Celebrex vs. ibuprofen: Bambanci, kamanceceniya, kuma wanene yafi muku alheri
Magunguna vs. AbokiBayanin magunguna da manyan bambance-bambance | Yanayin da aka bi | Inganci | Inshorar inshora da kwatancen farashi | Sakamakon sakamako | Hadin magunguna | Gargadi | Tambayoyi
Arthritis an san shi da haifar da ciwo da ciwo. Akwai magunguna da yawa a can don ciwo na cututtukan zuciya wanda zai iya rikitar da wanda za'a ɗauka. Magunguna biyu na yau da kullun a cikin NSAID (nonsteroidal anti-inflammatory drug) category sune Celebrex (celecoxib) da ibuprofen.
NSAIDs na iya zama masu tasiri wajen magance osteoarthritis da rheumatoid arthritis, da kuma wasu yanayi daban-daban. Dukansu Celebrex da ibuprofen suna nan a cikin sifa iri ɗaya. Duk da yake Celebrex yana samuwa ne kawai ta hanyar takardar sayan magani, zaka iya siyan ƙananan allurai na ibuprofen a kan-kan-kanti. Mafi yawan maganin ibuprofen ana samunsu ta takardar sayan magani. Saboda Celebrex da ibuprofen suna cikin aji iri na magunguna, sun yi kama, amma kuma suna da wasu manyan bambance-bambance.
Menene manyan bambance-bambance tsakanin Lexapro vs. Zoloft?
| Babban bambance-bambance tsakanin Celebrex vs. ibuprofen | ||
|---|---|---|
| Celebrex | Ibuprofen | |
| Ajin magani | NSAID, COX-2 mai hanawa | NSAID |
| Alamar alama / ta kowa | Brand da janar | Rx: na asali OTC: alama da janar |
| Menene sunan gama-gari? Menene sunan alamar? | Saukewa: celecoxib | Alamar: Motrin, Advil (OTC) |
| Wani nau'i (s) ne miyagun ƙwayoyi ya shigo? | Capsules (50, 100, 200, 400 MG) Fom ɗin ruwa ga yara yana haɗuwa da kantin magani | Tabletsarfin ƙwayoyin magani: 400 MG, 600 MG, 800 MG OTC: 200 MG Allunan / capsules / softgels, daban-daban chewables, taya, da kuma saukad |
| Menene daidaitaccen sashi? | Manya: 200 MG kowace rana tare da abinci; matsakaicin 400 a kowace rana Madadin: 100 MG sau biyu a rana Yara daga shekaru biyu zuwa sama: ya dogara da nauyi | Manya: 200 zuwa 800 MG sau uku zuwa huɗu kowace rana tare da abinci; matsakaicin kashi ya bambanta dangane da yanayin Yara: ya bambanta dangane da shekaru, nauyi, da kuma tsarawa |
| Yaya tsawon maganin al'ada? | Ya bambanta: makonni zuwa shekaru | Ya bambanta: kwanaki zuwa makonni, wasu marasa lafiya suna ɗaukar watanni ko shekaru |
| Wanene yawanci yake amfani da magani? | Yara 'yan shekara biyu zuwa sama; manya | Yara 'yan wata shida zuwa sama; manya |
Kuna son mafi kyawun farashi akan Celebrex?
Yi rajista don faɗakarwar farashin Celebrex kuma gano lokacin da farashin ya canza!
Sami faɗakarwar farashi
Yanayin da Celebrex da Ibuprofen suka kula dashi
Celebrex, wani magani ne mai cike da kumburi wanda ba kwayar cuta (NSAID), shine aka nuna don yanayin da ke tafe: cututtukan osteoarthritis, cututtukan zuciya na yara, cututtukan yara na yara marasa lafiya shekaru biyu zuwa sama, ankylosing spondylitis, ciwo mai tsanani, dysmenorrhea na farko, da dangin adenomatous polyposis a matsayin adjunct don kulawa ta yau da kullun.
