Losartan vs. lisinopril: Bambanci, kamance, kuma wanne ne mafi alheri a gare ku
Magunguna vs. AbokiBayanin magunguna & manyan bambance-bambance | Yanayin da aka bi | Inganci | Inshorar inshora da kwatancen farashi | Sakamakon sakamako | Hadin magunguna | Gargadi | Tambayoyi
Idan kana ɗaya daga cikin Amurkawa miliyan 103 tare hawan jini , Likitanka na iya ambaci fara maka kan magani don rage hawan jini. Losartan da lisinopril duka magungunan kwayoyi ne wadanda ake amfani dasu don magance cutar hawan jini ( hauhawar jini ). Losartan shine mai toshe mai karɓar angiotensin II (ARB) kuma lisinopril shine mai hana enzyme mai canza angiotensin (ACE inhibitor).
Dukkanin magungunan suna aiki a wani sashi na jiki da ake kira renin-angiotensin system amma ta hanyoyi daban-daban. A cikin tsarin renin-angiotensin, masu hana ACE suna toshe wani abu da ake kira angiotensin II daga yin sa. Angiotensin na II yana taƙaita jijiyoyin jini kuma yana ƙara hawan jini, don haka ta hanyar hana samar da angiotensin II, an saukar da hawan jini. ARBs sun toshe angiotensin II daga ɗaure ga masu karɓa, don haka rage saukar karfin jini.
Menene manyan bambance-bambance tsakanin losartan da lisinopril?
Losartan ARB ne, ana samun sa a cikin sunan iri da kuma na kwamfutar hannu, kamar Cozaar (ko Hyzaar lokacin da ake haɗuwa da hydrochlorothiazide, mai saurin rage ruwa a matsayin HCTZ). Hanyar da aka saba amfani dashi daga 25 MG zuwa 100 MG kowace rana.
Lisinopril shine mai hana ACE a samfuran tebur ta sunayen sunaye Prinivil ko Zestril (ko Zestoretic lokacin da yake haɗe da HCTZ). Hakanan ana samun shi azaman maganin baka wanda ake kira Qbrelis. Hanyar da aka saba amfani dashi daga 5 MG zuwa 40 MG kowace rana.
GAME: Bayanin Losartan | Bayanin Lisinopril
| Babban bambance-bambance tsakanin losartan da lisinopril | ||
|---|---|---|
| Losartan | Lisinopril | |
| Ajin magani | Angiotensin mai karɓar mai karɓa (ARB) | ACE mai hanawa |
| Alamar alama / ta kowa | Brand da janar | Brand da janar |
| Menene sunan alamar? | Cozaar Hyzaar (losartan / HCTZ) | Prinivil Zestril Qbrelis (maganin baka) Zestoretic (lisinopril / HCTZ) |
| Wani nau'i (s) ne miyagun ƙwayoyi ya shigo? | Tablet (shi kaɗai kuma a haɗe tare da HCTZ) | Tablet (shi kaɗai kuma a haɗe tare da HCTZ) |
| Menene daidaitaccen sashi? | 25 zuwa 100 MG kowace rana | 5 zuwa 40 MG kowace rana |
| Yaya tsawon maganin al'ada? | Dogon lokaci | Dogon lokaci |
| Wanene yawanci yake amfani da magani? | Manya, yara (dangane da nuni) | Manya, yara (dangane da nuni) |
Kuna son mafi kyawun farashi akan lisinopril?
Yi rajista don faɗakarwar farashin lisinopril kuma gano lokacin da farashin ya canza!
Sami faɗakarwar farashi
Yanayin da losartan vs. lisinopril yayi
Ana nuna Losartan don maganin hauhawar jini (HTN), ko hawan jini. Hakanan ana amfani dashi don rage haɗarin bugun jini ga marasa lafiya tare da hawan jini da hawan jini na hagu, kuma ana amfani dashi don magance nephropathy na masu ciwon sukari a cikin wasu marasa lafiya.
Lisinopril an nuna shi don maganin HTN, a matsayin magani na gaba a cikin cututtukan zuciya, da kuma inganta rayuwa bayan bugun zuciya.
