Eliquis vs. Xarelto: Bambanci, kamance, kuma wanene ya fi muku
Magunguna vs. AbokiBayanin magunguna & manyan bambance-bambance | Yanayin da aka bi | Inganci | Inshorar inshora da kwatancen farashi | Sakamakon sakamako | Hadin magunguna | Gargadi | Tambayoyi
Eliquis da Xarelto su ne nau'ikan magunguna guda biyu wadanda ake amfani dasu don magance cututtukan ciwan jini da yawa. Dukansu magungunan kwayoyi ne wadanda aka kirkiresu a cikin wani rukuni na magunguna da ake kira factor Xa inhibitors Suna aiki ne ta hanyar toshe sinadarin Xa, wanda ke samar da thrombin, wani sinadari ne da ya dace wajen samar da gudan jini. Ta hanyar toshe sinadarin Xa, magungunan suna rage yawan daskarewa. Ci gaba karantawa a ƙasa don ƙarin koyo game da Eliquis da Xarelto.
Menene manyan bambance-bambance tsakanin Eliquis da Xarelto?
Eliquis (apixaban) da Xarelto (rivaroxaban) sune NOACs (maganin rigakafin maganin gargajiya), waɗanda sune rukuni na sababbin masu sikanin jini. Ana kuma san su da DOAC (maganin kai tsaye na maganin hana yaduwar jini). Ba kamar Coumadin (warfarin) ba, mashahuri kuma tsoffin maganin rigakafi, marasa lafiya da ke shan Eliquis ko Xarelto ba sa buƙatar gwajin jini na yau da kullun don lura da matakan. Dukansu Eliquis da Xarelto an san su da factor Xa inhibitors, amma suna da wasu bambance-bambance.
Eliquis da Xarelto duka FDA sun amince dasu don amfani da takardar sayan magani kuma ana samun su cikin sunan kawai. Babu kwayar halitta har yanzu don kowane magani; Koyaya, yakamata Eliquis ya kasance za'a samu nan bada jimawa ba . Eliquis ne ya kera ta Bristol-Myers Squibb. Xarelto ne aka kirkira ta Janssen Pharmaceuticals. Dukansu magunguna suna amfani da manya, kuma sashin ya bambanta ta hanyar nuni.
| Babban banbanci tsakanin Eliquis da Xarelto | ||
|---|---|---|
| Eliquis | Xarelto | |
| Ajin magani | Factor Xa mai hanawa | Factor Xa mai hanawa |
| Alamar alama / ta kowa | Alamar | Alamar |
| Menene sunan jimla? | Apixaban | Rivaroxaban foda |
| Wani nau'i (s) ne miyagun ƙwayoyi ya shigo? | Tablet, Starter fakitin | Tablet, Starter fakitin |
| Menene daidaitaccen sashi? | 2.5 MG ko 5 MG sau biyu a rana Sashi ya bambanta ta hanyar nuni | 10 MG zuwa 20 MG sau ɗaya a rana Sashi ya bambanta ta hanyar nuni |
| Yaya tsawon maganin al'ada? | Ya bambanta | Ya bambanta |
| Wanene yawanci yake amfani da magani? | Manya | Manya |
Kuna son mafi kyawun farashi akan Eliquis?
Yi rajista don faɗakarwar farashin Eliquis kuma gano lokacin da farashin ya canza!
Sami faɗakarwar farashi
Yanayin da Eliquis da Xarelto suka kula da shi
Eliquis da Xarelto suna da alamomi da yawa da suke daidai-don rage haɗarin bugun jini da embolism a cikin marasa lafiya da ke fama da cutar sanyin jiki (AFib, ko bugun zuciya mara kyau), hana ƙwanƙwasa mai zurfin jijiyoyin jini (DVT) a cikin marasa lafiyar da suka sami maye gurbin gwiwa ko gwiwa, bi da DVT, bi da PE, kuma don rage haɗarin sake maimaita DVT ko PE bayan bin magani na farko.
