Glipizide vs. metformin: Bambanci, kamanceceniya, kuma wanene yafi muku alheri

Magunguna vs. Aboki

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Glipizide da metformin wasu magunguna ne guda biyu waɗanda ake amfani dasu don magance Ciwon sukari na 2 na mellitus. Mutanen da ke da ciwon sukari Na Biyu suna da matsala tare da hormone insulin, wanda ke da alhakin motsa sukarin jini (glucose) cikin ƙwayoyin jiki don kuzari. Lokacin da insulin baya aiki da kyau, juriya na insulin na iya bunkasa kuma zai haifar da haɓakar glucose, wanda hakan zai haifar da wasu matsalolin lafiya. Glipizide da metformin na iya taimakawa wajen sarrafa matakan glucose mai yawa don rage haɗarin rikitarwa daga ciwon sukari.

Idan aka kwatanta da sababbin wakilai, glipizide da metformin suna da ƙarancin magunguna masu rage yawan ciwon sikari. Dukansu ana amfani dasu don kula da ciwon sukari na Type 2 na dogon lokaci. Kodayake suna da kamanceceniya a cikin tasirin gabaɗaya, glipizide da metformin suna da bambance-bambance da yawa, musamman ma game da yadda suke aiki, illa mai illa, da kuma hulɗar magunguna.

Menene manyan bambance-bambance tsakanin glipizide da metformin?

Glipizide

Glipizide shine sunan gama gari na Glucotrol. Yana daga cikin nau'in magungunan da ake kira sulfonylureas, kuma yana aiki ta hanyar motsa motsawar insulin daga pancreas. Karuwar insulin yana taimakawa rage matakan glucose na jini a jiki.

Akwai sinadarin Glipizide azaman na 5 mg ko 10 mg na roba. Generic glipizide shima ya zo a cikin allunan da aka fadada a cikin karfin 2.5 MG, 5 MG, da kuma 10 MG. Ana shan ruwan gilizide sau ɗaya a rana kafin karin kumallo.

Metformin

Metformin shine asalin sunan Glucophage ko Riomet, kuma yana cikin rukunin magungunan da ake kira biguanides. Metformin yana aiki don magance ciwon sukari na Type 2 ta rage samar da glucose a cikin hanta da rage shayewar glucose a cikin hanjin. Hakanan yana aiki ta haɓaka ƙwarewar insulin da haɓaka ɗaukar glucose a cikin kyallen takarda na jiki.

Metformin yana samuwa azaman kwamfutar hannu ta baka cikin ƙarfin 500 MG, 850 MG, da 1000 MG. Fadada-saki metformin Allunan ana kuma samun su kuma an tsara su ne sau ɗaya a rana. Ana ba da umarnin saurin-saki metformin sau biyu a rana.

Babban banbanci tsakanin glipizide da metformin
	Glipizide	Metformin
Ajin magani	Sulfonylurea	Biguanide
Alamar alama / ta kowa	Nau'in samfura da na yau da kullun akwai	Nau'in samfura da na yau da kullun akwai
Menene sunan alamar?	Glucotrol	Glucophage Riomet
Wani nau'i (s) ne miyagun ƙwayoyi ya shigo?	Rubutun baka	Rubutun baka
Menene daidaitaccen sashi?	5 MG sau ɗaya kowace rana kafin karin kumallo. Ana iya daidaita sashi bisa ga martani da yanayin kiwon lafiya. Matsakaicin matsakaici na 40 MG kowace rana.	500 MG sau biyu a rana ko 850 MG sau ɗaya a rana tare da abinci. Ana iya daidaita sashi bisa ga martani da yanayin kiwon lafiya. Matsakaicin matsakaici na 2,550 MG kowace rana.
Yaya tsawon maganin al'ada?	Dogon lokaci don gudanar da ciwon sukari	Dogon lokaci don gudanar da ciwon sukari
Wanene yawanci yake amfani da magani?	Manya yan shekaru 18 zuwa sama	Manya da yara masu shekaru 10 zuwa sama

Yanayin da glipizide da metformin suka bi da shi

Glipizide da metformin duk sun sami izinin FDA don magance Ciwon sukari na 2 mellitus. Kula da hawan sikarin cikin jini na iya taimakawa rage haɗarin rikice-rikice daga ciwon sukari. Wadannan rikitarwa na iya haɗawa da cututtukan zuciya, cututtukan koda, cutar hanta, lalacewar ido, da cututtukan ƙafa.

Metformin wani lokacin ana amfani dashi daga lakabi don magance wasu yanayi, kamar ciwon suga na ciki, ko ciwon sukari yayin ciki, da polycystic ovary ciwo (PCOS) . Hakanan ana amfani da Metformin a kashe-lakabin don kula da ƙimar da aka samu a sakamakon sakamako na wasu magungunan antipsychotic.

