Etodolac vs. ibuprofen: Bambanci, kamanceceniya, kuma wanene yafi muku alheri
Magunguna vs. AbokiBayanin magunguna & manyan bambance-bambance | Yanayin da aka bi | Inganci | Inshorar inshora da kwatancen farashi | Sakamakon sakamako | Hadin magunguna | Gargadi | Tambayoyi
Ba wanda yake son rayuwa tare da rashin jin daɗi ko ciwo na dogon lokaci, ko kwata-kwata ga wannan. Abin farin ciki, ana samun wadatar magani da magungunan rage radadi a shagon sayar da magani mafi kusa. Duk da yake ba su da ƙarfi kamar masu sauƙin ciwo na opioid, waɗanda ke buƙatar ƙarin zurfin nazarin likita da takardar sayan magani, NSAIDs kamar etodolac ko ibuprofen suna da tasiri don magance ciwo mai sauƙi zuwa matsakaici.
In ba haka ba da aka sani da nonsteroidal anti-inflammatory drugs, NSAIDs suna aiki ta hanyar hana fitowar prostaglandins. Jikinku na iya amsawa ga wasu sharuɗɗan kiwon lafiya ta hanyar samar da prostaglandins, waɗanda sune sunadarai masu alhakin ciwo, kumburi, da zazzabi. NSAIDs suna toshe enzymes masu samar da prostaglandin-COX-1 da COX-2-don sarrafa amsar kumburin jiki da rage ciwo.
Etodolac da ibuprofen an lasafta su azaman NSAIDs. Koyaya, suna da wasu mahimman bambance-bambance.
Menene manyan bambance-bambance tsakanin etodolac da ibuprofen?
Etodolac wani lokaci ana san shi da sunan sa (yanzu an daina shi), Lodine. Ana samun sa azaman magani na asali kuma ana iya samun sa tare da takardar likita.
Etodolac yana da rabin rai na kusan awanni shida zuwa bakwai kuma ya kai matuka cikin jini awa ɗaya zuwa biyu bayan shanye shi. Yawanci ana ɗauka sau biyu zuwa sau uku kowace rana don ciwo daga cututtukan zuciya. Hakanan akwai ƙaramin juzuwar etodolac wanda yake da rabin rai na kusan awa takwas kuma za'a iya ɗauka sau ɗaya a rana.
Ibuprofen shine mafi yawan NSAID wanda ke kan layi (OTC). Hakanan ana samun ƙarfin ƙarfin ibuprofen tare da takardar likita. Shahararrun sunayen suna na ibuprofen sun hada da Advil, Motrin, da Midol.
Ibuprofen ya kai matakin jini a cikin awa daya zuwa biyu bayan shan sa. Koyaya, ba kamar etodolac ba, ibuprofen yana da ɗan gajeren rabin rayuwa awa biyu . Uparfin ibuprofen ya zo a cikin kwamfutar hannu wanda yawanci ana ɗauka sau uku zuwa sau hudu a kowace rana. Sigar OTC yazo a cikin allunan baka, kwantena, da kuma dakatarwar ruwa.
