Symbicort vs. Advair: Bambanci, kamanceceniya, kuma wanene yafi muku alheri
Magunguna vs. AbokiBayanin magunguna & manyan bambance-bambance | Yanayin da aka bi | Inganci | Inshorar inshora da kwatancen farashi | Sakamakon sakamako | Hadin magunguna | Gargadi | Tambayoyi
Symbicort da Advair magunguna ne masu dauke da suna guda biyu wadanda ake amfani da su wajen magance cutar asma da kuma cututtukan huhu na huhu (COPD). Asthma da COPD yanayi ne da ke shafar huhu kuma yana haifar da kumburi a hanyoyin iska. Kwayar cututtukan asma da COPD sun hada da matsalar numfashi, shaka iska, da tari.
Symbicort da Advair sune masu shaƙatawa wanda ke haɗa corticosteroid da aka shaƙa (ICS) tare da mai aiki mai saurin beta (LABA). Ana amfani da waɗannan inhalers a kullun don taimakawa sarrafa kumburi a cikin huhu da kuma buɗe hanyoyin iska a buɗe. Ba a amfani da su azaman inhalers na ceto don tsananin alamun asma ko COPD. Duk da kamanceceniyarsu, Symbicort da Advair suna da wasu bambance-bambance a cikin mayuka masu aiki da sashi mai faɗi.
Menene manyan bambance-bambance tsakanin Symbicort da Advair?
Symbicort da Advair suna ƙunshe da corticosteroid, wanda ke da tasirin maganin kumburi a cikin huhu. Symbicort ya ƙunshi corticosteroid budesonide yayin da Advair ya ƙunshi corticosteroid fluticasone. Symbicort da Advair suma suna dauke da mai aiki da dogon lokaci, wanda ke taimakawa bude hanyoyin iska; Symbicort yana dauke da formoterol yayin da Advair ke dauke da salmeterol.
Symbicort ana amfani dashi azaman magani na kulawa ga COPD, kuma ana iya amfani dashi don magance asma a cikin mutane masu shekaru 6 zuwa sama. Advair ana amfani dashi azaman maganin kulawa da COPD, kuma ana iya amfani dashi don magance asma a cikin mutane masu shekaru 4 zuwa sama. Maganin Symbicort shine yawan shaka sau biyu a rana sau biyu yayin da Advair yake shan iska sau biyu a rana.
Symbicort yana zuwa kamar inhalation aerosol tare da ƙarfin ko dai 80 / 4.5 mcg ko 160 / 4.5 mcg na budesonide / formoterol. Advair yana samuwa azaman inhalation aerosol da inhalation foda, amma inhalation aerosol an yarda dashi ne kawai don magance asma yayin da inhalation foda zai iya magance duka asma da COPD. Advair HFA shine inhaler mai auna awo wanda yake bada inhalation aerosol a karfin 45/21 mcg, 115/21 mcg, ko 230/21 mcg na fluticasone / salmeterol. Advair Diskus yana ba da foda mai shaƙa tare da ƙarfin 100/50 mcg, 250/50 mcg, ko 500/50 mcg na fluticasone / salmeterol.
