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Lovenox vs. heparin: Bambanci, kamance, kuma wanne ne mafi alheri a gare ku

Magunguna vs. Aboki

Za'a iya rubuta maka Lovenox (enoxaparin) ko heparin don magance ko hana daskarewar jini. Lovenox da heparin duka magungunan allura ne waɗanda suke ɓangare na babban rukunin magunguna da ake kira anticoagulants. A matsayinsu na masu hana yaduwar jini, ko masu rage jini, Lovenox da heparin suna taimakawa wajen magancewa da kuma hana thrombosis mai zurfin ciki (DVT) da embolism embolism (PE).

Dukansu Lovenox da heparin suna da irin wannan aikin aikin. Suna aiki ne ta hanyar ɗaura ga ƙaramin kwayar sunadaran da ake kira antithrombin da kuma toshe ayyukan thrombin, factor Xa, da sauran enzymes masu alaƙa da ciwan jini. Kodayake ana rarraba Lovenox azaman ƙananan ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta (LMWH), ba daidai yake da heparin na yau da kullun ba.

Menene manyan bambance-bambance tsakanin Lovenox da heparin?

Lovenox shine sunan alama don enoxaparin. LMWH ce ta Sanofi-Aventis. Lovenox ana yi masa allura a ƙarƙashin hanya (a ƙarƙashin fata), kuma ana samun sa a ɗoki biyu: 100 mg / ml da 150 mg / ml.

Sanannun sirinji na Lovenox sunzo da ƙarfi iri-iri kuma ana samun su a cikin kwayoyi masu yawan magani 300 mg / 3 ml.

Lovenox yana da rabin rabi na kusa 4.5 zuwa 7 hours bayan gudanarwa, kuma illolinsa na magance jini ya wuce awa 12. Saboda tsawon rabin rayuwarsa da tasirin tasirinsa, Lovenox baya buƙatar cikakken kulawa ko kulawa don amfani dashi.

Heparin, wanda aka fi sani da heparin na yau da kullun ko heparin da ba a raba shi ba (UFH), allura ce ta gama gari. Heparin kuma yana da sunaye kamar Hep-Lock.

Heparin yawanci ana yin shi ta jijiyoyin jini (ta wata jijiya) ko kuma ayi subcutaneously (a karkashin fata). Ana samuwa a cikin nau'i-nau'i guda-nau'i da nau'i-nau'i masu yawa tare da ƙarfafan ƙarfi waɗanda na iya haɗawa da rukunin USP 1,000 / ml, 5,000 USP raka'a / ml, da 10,000 USP raka'a / ml.

Idan aka kwatanta da Lovenox, heparin yana da ƙaramin rabin rai na 0.5 zuwa awanni 2. Heparin yana buƙatar a ba shi sau da yawa fiye da Lovenox, kuma yawanci ana gudanar da shi a cikin asibiti. Hanyoyin maganin ciwon hanta na heparin suna buƙatar kulawa saboda tasirinsa yafi rashin tabbas fiye da ƙananan ƙwayar heparin.

Babban bambanci tsakanin Lovenox da heparin
	Lovenox	Heparin
Ajin magani	Anticoagulant	Anticoagulant
Alamar alama / ta kowa	Nau'i da nau'ikan sigar akwai	Nau'i da nau'ikan sigar akwai
Menene sunan gama-gari?	Enoxaparin	Heparin shine sunan suna na Heparin Sodium ADD-Vantage
Wani nau'i (s) ne miyagun ƙwayoyi ya shigo?	Magani ga allura	Magani ga allura
Menene daidaitaccen sashi?	40 MG sau ɗaya sau ɗaya a kowace rana. Sashi na iya bambanta dangane da yanayin da ake bi.	Rakunan 5000 subcutaneously kowane takwas zuwa 12 hours. Sashi na iya bambanta dangane da yanayin da ake bi.
Yaya tsawon maganin al'ada?	7 kwanakin, fiye ko dependingasa dangane da yanayin da ake bi	7 kwanakin, fiye ko dependingasa dangane da yanayin da ake bi
Wanene yawanci yake amfani da magani?	Manya, yara, da jarirai	Manya, yara, da jarirai

Kuna son mafi kyawun farashi akan Lovenox?