Ibuprofen shima NSAID ne kuma ana nuna shi don sauƙin alamomi da alamomin cututtukan osteoarthritis da cututtukan zuciya na rheumatoid, ciwo mai laushi zuwa matsakaici, da kuma dysmenorrhea na farko.
| Yanayi | Celebrex | Ibuprofen |
| Osteoarthritis | Ee | Ee |
| Rheumatoid amosanin gabbai | Ee | Ee |
| Ciwon yara na cututtukan zuciya (a cikin marasa lafiya shekaru biyu zuwa sama) | Ee | Ba |
| Ciwon mara | Ee | Ba |
| M zafi | Ee | Ba |
| Cutar dysmenorrhea | Ee | Ee |
| Adenomatous polyposis na iyali a matsayin ƙarin talla | Ee | Ba |
| Mai rauni zuwa matsakaici | Ba | Ee |
Magungunan NSAID suna aiki ta hanyar toshe prostaglandins (prostaglandins suna haifar da ciwo da kumburi) daga yin su. Prostaglandin ana yin shi ne ta enzymes biyu, cyclooxygenase-1 (COX-1) da kuma cyclooxygenase-2 (COX-2).
Shin Celebrex ko Ibuprofen sun fi tasiri?
An san Celebrex a matsayin mai hana COX-2 mai hanawa. Yayinda yake har yanzu NSAID kamar ibuprofen, Celebrex kawai yana toshe COX-2, sabanin ibuprofen, wanda ke toshe duka COX-1 da COX-2. Menene ma'anar wannan? Mai hana COX-2 na iya zama mai sauƙi a kan ciki, tare da ƙananan haɗarin haifar da ulcershin ciki.
A cikin nazarin asibiti don inganci, Celebrex ya nuna:
- Rage ciwon haɗin gwiwa a cikin marasa lafiya na osteoarthritis
- Rage ciwon haɗin gwiwa da kumburi a cikin marasa lafiya na cututtukan zuciya na rheumatoid
- Ingantawa ga marasa lafiya tare da cututtukan yara na yara
- Ingantawa a cikin marasa lafiya tare da cutar sankarar jiki (cikin tsananin zafi, aikin cuta, da nakasa aiki)
- Saukaka matsakaici zuwa mai tsananin ciwo wanda ya haifar da ciwon tiyata ko dysmenorrhea
A cikin karatun asibiti don inganci, ibuprofen nuna :
- Irin wannan sakamako ga asfirin a cikin marasa lafiya da cututtukan osteoarthritis da cututtukan zuciya na rheumatoid don ciwo da kumburi
- Saukaka ciwo daga episiotomy, hanyoyin haƙori, da dysmenorrhea
Wanne magani ne ya fi tasiri? Yana da wuya a ce. A daya karatu , An nuna Celebrex yana da tasiri kamar ibuprofen ga marasa lafiya da ke fama da cutar sanyin gwiwa. Wasu nazarin suna nunawa ibuprofen don zama mafi inganci, yayin da wasu ke kammalawa Celebrex na iya zama mafi tasiri.
Dangane da aminci, gwaji na asibiti na Celebrex, da kuma waɗanda ba zaɓaɓɓun NSAIDs ba (kamar ibuprofen) har zuwa shekaru uku sun nuna ƙarin haɗarin mummunan lamura na zuciya, jijiyar zuciya, da bugun jini, wanda zai iya zama m. Saboda haka, duk NSAIDs (gami da duka Celebrex da ibuprofen) na iya kasancewa haɗuwa da wannan haɗarin. Hakanan, duk NSAIDs, gami da Celebrex da ibuprofen, suna da haɗarin abubuwan GI, kamar zub da jini da marurai.
Mafi kyawun magani a gare ku kawai mai ba da sabis na kiwon lafiya ne zai iya tantance ku, wanda zai iya yin la'akari da duk hoton yanayin lafiyar ku, abubuwan haɗarin, tarihin lafiyar ku, da sauran magunguna da kuke sha.
Kuna son mafi kyawun farashi akan Ibuprofen?
Yi rajista don faɗakarwar farashin Ibuprofen kuma gano lokacin da farashin ya canza!
