Main >> Magunguna Vs. Aboki >> Abilify vs. Rexulti: Bambanci, kamance, kuma wanne ne mafi alheri a gare ku

Abilify vs. Rexulti: Bambanci, kamance, kuma wanne ne mafi alheri a gare ku

Magunguna vs. Aboki

Abilify (aripiprazole) da Rexulti (brexpiprazole) dukansu magungunan zafin jiki ne. Dukkanin magungunan sun sami karbuwa daga Hukumar Abinci da Magunguna ta Amurka (FDA). Hakanan ana samun Abilify a cikin tsarinta na aripiprazole. Babu Rexulti a halin yanzu a cikin sifa iri ɗaya.

Atypical antipsychotic magunguna kuma ana kiran su antipsychotics na ƙarni na biyu. Zamanin farko na maganin cututtukan zuciya, kamar haloperidol, an haɓaka su a cikin 1950s. Wadannan magunguna suna da ƙarin sakamako masu illa da yawa, kamar su extrapyramidal symptoms. Extrapyramidal bayyanar cututtuka suna haifar da toshewar dopamine. Wadannan alamun sun hada da rikicewar motsi kamar rashin motsi da motsawar jijiyoyin jiki, rashin iya zama har yanzu, rawar jiki, da lumshe ido mara kyau.

Antiwararrun masu ba da maganin ƙwaƙwalwa na ƙarni na biyu, kamar Abilify da Rexulti, sababbi ne kuma ba su da ƙananan illolin cutarwa. Saboda sun fi jurewa, sune magungunan da aka fi so akan tsofaffin cututtukan ƙwaƙwalwa.

Ta yaya maganin rashin lafiya na rashin kwakwalwa, kamar Abilify da Rexulti, ke aiki? Ba a san ainihin aikin aikin ba. Ana tunanin suyi aiki akan masu karɓa na D2 na dopamine da serotonin-5-HT1A da masu karɓar 5-HT2A a cikin kwakwalwa, suna taimakawa alamun cututtukan schizophrenia ko wasu rikice-rikice. Rexulti yana da kwatankwacin tsari da tsari kamar na Abilify, wanda yasa su zama kama, amma ba daidai bane. Ci gaba karatu don koyon komai game da Abilify da Rexulti.

Menene manyan bambance-bambance tsakanin Abilify da Rexulti?

Abilify da Rexulti duka magunguna ne masu ba da tabin hankali. Abilify (aripiprazole) yana nan a cikin sifa da tsari iri ɗaya, kuma a yanzu ana samun Rexulti (brexpiprazole) kawai cikin sunan alama. Dukansu magunguna suna nan a cikin sifar kwamfutar hannu. Abilify ana samun sa a cikin wasu nau'ikan sashi (duba ginshiƙi a ƙasa don cikakkun bayanai).

Babban banbanci tsakanin Abilify da Rexulti
	Abilify	Rexulti
Ajin magani	Atypical antipsychotic	Atypical antipsychotic
Alamar alama / ta kowa	Brand da janar	Alamar
Menene sunan gama-gari?	Aripiprazole	Brexpiprazole
Wani nau'i (s) ne miyagun ƙwayoyi ya shigo?	Tablet, allunan da ke wargajewa, maganin baka, allura, allura mai dogon aiki (depot)	Kwamfutar hannu
Menene daidaitaccen sashi?	Bambanci: yawancin marasa lafiya manya suna shan 5 zuwa 15 MG ta baki kowace rana	Bambanci: yawancin marasa lafiya manya suna ɗaukar 1 zuwa 4 MG ta baki kowace rana
Yaya tsawon maganin al'ada?	Bambanci: ya kamata a sake duba marasa lafiya lokaci-lokaci	Bambanci: ya kamata a sake duba marasa lafiya lokaci-lokaci
Wanene yawanci yake amfani da magani?	Manya da yara (shekarun da za'a iya amfani da Abilify ya dogara da yanayin)	Manya

Kuna son mafi kyawun farashi akan Abilify?

