Shingrix vs. Zostavax: Bambanci, kamance, kuma wanne ne mafi alheri a gare ku
Magunguna vs. AbokiBayanin magunguna & manyan bambance-bambance | Yanayin da aka bi | Inganci | Inshorar inshora da kwatancen farashi | Sakamakon sakamako | Hadin magunguna | Gargadi | Tambayoyi
A halin yanzu akwai alluran rigakafi guda biyu waɗanda za a iya ba su don hana kamuwa da cututtukan herpes, wanda aka fi sani da shingles: Shingrix da Zostavax. Ana ba da shawarar rigakafin shingles ga manya da zarar sun cika shekaru 50.
Mafi yawan mutane sun kamu da kwayar cutar varicella zoster idan sun taba kamuwa da cutar kaza. Bayan cutar kaji ta warware, kwayar cutar varicella zoster tana kwance a jiki tsawon shekaru, in ba har abada ba. Daga baya a rayuwa, kwayar cutar na iya sake kunnawa azaman shingles kuma ya haifar da raɗaɗi mai raɗaɗi wanda yawanci yakan zagaye fuska ko jiki.
Kodayake Shingrix da Zostavax suna aiki ta hanyoyi iri ɗaya don hana shingles, akwai wasu mahimman bambance-bambance tsakanin su.
Menene manyan bambance-bambance tsakanin Shingrix da Zostavax?
Shingrix (Menene Shingrix?) Shine recombinant, adjuvanted zoster rigakafi wanda aka fara amincewa da FDA a cikin 2017. Yana amfani da varicella-zoster glycoprotein E antigen don samar da amsa mai kariya a jiki. Wani adjuvant, ko kuma wanda aka kara, na taimakawa wajen inganta garkuwar jiki ga kwayar. Saboda Shingrix allura ce ta rashin aiki, ana iya amfani da ita a cikin marasa lafiyar da ke rigakafin rigakafi ko waɗanda ke da rauni a garkuwar jiki.
Ana yin Shingrix a matsayin allura a cikin jijiya (intramuscular). Ana bayar da shi a cikin allurai daban daban biyu tare da lokaci na watanni biyu zuwa shida tsakani. Kashi na biyu ya zama dole don tabbatar da ingancin aiki na dogon lokaci.
Zostavax, wanda aka yarda dashi a cikin 2006, shine maganin rigakafin cututtukan cututtukan cututtukan ƙwayoyin cuta. A wasu kalmomin, Zostavax ya ƙunshi fasalin da aka raunana na ainihin ƙwayoyin cuta don samar da martani na rigakafi. Saboda wannan, ba a ba da shawarar ga waɗanda ke da rigakafin rigakafi ba. Ko kuma, maganin kansa zai iya haifar da kamuwa da cuta.
Ana gudanar da Zostavax azaman allura guda ɗaya a ƙasan fata (subcutaneous). Ya zo a cikin wani daskararre version da kuma Sigar yanayin firji . Dole ne a adana daskararren daskararren yayin safara da adana shi don tabbatar da ingancin sa yayin da mai daskarewa da Zostavax za a iya ajiye shi cikin firiji har sai an yi amfani da shi.
| Babban banbanci tsakanin Shingrix da Zostavax | ||
|---|---|---|
| Shingrix | Zostavax | |
| Ajin magani | Alurar rigakafi | Alurar rigakafi |
| Alamar alama / ta kowa | Suna na kawai | Suna na kawai |
| Menene sunan jimla? | Zoster Allura Recombinant, Adjuvanted | Rigakafin Zoster Kai Tsaye |
| Wani nau'i (s) ne miyagun ƙwayoyi ya shigo? | Dakatarwa don allurar intramuscular | Dakatarwa don allurar subcutaneous |
| Menene daidaitaccen sashi? | Gudanar da kashi 1 (0.5 ml) sannan wani kashi (0.5 ml) tsakanin watanni 2 da 6 daga baya | Gudanar da kashi ɗaya (0.65 ml) sau ɗaya |
| Yaya tsawon maganin al'ada? | Alurar riga kafi an gama a cikin watanni 2 zuwa 6 bayan allurai 2 | Alurar riga kafi an gama bayan an yi ta kashi 1 |
| Wanene yawanci yake amfani da magani? | Manya shekara 50 zuwa sama | Manya shekara 50 zuwa sama |
Yanayin da Shingrix da Zostavax suka kula da shi
Shingrix da Zostavax an yarda da FDA don hana shingles (herpes zoster). Dukkanin rigakafin ana nuna su don hana shingles a cikin manya masu shekaru 50 zuwa sama. Ba a amfani da Shingrix da Zostavax don hana kamuwa da cuta mai saurin cutar varicella, wanda aka fi sani da chickenpox.
Neuralgia Postherpetic wani nau'in ciwo ne na yau da kullun wanda ya taso tare da shingles. Saboda Shingrix da Zostavax na iya hana shingles, za su iya kuma hana ƙananan ƙwaƙwalwa (PHN) da sauran rikitarwa masu zafi daga shingles. Koyaya, waɗannan alurar rigakafin ba'a lakafta su don magance PHN ba.
| Yanayi | Shingrix | Zostavax |
| Rigakafin cututtukan ƙwayoyin cuta (shingles) | Ee | Ee |
Shin Shingrix ko Zostavax sun fi tasiri?