Sami faɗakarwar farashi
Verageaukar hoto da kwatancen farashi na Celebrex vs. Ibuprofen
Celebrex galibi inshora ne da Medicare Sashe na D ke rufe shi ta hanyar tsarinta na celecoxib. Takaddun magani na yau da kullun zai kasance don capsules 30 na 200 mg celecoxib. Farashin kuɗi daga cikin aljihu kusan $ 217.49 amma zaka iya samun celecoxib na $ 105-145 a shagunan sayar da magani tare da sigar SingleCare.
Ibuprofen yawanci ana rufe shi ta inshora da Medicare Sashe na D, a cikin ƙarfin sayan magani na 400 MG, 600 MG, da 800 MG. Dokokin likita sun bambanta. Misali, farashin sayarwa na allunan 30 na 800 mg ibuprofen farashinsu ko'ina daga $ 6-30. Tare da takaddun SingleCare, farashin ibuprofen shine $ 4-8.
| Celebrex | Ibuprofen | |
| Yawanci inshora ya rufe? | Ee; janar | Ee; presarfin magani |
| Yawanci an rufe shi ta Medicare Part D? | Ee; janar | Ee; presarfin magani |
| Daidaitaccen sashi | 30, 200 mg capsules na jinsin celecoxib | 30, 800 MG Allunan na ibuprofen |
| Hankula Medicare Part D copay | $ 0-150 | $ 0-14 |
| SingleCare kudin | $ 105-145 | $ 4-8 |
Sakamakon sakamako na Celebrex vs. Ibuprofen
Abubuwan da suka fi faruwa na Celebrex da ibuprofen sun hada da ciwon ciki, gudawa, rashin narkewar abinci, da ciwon kai. Duba ɓangaren faɗakarwa don ƙarin bayani game da haɗarin zuciya da haɗarin zubar jini na GI.
| Celebrex | Ibuprofen | |||
| Tasirin Side | Ana amfani? | Mitar lokaci | Ana amfani? | Yanayi * |
| Ciwon ciki | Ee | 4.1% | Ee | 3-9% |
| Gudawa | Ee | 5.6% | Ee | 3-9% |
| Dyspepsia (rashin narkewar abinci) | Ee | 8.8% | Ee | 3-9% |
| Ciwon kai | Ee | 15.8% | Ee | 3-9% |
* Ba a bayar da yawan tasirin illa na ibuprofen da bayanan magani ba; kawai cewa waɗannan tasirin sun faru a cikin 3-9% na marasa lafiya.
Source: DailyMed (Celebrex) , DailyMed ( ibuprofen )
Wannan ba cikakken lissafi bane; wasu illoli na iya faruwa. Yi shawara tare da mai ba ka kiwon lafiya don cikakkun bayanai.
Magungunan ƙwayoyi na Celebrex da Ibuprofen
Celebrex da ibuprofen suna da yawancin ma'amala iri ɗaya tare da wasu magungunan ƙwayoyi. Dukansu magunguna suna hulɗa tare da masu rage jini kamar Coumadin (warfarin), wasu magungunan hawan jini (masu hana ACE, ARBs, da masu hana beta), magungunan kashe ciki, da masu yin diuretics kamar hydrochlorothiazide da methotrexate. Tuntuɓi mai ba da kiwon lafiya don jagora.
Ya kamata a guji giya yayin shan Celebrex ko ibuprofen. Amfani da ɗayan waɗannan magunguna tare da barasa na iya ƙara haɗarin jinin GI (ciki) ko kumburi. Haɗin zai iya haifar da lalacewar koda ko gazawar koda.
Wannan jerin jerin abubuwan hulɗar miyagun ƙwayoyi ne. Tuntuɓi mai ba da lafiya don ƙarin bayani.