Bugu da ƙari, Xarelto yana da ƙarin alamomi biyu. Xarelto na iya hana cututtukan ƙwaƙwalwa (VTE) da mutuwa mai nasaba da VTE. Xarelto za a iya ba da umarnin a lokacin asibiti da kuma bayan fitarwa a cikin manya marasa lafiya waɗanda ke cikin haɗari ga rikitarwa saboda ƙuntataccen motsi da sauran abubuwan haɗarin. Koyaya, bai kamata a sanya Xarelto ga marasa lafiya waɗanda ke cikin haɗarin zub da jini ba. Ana amfani da Xarelto tare da asfirin don rage haɗarin manyan abubuwan da suka shafi zuciya da zuciya kamar mutuwa, bugun zuciya, da bugun jini ga marasa lafiya da ke fama da cutar jijiyoyin jijiyoyin jiki (CAD) ko kuma jijiyoyin jijiyoyin jiki (PAD).
| Yanayi | Eliquis | Xarelto |
| Rage haɗarin bugun jini da embolism a cikin marasa lafiya tare da fibrillation na atrial nonvalvular | Ee | Ee |
| Prophylaxis na zurfin jijiyoyin jini (DVT), wanda zai iya haifar da embolism na huhu (PE), a cikin marasa lafiyar da aka yi wa tiyata a gwiwa ko gwiwa | Ee | Ee |
| Jiyya na DVT | Ee | Ee |
| Jiyya na PE | Ee | Ee |
| Rage haɗarin maimaita DVT da PE bayan farawar farko | Ee | Ee |
| Prophylaxis na cututtukan ƙwaƙwalwa (VTE) da mutuwar da ke da alaƙa da VTE a yayin asibiti da fitowar asibiti bayan fitowar a cikin marasa lafiya tsofaffi da aka shigar da su ga wani mummunan rashin lafiya na likita waɗanda ke cikin haɗarin rikitarwa na thromboembolic saboda ƙuntataccen motsi / sauran abubuwan haɗari kuma ba cikin haɗarin jini ba | Ba | Ee |
| A haɗe tare da asfirin, don rage haɗarin manyan abubuwan da suka shafi zuciya da jijiyoyin jini: mutuwar zuciya da jijiyoyin jini, infarction na myocardial (MI) da bugun jini a cikin marasa lafiya waɗanda ke fama da cututtukan jijiyoyin jijiyoyin jiki (CAD) ko cututtukan jijiyoyin jiki (PAD) | Ba | Ee |
Shin Eliquis ko Xarelto sun fi tasiri?
ZUWA nazari da zane-zane na Eliquis da Xarelto na mummunan cututtukan ƙwaƙwalwa (VTE) sun yanke hukunci cewa duka kwayoyi sunyi tasiri iri ɗaya amma Eliquis na iya zama mafi aminci. Marasa lafiya da aka yi wa magani tare da Xarelto sun sami ƙarin zub da jini-manya da ƙanana.
Wani nazarin ya sake nazarin Eliquis da Xarelto, da kuma Pradaxa (wani sabon maganin rigakafin kwayoyi) da Coumadin (warfarin, tsoffin maganin rigakafi). Mawallafa sun yanke shawarar cewa Eliquis yana da inganci mafi inganci, aminci, da kuma haƙuri.
Mafi kyawun magani a gare ku kawai mai ba da sabis na kiwon lafiya ne zai iya ƙayyade ku, wanda zai iya yin la'akari da cikakken hoto na yanayin lafiyar ku, tarihin lafiyar ku, da sauran magungunan da kuka sha waɗanda zasu iya hulɗa da Eliquis ko Xarelto.
Kuna son mafi kyawun farashi akan Xarelto?
Yi rajista don faɗakarwar farashin Xarelto kuma gano lokacin da farashin ya canza!
Sami faɗakarwar farashi
Verageaukar hoto da kwatancen farashi na Eliquis vs. Xarelto
Eliquis yawanci yana rufe inshora da Medicare Sashe na D, amma masu biyan kuɗi sun bambanta sosai. Takaddun tsarin Eliquis na kwatankwacin tanadin wata ɗaya (allunan 60 na 5 MG) zaikai kusan $ 700 idan ka biya aljihu. Kuna iya amfani da sayan katin SingleCare Eliquis a ƙasa da $ 450.