Yi rajista don faɗakarwar farashin Abilify kuma gano lokacin da farashin ya canza!

Sami faɗakarwar farashi

Yanayin da Abilify da Rexulti suka kula dashi

Abilify da Rexulti duk an nuna su don maganin cutar rashin lafiya. An kuma yarda da su duka azaman maganin ci gaba (a haɗe tare da maganin antidepressant) don maganin babbar cuta mai ɓarna (MDD).

Bugu da ƙari, Abilify na iya magance bipolar I cuta (m magani na manic da gauraye aukuwa ko magani mai kulawa), rashin lafiyar Tourette, da rashin jin daɗi saboda rashin lafiyar autistic. Ana amfani da nau'in allura na Abilify don tsananin maganin tashin hankali wanda cutar schizophrenia ko bipolar ta haifar.

Yanayi	Abilify	Rexulti
Jiyya na schizophrenia	Ee	Ee
Bipolar I cuta (m da kuma kulawa)	Ee	Ba
Magungunan haɗin gwiwa don maganin ƙwaƙwalwar ciki don ɓacin rai	Ee	Ee
Rashin haushi da ke tattare da cutar autistic	Ee	Ba
Jiyya na rashin lafiyar Tourette	Ee	Ba
M magani na tashin hankali saboda schizophrenia ko bipolar cuta	Ee (nau'in allura)	Ba

Shin Abilify ko Rexulti yafi tasiri?

Akwai ƙananan bayanai da ke kwatanta Abilify da Rexulti kai tsaye.

An labarin a cikin Ci Gaban Lafiya a Psychopharmacology ya kalli bayanai da nazarin karatu (meta-analysis). Masu binciken sun ƙarasa da cewa Rexulti ya haifar da ƙananan sakamako na akathisia (rikicewar motsi), rashin barci, rashin nutsuwa, tashin zuciya, ƙimar nauyi, da kwantar da hankali saboda ayyukanta a takamaiman masu karɓa.

Abubuwan da ke tattare da motsi na Abilify, kodayake, sun zama kamar masu sauƙi ne kuma ana sarrafa su ta hanyar samun mai maganin ya rage ƙimar. Babban farashi mai suna Rexulti na iya zama mahimmin abu ga marasa lafiya da yawa, idan aka kwatanta da ƙananan farashin Abilify.

Karami karatu idan aka kwatanta da Abilify da Rexulti a cikin marasa lafiya masu fama da cutar rashin hankali (a cikin asibiti) kuma sun sami magungunan biyu suna da tasiri iri ɗaya. Marasa lafiya da ke shan Rexulti sun ɗan sami kaɗan karin kayan kwalliya sakamako masu illa. Yana da mahimmanci a lura da iyakancewa cewa wannan binciken binciken karatu ne na lakabi (inda duka masu bincike da marasa lafiya suka san wane magani ne mai haƙuri ke sha). Nazarin buɗaɗɗen lakabi ba shi da inganci kamar binciken makafi biyu inda babu son zuciya.

Daya karatu ya kalli sakamakon sakamako na karɓar nauyi daga Abilify da Rexulti. Binciken ya kammala cewa duka kwayoyi suna da irin wannan tasirin akan nauyin jiki (ƙaruwar kusan 5-10 lbs) bayan shekara guda.

Magani mafi inganci shine wanda yake aiki mafi kyau a gare ku kuma yana da ƙananan (ko mafi haƙurin) sakamako masu illa. Mai ba ku kiwon lafiya zai iya taimaka muku yanke shawara idan Abilify ko Rexulti ya fi muku kyau, la'akari da yanayin lafiyarku da tarihinku da kuma sauran magunguna da kuka sha waɗanda za su iya hulɗa da Abilify ko Rexulti.

Kuna son mafi kyawun farashi akan Rexulti?