Dukansu magungunan suna da alamun amfani da lakabi, waɗanda aka bayyana a ƙasa.
| Yanayi | Losartan | Lisinopril |
| Jiyya na hauhawar jini (HTN) | Ee | Ee |
| Rage haɗarin bugun jini a marasa lafiya tare da HTN da hawan jini na hagu (LVH) | Ee | Kashe-lakabi |
| Jiyya na nephropathy na ciwon sukari tare da haɓakar ƙwayar halitta da furotin a cikin marasa lafiya da ciwon sukari na 2 da tarihin HTN | Ee | Kashe-lakabi |
| Maganin ci gaba a cikin kula da gazawar zuciya a cikin marasa lafiya waɗanda ba su amsawa daidai ga diuretics da dijital | Kashe-lakabi | Ee |
| Jiyya na marasa lafiyar marasa lafiya a cikin awanni 24 na mummunan cututtukan zuciya (MI) don inganta rayuwa | Kashe-lakabi | Ee |
| Failurearfafa zuciya tare da rage ɓangaren fitarwa | Kashe-lakabi | Kashe-lakabi |
| Ciwon Marfan don rage saurin kumburin ciki | Kashe-lakabi | Kashe-lakabi |
| Gudanar da marasa lafiya tare da cututtukan cututtukan zuciya marasa ƙarfi wanda ba ST-ba | Kashe-lakabi | Kashe-lakabi |
| Masu karban koda | Kashe-lakabi | Off-lakabin (a cikin marasa lafiya tare da post-dashi erythrocytosis) |
| Marasa lafiya tare da cututtukan koda na yau da kullun | Kashe-lakabin (a cikin marasa lafiya na ciwon sukari) | Kashe lakabin (a cikin masu fama da ciwon sukari ko marasa ciwo) |
| Ciwon jijiyoyin zuciya | Kashe-lakabi | Kashe-lakabi |
Shin losartan ko lisinopril sun fi tasiri?
A cikin nazarin karatun 61 da ke kwatanta ARBs (gami da losartan) ga masu hana ACE (gami da lisinopril), an sami nau'ikan magungunan biyu da irin wannan tasirin na dogon lokaci akan karfin jini. Har ila yau marubutan sun kammala cewa duka nau'ikan magungunan guda biyu suna da tasiri daidai a kan mutuwa, abubuwan da suka shafi zuciya da jijiyoyin jini, manyan lamura masu cutarwa, ingancin rayuwa, da abubuwan haɗari irin su matakan lipid, ciwon sukari mellitus, da hagu na ventricular da aiki.
A cikin karami karatu na marasa lafiya da ke fama da cutar koda, losartan da lisinopril suna da irin wannan tasirin a kan aikin koda da hawan jini.
Magani mafi inganci a gare ku ya kamata likitanku ya ƙaddara ku, wanda zai iya kallon cikakken hoton yanayin lafiyar ku, tarihin ku, da sauran magungunan da kuke sha.
Verageaukar hoto da kwatancen farashin losartan vs. lisinopril
Dukkanin losartan da lisinopril suna cikin inshora da Medicare Part D a cikin sifa iri ɗaya. Za'a iya rufe nau'ikan sunan alama a mafi girman biya. Kudin aljihu don allunan 30 na losartan 100 MG na iya kaiwa daga $ 28- $ 70, kuma kuɗin Medicare Part D ya kusan $ 0- $ 13. Tare da takaddun SingleCare, farashin farashin shine $ 9- $ 16 dangane da kantin magani mai shiga. Kudin aljihun kuɗi na allunan 30 na lisinopril 10 mg kusan $ 15, kuma kuɗin Medicare Part D ya kusan $ 0- $ 7. Kuna iya adana kuɗi akan lisinopril ta amfani da katin rangwame na SingleCare ko coupon.
Gwada katin rangwame na SingleCare
| Losartan | Lisinopril | |
| Yawanci inshora ya rufe? | Ee | Ee |
| Yawanci Medicare ke rufe shi? | Ee | Ee |
| Daidaitaccen sashi | # 90, 100 MG Allunan | # 90, 20 MG Allunan |
| Hanyar biyan kuɗaɗe na Medicare | $ 0- $ 13 | $ 0- $ 7 |
| SingleCare kudin | $ 28- $ 70 | $ 9- $ 26 |
Illolin gama gari na losartan vs. lisinopril
Illolin dake tattare da cutar ta losartan sun hada da tari, jiri, jiri na sama, gajiya, da gudawa.
Sakamakon illa na yau da kullun na lisinopril sun hada da tari, jiri, ciwon kai, gajiya, da gudawa.