Yi rajista don faɗakarwar farashin Lovenox kuma gano lokacin da farashin ya canza!

Sami faɗakarwar farashi

Yanayin da Lovenox da heparin suka bi da shi

Dukansu Lovenox da heparin an yarda da su a Amurka don maganin ƙwaƙwalwar ƙwaƙwalwa (VTE) , yanayin da ya hada da zurfin jijiyoyin jini da huhu na huhu. Jigilar jini na iya zama sau da yawa a kafafu ko hannu (zurfin jijiyoyin jini / DVT) kuma suna iya tafiya zuwa huhu inda suke zama a cikin jijiyoyin jini (embolism embolism / PE).

Lovenox da heparin suma ana amfani dasu don rigakafin daskarewar jini, musamman bayan tiyata kamar tiyatar gwiwa ko tiyatar maye. Kwanciya kwanciyar hankali bayan tiyata na ɗaya daga cikin mawuyacin haɗari ga daskarewar jini. Sauran abubuwan da ke tattare da hadari ga daskarewar jini sun hada da tarihin dangi na rikicewar daskarewar jini, ciki, kiba, shan sigari, da kuma cutar kansa.

Heparin kuma an yarda dashi don hanawa da magance daskarewar jini wanda zai iya samuwa daga atrial fibrillation . Akasin haka, an yarda da Lovenox don magancewa da hana rikice-rikice a cikin mutanen da ke fuskantar wasu nau'ikan ciwo na kirji (angina mara ƙarfi) da bugun zuciya (baƙuwar ƙwayar cuta ta Q-wave).

Yanayi	Lovenox	Heparin
Jiyya da rigakafin cutar sanyin jiki	Ee	Ee
Jiyya da rigakafin daskarewar jini bayan tiyata	Ee	Ee
Rigakafin da maganin rikitarwa daga ɓarna	Kashe-lakabi	Ee
Rigakafin rikitarwa daga rashin kwanciyar hankali da bugun zuciya	Ee	Kashe-lakabi

Shin Lovenox ko heparin ya fi tasiri?

Lovenox da heparin duk suna da tasiri don magancewa da kuma hana daskarewar jini. Suna aiki ta hanyoyi iri ɗaya don ba da damar jini ya gudana cikin yardar kaina. Aunar magani ɗaya a kan ɗayan ya dogara da farashi, sakamako masu illa, da gudanarwa.

Idan aka kwatanta da heparin, Lovenox yana da tsawon rabin rai. Ma'ana, yana daɗewa kuma ana iya gudanarwa sau ɗaya kowace rana. Yin amfani da allurai ya fi tsinkaya tare da Lovenox, kodayake marasa lafiya masu nauyin jiki suna bukatar yawan allurai, kamar allura guda biyu sau biyu a rana.

A cikin meta-bincike daga Jaridar Thrombosis da Haemostasis , enoxaparin da heparin marasa rarrabawa an gwama su don hana daskarewar jini a marasa lafiyar asibiti. Gwaje-gwajen asibiti guda huɗu sun haɗa a cikin meta-bincike kuma sun kimanta duka marasa lafiya 3,600. Sakamako ya gano cewa, idan aka kwatanta da heparin, enoxaparin ya rage ƙwanƙwasa jini ba tare da haɓaka haɗarin babban zubar jini ba.

Caveaya daga cikin faɗakarwa don amfani da Lovenox shine cewa ana buƙatar daidaita sashinta a cikin marasa lafiya tare da gazawar koda. In ba haka ba, akwai ƙarin haɗarin zubar jini. A cikin aikin asibiti, an fi son heparin don mutanen da ke fama da cutar koda.