Xarelto yawanci ana rufe shi ta inshora da Medicare Sashe na D, amma masu biyan kuɗi sun bambanta. Takaddun magani na Xarelto na yau da kullun don samar da wata guda (30 allunan 20 MG) zai kai kimanin $ 620 a farashin farashi. Kuna iya amfani da coupon SingleCare don siyan Xarelto akan kusan $ 430.
| Eliquis | Xarelto | |
| Yawanci inshora ke rufe shi? | Ee | Ee |
| Yawanci an rufe shi ta Medicare Part D? | Ee | Ee |
| Daidaitaccen sashi | # 60, allunan mg 5 | # 30, 20 MG allunan |
| Hankula Medicare Part D copay | $ 19- $ 541 | $ 19- $ 508 |
| SingleCare kudin | $ 447- $ 483 | $ 428- $ 471 |
Illolin yau da kullun na Eliquis vs. Xarelto
Illolin dake tattare da magungunan duka sunada alaƙa da zub da jini, kamar zub da jini, rikicewar jini (jini), jini a cikin fitsari, ko zubda jini. Halin tasirin sakamako masu illa na jini na iya bambanta. A wasu lokuta da ba safai ba, zubar jini na iya zama mai tsanani ko ma mai barazanar rai.
Sauran illolin da ka iya faruwa tare da Eliquis sun haɗa da gajiya, rashi ƙarfi, rauni, ƙarancin numfashi, da jiri.
Sauran cututtukan da zasu iya faruwa tare da Xarelto sun hada da ciwon ciki ko na baya, gajiya, jiri, kaikayi, damuwa, damuwa, da / ko rashin bacci.
Wannan ba cikakken lissafin sakamako bane. Tuntuɓi mai ba da lafiyar ku don ƙarin bayani game da mummunan halayen Eliquis da Xarelto.
| Eliquis | Xarelto | |||
| Tasirin Side | Ana amfani? | Mitar lokaci | Ana amfani? | Mitar lokaci |
| Zuban jini | Ee | Ya bambanta | Ee | Ya bambanta |
| Ciwon ciki | Ee | Ba a sani ba | Ee | 2.7% |
| Gajiya | Ee | Na kowa | Ee | 1.7% |
| Rashin kuzari | Ee | Na kowa | Ba | - |
| Rashin ƙarfi | Ee | Na kowa | Ba | - |
| Rashin numfashi | Ee | Na kowa | Ba | - |
| Ciwon baya | Ba | - | Ee | 2.9% |
| Dizziness | Ee | Ba a sani ba | Ee | 2.2% |
| Tashin hankali | Ba | - | Ee | 1.4% |
| Ciwan | Ee | Na kowa | Ba | - |
| Bacin rai | Ba | - | Ee | 1.2% |
| Rashin bacci | Ba | - | Ee | 1.6% |
| Itching | Ee | <1% | Ee | 2.2% |
Source: DailyMed ( Eliquis ), Samfurin Monograph ( Eliquis ,, DailyMed ( Xarelto )
Magungunan ƙwayoyi na Eliquis da Xarelto
Eliquis da Xarelto suna hulɗa tare da wasu ƙwayoyi waɗanda enzyme ɗaya ke sarrafa su. Lokacin da ake amfani da magungunan hana enzyme tare da Eliquis ko Xarelto, matakan Eliquis ko Xarelto a jikinka zai ƙaru, wanda zai sa ku cikin haɗarin zubar jini. Idan dole ne ku ɗauki wannan haɗin magungunan, mai yiwuwa likitanku zai rage adadin ku na Eliquis ko Xarelto yayin duka magunguna biyu.
A gefe guda kuma, idan aka dauki masu amfani da enzyme tare da Eliquis ko Xarelto, akwai mu'amala inda wadannan kwayoyi suke sa Eliquis ko Xarelto suyi saurin narkewa, kuma ba za ku sami isasshen kwayar Eliquis ko Xarelto ba.