| Babban bambance-bambance tsakanin etodolac da ibuprofen | ||
|---|---|---|
| Etodolac | Ibuprofen | |
| Ajin magani | Magungunan anti-inflammatory marasa ƙwayar cuta (NSAID) | Magungunan anti-inflammatory marasa ƙwayar cuta (NSAID) |
| Alamar alama / ta kowa | Samfuran samfuran (an daina amfani da su) | Nau'i da janar akwai |
| Menene sunan alamar? | Lodine | Advil, Motrin, Midol |
| Wani nau'i (s) ne miyagun ƙwayoyi ya shigo? | Maganin baka Rubutun baka Rubutun baka, fadada-saki | Maganin baka Rubutun baka Ruwan baka Allura (NeoProfen) |
| Menene daidaitaccen sashi? | Don ciwo: 200 zuwa 400 MG kowane 6 zuwa 8 hours kamar yadda ake bukata. Kar ku wuce iyakar nauyin 1200 MG kowace rana. Don osteoarthritis ko rheumatoid arthritis: Saki 300 MG sau biyu zuwa sau uku a kowace rana ko 400 zuwa 500 MG sau biyu a rana. Releaseaddamar da saki 400 zuwa 1000 MG sau ɗaya kowace rana. Kar ku wuce iyakar nauyin 1200 MG kowace rana. | Don ciwo: 200 zuwa 400 MG kowane 4 zuwa 6 hours kamar yadda ake bukata. Karka wuce matsakaicin magani na 1200 MG kowace rana saidai in likita ya umurta. Don cututtukan osteoarthritis ko cututtukan zuciya na rheumatoid: 400 zuwa 800 MG sau uku zuwa sau hudu a kowace rana. Kar a wuce iyakar nauyin 3200 MG kowace rana. |
| Yaya tsawon maganin al'ada? | Tsawan lokacin jiyya ya dogara da yanayin lafiya, tsananin ciwo, da wasu dalilai. Jiyya na iya zama na ɗan lokaci ko na dogon lokaci. | Tsawan lokacin jiyya ya dogara da yanayin lafiya, tsananin ciwo, da wasu dalilai. Jiyya na iya zama na ɗan lokaci ko na dogon lokaci. |
| Wanene yawanci yake amfani da magani? | Manya da yara 'yan shekara 6 zuwa sama | Manya da yara wata 6 zuwa sama |
Yanayin da etodolac da ibuprofen suka kula dashi
Ana yiwa Etodolac da ibuprofen alama don magance ciwo. Ana yawan ɗauke su don magance ciwo mai sauƙi zuwa matsakaici daga hanyoyin haƙori, ƙaura , ko ciwon jiji (myalgia).
Etodolac da ibuprofen suna da amfani musamman kuma an amince da FDA don magance ciwo da kumburi daga cututtukan osteoarthritis da cututtukan zuciya na rheumatoid. Mafi yawan ƙarfi ana buƙata don magance ƙarin haɗin gwiwa mai tsanani ko ciwon ƙashi wanda ke da alaƙa da cututtukan zuciya. A wasu lokuta, ana iya kula da yara sama da shawarar shekarun da aka ba da shawarar tare da waɗannan NSAIDs don cututtukan yara na idiopathic .
An yi wa lakabi da kan-kan-kantocin ibuprofen don magance zazzabi da ciwan mara (farkon dysmenorrhea). Wani nau'in allurar ibuprofen da ake kira NeoProfen ana amfani dashi don magance patent ductus arteriosus (PDA), wani nau'in nakasawar zuciya, a cikin jarirai da basu isa haihuwa ba.
| Yanayi | Etodolac | Ibuprofen |
| Zafi | Ee | Ee |
| Osteoarthritis | Ee | Ee |
| Rheumatoid amosanin gabbai | Ee | Ee |
| Arthwararrun cututtukan cututtukan yara | Ee | Ee |
| Zazzaɓi | Ba | Ee |
| Cutar dysmenorrhea | Ba | Ee |
| Patent ductus arteriosus | Ba | Ee |
Shin etodolac ko ibuprofen yafi tasiri?
Dukansu etodolac da ibuprofen suna da tasiri NSAIDs don sauƙin ciwo. Dukansu suna toshe enzymes na cyclooxygenase (COX) don sarrafa kumburi da rage ciwo ga waɗanda suke tare da cututtukan zuciya. Koyaya, sakamakon etodolac ya ɗan ƙara tsayi. Sabili da haka, wasu mutane na iya fifita etodolac don ƙarancin saurin saiti.
A cikin binciken makafi biyu kwatanta etodolac da ibuprofen , An baiwa marasa lafiya 1,446 masu cutar cututtukan zuciya ko dai MG 150 na etodolac sau biyu a rana, 500 mg etodolac sau biyu a rana, ko 600 mg na ibuprofen sau hudu a kowace rana. Dukkanin maganin etodolac an same su da kamanninsu cikin ingancin maganin ibuprofen. Dangane da illoli, waɗanda ke shan etodolac sun sami rashin narkewar abinci, kumburi, da zubar jini fiye da waɗanda suke shan ibuprofen. Koyaya, wannan na iya kasancewa da alaƙa da adadin marasa lafiyar da aka basu.