| Babban banbanci tsakanin Symbicort da Advair | ||
|---|---|---|
| Symbicort | Yi aiki | |
| Ajin magani | ICS (inhaɗa corticosteroid) da LABA (mai saurin aiki beta2-adrenergic agonist) | ICS (inhaɗa corticosteroid) da LABA (mai saurin aiki beta2-adrenergic agonist) |
| Alamar alama / ta kowa | Nau'in samfura da na yau da kullun akwai | Nau'in samfura da na yau da kullun akwai |
| Menene sunan jimla? | Budesonide da formoterol fumarate dihydrate | Fluticasone propionate da salmeterol |
| Wani nau'i (s) ne miyagun ƙwayoyi ya shigo? | Inhalation aerosol (inhaler metered-kashi) | Inhalation aerosol (inhaler metered-kashi) Inhalation foda (diskus) |
| Menene daidaitaccen sashi? | Jiyya na asma a cikin marasa lafiya shekaru 12 zuwa sama: 2 shakar Symbicort 80 / 4.5 ko 160 / 4.5 sau biyu a rana Jiyya na asma a cikin marasa lafiya shekaru 6 zuwa ƙasa da shekaru 12: 2 shakar Symbicort 80 / 4.5 sau biyu a rana Kulawa da COPD: 2 shakar Symbicort 160 / 4.5 sau biyu a rana | Advair Diskus Jiyya na asma a cikin marasa lafiya shekaru 12 zuwa sama: Shakar 1 na Advair Diskus 100/50, 250/50, ko 500/50 sau biyu a rana Jiyya na asma a cikin marasa lafiya shekaru 4 zuwa 11 shekaru: 1 shakar Advair Diskus 100/50 sau biyu a rana Kulawa da COPD: Shakar 1 na Advair Diskus 250/50 sau biyu a rana Advair HFA |
| Yaya tsawon maganin al'ada? | Dogon lokaci | Dogon lokaci |
| Wanene yawanci yake amfani da magani? | Manya da yara 'yan shekara 6 zuwa sama | Manya da yara shekaru 4 zuwa sama |
Yanayi na Symbicort da Advair
Symbicort da Advair duka an yarda da FDA don magance asma da COPD. Koyaya, Advair Diskus an yarda dashi don magance asma da COPD yayin da Advair HFA kawai aka yarda dashi don magance asma. Symbicort da Advair ana amfani dasu azaman masu shan magani wanda ake amfani dasu yau da kullun don sarrafawa da kuma hana COPD da alamun asma, kamar ƙarancin numfashi da kuzari.
Lokacin amfani dasu na dogon lokaci, waɗannan magungunan na iya taimakawa rage ƙima da yawan COPD kuma ciwon asma , ko kara damuwa. Don kulawa da saurin bayyanar cututtukan COPD ko asma, mai ba da sabis na kiwon lafiya zai ba da izinin inhaler mai ceto kamar albuterol, wanda kuma aka san shi da sunaye kamar Ventolin da ProAir.
| Yanayi | Symbicort | Yi aiki |
| Asthma | Ee | Ee |
| COPD | Ee | Ee |
Shin Symbicort ko Advair sun fi tasiri?
Dukkan Symbicort da Advair suna shaƙar iska idan aka ɗauke su akai-akai. Dukansu suna ƙunshe da irin waɗannan abubuwa masu aiki waɗanda ke taimakawa rage ƙonewa a cikin huhu da buɗe hanyoyin iska. Yi magana da mai ba da kiwon lafiya don nemo mafi ƙarancin inhaler da ke aiki a gare ku.
A cewar wani meta-bincike , inhaler tare da duka inhakar corticosteroid da mai aiki da dogon lokaci sunada inganci don rage cututtukan COPD fiye da inhaler mai ɗauke da mai aiki da dadewa. Babu gwajin kai-da-kai wanda ya kwatanta abubuwan da ke aiki cikin Symbicort da Advair kai tsaye da aka sake dubawa a cikin binciken. Koyaya, binciken ya gano cewa, gabaɗaya, inhalers na haɗuwa masu tasiri iri ɗaya suma suna da tasiri.
Randomaya daga cikin bazuwar, gwaji na asibiti mai makafi biyu ya gano cewa sinadaran aiki a Symbicort da Advair suna samarwa irin wannan inganta a cikin aikin huhu, kwanakin kula da asma, da ingancin rayuwa mai nasaba da asma. Duk magungunan biyu sun rage haɗarin shiga asibiti ko ziyarar gaggawa a cikin gida sakamakon lalacewar alamun asma. An gudanar da binciken ne a tsakanin mutane 2,866 da ke da shekaru 16 zuwa sama.