Likitanku zai rubuta mafi kyawun maganin hana yaduwar cutar don yanayinku. Mafi ƙarancin maganin ƙwayar cuta za a ƙaddara bisa ga tarihin lafiyar ku gaba ɗaya.

Verageaukar hoto da kwatancen farashi na Lovenox vs. heparin

Yawancin Medicare da tsare-tsaren inshora zasu rufe Lovenox. Koyaya, inshora zai iya ɗaukar nauyin Lovenox na yau da kullun, kuma ƙila baza su iya biyan cikakken kuɗin ba. Matsakaicin farashin sayarwa na Lovenox yana kusan $ 380. Idan kana sayen allurar Lovenox don amfanin gida daga kantin magani, zaka iya amfani da katin Lovenox SingleCare don adana kuɗi. Maimakon biyan cikakken farashi don Lovenox, zaka iya biyan ƙasa da $ 75 don sirinji guda 10 da aka cika.

Heparin yawanci ana rufe shi ne ta hanyar Medicare da tsare-tsaren inshora. Hakanan yana da tsada fiye da Lovenox. Duk da haka, matsakaicin farashin heparin shine $ 120, ya dogara da yawa da sashi. Tare da takaddun shaida na SingleCare, zaka iya samun sa ƙasa da $ 50 a cikin kantunan shiga.

	Lovenox	Heparin
Yawanci inshora ya rufe?	Ee	Ee
Yawanci an rufe shi ta Medicare Part D?	Ee	Ee
Daidaitaccen sashi	40 MG a sauƙaƙe sau ɗaya kowace rana (yawan 10)	Rakunan 5000 subcutaneously kowane takwas zuwa 12 hours (yawa na 10)
Hanyar biyan kuɗaɗe na Medicare	$ 5 - $ 58	$ 1 - $ 3
SingleCare kudin	$ 71 +	$ 45 +

Sami katin rangwame na kantin magani

Sakamakon illa na yau da kullun na Lovenox vs. heparin

Mafi rinjayen tasirin Lovenox da heparin shine halayen gidan yanar gizo na allura. Bayan yin maganin Lovenox ko allurar heparin, zaku iya jin zafi, rashin jin daɗi, damuwa, ko kumburi a kewayen wurin allura. Koyaya, waɗannan illolin suna da sauƙi kuma suna tafiya da kansu.

Tun da Lovenox da heparin suna hana daskarewar jini, suna iya haifar da illa mai zub da jini. Yayin amfani da Lovenox ko heparin, ƙila ka sami ƙarin rauni. Hakanan Anticoagulants na iya haifar da jini mai tsanani. Alamomin zubar jini mai tsananin gaske sun hada da yawan zafin jini da jini a cikin tabon ko fitsari. Nemi likita idan kunji alamun jini mai tsanani.

Duba jadawalin da ke ƙasa don sauran sakamako masu illa na yau da kullun.

	Lovenox	Heparin
Sakamakon sakamako	Ana amfani?	Mitar lokaci	Ana amfani?	Mitar lokaci
Jin zafi, damuwa, kumburi a kusa da wurin allurar	Ee	*	Ee	*
Zuban jini	Ee	*	Ee	*
Liverananan enzymes na hanta	Ee	*	Ee	*
Ciwan	Ee	*	Ba	-
Gudawa	Ee	*	Ba	-

* ba'a ruwaito ba
Mitar ba ta dogara da bayanai daga gwajin kai-da-kai. Wannan na iya zama ba cikakken jerin illolin da zasu iya faruwa ba. Da fatan za a koma zuwa likitanku ko mai ba da sabis na kiwon lafiya don ƙarin koyo.
Source: DailyMed ( Lovenox ,, DailyMed ( Heparin )

Magungunan ƙwayoyi na Lovenox vs. heparin

Lovenox da heparin suna da ma'amala da ƙwayoyi iri ɗaya. Masu hana yaduwar platelet, ko kuma magungunan hana daukar ciki, nau'ikan magunguna ne daban wanda kuma zai iya taimakawa hana yaduwar jini. Hada maganin hana daukar ciki kamar clopidogrel, ticagrelor, ko prasugrel tare da Lovenox ko heparin na iya ƙara haɗarin zubar jini.