Yi rajista don faɗakarwar farashin Rexulti kuma gano lokacin da farashin ya canza!

Sami faɗakarwar farashi

Verageaukar hoto da kwatancen farashi na Abilify vs. Rexulti

Abilify yawanci an rufe shi da tsare-tsaren inshora, Medicare Sashe na D, da shirye-shiryen Amfani da Medicare. Kudin daga aljihu don kwatankwacin wata ɗaya na jigilar nau'ikan 5 MG zai zama kusan $ 700. Katin SingleCare na iya kawo farashin zuwa kusan $ 98.

Rexulti ya rufe yawancin, amma ba duka ba, tsare-tsaren inshora, Medicare Sashe na D, da tsare-tsaren Amfani da Medicare. Idan ka biya a aljihunka, samarwar wata guda na allunan MG guda 2 zaikai kimanin $ 240. Amfani da takaddun SingleCare zai kawo farashin kusan $ 198.

	Abilify	Rexulti
Yawanci inshora ya rufe?	Ee	Ee (yawanci)
Yawanci an rufe shi ta Medicare Part D?	Ee	Ee
Daidaitaccen sashi	30, 5 MG allunan	30, 2 MG allunan
Hanyar biyan kuɗaɗe na Medicare	$ 1- $ 7	$ 10- $ 41
SingleCare kudin	$ 98 +	$ 198 +

Illolin gama gari na Abilify vs. Rexulti

Abubuwan da aka fi sani da Abilify a cikin manya sune tashin zuciya, amai, maƙarƙashiya, ciwon kai, jiri, tashin hankali, rashin bacci, akathisia (rikicewar motsi saboda magungunan antipsychotic), da tashin hankali. Sauran illolin sun hada da rashin narkewar abinci, bushewar baki, ciwon hakori, rashin jin daɗin ciki, gajiya, taurin kai, kwantar da hankali, rawar jiki, da tari.

Abubuwan da suka fi dacewa na Rexulti waɗanda aka lissafa a cikin bayanin bayanin su ne ciwon kai, jiri, damuwa, akathisia, ƙimar nauyi, gajiya, da tashin hankali / rashin nutsuwa.

Wannan jeri ba cikakken lissafi ne na illa ba - wasu illolin na iya faruwa. Tuntuɓi ƙwararrun likitocin ku don cikakken jerin abubuwan tasirin Abilify da Rexulti.

	Abilify	Rexulti
Sakamakon sakamako	Ana amfani?	Mitar lokaci	Ana amfani?	Mitar lokaci
Ciwan	Ee	goma sha biyar%	Ee	≥1%
Amai	Ee	goma sha ɗaya%	Ba	-
Maƙarƙashiya	Ee	goma sha ɗaya%	Ee	kashi biyu
Ciwon kai	Ee	27%	Ee	7%
Dizziness	Ee	10%	Ee	3%
Tashin hankali	Ee	17%	Ee	3%
Rashin bacci	Ee	18%	Ee	≥1%
Akathisiya	Ee	13%	Ee	9%
Hankali / rashin natsuwa	Ee	19%	Ee	3%
Gajiya	Ee	6%	Ee	3%
Karuwar nauyi	Ee	kashi biyu	Ee	7%

Source: DailyMed ( Abilify ,, DailyMed ( Rexulti )

Magungunan ƙwayoyi na Abilify vs. Rexulti

Kada ku ɗauki Abilify da Rexulti tare da barasa ko magunguna waɗanda ke haifar da ɓacin rai na tsakiya (CNS). Effectsarin sakamako na iya faruwa, kamar su yawan ruɗuwa, bacci, da nakasawar kwakwalwa, wanda ke haifar da haɗarin haɗari. Sauran hulɗar da ƙwayoyi na iya haɗawa da ƙarancin jini (wanda zai iya zama barazanar rai), raguwar hawan jini, ko ƙaruwa a cikin alamomin ɓoye (ƙwayoyin cuta da ke haifar da ƙwayoyi, haifar da rawar jiki, taurin kai, da kuma saurin motsi)

Abilify ko Rexulti, a hade tare da magungunan hawan jini, na iya haifar da raguwar hawan jini. Ka nemi likitanka idan kana da hawan jini ko ka sha magani don hawan jini.