Hakanan, yin amfani da Eliquis ko Xarelto tare da wasu magungunan hana yaduwar jini, magungunan hana daukar ciki, NSAIDs (magungunan da ba na steroid ba ne), da kuma wasu magungunan kwantar da hankali na iya kara yiwuwar zub da jini.
Wannan ba cikakke bane game da ma'amala da ƙwayoyi. Tuntuɓi mai ba da lafiyar ku don ƙarin bayani.
| Drug | Ajin Magunguna | Eliquis | Xarelto |
| Itraconazole Ketoconazole Ritonavir | Inhibananan masu hana enzyme (CYP3A4 da P-gp) | Ee | Ee |
| Carbamazepine Phenytoin Rifampin St. John’s Wort | Cearfin enzyme masu ƙarfi (CYP3A4 da P-gp) | Ee | Ee |
| Citalopram Desvenlafaxine Duloxetine Escitalopram Fluoxetine Fluvoxamine Paroxetine Sertraline Venlafaxine | SSRIs da magungunan SNRI | Ee | Ee |
| Clopidogrel Enoxaparin Heparin NSAIDs (dogon lokaci) ● Asfirin Up Ibuprofen Lo Meloxicam Um Nabumetone Pro Naproxen Warfarin (coumadin) | Anticoagulants da antiplatelets | Ee | Ee |
Gargadi na Eliquis da Xarelto
Eliquis da Xarelto suna da gargadin (akwatin baƙar fata), wanda shine gargaɗi mafi ƙarfi da FDA ke buƙata. Sauran gargaɗin sun haɗa da:
- Tsayar da Eliquis ko Xarelto da wuri yana ƙara haɗarin abin da ya shafi daskarewa.
- Epidural ko spinal hematoma na iya faruwa a cikin marasa lafiya waɗanda ke karɓar neuraxial (tsakanin vertebrae) maganin sa barci ko hujin kashin baya. Hemoma zai iya haifar da inna na dogon lokaci ko na dindindin. Haɗarin ya fi girma a cikin marasa lafiya da keɓaɓɓun catheters, marasa lafiya da ke shan wasu magunguna waɗanda ke shafar gudan jini, marasa lafiya da tarihin rauni / maimaita huhu, da / ko marasa lafiya da tarihin nakasar kashin baya ko tiyata. Dole ne a kula da marasa lafiya akai-akai don alamomi / alamomi na nakasar jijiyoyi (suma / rauni na kafafu, matsalolin hanji / mafitsara), kuma idan duk wata matsala ta faru, mai haƙuri ya nemi gaggawa na gaggawa.
- Zubar jini na iya faruwa kuma zai iya zama mai tsanani (babbar zub da jini) ko kuma na iya yin ajalin mutum. Yin amfani da Eliquis ko Xarelto tare da wasu ƙwayoyi (masu ba da magani, magunguna, NSAIDs, SSRI da SNRI antidepressants) suna ƙara haɗarin zubar jini. Marasa lafiya tare da zub da jini ya kamata neman gaggawa na likita. Ya kamata a dakatar da maganin a cikin marasa lafiya tare da zubar da jini mai aiki.
- Akwai wakili na juyawa, don juya sakamakon tasirin hana Ha.
- Eliquis ko Xarelto ba da shawarar a cikin marasa lafiya tare da bawul na zuciya.
- Eliquis ko Xarelto ba a ba da shawarar azaman madadin heparin don maganin farko na marasa lafiyar PE waɗanda ke da rashin lafiyar hemodynamic (gigicewa / bugun zuciya).
- Kada a yi amfani da Eliquis ko Xarelto a cikin marasa lafiya masu fama da cutar antiphospholipid (APS) sau uku-uku saboda haɗarin samun daskarewa.
- Idan kana da matsalolin hanta ko koda, yi magana da mai ba da lafiyar ka kafin ɗaukar Eliquis ko Xarelto.