Magungunan anti-inflammatory marasa ƙwayar cuta (NSAIDs) na iya shafar aikin platelets . Haɗarin jini zai iya ƙaruwa lokacin shan NSAIDs tare da Lovenox ko heparin. Faɗa wa likitanka idan kana shan NSAIDs kafin fara magani akan Lovenox ko heparin.

Drug	Ajin magani	Lovenox	Heparin
Asfirin Ibuprofen Indomethacin Celecoxib	Magungunan anti-inflammatory marasa ƙwayar cuta (NSAIDs)	Ee	Ee
Clopidogrel Ticagrelor Prasugrel Dipyridamole	Wakilan Antiplatelet	Ee	Ee

Tuntuɓi ƙwararren masanin kiwon lafiya don sauran hanyoyin hulɗa da ƙwayoyi

Gargadi na Lovenox da heparin

Anticoagulants kamar Lovenox da heparin na iya ƙara haɗarin babban zub da jini, ko zubar jini. Zub da jini na iya zama mai tsanani kuma galibi ana nuna shi da alamu kamar jini a cikin fitsari ko bayan gida. Haɗarin zubar jini na iya zama mafi girma a cikin mutanen da ke da tarihin rikicewar jini.

Heparin na iya haifar cututtukan cututtukan zuciya na heparin (HIT) , Halin da ke cikin halin ƙarancin ƙarancin platelet. Duk da yake mutane ba kasafai suke samun bayyananniyar alamomin cutar ta HIT ba, yana da wata matsala ta barazanar rai wanda zai iya haifar da zub da jini sosai ko mutuwa. Idan aka kwatanta da Lovenox, heparin yana da babban haɗarin HIT. Amfani da Heparin galibi ana sanya ido sosai akan wannan dalili.

Lovenox yana ɗauke da haɗarin kashin jini na kashin baya, ko tarin jini kewaye da jijiya. Hannun daji na kashin baya zai iya haifar da rikice-rikice ko inna. Haɗarin yana ƙaruwa idan kun sami baya ko maimaita jijiyoyin baya ko huji; kuna shan NSAIDs, masu hana yaduwar platelet, da masu shan jini; ko kuna da catheter epidural.

Tuntuɓi mai ba da lafiyar ku don wasu hanyoyin kariya da suka haɗa da Lovenox da heparin.

Tambayoyi akai-akai game da Lovenox vs. heparin

Menene Lovenox?

Lovenox wani magani ne mai cike da allurar riga-kafi, ko kuma sikari na jini. Hakanan an rarraba shi azaman ƙananan ƙwayar ƙwayar heparin. Lovenox yana samuwa a cikin ƙananan 100 mg / ml da 150 mg / ml. Yawanci ana gudanar dashi sau ɗaya ko biyu a kowace rana azaman allurar subcutaneous. Sunan mahaifa na Lovenox shine enoxaparin.

Menene heparin?

Heparin ana kuma san shi da misali ko heparin da ba a raba shi ba . Akwai shi a cikin tsari ko iri-iri. Heparin ana yin shi azaman allurar cikin jini ko kuma ta karkashin jiki. Yawancin lokaci ana bayar da shi a cikin asibiti, kodayake ana iya gudanar da wasu nau'ikan maganin heparin a gida.

Shin Lovenox da heparin iri daya ne?

Lovenox da heparin ba ɗaya bane. Lovenox ƙananan heparin ne na kwayar halitta (LMWH), wanda ya sha bamban da daidaitaccen heparin (UFH). Kodayake Lovenox da heparin dukansu masu maganin hana yaduwar jini ne, suna da bambance-bambance wajen kirkira da kuma amfani da FDA.