Abilify da Rexulti duk suna hulɗa tare da magungunan ƙwayoyi ta hanyar takamaiman enzymes. Magungunan da ke hana enzymes na iya ƙara matakan Abilify ko Rexulti. Magungunan da ke haifar da enzymes na iya rage matakan Abilify ko Rexulti. Idan ba za a iya guje wa haɗuwar magungunan ƙwayoyi masu yin ma'amala ba, dole ne mai maganin ya daidaita maganin.

Sauran hulɗar miyagun ƙwayoyi na iya faruwa. Tuntuɓi mai ba da kiwon lafiya don cikakken jerin hulɗar magunguna kafin ɗaukar Abilify ko Rexulti.

Drug	Ajin Magunguna	Abun hulɗa tare da Abilify?	Hulɗa tare da Rexulti?
Barasa	Barasa	Ee	Ee
Magungunan hawan jini	Maganin cututtukan jini	Ee	Ee
Carbamazepine Divalproex sodium Gabapentin Lamotrigine Levetiracetam Phenobarbital Phenytoin Pregabalin Topiramate	Anticonvulsants	Ee	Ee
Olanzapine Quetiapine Risperidone Ziprasidone	Magungunan maganin ƙwaƙwalwa	Ee	Ee
Amitriptyline Citalopram Desvenlafaxine Duloxetine Escitalopram Fluoxetine Fluvoxamine Nortriptyline Paroxetine Phenelzine Rasagiline Sertraline Tranylcypromine Venlafaxine	Magungunan Magunguna	Ee	Ee
Codein Fentanyl Hydrocodone Meperidine Methadone Morphine Oxycodone Tramadol	Opioid jin zafi	Ee	Ee
Alprazolam Clonazepam Diazepam Lorazepam Temazepam	Benzodiazepines	Ee	Ee
Baclofen Carisoprodol Cyclobenzaprine Metaxalone	Relaxarfafa tsoka	Ee	Ee
Clarithromycin Itraconazole Ketoconazole	Masu hana enzyme CYP3A4	Ee	Ee
Fluoxetine Paroxetine Quinidine	Masu hana enzyme CYP2D6	Ee	Ee
Carbamazepine Rifampin St John's wort	Yanayin enzyme CYP3A4	Ee	Ee

Gargadi na Abilify da Rexulti

Saboda Abilify da Rexulti sun yi kama, suna da gargaɗi iri ɗaya:

Akwai gargaɗin akwatin baƙar fata, wanda shine gargaɗi mafi ƙarfi da FDA ke buƙata.
Abilify da Rexulti ba a yarda da su kula da tsofaffi marasa lafiya da ke da nasaba da cutar hauka ba. Wadannan marasa lafiya suna cikin haɗarin haɗarin mutuwa. Magungunan antidepressant suna ƙara haɗarin tunanin kashe kai da halayyar marasa lafiya shekaru 24 da ƙananan. Kula da marasa lafiya na kowane zamani waɗanda ke ɗaukar antidepressants don ɓacin rai, canje-canje a halaye, da tunanin kashe kai / halaye.