Verageaukar hoto da kwatancen farashi na Symbicort vs. Advair
Symbicort galibi yana rufe mafi yawan Medicare da tsare-tsaren inshora. Hakanan ana samun shi azaman magani na yau da kullun, wanda zai iya zama mai arha fiye da nau'in sunan-iri. Matsakaicin farashin farashin Symbicort yana kusan $ 550. Kuna iya sayan Symbicort na kimanin $ 250 tare da shirin ajiya ko katin ragi, kamar katin SingleCare.
Advair kuma yawanci ana rufe shi ta Medicare da tsare-tsaren inshora. Kamar Symbicort, Advair yana zuwa ta wani nau'in tsari. Idan aka kwatanta da Symbicort, matsakaiciyar farashin Advair HFA na iya zama mafi girma a kusan $ 584. Matsakaicin farashin Advair Diskus yana kusan $ 494. Kuna iya ajiyewa akan farashin Advair HFA ko Advair Diskus tare da katin coupon na SingleCare a shagunan sayar da magani.
| Symbicort | Yi aiki | |
| Yawanci inshora ke rufe shi? | Ee | Ee |
| Yawanci an rufe shi ta Medicare Part D? | Ee | Ee |
| Yawan | 1 shakar iska | 1 shakar iska |
| Hanyar biyan kuɗaɗe na Medicare | $ 19- $ 399 | $ 2 - $ 425 |
| SingleCare kudin | $ 248 + | $ 288 + |
Illolin gama gari na Symbicort vs. Advair
Dukkan Symbicort da Advair suna da irin wannan tasirin na illa. Dukkanin magungunan biyu na iya haifar da illa kamar ciwon kai, nasopharyngitis, cututtukan da suka shafi numfashi na sama, mashako, da toshewar hanci. Sauran illolin na iya hada da jiri, amai, kumburin fuska, da ciwon baya.
Sashin steroid na Symbicort da Advair na iya ƙara haɗarin kamuwa da cutar baki, ko cututtukan fungal a cikin baki. A dalilin wannan, yana da mahimmanci a kurkure baki da ruwa bayan kowane amfani da sinadarin shakar iska. Hakanan za'a iya haɗa wata na'urar da ake kira spacer ga masu shaƙar allurai don a rage haɗarin kamuwa da cutar ta baki.
Abubuwan da ke iya haifar da mummunan sakamako na magungunan ICS / LABA sun haɗa da gurɓataccen bronchospasm da anaphylaxis. Ba a fahimci dalilin sanadin gurguntaccen iska ba. Koyaya, yana iya faruwa azaman faratowar numfashi, ƙarancin numfashi, da tari bayan amfani da magani mai shaƙar iska. Anaphylaxis na iya faruwa saboda rashin lafiyan kowane irin abu a Symbicort ko Advair. Nemi agajin gaggawa idan kun sami mummunan kurji, kumburi, ko matsalar numfashi bayan amfani da inhaler mai haɗuwa.
| Symbicort | Yi aiki | |||
| Sakamakon sakamako | Ana amfani? | Mitar lokaci | Ana amfani? | Mitar lokaci |
| Ciwon kai | Ee | 7% | Ee | 12% |
| Nasopharyngitis | Ee | goma sha ɗaya% | Ee | * |
| Babban kamuwa da cuta na numfashi | Ee | 8% | Ee | 27% |
| Bronchitis | Ee | 5% | Ee | kashi biyu |
| Cutar hanci | Ee | 3% | Ee | * |
| Maganin baka | Ee | 1% | Ee | 1% |
| Ciwan | Ee | * | Ee | 4% |
| Amai | Ee | 1% | Ee | 4% |
| Rashin tsufa | Ee | * | Ee | 5% |
| Ciwon baya | Ee | 3% | Ee | * |
* ba'a ruwaito ba
Mitar ba ta dogara da bayanai daga gwajin kai-da-kai. Wannan na iya zama ba cikakken jerin tasirin illa bane wanda zai iya faruwa. Da fatan za a koma zuwa likitanku ko mai ba da sabis na kiwon lafiya don ƙarin koyo.