Amfani da ciki:
- Akwai iyakantattun bayanai kan amfani da Eliquis ko Xarelto a cikin ciki. Jiyya tare da Eliquis ko Xarelto na iya ƙara haɗarin zub da jini yayin duka ciki da haihuwa, da ƙara haɗarin zubar da jini a tayin / jariri. Yin amfani da Eliquis ko Xarelto yayin nakuda ko haihuwa a cikin matan da ke karɓar ƙwayar cuta na iya haifar da epidural ko spinal hematoma Za a iya amfani da maganin ƙwanƙwasa na gajeren lokaci idan an buƙata. Tuntuɓi OB-GYN ɗinka game da amfani da Eliquis ko Xarelto yayin ɗaukar ciki. Gabaɗaya, ana amfani da miyagun ƙwayoyi ne kawai idan fa'idodi sun fi haɗari (alal misali, a cikin wasu mata masu haɗari masu haɗari), kuma tare da lura da hankali. Idan kana amfani da Eliquis ko Xarelto kuma gano cewa kai kake mai ciki , nemi shawarar OB-GYN don jagora.
Tambayoyi akai-akai game da Eliquis vs. Xarelto
Menene Eliquis?
Eliquis wani suna ne mai suna anticoagulant (mai kara jini) wanda ake amfani dashi don hana ko magance daskarewar jini.
Menene Xarelto?
Xarelto shine sunan da ake kira anticoagulant, kuma yana taimakawa wajen hana ko magance daskarewar jini.
Shin Eliquis da Xarelto iri daya ne?
Eliquis da Xarelto duka sanannu ne a matsayin masu haɓaka masu haɓaka Xa. Suna da kama sosai, amma ba daidai bane. An bayyana bambance-bambance a sama. Sauran abubuwan masu hana Xa sune Pradaxa (dabigatran), Arixtra (fondaparinux), Savaysa (edoxaban), da Bevyxxa (betrixaban).
Shin Eliquis ko Xarelto sun fi kyau?
Nazarin (duba sama don cikakkun bayanai) sun nuna cewa Eliquis da Xarelto suna da tasiri iri ɗaya, ko kuma Eliquis na iya zama mai ɗan tasiri kaɗan. Eliquis kamar yana da ƙananan haɗarin zubar jini fiye da Xarelto. Tambayi likitan ku idan Eliquis ko Xarelto sun dace da ku.
Zan iya amfani da Eliquis ko Xarelto yayin da nake da juna biyu?
Kullum, Eliquis da Xarelto ba'a amfani dasu a cikin ciki. Koyaya, wasu keɓaɓɓu na iya faruwa a cikin wasu marasa lafiya waɗanda ke cikin haɗarin ƙwanƙwasa. Tuntuɓi mai ba da lafiyar ku.
Zan iya amfani da Eliquis ko Xarelto da barasa?
Barasa na iya sirirce jini. Idan ka ɗauki Eliquis ko Xarelto ka sha barasa, wannan na iya ƙara haɗarin zubar jini. Hakanan, barasa na iya tsananta wasu yanayin rashin lafiya. Kuna iya tambayar likitan ku idan lafiyayyen abin sha ne, da kuma nawa, tare da magungunan da kuke sha da kuma yanayin lafiya (s) da kuke da shi.
Shin Xarelto ya fi Eliquis rahusa?
Don wadatarwar wata ɗaya, farashin Xarelto da farashin Eliquis sun yi kama sosai. Farashin Eliquis da Xarelto tare da takaddar SingleCare fara daga $ 447 da $ 428. Yakamata a samu wadataccen abu don Eliquis nan bada jimawa ba
Mene ne mafi amincin sikan jini don amfani?
Magungunan jini na da lafiya idan aka yi amfani da su kamar yadda aka tsara. Koyaya, tare da kowane mai yankan jini, akwai haɗarin zubar jini, koda babba ne ko jini mai barazanar rai. Hakanan masu rage jini suna iya ma'amala da wasu magunguna. Tuntuɓi mai ba da lafiyar ku don gano wane ƙwayar jini ne ya fi dacewa da ku.
Shin Eliquis yana shafar hanta?
Kasa da 1% na marasa lafiya akan Eliquis a cikin gwajin asibiti yana da gwajin hanta mara kyau. Ya kamata ku sanar da likitanku kafin shan Eliquis ko Xarelto idan kuna da matsalolin hanta.