Sauran gargaɗin Abilify da Rexulti sun haɗa da:

Akwai karuwar abubuwan da ke faruwa a cikin kwakwalwa, kamar su bugun jini ko wuce gona da iri, a cikin tsofaffi marasa lafiya wadanda ke da cutar hauka.
Idan mara lafiya ya bunkasa cututtukan ƙwayar cuta na neuroleptic (mai yuwuwa na mutuwa), nan da nan dakatar da Abilify ko Rexulti kuma saka idanu akan mai haƙuri. Alamomi da alamomin cututtukan cututtukan ƙananan ƙwayoyin cuta sun haɗa da zazzaɓi, halin tunani da ya canza, taurin kai, da bugun zuciya ko canjin hawan jini.
Idan mai haƙuri ya haɓaka dyskinesia na tardive (ba da son rai ba, maimaitaccen motsi kamar ɓacin rai ko ƙyafta ido), daina Abilify ko Rexulti idan ya dace.
Atypical antipsychotics na iya haifar da canje-canje na rayuwa, gami da karin sukarin jini / ciwon suga, karin cholesterol, da kuma karin nauyi. Kula da marasa lafiya don waɗannan canje-canje.
Abilify ko Rexulti na iya haifar da caca da cuta da wasu halaye na tilas (roƙon siyayya, yawan cin abinci, da yin jima'i). Wadannan halayen na iya buƙatar ƙaramin kashi ko dakatar da maganin.
Lura da bugun zuciya da hawan jini. Tsarin orthostatic hypotension (low blood pressure lokacin da kake tsaye) ko suma na iya faruwa.
Faduwa da ke haifar da rauni da karaya na iya faruwa. Ya kamata mai ba da kiwon lafiya ya kammala ƙididdigar haɗarin faɗuwa lokacin fara shan magani da kuma lokaci-lokaci.
Matsalolin makogwaro da buri na iya faruwa. Yi amfani da hankali a cikin marasa lafiya masu haɗari ga buri.
Canje-canje a cikin ƙididdigar ƙwayoyin farin jini na iya faruwa. Kammalallen ƙididdigar jini ya kamata a sanya ido akai-akai a cikin fewan watannin farko don marasa lafiya tare da tarihin ƙarancin ƙwayar ƙwayar ƙwayar ƙarancin jini.
Yi amfani da Abilify ko Rexulti a hankali a cikin marasa lafiya da tarihin kamawa.
Yi hankali lokacin tuki ko aiki da injina har sai kun san yadda Abilify ko Rexulti ke shafar ku.
Akwai ƙarin haɗarin kashe kansa a cikin marasa lafiya da cutar schizophrenia da bipolar cuta. Kusan kula da waɗannan marasa lafiya.
Saboda yiwuwar hulɗar miyagun ƙwayoyi, sanar da likitan ku game da duk wasu magunguna da kuka sha, duka takardun magani da na kan-kanti.
Guji zafin rana da rashin ruwa a jiki.
Sanar da mai kula da lafiyar ku idan kun yi ciki yayin shan Abilify ko Rexulti. Wadannan kwayoyi na iya haifar da extrapyramidal ko kuma bayyanar cututtuka a cikin neonate.

Tambayoyi akai-akai game da Abilify vs. Rexulti

Menene Abilify?

Abilify (aripiprazole) maganin ƙwaƙwalwar ƙwaƙwalwa ne wanda ba shi da tushe, wanda ake samu a cikin alama da kuma jituwa. Abilify ana amfani dashi don magance schizophrenia, bakin ciki (haɗe tare da maganin antidepressant), cutar bipolar I, rikicewar Tourette, bacin rai da rashin lafiyar autistic ya haifar, da tashin hankali saboda schizophrenia ko bipolar disorder.

Menene Rexulti?

Rexulti (brexpiprazole) sigar antipsychotic ne mara kyau, akwai a cikin sunan suna. Ana amfani da shi don magance ɓacin rai (a haɗe tare da maganin kashe kumburi) da sikizophrenia.

Shin Abilify da Rexulti iri ɗaya ne?

Duk magungunan biyu sunada kamanni kuma sun kasance ƙarni na biyu, antipsychotics atypical. Suna da kamanceceniya da wasu bambance-bambance, waɗanda aka zayyana a cikin bayanin da ke sama.

Shin Abilify ko Rexulti ne mafi kyau?