Babu wani muhimmin karatu da aka gudanar a kan alamun-amfani na glipizide.

Yanayi	Glipizide	Metformin
Rubuta ciwon sukari na 2	Ee	Ee
Ciwon suga na ciki	Ba	Kashe-lakabi
Polycystic ovary ciwo	Ba	Kashe-lakabi
Karuwar nauyi saboda maganin ƙwaƙwalwar ƙwaƙwalwa	Ba	Kashe-lakabi

Shin glipizide ko metformin sun fi tasiri?

Glipizide da metformin dukkansu magunguna ne masu tasiri na inganta ciwon suga don inganta kulawar glycemic a cikin mutanen da ke da ciwon sukari na Type 2. Ana iya amfani dasu azaman monotherapy ko azaman kwaya mai haɗuwa da ake kira Metaglip. Glipizide da metformin sunyi aiki mafi kyau lokacin amfani dasu tare da cin abinci mai dacewa da tsarin motsa jiki.

Metformin ya kasance maganin layin farko don cutar ciwon sikari na 2, bisa ga ƙa'idodi daga Diungiyar Ciwon Suga ta Amurka (ADA) . Idan aka kwatanta da tasiri a cikin waɗanda ke da cutar Suga ta 2 da cututtukan jijiyoyin jini, metformin yana rage haɗarin kamuwa da ciwon zuciya da shanyewar jiki fiye da glipizide. Dangane da makafi biyu, gwajin asibiti, metformin ya nuna mafi girma sakamako na zuciya fiye da glipizide bayan tsawon shekaru biyar.

Wani gwada kamanta gano cewa metformin ya samar da mafi kyawun sarrafa suga fiye da glipizide. Waɗanda ke shan metformin a cikin binciken sun fi matakan glucose na plasma azumi fiye da glipizide bayan makonni 24, 36, da 52. Wadanda suke shan metformin suma suna da kasa HbA1c matakin fiye da waɗanda ke shan glipizide bayan makonni 52. Metformin ya haifar da asarar nauyi kuma glipizide ya haifar da karɓar nauyi a cikin mahalarta masu kulawa.

Tuntuɓi mai ba da sabis na kiwon lafiya don shawarar likita kan mafi kyawun magani a gare ku idan kuna da ciwon sukari na Type 2. Ya danganta da yanayin lafiyarku gabaɗaya, matakan sukarin jini , da sauran magungunan da zaka iya sha, ana iya fifita magani daya akan daya.

Kuna son mafi kyawun farashi akan Glipizide?

Yi rajista don faɗakarwar farashin Glipizide kuma gano lokacin da farashin ya canza!

Sami faɗakarwar farashi

Verageaukar hoto da kwatancen farashi na glipizide vs. metformin

Glipizide magani ne na kwayar cututtukan sikari wanda yawanci ana rufe shi ne ta Medicare da tsare-tsaren inshora. Don daidaitaccen wadataccen glipizide, yawan kuɗin zai iya kaiwa daga $ 0 zuwa $ 9. Matsakaicin farashin kiri na glipizide na iya zama kusan $ 30. Kwancen SingleCare glipizide na iya taimakawa rage farashin zuwa $ 4 a shagunan sayar da magani.

Metformin magani ne wanda aka ba da izini game da cututtukan sukari wanda yawancin shirin Medicare da inshora ke rufe shi. Ayididdigar aikin likita na yau da kullun na iya zuwa daga $ 0 zuwa $ 8, kuma farashin tallace-tallace na iya zama kusan $ 25 dangane da kantin magani da kuka je. Kwancen metformin coupon daga SingleCare na iya rage farashin zuwa ƙasa da $ 4.

	Glipizide	Metformin
Yawanci inshora ke rufe shi?	Ee	Ee
Yawanci an rufe shi ta Medicare Part D?	Ee	Ee
Daidaitaccen sashi	5 MG sau ɗaya a rana (adadin allunan 60)	500 MG sau biyu a rana (adadin allunan 60)
Hanyar biyan kuɗaɗe na Medicare	$ 0– $ 9	$ 0– $ 8
SingleCare kudin	$ 4 +	$ 4 +

Sakamakon illa na yau da kullun na glipizide vs. metformin

Sakamakon illa na yau da kullun na glipizide sun haɗa da ƙarancin suga ( hypoglycemia ), maƙarƙashiya, gudawa, tashin zuciya, da jiri.

Illolin dake tattare da cutar metformin sun hada da gudawa, jiri, rauni (ashenia), hypoglycemia, da ciwon kai.