| Drug | Ajin Magunguna | Celebrex | Ibuprofen |
| Coumadin (warfarin) | Anticoagulant | Ee | Ee |
| Zestril (lisinopril), Cozaar (losartan), da sauransu | ACE masu hanawa, ARBs | Ee | Ee |
| Tenormin (atenolol), Toprol XL ko Lopressor (metoprolol) | Masu hana Beta | Ee | Ee |
| Diflucan (fluconazole) | Antifungal | Ee | Ba |
| Lasix (furosemide), hydrochlorothiazide | Diuretics | Ee | Ee |
| Naproxen, Mobic (meloxicam) | Sauran NSAIDs | Ee | Ee |
| Samun bayanai | Antimetabolite | Ee | Ee |
| Zoloft (sertraline), Paxil (paroxetine), Prozac (fluoxetine), Effexor (venlafaxine), Desyrel (trazodone), Elavil (amitriptyline), da sauransu | Magungunan Magunguna | Ee | Ee |
| Barasa | Barasa | Ee | Ee |
Gargadi na Celebrex da Ibuprofen
Ya kamata a guji Celebrex a cikin marasa lafiyar da ke rashin lafiyan NSAIDs, da kuma marasa lafiyar da ke rashin lafiyan sulfa. Ya kamata a guji Ibuprofen a cikin marasa lafiyar da ke rashin lafiyan NSAIDs.
Saboda duka kwayoyi NSAIDs ne, Celebrex da ibuprofen suna da gargaɗi iri ɗaya. Suna da gargaɗin dambe (gargaɗi mafi ƙarfi kamar yadda Hukumar Abinci da Magunguna, ko FDA) ke buƙata. Celebrex ko ibuprofen na iya ƙara haɗarin mummunan lamura na zuciya da jijiyoyin jini, MI (ciwan zuciya, ko bugun zuciya), da bugun jini, dukkansu na iya zama m. Duk NSAIDs suna da irin wannan haɗarin, wanda ya ƙara tsawon lokacin da kuke amfani da shi. Marasa lafiya tare da cututtukan zuciya ko waɗanda ke da halayen haɗarin zuciya da haɗari suna cikin haɗari mafi girma. Kada a yi amfani da Celebrex ko ibuprofen don jin zafi yayin aikin tiyatar jijiya na jijiya (CABG).
Hakanan a cikin gargaɗin dambe akwai haɗarin mummunan GI, ko abubuwan da ke faruwa a cikin ciki, gami da zub da jini, maƙarƙashiya, da ɓarkewar ciki ko hanji, wanda zai iya zama na mutuwa. Duk waɗannan abubuwan na iya faruwa a kowane lokaci, kuma ba tare da alamun gargaɗi ba. Marasa lafiya tsofaffi da waɗanda ke da tarihin marurai ko jinin GI suna cikin haɗari mafi girma ga abubuwan GI masu tsanani.
Sauran gargaɗin Celebrex da ibuprofen sun haɗa da:
- Hadarin haɓakar hanta mai haɗarin enzymes kuma, da wuya, halayen halayen hanta mai tsanani.
- Sabbin lokuta ko kara hauhawar jini (hawan jini). Yi amfani da hankali a cikin marasa lafiya na hauhawar jini; kula da hawan jini sosai yayin jiyya.
- Rike ruwa da kuma edema. Yi amfani da hankali a cikin marasa lafiya tare da riƙewar ruwa ko gazawar zuciya
- Renal papillary necrosis / sauran rauni na koda tare da amfani mai tsawo. Yi amfani da hankali a cikin tsofaffi, marasa lafiya tare da larurar koda, rashin aiki na zuciya, matsalar hanta, da marasa lafiya waɗanda ke shan diuretics, masu hana ACE, ko masu hana angiotensin II.
- Hanyoyin Anaphylactoid. Kada kayi amfani dashi don marasa lafiya tare da Sample's triad .
- M halayen na iya faruwa kamar exfoliative dermatitis, Stevens-Johnson ciwo (SJS), da kuma mai guba epidermal necrolysis (TEN), wanda zai iya zama m da faruwa ba tare da gargadi. Dakatar da Celebrex kuma nemi magani na gaggawa idan kurji ko tasirin fata ya auku.
Akwai iyakantattun bayanai akan NSAIDs da ake amfani dasu a ciki. Amfani da dukkan NSAIDs, gami da Celebrex da ibuprofen duka, a lokacin watanni uku na ciki, yana ƙara haɗarin wanda bai yi daidai ba rufewa da tayi . Sabili da haka, kada a yi amfani da NSAIDs bayan makonni 30 na ciki.
