Dokta Reed. Bayan faɗuwar mummunan rauni na zuciya, yawancin marasa lafiya za su ci gaba da maganin beta toshe maganin. An nuna masu toshe Beta don rage mace-mace, kuma akwai kwararan shaidu da ke tallafawa amfani da su.
Za a iya sanya marasa lafiya ƙaramin maganin beta don rashin nasarar zuciya don farawa. Sannan zasu iya sa ido akan duk wani illa a ƙarƙashin kulawar likita na sati ɗaya ko biyu. Muddin aka jure wa magani da kyau, mai ba da sabis na kiwon lafiya na iya ƙara yawan maganin a hankali har sai an shawo kan alamun, a cewar Dokta Reed.
Wanene ya kamata ba amfani da masu hana beta?
Yayinda masu hana beta zasu iya ceton rai ga wasu marasa lafiya, wannan ba lamari bane ga kowa.Idan mara lafiya yana ciki bugun zuciya tare da wasu yanayi masu rikitarwa kamar COPD, ciwon sukari ko cututtukan jijiyoyin jiki, masu toshe beta ba za su iya zama hanyar da ta dace ba. Ya kamata marasa lafiyar da ke fama da asma da COPD su kiyaye masu toshewar Beta, in ji Dokta Reed. Hakanan ba kyakkyawan ra'ayi bane ga marasa lafiya tare da jinkirin bugun zuciya ko ƙarancin jini.
Kamar dukkanin magunguna, masu hana beta na iya samun illa.
Tsarin jini na bayan gida matsala ce mai wahala ga mutane da yawa tare da masu hana beta, Dr. Reed yayi bayani. Wannan na iya haifar da jiri ko suma.
Wasu beta blockers kuma zasu iya haifar da sakamako masu illa kamar su bakin ciki, gajiya, da kuma raunin kafa, wanda zai iya zama kaɗan daga cikin mawuyacin tasirin tasirin waɗannan magunguna.
Sannan akwai yiwuwar hulɗa da ƙwayoyi don la'akari. Dr. Reed ya ce wasu daga cikin magungunan da aka fi amfani da su wadanda ke mu'amala da masu cutar beta sun hada da NSAIDs da magungunan anti-ulcer.
Baya ga NSAIDs da magungunan anti-ulcer, akwai dogon jerin yiwuwar hulɗa a sani. Marasa lafiya yakamata suyi magana da likitocin su game da lafiyar beta toshe magani idan suna shan ɗayan masu zuwa:
- Hawan jini mai saukar da kwayoyi
- Sauran magungunan zuciya kamar antianginal ko antiarrhythmic drugs
- Magungunan psychotropic kamar antidepressants
- Maganin rigakafi
- Magungunan Statin
- Warfarin
- Magungunan ciwon suga
- Wasu maganin rigakafi kamar Rifampin
A mafi yawan lokuta, masu toshe beta suna magani mai tasiri don gazawar zuciya, yana rage haɗarin mutuwa daga gazawar zuciya, da rage haɗarin sake kamuwa da zuciya. Yi magana da likitanka game da duk wata damuwa da za ka iya samu, kuma ka tabbata ka ba da rahoton duk wata illa da ka samu yayin amfani da beta beta.