M sakamako masu illa na glipizide sun hada da hypoglycemia mai tsanani da kuma rashin jini. Babban illa na metformin sun haɗa da lactic acidosis da kuma rashin bitamin B12. Tuntuɓi mai ba da kiwon lafiya don sauran tasirin tasirin glipizide ko metformin.

	Glipizide	Metformin
Sakamakon sakamako	Ana amfani?	Mitar lokaci	Ana amfani?	Mitar lokaci
Hypoglycemia	Ee	*	Ee	1% –5%
Maƙarƙashiya	Ee	*	Ba	-
Gudawa	Ee	*	Ee	53%
Ciwan	Ee	*	Ee	26%
Dizziness	Ee	*	Ba	-
Rashin ƙarfi	Ba	-	Ee	9%
Ciwon kai	Ee	*	Ee	6%

* ba'a ruwaito ba
Mitar ba ta dogara da bayanai daga gwajin kai-da-kai. Wannan na iya zama ba cikakken jerin tasirin illa bane wanda zai iya faruwa. Da fatan za a koma zuwa likitanku ko mai ba da sabis na kiwon lafiya don ƙarin koyo.
Source: DailyMed ( Glipizide ,, DailyMed ( Metformin )

Magungunan ƙwayoyi na glipizide vs. metformin

Glipizide da metformin na iya yin ma'amala da magunguna iri ɗaya. Wasu magunguna na iya ƙara tasirin tasirin suga na glipizide da metformin, wanda zai iya ƙara haɗarin hypoglycemia. Wadannan kwayoyi sun hada da wasu magungunan masu cutar sikari da wasu masu saukar da hawan jini kamar masu hana ACE da masu hana karbar sigina irin na angiotensin.

Wasu kwayoyi na iya rage yadda glipizide da metformin suke aiki, wanda zai iya rage tasirin tasirin sukarin jinin su. Waɗannan ƙwayoyi na iya haɗawa da masu toshe tashar calcium, diuretics, corticosteroids, beta blockers, da magungunan hana haihuwa na baki. Ana iya rufe alamun hypoglycemia yayin shan beta, don haka ya kamata a sanya musu ido a kan mutanen da ke shan waɗannan magunguna.

Metformin zai iya yin ma'amala tare da masu hana ƙarancin amfani na anhydrase, kamar topiramate da zonisamide, wanda zai iya ƙara haɗarin lactic acidosis. Sauran magunguna kamar ranolazine da vandetanib na iya yin hulɗa tare da metformin kuma su tsoma baki tare da kawar da shi daga kodan. Wadannan kwayoyi na iya kara matakan metformin a cikin jini da kuma kara kasadar lactic acidosis.

Drug	Ajin magani	Glipizide	Metformin
Topiramate Zonisamide Acetazolamide Dichlorphenamide	Carbonic anhydrase masu hanawa	Ba	Ee
Ranolazine	Tsoffin abubuwa	Ba	Ee
Vandetanib	Tyrosine kinase masu hanawa	Ba	Ee
Insulin Sitagliptin Dulaglutide Dapagliflozin Miglitol	Magungunan ciwon sikari	Ee	Ee
Lisinopril Enalapril Captopril	ACE masu hanawa	Ee	Ee
Candesartan Irbesartan Losartan	Angiotensin II masu hana masu karɓar rashi	Ee	Ee
Amlodipine Nicardipine Verapamil	Masu toshe tashar calcium	Ee	Ee
Hydrocortisone Prednisone Methylprednisolone	Corticosteroids	Ee	Ee
Hydrochlorothiazide Chlorthalidone Indapamide Furosemide Bumetanide	Diuretics	Ee	Ee
Atenolol Bisoprolol Metoprolol	Masu hana Beta	Ee	Ee
Haɗa estrogens Ethinyl estradiol Levonorgestrel Norethindrone	Estrogens da maganin hana haihuwa na baki	Ee	Ee

Tuntuɓi ƙwararren masanin kiwon lafiya don sauran hanyoyin hulɗa da ƙwayoyi

Gargaɗi na glipizide da metformin

Saboda tasirin saukarda glucose, glipizide da metformin suna ɗauke da haɗarin hypoglycemia, ko ƙananan matakan sukarin jini. Haɗarin hypoglycemia yana ƙaruwa lokacin da ake shan glipizide ko metformin tare da wasu masu maganin cutar ta siga. Doguwar motsa jiki da shan barasa na iya ƙara wannan haɗarin. Kwayar cututtukan hypoglycemia sun hada da juyayi, zufa, bugun zuciya da sauri, da rudani.

Wasu mutane masu fama da rashi glucose 6-phosphate dehydrogenase (G6PD) suna cikin haɗarin kamuwa da cutar anemia yayin shan glipizide. Koyaya, wasu mutane ba tare da rashi na GP6D ba na iya haifar da cutar ƙarancin jini.