Sauran sakamako masu illa na iya faruwa. Tuntuɓi ƙwararren masanin kiwon lafiya don cikakken jerin abubuwan illa.
| Losartan | Lisinopril | |||
| Tasirin Side | Ana amfani? | Mitar lokaci | Ana amfani? | Mitar lokaci |
| Tari | Ee | 17-29% | Ee | 3.5-69% |
| Dizziness | Ee | 3% | Ee | 5.4% |
| Babban numfashi kamuwa da cuta | Ee | 8% | Ee | 2.1% |
| Cutar hanci | Ee | kashi biyu | Ee | 0.4% |
| Ciwon baya | Ee | kashi biyu | Ba | - |
| Gajiya | Ee | > 4% | Ee | 2.5% |
| Gudawa | Ee | > 4% | Ee | 2.7% |
| Ciwan | Ee | Ba a ruwaito ba | Ee | kashi biyu |
| Ciwon kai | Ee | Ba a ruwaito ba | Ee | 5.7% |
Source: DailyMed (losartan) , DailyMed (lisinopril)
Magungunan ƙwayoyi na losartan vs. lisinopril
Bai kamata a yi amfani da Losartan ko lisinopril tare da sinadarin potassium ko wasu magunguna da ke kara sinadarin potassium ba (kamar su masu saurin yaduwar sinadarin potassium), saboda hatsarin cutar hyperkalemia. Bugu da ƙari, ka tambayi likitanka game da furotin a cikin abincinka kuma idan ya kamata ka guji wadataccen abinci mai ƙoshin potassium da maye gurbin gishiri waɗanda ke ɗauke da sinadarin potassium.
Kada a yi amfani da NSAIDs (marasa maganin cututtukan cututtukan steroid) don haɗuwa da losartan ko lisinopril, saboda haɗuwa na iya haifar da raunin koda ko gazawar koda.
Bai kamata ayi amfani da Losartan ko lisinopril a hade tare da wani mai hana ACE ba, ARB, ko Tekturna (aliskiren) saboda haduwar na kara saurin kamuwa da cutar hawan jini, yawan sinadarin potassium, suma, lalacewar koda, ko gazawar koda.
Tuntuɓi mai ba da lafiyar ku don cikakken jerin ma'amala da ƙwayoyi.
| Drug | Ajin Magunguna | Losartan | Lisinopril |
| Potassium | Wutar lantarki | Ee | Ee |
| Midamor (amiloride) Aldactone (spironolactone) Dyrenium (triamterene) Inspra (eplerenone) | Turawa mai rage sanadarin potassium | Ee | Ee |
| Asfirin Motrin, Advil (ibuprofen) Aleve (naproxen) Mobic (meloxicam) Celebrex (celecoxib) Relafen (nabumetone) | NSAIDs | Ee | Ee |
| Vasotec (enalapril) Lotensin (benazepril) Accupril (quinapril) Altace (ramipril) | Masu hana ACE | Ee | Ee |
| Diovan (valsartan) Edarbi Kai hari (candesartan) Avapro (irbesartan) Micardis (telmisartan) Benicar (olmesartan) | ARBs | Ee | Ee |
| Tekturna (aliskiren) | Renin mai hanawa | Ee | Ee |
| Lithium | Antimanic wakili | Ee | Ee |
Gargadi na losartan da lisinopril
Losartan da lisinopril duk sun zo da gargadin dambe, wanda shine gargadi mafi karfi kamar yadda FDA ta bukata. Magunguna (kamar losartan da lisinopril) waɗanda ke aiki a kan tsarin renin-angiotensin na iya haifar da mummunan rauni na tayi / nakasar haihuwa ko mutuwa kuma ya kamata a dakatar da shi da zarar an kafa ciki.
Sauran gargadin da suka shafi losartan da lisinopril:
- Marasa lafiya da ke bushewa ko shan diuretics na iya haifar da ƙananan jini (hypotension).
- Canje-canje a cikin aikin koda, gami da ƙarancin ƙwayar koda, na iya faruwa. Haɗarin ya fi girma a cikin marasa lafiya da ke fama da matsalar koda ko kuma rashin ƙarfin zuciya. Wadannan marasa lafiya bazai zama dan takarar don mai hana ACE ba ko ARB. Idan aka fara daya daga cikin wadannan kwayoyi, ya kamata a kula da aikin koda.
- Yakamata a kula da sinadarin potassium.