Shin Lovenox ko heparin ne mafi kyau?

Lovenox da heparin duka suna da tasiri don magancewa da kuma hana halaye masu daskarewar jini kamar thrombosis mai zurfin ciki (DVT) da embolism embolism (PE). Lovenox yana da ƙarin hango dosing da sigogin sa ido kuma don haka, ya fi dacewa don amfani da gida. Tsawon rabin rayuwar Lovenox yana nufin za'a iya masa ɗiya sau ɗaya kowace rana.

Idan aka kwatanta da Lovenox, heparin yana buƙatar a yawaita shi akai-akai kuma a manyan allurai saboda gajeren rabin rayuwarsa. Heparin ba shi da ƙima fiye da Lovenox, kuma yawanci ana yin sa ne a cikin asibiti inda sanya idanu kan cutarwa ya fi sauƙi.

Zan iya amfani da Lovenox ko heparin yayin da nake da juna biyu?

Lovenox ko heparin suna da aminci da tasiri don magance cututtukan thromboembolic yayin daukar ciki . Duk maganin hana yaduwar jini ba ya haye mahaifa. Koyaya, ƙananan ƙwayoyin heparins (LMWHs), kamar Lovenox, sun fi dacewa don magance daskarewar jini a cikin mata masu ciki.

Zan iya amfani da Lovenox ko heparin tare da barasa?

Masu ba da kiwon lafiya sun ba da shawarar iyakancewa ko guje wa shan barasa yayin amfani da Lovenox ko heparin. Barasa na iya aiki a matsayin mai sikan jini , wanda na iya haifar da haɗarin haɗarin zub da jini lokacin da aka haɗu da giya tare da magani mai guba.

Me za'a iya amfani dashi maimakon heparin?

Ana amfani da ƙananan heparins masu nauyin nauyi (LMWHs) maimakon heparin. Lovenox (enoxaparin), Fragmin (dalteparin), da Innohep (tinzaparin) misalai ne na LMWHs waɗanda za a iya amfani dasu don magance ko hana yatsar jini. Arixtra (fondaparinux) wani wakili ne na antithrombotic, ya bambanta da LMWH da UFH, wanda zai iya hana factor Xa kuma ya bi da daskarewar jini.

Hakanan ana amfani da maganin hana yaduwar kwayoyi na kai tsaye (DOACs), wanda ya zo a cikin kwaya, a maimakon yaduwar cutar heparin. Misalan DOACs sun haɗa da Xarelto (rivaroxaban), Pradaxa (dabigatran), da Eliquis (apixaban).

Me ake amfani da Lovenox?

Ana amfani da Lovenox (enoxaparin) don maganin ƙwanƙwasa da thromboprophylaxis. Zai iya taimakawa wajen magance ko hana ƙwanƙwasa jini wanda zai iya haifar da jijiyoyin jini. Lovenox na iya taimaka wajan kula da daskarewar jini wanda ke samuwa a kafafu ko hannaye (thrombosis mai zurfin jijiya) ko kuma dasassu da suka zama cikin huhu (huhu na huhu) Lovenox kuma yana da amfani don hana rikitarwa daga angina mara ƙarfi da wasu nau'ikan cututtukan zuciya.

Shin Lovenox magani ne mai haɗari?

Lovenox babban haɗari ne, ko magani mai faɗakarwa. Kodayake gabaɗaya magani ne mai aminci, Lovenox na iya haifar da mummunan rauni da rikitarwa idan aka yi amfani dashi ba daidai ba. Idan ana ba da Lovenox a cikin mahimmancin kashi, akwai ƙarin haɗarin zubar jini da mummunan sakamako. Lovenox kawai za'a yi amfani dashi tare da takardar sayan magani da jagorar da ta dace daga mai ba da lafiya.