Duk da yake babu wasu gwaji na asibiti da suka kwatanta etodolac da ibuprofen kai tsaye, karatu daban daban sun gwada sauran NSAIDs zuwa etodolac ko ibuprofen. Metaaya daga cikin bayanan bincike ya gano cewa matsakaicin adadin yau da kullun na diclofenac ya fi tasiri fiye da matsakaiciyar maganin ibuprofen, naproxen, da selecoxib (amma mafi ƙarancin tasiri na NSAIDs koyaushe ana ba da shawarar). Wani meta-bincike ya gano cewa wasu NSAIDs kamar piroxicam da azapropazone suna da babban haɗarin guba yayin da ibuprofen mai ƙaramin ƙarfi yana da ƙananan haɗarin guba. Gabaɗaya, ana iya cewa NSAIDs suna da bambanci sosai a cikin aminci maimakon tasiri.
Saboda yawancin zaɓuɓɓuka don ciwo, yana da mahimmanci a tuntuɓi mai ba da kiwon lafiya don mafi kyawun zaɓin magani. Wani likita ko mai ba da sabis na kiwon lafiya na iya ba da shawarar likita mai dacewa don takamaiman yanayin kiwon lafiya.
Verageaukar hoto da kwatancen farashi na etodolac vs. ibuprofen
Generic etodolac Allunan galibi ana rufe su ne ta hanyar Medicare da tsare-tsaren inshora. Idan kana da yanayin kiwon lafiya kamar amosanin gabbai, shirin inshora zai iya rufe etodolac don ciwo. Matsakaicin farashin siyar da etodolac na iya bambanta dangane da sashi, amma zaka iya biyan kusan $ 50 don etodolac ta amfani da coupon SingleCare a shagunan sayar da magani.
Tunda ana samun ibuprofen a kan-kan-kan, wasu hanyoyin ba za a iya rufe su da tsare-tsaren inshora ba. Koyaya, yawancin Medicare Sashe na D da tsare-tsaren inshora yakamata su rufe allunan magani-ƙarfi ibuprofen ya danganta da tsarin kulawa. Gabaɗaya, ibuprofen ya fi araha da etodolac. Yi amfani da coupon SingleCare don ibuprofen idan kuna da takardar sayan magani daga mai ba da lafiyar ku.
| Etodolac | Ibuprofen | |
| Yawanci inshora ya rufe? | Ee | Ee (allunan-strengtharfin allunan) |
| Yawanci an rufe shi ta Medicare Part D? | Ee | Ee |
| Daidaitaccen sashi | 300 MG 2 zuwa sau 3 kowace rana | 400 zuwa 800 MG 3 zuwa 4 sau yau |
| Hanyar biyan kuɗaɗe na Medicare | $ 0– $ 76 | $ 0– $ 22 |
| SingleCare kudin | $ 40- $ 80 | $ 4 - $ 24 |
Sakamakon illa na yau da kullun na etodolac vs. ibuprofen
Abubuwan da suka fi dacewa na NSAIDs, gami da etodolac da ibuprofen, sune tashin zuciya, rashin narkewar abinci (dyspepsia), maƙarƙashiya, zawo, da ciwon ciki ko ciki. Baya ga illa masu illa na ciki, NSAIDs na iya haifar da dizziness, kumburi a hannu ko ƙafa (edema), ciwon kai, kumburi, da ringing a kunnuwa (tinnitus). Yawancin illolin etodolac da ibuprofen suna da sauƙi kuma suna tafiya da kansu.