Source: DailyMed ( Symbicort ,, DailyMed ( Yi aiki )
Magungunan ƙwayoyi na Symbicort vs. Advair
Ana ba da hankali yayin amfani da Symbicort ko Advair tare da magunguna waɗanda sune masu hana CYP3A4, kamar ritonavir, ketoconazole, da clarithromycin. Samun mai hana CYP3A4 tare da Symbicort ko Advair na iya haifar da ƙarin matakan jini na ɓangaren corticosteroid, wanda zai haifar da mummunan sakamako.
Yin amfani da magungunan hana kumburi na monoamine (MAOIs) ko tricyclic antidepressants tare da Symbicort ko Advair na iya ƙara tasirin jijiyoyin zuciya na ɓangaren beta-agonist a cikin ko dai magani. A gefe guda, masu hana beta na iya rage tasirin beta-agonist a cikin huhu. Diuretics na iya haifar da canjin lantarki ko ƙananan matakan potassium (hypokalemia) lokacin amfani da Symbicort ko Advair.
| Drug | Ajin magani | Symbicort | Yi aiki |
| Ritonavir Atazanavir Ketoconazole Clarithromycin Indinavir Itraconazole Nefazodone Nelfinavir Saquinavir | Masu hana CYP3A4 | Ee | Ee |
| Selegiline Rasagiline Phenelzine Isocarboxazid | Monoamine oxidase masu hanawa (MAOIs) | Ee | Ee |
| Amitriptyline Nortriptyline | Magungunan antioxidric na Tricyclic | Ee | Ee |
| Metoprolol Atenolol Bisoprolol Nebivolol Propranolol | Masu hana Beta | Ee | Ee |
| Furosemide Bumetanide Torsemide Chlorthalidone | Diuretics | Ee | Ee |
Tuntuɓi ƙwararren masanin kiwon lafiya don sauran hanyoyin hulɗa da ƙwayoyi.
Gargadi na Symbicort da Advair
Saboda suna dauke da corticosteroid, Symbicort da Advair na iya haifar da barazanar kamuwa da cuta ko raguwar ma'adinai da kashi. Koyaya, idan aka kwatanta da corticosteroids na tsarin, corticosteroids mai shaƙa yana da ƙananan haɗarin waɗannan tasirin. Hakanan maye gurbin adrenal na iya faruwa yayin amfani da babban maganin Symbicort ko Advair.
Amfani da Symbicort ko Advair na dogon lokaci na iya ƙara haɗarin glaucoma ko ciwon ido. Dole ne masanin ido ya buƙaci tuntuɓi idan alamun cututtukan ido sun haɓaka cikin lokaci tare da amfani da ɗayan waɗannan magunguna.
Ya kamata a kula da amfani da Symbicort ko Advair a cikin marasa lafiya masu fama da cututtukan zuciya, cututtukan tsarin tsakiya, rikicewar rikicewar cuta, da ciwon sukari. Yi magana da mai ba da kiwon lafiya don ƙarin faɗakarwa da kiyayewa kafin amfani da Symbicort ko Advair.
Tambayoyi akai-akai game da Symbicort vs. Advair
Menene Symbicort?
Symbicort magani ne mai suna wanda AstraZeneca ya kirkira. Ya ƙunshi budesonide da formoterol, waɗanda ke taimakawa wajen hanawa da sarrafa alamun asma da COPD. Symbicort an yarda da shi don magance cutar asma a cikin marasa lafiya shekaru 6 zuwa sama. Ana samuwa azaman inhalation aerosol wanda ake amfani dashi sau biyu a rana.
Menene Advair?