Akwai bayanai kaɗan da ke kwatanta magungunan biyu. Don zama FDA ta amince, duka magungunan sun sami gwajin asibiti don inganci da aminci. Mai ba ku kiwon lafiya na iya yanke shawara idan Abilify ko Rexulti ya fi muku kyau dangane da yanayin lafiyar ku, tarihin ku, da sauran magungunan da kuka sha waɗanda za su iya hulɗa da Abilify ko Rexulti.

Shin zan iya amfani da Abilify ko Rexulti yayin da nake da juna biyu?

Yaran da suka kamu da cututtukan atypical antipsychotics a lokacin watanni uku na ciki suna cikin haɗarin haɗarin bayyanar cututtukan ƙwayar cuta (wasu suna buƙatar tsawan asibiti) da kuma bayyanar cututtuka bayan bayarwa.

Akwai haɗari tare da amfani da magunguna a cikin ciki, kuma akwai haɗari ga rashin kula da yanayin lafiyar hankali kuma. Tuntuɓi mai ba da lafiyar ku don shawarar likita. Idan kana shan Abilify ko Rexulti kuma ka gano cewa kana da juna biyu, tuntuɓi mai ba ka kiwon lafiya.

Rajistar Ciki ta Kasa don Magungunan Hauka lura da sakamakon ciki a cikin marasa lafiyar da ke shan magungunan hauka yayin da suke da juna biyu.

Zan iya amfani da Abilify ko Rexulti tare da barasa?

A'a Bai kamata ku sha giya ba idan kun sha Abilify ko Rexulti. Haɗin zai iya ƙara haɗarin ɓacin rai na CNS (yawan zuga, lalacewar psychomotor, wanda zai iya haifar da haɗari) da ɓacin rai na numfashi (numfashi yana jinkiri ko ma zai iya tsayawa) da ƙananan hauhawar jini.

Shin Rexulti yana ƙara dopamine?

Atypical antipsychotics kamar Rexulti (da Abilify) suna da aiki agonist akan masu karɓa na D2 dopamine. Wani mai tsattsauran ra'ayi ya nuna cewa maganin yana ɗaure ga mai karɓa kuma yana kunna shi, amma yana da ɗan tasiri sosai (idan aka kwatanta da cikakken agonist). Don haka, waɗannan kwayoyi suna kunna masu karɓa na dopamine, wanda ke ƙaruwa matakan dopamine. Wadannan kwayoyi suna aiki a kan masu karɓar maganin serotonin.

Shin Rexulti wani maganin ƙwaƙwalwa ne?

Ee. Rexulti shine antipsychotic na ƙarni na biyu. Antiwararrun cututtukan ƙwaƙwalwa na ƙarni na biyu sababbi ne kuma suna haifar da ƙananan sakamako masu illa fiye da antipsychotics na ƙarni na farko. Baya ga Abilify da Rexulti, sauran masu ba da maganin ƙwaƙwalwa na ƙarni na biyu sun haɗa da:

Geodon (ziprasidone)
Risperdal (risperidone)
Seroquel (kuramai)
Latuda (lurasidone)
Vraylar (cariprazine)
Zyprexa (olanzapine)
Clozaril (clozapine) ya hana rarraba a cikin Amurka saboda tsananin tasirin sa.

Shin Rexulti yana taimaka damuwa?

Rexulti a halin yanzu an yarda dashi don schizophrenia da baƙin ciki (a haɗe tare da antidepressant). Daya nazarin ya kalli marasa lafiya masu fama da damuwa da alamun damuwa kuma ya sami Rexulti don taimakawa alamomin ɓacin rai (kuma an yi haƙuri sosai) a cikin marasa lafiya da damuwa. Marasa lafiya sun ɗauki Rexulti a haɗe tare da mai kwantar da hankali lokacin da mai kwantar da hankalin shi kaɗai bai taimaka ba. Tuntuɓi mai ba da lafiyar ku idan kuna da damuwa. Shi ko ita na iya ƙayyade maganin da ya dace da ku.