Lisinopril yana da ƙarin faɗakarwa:
- Akwai yuwuwar yin wani aiki na rashin lafiyar (rashin lafiyan mai tsanani), gami da angioedema (kumburi) na fuska, tsautsayi, leɓɓa, harshe, glottis, da / ko maƙogwaro. Wannan halayen na iya faruwa kowane lokaci yayin jiyya. Angioedema da ke da alaƙa da edema na laryngeal na iya mutuwa. Inda akwai sa hannu ga harshe, glottis ko maƙogwaro, da alama na iya haifar da toshewar hanyar iska, magani na gaggawa ya zama dole. Lisinopril yakamata a dakatar dashi idan waɗannan halayen sun faru.
- Akwai ƙananan haɗarin matsalolin hanta; hanta enzymes ya kamata a kula.
- Saboda lalacewar wani abu da ake kira bradykinin, busasshen tari na iya faruwa. Da zarar an dakatar da maganin, tari ya kamata ya tafi.
Tambayoyi akai-akai game da losartan da lisinopril
Menene losartan?
Losartan shine mai toshe maganin karbawar angiotensin wanda ke taimakawa rage saukar karfin jini. Hakanan za'a iya amfani dashi don wasu yanayi daban-daban, waɗanda aka zayyana a sama.
Menene lisinopril?
Lisinopril shine mai hana ACE wanda ke taimakawa rage saukar karfin jini. Hakanan ana amfani dashi don wasu yanayin kiwon lafiya, waɗanda aka zayyana a sama.
Shin losartan vs. lisinopril iri daya ne?
Kodayake duka magunguna suna aiki akan tsarin renin-angiotensin, suna aiki akan bangarori daban daban na tsarin, amma duka magungunan suna saukar da hawan jini kuma ana amfani dasu don wasu yanayin zuciya ko koda. Hakanan suna da sauran bambance-bambance a cikin allurai, gargaɗi, da kuma farashin.
Sauran masu hana ACE na yau da kullun (kamar lisinopril) wataƙila kun ji sun haɗa da Lotensin (benazepril), Vasotec (enalapril), Accupril (quinapril), da Altace (ramipril).
Sauran ARBs (kamar losartan) wataƙila kun ji sun haɗa da Edarbi (azilsartan - babu wadatar samuwa), Atacand (candesartan), Avapro (irbesartan), Micardis (telmisartan), Diovan (valsartan), da Benicar (olmesartan).
Shin losartan ko lisinopril ne mafi kyau?
Nazarin ya nuna ARBs kamar losartan da masu hana ACE kamar lisinopril don samun irin wannan tasirin. Tuntuɓi mai ba da lafiyar ku don ganin ko ɗayan waɗannan magunguna ya dace da ku.
Shin zan iya amfani da losartan ko lisinopril yayin da nake da juna biyu?
Bai kamata a sha Losartan ko lisinopril yayin daukar ciki ba. Duk kwayoyi biyun suna da haɗari sosai ga ɗan tayi mai tasowa kuma suna iya haifar da lahani na haihuwa ko ma mutuwa ga ɗan tayi. Idan kana shan losartan ko lisinopril kuma ka gano cewa kana da juna biyu, to ka tuntubi likitanka kai tsaye.
Zan iya amfani da losartan ko lisinopril tare da barasa?
Shan barasa yayin shan losartan ko lisinopril na iya kara yawan dima jiki, ko kuma ya shafi hawan jininka ko wani yanayin lafiya. Tuntuɓi likitanka game da amfani da barasa tare da losartan ko lisinopril.
Shin ya kamata in dauki lisinopril da losartan tare?
A'a. Kodayake ana amfani da wasu magungunan hawan jini a hade (kamar su losartan ko lisinopril a hade tare da mai maganin kurji), bai kamata a dauki lisinopril da losartan a hade ba. Yin hakan na kara barazanar kamuwa da cutar hawan jini, yawan potassium, da rauni ga kodan, wanda ka iya zama mai tsananin gaske ko kuma ya zama ajalin mutum.
Shin losartan shine mai hana ACE ko beta toshe?
Losartan shine mai toshe mai karɓar angiotensin. Ba mai hana ACE bane ko mai hana beta.
Shin losartan yana haifar da raunin sakamako fiye da lisinopril?
Dukansu magungunan suna da illa iri ɗaya, kodayake lisinopril na iya haifar da tari mai bushe kuma yana da haɗarin angioedema (rashin lafiyan mai saurin faruwa). Tuntuɓi ƙwararren likitanku don cikakken jerin abubuwan illa.