Yin amfani da metformin na iya haifar da lactic acidosis da ke haɗuwa da metformin. Wannan nau'in lactic acidosis yawanci ana haɗuwa da yawan ƙwayar metformin. Koyaya, akwai kuma haɗarin lactic acidosis a cikin mutanen da ke rage aikin hanta ko koda. Alamomi da alamomin cutar lactic acidosis sun hada da jiri, rashin karfin jini, da ciwon ciki.

Tuntuɓi mai ba da sabis na kiwon lafiya don wasu ƙarin faɗakarwa da kiyayewa masu alaƙa da glipizide ko metformin.

Tambayoyi akai-akai game da glipizide vs. metformin

Menene gipizide?

Glipizide magani ne na asali wanda yake cikin rukunin magungunan da ake kira sulfonylureas. Sunan glipizide shine Glucotrol. Glipizide yana aiki ta hanyar ƙara sakin insulin daga pancreas don rage matakan sukarin jini. Ana samunsa azaman saki mai ɗorewa da ƙarawa-fitarwa na baka.

Menene metformin?

Metformin kuma sanannun sanannun sunaye ne kamar Riomet da Glucophage. Yana cikin rukunin magungunan cututtukan sukari da ake kira biguanides. Metformin yana aiki ta haɓaka ƙwarewar insulin, rage samar da glucose a cikin hanta, da rage shan kwayar glucose. Metformin yana nan a matsayin saki-fitarwa da ƙara-fitarwa na kwamfutar hannu na baka.

Shin glipizide da metformin iri daya ne?

Glipizide da metformin ba iri daya bane. Glipizide shine sulfonylurea wanda ke kula da ciwon sukari Nau'in na biyu a cikin manya kuma metformin shine babban maganin da ke kula da ciwon sukari na 2 na manya da yara waɗanda shekarunsu suka wuce 10 zuwa sama. Glipizide da metformin suna aiki ta hanyoyi daban-daban kuma suna da nau'ikan abubuwa daban-daban.

Shin glipizide ko metformin sun fi kyau?

Glipizide da metformin duka suna aiki don rage matakan glucose na jini a cikin waɗanda ke da ciwon sukari na Type 2. A cewar Asusun Baƙin Amurka na Ciwon Suga jagororin , metformin shine maganin layi na farko don ciwon sukari na Type 2. Sometimesila wasu lokuta ana iya ɗaukar glipizide da metformin tare a wasu lokuta inda ake buƙatar sakamako mafi girma na rage glucose. Gabaɗaya, mafi kyawun maganin ciwon sukari ya dogara da yanayin lafiyarku gaba ɗaya da kuma martani ga magani.

Zan iya amfani da glipizide ko metformin yayin da nake da juna biyu?

Idan aka kwatanta da metformin, glipizide na iya samun damar da zata iya haifar da cutar mai tayi. Dangane da nazarin dabba, metformin na iya zama mai aminci don amfani yayin ciki; amma ba a sami cikakken bincike a cikin mutane ba. Tuntuɓi mai ba da lafiya don ƙayyade mafi kyawun zaɓin magani a gare ku yayin da kuke ciki.

Zan iya amfani da glipizide ko metformin tare da barasa?

Ba'a da shawarar yin amfani da giya mai yawa yayin shan glipizide ko metformin . Shan barasa na iya haifar da matakan sukarin jini wanda ba za a iya hango shi ba kuma ya kara barazanar hypoglycemia ko hyperglycemia. Alkahol na iya ƙara haɗarin lactic acidosis yayin kan metformin

Menene lokaci mafi kyau na rana don ɗaukar gilashi?

Mafi kyawun lokacin shan glipizide shine kafin cin abinci domin rage haɗarin hypoglycemia. Idan ana shan shi sau daya a rana, ana bada shawarar a dauki glipizide kafin cin abincin farko na yini.

Shin glipizide yana da kyau ga kodan?

Ciwon suga na 2 da ba a sarrafawa na iya haifar da rikitarwa kamar lalacewar koda. Koyaya, ba a san glipizide da zai haifar da illa ga kodan ba. Kawar glipizide na iya raguwa a cikin mutane masu cutar koda. Haɗuwar glipizide na iya haifar da haɗarin ƙananan matakan sukarin jini.

Menene magani mafi aminci ga ciwon Suga na 2?

Metformin yawanci ana tsara shi azaman maganin layi na farko don ciwon sukari na 2 a yawancin mutane. Wannan saboda metformin ba shi da tsada, mai aminci, kuma yana da tasiri. Idan aka kwatanta da sauran cututtukan sukari, ana danganta metformin da ƙananan ko matakan HbA1c kama . Amfani da metformin yana haɗuwa da ƙananan haɗarin hypoglycemia fiye da sauran magunguna kamar sulfonylureas.