Advair magani ne mai suna na GlaxoSmithKline. Ya ƙunshi fluticasone da salmeterol. Advair shine FDA ta amince dashi don hanawa da sarrafa alamun COPD da asma. An yarda ya bi da asma a cikin marasa lafiya shekaru 4 zuwa sama. Ana samun Advair a matsayin foda mai shaƙa (Advair Diskus), wanda zai iya magance asma da COPD, da kuma inhalation aerosol (Advair HFA), wanda aka yarda da shi don magance asma. Ana amfani da dukkanin hanyoyin sau biyu a rana.
Shin Symbicort da Advair iri daya ne?
Symbicort da Advair ana amfani dasu don magance asma da COPD. Koyaya, suna ƙunshe da abubuwa daban-daban masu aiki. Symbicort ya ƙunshi budesonide da formoterol yayin da Advair ya ƙunshi fluticasone da salmeterol. Symbicort zai iya magance asma a cikin marasa lafiya shekaru 6 zuwa sama yayin da Advair zai iya kula da asma ga marasa lafiya shekaru 4 zuwa sama. Hakanan ana samun Advair azaman inhalation foda ko aerosol yayin da Symbicort kawai ake samu azaman inhalation aerosol.
Shin Symbicort ko Advair ne mafi kyau?
Duk Symbicort da Advair suna da tasiri don magance COPD da alamun asma. Saboda sune magungunan kulawa, yakamata ayi amfani dasu kullun don iyakar tasiri. Ya kamata a tabbatar da mafi ingancin inhaler mai kulawa ta hanyar yin la’akari da dalilai kamar su tasirin illa, sashi, da tsada.
Shin zan iya amfani da Symbicort ko Advair yayin da nake da juna biyu?
Babu wadataccen bincike da zai nuna cewa Symbicort ko Advair na da lafiya ko cutarwa yayin daukar ciki. A cewar Asimar Asma da Allergy Foundation of America (AAFA), masu fama da cutar beta tsawon lokaci sune ba da shawarar azaman maganin farko na asma a cikin masu juna biyu. Madadin haka, ana iya ba da shawarar yin gajeren aiki na bronchodilator. Tuntuɓi mai ba da sabis na kiwon lafiya don shawarar likita kan COPD da zaɓuɓɓukan maganin asma yayin da suke ciki.
Zan iya amfani da Symbicort ko Advair tare da barasa?
Ba a san giya da ma'amala da Symbicort ko Advair ba. Amfani da giya na yau da kullun na iya tsoma baki tare da ikon garkuwar jiki don yaƙar cututtuka, wanda zai iya haɓaka sakamakon mummunan asma ko COPD. Yi magana da mai ba da kiwon lafiya game da ko lafiya shan shan barasa yayin amfani da Symbicort ko Advair.
Abin da inhaler yake daidai da Symbicort?
Akwai nau'ikan sigar Symbicort. Tsarin jigilar abubuwa, wanda ya ƙunshi budesonide da formoterol, yayi daidai da Symbicort. Hakanan nau'in jigilar na iya zama mai sauƙi mai rahusa zuwa inhaler sunan mai amfani. Makamantan masu shaƙar cutar zuwa Symbicort sun haɗa da Advair (fluticasone / salmeterol), Dulera (mometasone / formoterol), da Breo (fluticasone / vilanterol). Waɗannan inhalers na iya aiki iri ɗaya da Symbicort, amma ba a ɗaukarsu daidai da Symbicort.
Menene mafi ingancin inhaler na COPD?
Inhalers na haɗin ICS / LABA ana ɗaukar su masu inganci da aminci don magance COPD. Koyaya, corticosteroids da aka shaƙa suna ɗauke da haɗarin ciwon huhu a cikin mutanen da ke da COPD mai ci gaba. Inhalers masu haɗuwa da LAMA / LABA ana ɗaukar su masu inganci kuma mafi aminci fiye da inhalers na haɗin ICS / LABA saboda wannan dalili. Inhalers masu haɗuwa da LAMA / LABA sun haɗa da Anoro (umeclidinium / vilanterol), Stiolto (tiotropium / olodaterol), da Bevespi (glycopyrrolate / formoterol).