Tuntuɓi mai ba da lafiyar ku game da amfani da Celebrex ko ibuprofen a cikin ciki. Idan kana shan riga Celebrex ko ibuprofen kuma ka gano cewa kana da juna biyu, tuntuɓi mai ba ka kiwon lafiya don jagora.
Akwai iyakance bayanai kan Celebrex da ibuprofen tare da shayarwa; nemi likita don jagora.
Tambayoyi akai-akai game da Celebrex vs. Ibuprofen
Menene Celebrex?
Celebrex magani ne mai cutar anti-inflammatory (NSAID) wanda aka nuna don yanayin masu zuwa: osteoarthritis, arthritis na rheumatoid, cututtukan yara na yara a cikin marasa lafiya shekaru biyu zuwa sama, ankylosing spondylitis, ciwo mai tsanani, dysmenorrhea na farko, da adenomatous polyposis na dangi a matsayin adjunct zuwa saba kulawa.
Menene Ibuprofen?
Ibuprofen shine NSAID kuma ana amfani dashi don magance alamomi da alamun cututtukan osteoarthritis, cututtukan zuciya na rheumatoid, ciwo mai sauƙi zuwa matsakaici, da dysmenorrhea na farko.
Shin Celebrex da Ibuprofen iri daya ne?
Saboda duka kwayoyi NSAIDs ne, suna kama da juna kuma suna da sakamako iri iri da gargaɗi. Sun bambanta a alamomi da farashi. Duba sama don neman ƙarin bayani game da kamanceceniya da banbancin ra'ayi.
Shin Celebrex ko Ibuprofen sun fi kyau?
Duk kwayoyi biyu na iya zama masu tasiri sosai wajen magance cututtukan zuciya da sauran yanayi. Dogaro da irin yanayin da kake bi, da kuma la'akari da duk wasu sharuɗɗan kiwon lafiya da abubuwan haɗarin da kake dasu, da kuma wasu magunguna da kake sha, likitanka na iya taimaka maka shawarar maganin da ya dace maka.
Zan iya amfani da Celebrex ko Ibuprofen yayin da nake da juna biyu?
Idan kun gano kuna da ciki kuma kuna amfani da Celebrex ko ibuprofen tuntuɓi mai ba ku kiwon lafiya don shawarwari.
Mata masu ciki ba za suyi amfani da waɗannan NSAIDs ba bayan makonni 30 na ciki. Yin amfani da Celebrex da ibuprofen a yayin watanni uku na ciki na iya kara barazanar rufewar tayin arteriosus da wuri.
Zan iya amfani da Celebrex ko Ibuprofen tare da barasa?
Ba . Amfani da ɗayan waɗannan magunguna tare da barasa na iya ƙara haɗarin jinin GI (ciki) ko kumburin ciki. Haɗin zai iya haifar da lalacewar koda ko gazawar koda.
Shin Celebrex ya fi ibuprofen tasiri?
Duk kwayoyi biyu na iya zama masu tasiri sosai wajen magance cututtukan arthritis da sauran yanayi. Yi shawara tare da mai ba da lafiyar ku don sanin wane magani ne mafi kyau a gare ku idan aka ba da yanayin ku, tarihin lafiyar ku, da sauran magunguna da za ku iya sha.
Me yasa suka cire Celebrex daga kasuwa?
Celebrex har yanzu yana kan kasuwa kamar na yau. Vioxx (rofecoxib), irin wannan magani ne ga Celebrex, ya kasance cire daga kasuwa ta hannun masana'anta, Merck, a 2004, saboda karuwar haɗarin al'amuran zuciya da jijiyoyin jiki tare da amfani mai ɗorewa. A cikin 2005, wani magani mai kama, Bextra (valdecoxib), ya kasance ja daga kasuwa ta masana'anta Pfizer don dalilai guda ɗaya.
Shin Celebrex mai kashe zafi ne?
Celebrex magani ne na NSAID (nonsteroidal anti-inflammatory) wanda ke taimakawa tare da alamun ciwo da kumburi daga yanayi daban-daban (duba sama). Saboda kawai yana aiki akan enzymes na COX-2, yana iya zama mafi aminci ga ciki, kodayake har yanzu akwai haɗarin GI.