M sakamako masu illa na NSAIDs na iya haɗawa da halayen rashin lafiyan, kamar su kurji mai tsanani ko anaphylaxis, daga mayuka masu aiki ko marasa aiki. Sauran cututtukan cututtuka masu haɗari sun haɗa da cututtukan ciki kamar na ciki da jini peptic ulcers . Tuntuɓi mai ba da lafiyar ku idan kun sami jini a cikin kumburi, asarar nauyi, ko kuma ciwon ciki mai tsanani.
| Etodolac | Ibuprofen | |||
| Sakamakon sakamako | Ana amfani? | Mitar lokaci | Ana amfani? | Mitar lokaci |
| Ciwan | Ee | 1% –10% | Ee | 1% –3% |
| Ciwon ciki | Ee | 1% –10% | Ee | 1% –3% |
| Rashin narkewar abinci | Ee | 1% –10% | Ee | 1% –3% |
| Maƙarƙashiya | Ee | 1% –10% | Ee | 1% –3% |
| Gudawa | Ee | 1% –10% | Ee | 1% –3% |
| Dizziness | Ee | 1% –10% | Ee | 1% –3% |
| Edema | Ee | 1% –10% | Ee | 1% –3% |
| Ciwon kai | Ee | 1% –10% | Ee | 1% –3% |
| Rash | Ee | 1% –10% | Ee | 1% –3% |
| Tinnitus | Ee | 1% –10% | Ee | 1% –3% |
Wannan na iya zama ba cikakken jerin illolin da zasu iya faruwa ba. Da fatan za a koma zuwa likitanku ko mai ba da sabis na kiwon lafiya don ƙarin koyo.
Source: DailyMed ( Etodolac ,, DailyMed ( Ibuprofen )
Magungunan ƙwayoyi na etodolac vs. ibuprofen
Saboda suna toshe enzyme na COX-1, wanda ke taka rawa wajen samar da platelet da kuma daskarewar jini, NSAIDs na iya tsoma baki tare da tasirin masu ƙarancin jini. NSAIDs na iya ƙara haɗarin zub da jini daga wakilan antiplatelet kamar su asfirin da kuma masu shan jini kamar warfarin.
Etodolac da ibuprofen na iya sa jiki ya riƙe ruwa kuma ya shafi aikin kodan. A sakamakon haka, waɗannan NSAIDs na iya ƙara hawan jini. Idan kai ma kana shan maganin hawan jini (antihypertensive), kamar su lisinopril ko losartan, hawan jininka na iya bukatar a sa ido yayin shan NSAID.
Etodolac da ibuprofen na iya shafar yadda ake tsarkake cyclosporine, digoxin, ko methotrexate daga jiki. Samun NSAID na iya haifar da ƙarin haɗarin cyclosporine, digoxin, ko cutar methotrexate.
Nemo wasu hanyoyin hulɗa na miyagun ƙwayoyi a ƙasa.
| Drug | Ajin magani | Etodolac | Ibuprofen |
| Asfirin | Antiplatelet | Ee | Ee |
| Warfarin | Anticoagulant | Ee | Ee |
| Lisinopril Captopril Ramipril | Angiotensin-converting enzyme (ACE) mai hanawa | Ee | Ee |
| Losartan Valsartan Olmesartan | Angiotensin mai karɓar mai karɓa (ARB) | Ee | Ee |
| Furosemide Hydrochlorothiazide | Diuretic | Ee | Ee |
| Lithium | Yanayin kwanciyar hankali | Ee | Ee |
| Samun bayanai An gyara shi | Antimetabolite | Ee | Ee |
| Cyclosporine | Tsarin rigakafi | Ee | Ee |
| Digoxin | Cardiac glycoside | Ee | Ee |
Tuntuɓi ƙwararren masanin kiwon lafiya don sauran hanyoyin hulɗa da ƙwayoyi.
Gargadi na etodolac da ibuprofen
Etodolac da ibuprofen, kamar sauran NSAIDs, na iya ƙara haɗarin mummunan cututtukan zuciya na zuciya kamar na zuciya da bugun jini. NSAID ya kamata a guji ko sanya ido a cikin mutane tare da matsalolin zuciya kamar ciwon zuciya, ciwon zuciya, da hawan jini.
Yin amfani da etodolac ko ibuprofen na iya haifar da ƙarin haɗarin mummunan lamuran ciki (GI), kamar zub da jini na ciki da ulcer. Ba tare da magani mai kyau ba, kumburi, da zubar jini a cikin hanyar GI na iya zama m. Tsoffin mutane na iya samun babban haɗarin mummunan abubuwan GI.
Kada a yi amfani da NSAIDs dama kafin ko bayan aikin zuciya da ake kira tiyatar jijiya ta jijiya (CABG) tiyata .
Waɗanda ke da cutar koda na iya kasancewa cikin haɗarin ƙarin matsalolin koda yayin shan NSAIDs.
Tuntuɓi mai ba da lafiyar ku don wasu kariya kafin ɗaukar NSAID.
Tambayoyi akai-akai game da etodolac vs. ibuprofen
Menene etodolac?
Etodolac magani ne mai kashe kumburi (NSAID) wanda ake amfani dashi don magance ciwo da kumburi. An amince da FDA don magance osteoarthritis da cututtukan zuciya na rheumatoid a cikin manya. Generic etodolac kawai za'a iya samu ta takardar sayan magani.
Menene ibuprofen?
Ibuprofen sananne ne sanannun sunaye kamar Advil da Motrin. Akwai wadatar kan-kanti don magance rauni mai sauƙi zuwa matsakaici, zazzaɓi, da ciwon mara na al'ada. Za a iya samun ibuprofen mai ƙarfi tare da takardar sayan magani don magance ciwo da kumburi daga cututtukan osteoarthritis da cututtukan zuciya na rheumatoid.
Shin etodolac da ibuprofen iri daya ne?
Etodolac da ibuprofen ba iri daya bane. Duk da yake dukansu NSAIDs ne, suna da bambance-bambance a cikin allurai da yadda ake amfani dasu. Etodolac magani ne na likitanci da aka fara amfani dashi don manya da cututtukan zuciya. Ibuprofen ya fi sauƙi a matsayin magani na kan-kano don ƙananan ciwo da zazzabi.
Shin etodolac ko ibuprofen yafi kyau?
Mafi kyawun NSAID ya dogara da kashi da kuka sha da abin da kuke ɗauka don shi. Idan aka kwatanta da ibuprofen, etodolac ya daɗe a jiki, don haka, ana iya ɗaukar shi sau da yawa a cikin yini. Koyaya, yana iya zama mafi tsada fiye da ibuprofen. Dangane da yanayin lafiyar ku duka, likitanku na iya bayar da shawarar ɗaya akan ɗayan.
Zan iya amfani da etodolac ko ibuprofen yayin da nake da juna biyu?
Etodolac da ibuprofen ba a ba da shawarar galibi yayin ɗaukar ciki. Amfani da NSAIDs yayin ɗaukar ciki yana haɗuwa da haɗarin lahani na haihuwa ko zubar da ciki, musamman a lokacin ƙarshen ciki. Tuntuɓi mai ba da lafiyar ku idan kuna la'akari zaɓuɓɓukan magani yayin da suke ciki .
Zan iya amfani da etodolac ko ibuprofen tare da barasa?
Alcoholaramar shan giya na iya zama mai kyau a wani lokaci yayin ɗaukar NSAID. Koyaya, shan giya mai yawa na iya haifar da haɗarin haɗarin cututtukan ciki da NSAIDs. Barasa da NSAIDs na iya harzuka ciki da rufin hanji, wanda zai haifar da ulce ko zubar jini.
Shin etodolac mai kashe zafi ne?
Etodolac mai kashe ciwo ne mai tasiri. Yana da tasiri sosai don magance ciwo da kumburi wanda cututtukan zuciya suka haifar. Har ila yau, yana da amfani don magance ciwo mai tsanani bayan wasu hanyoyin kamar tiyatar hakori.
Shin etodolac ya fi naproxen ƙarfi?
Amfani da NSAIDs ya dogara da ƙimar da aka ɗauka, a tsakanin sauran dalilai. Duk abubuwa daidai suke, etodolac da naproxen suna kamantawa dangane da tasiri. Dangane da karatun makafi biyu, etodolac da naproxen sune daidai tasiri don magance cututtukan zuciya na rheumatoid. Dukansu magungunan an yarda dasu sosai dangane da lahani.