Shingrix da Zostavax duka an tabbatar da su don hana shingles. Koyaya, Shingrix sabuwar rigakafi ce wacce ake ɗaukarta fiye da Zostavax. Har ila yau ana ba da shawarar Shingrix ga waɗanda suka riga sun karɓi allurar ta Zostavax a baya.
Gwajin gwaji ya nuna cewa Shingrix shine 97% tasiri a hana shingles a cikin manya masu shekaru 50 zuwa 69 shekaru. Shingrix shima yana da tasiri wajen hana shingles a cikin manya - manya sama da shekaru 70, Shingrix shine 91% tasiri .
Zostavax yana da 70% inganci rateididdigar hana shingles a cikin tsofaffi masu shekaru 50 zuwa 69 shekaru, bisa ga Zoster Efficacy and Safety Trial (ZEST). Sakamako daga Nazarin Rigakafin Shingles ya nuna cewa Zostavax yana da tasiri 51% akan shingles. Idan aka kwatanta da Shingrix, tasirin Zostavax yana raguwa a cikin rukunin tsofaffi. Dangane da sakamakon SPS, Zostavax yana da tasiri na 64% a cikin manya masu shekaru 60 zuwa 69 shekaru; 41% yana da tasiri a cikin manya masu shekaru 70 zuwa 79; kuma 18% yana da tasiri a cikin manya masu shekaru 80 zuwa sama.
Mai yiwuwa likitan lafiyar ku zai bada shawarar Shingrix akan Zostavax. Shingrix an ba da shawarar musamman ga marasa lafiya masu rigakafi tunda yana da rigakafin da ba a rayuwa. Tambayi likitan ku ko likitan kantin ku game da wane maganin rigakafin cutar shingles ya dace a gare ku.
Verageaukar hoto da kwatancen farashi na Shingrix vs. Zostavax
Ga manya ‘yan shekaru 50 zuwa sama, shirin kawai tare da ɗaukar hoto na Medicare Part D zai rufe alurar rigakafin Shingrix. Koyaya, har yanzu ana iya samun tara koda tare da ɗaukar hoto na Medicare Part D. Matsakaicin farashin tsabar kudi daya na Shingrix shine $ 167, kodayake kuna iya amfani da katin ragi na ragi don rage wannan kudin. Duba tare da kantin magani na gida don ganin idan zaka iya amfani da katin Shingrix SingleCare.
Kamar Shingrix, Zostavax an rufe shi da farko ta shirin Medicare Sashe na D ko tsare-tsaren Amfani da Medicare tare da ɗaukar Medicare Part D. Adana harajin Zostavax tare da inshora na iya bambanta. Tare da matsakaicin farashin kuɗi na $ 278, Zostavax na iya tsada tare da ko ba tare da inshora ba. Amfani da katin ragi na rangwame na Zostavax na iya iya rage wannan kuɗin.
| Shingrix | Zostavax | |
| Yawanci inshora ke rufe shi? | Ee | Ee |
| Yawanci an rufe shi ta Medicare Part D? | Ee | Ee |
| Daidaitaccen sashi | Allura 1 (0.5 ml) sannan wani allurar (0.5 ml) bayan watanni 2 zuwa 6 | 1 allurai guda ɗaya (0.65 ml) |
| Hanyar biyan kuɗaɗe na Medicare | $ 0– $ 164 | $ 0– $ 237 |
| SingleCare kudin | $ 155 + | N / A |
Illolin gama gari na Shingrix vs. Zostavax
Abubuwan da suka fi dacewa na Shingrix da Zostavax sun haɗa da halayen a wurin allurar. Bayan allurar Shingrix ko Zostavax, ƙila ku sami ciwo, ja, ko kumburi kewaye da wurin allurar. Hakanan zaka iya jin zafi ko ƙaiƙayi kewaye da yankin allurar.
Idan aka kwatanta da Zostavax, an bayar da rahoton Shingrix don haifar da ƙarin halayen jiki kamar ciwon kai, zazzabi, ciwon tsoka (myalgia), da gajiya. Duk da yake waɗannan tasirin na iya zama damuwa, yawanci suna da sauƙi kuma suna ɓacewa da kansu.
| Shingrix | Zostavax | |||
| Sakamakon sakamako | Ana amfani? | Mitar lokaci | Ana amfani? | Mitar lokaci |
| Redness a wurin allura | Ee | 39% | Ee | 36% |
| Jin zafi a wurin allura | Ee | 86% | Ee | 3. 4% |
| Kumburi a wurin allurar | Ee | 29% | Ee | 26% |
| Yin ƙaiƙayi a wurin allurar | Ee | kashi biyu | Ee | 7% |
| Ciwon kai | Ee | Hudu. Biyar | Ee | 1% |
| Zazzaɓi | Ee | 26% | Ee | kashi biyu |
| Ciwon tsoka | Ee | 53% | Ba | * |
| Gajiya | Ee | 51% | Ba | * |
* ba'a ruwaito ba
Mitar ba ta dogara da bayanai daga gwajin kai-da-kai. Wannan na iya zama ba cikakken jerin tasirin illa bane wanda zai iya faruwa. Da fatan za a koma zuwa likitanku ko mai ba da sabis na kiwon lafiya don ƙarin koyo.
Source: DailyMed (Shingrix) , DailyMed (Zostavax)
Magungunan ƙwayoyi na Shingrix vs. Zostavax
Magungunan rigakafi kamar cyclosporine da tacrolimus na iya rage tasirin alluran. Magunguna, kamar prednisone, da chemotherapy kuma suna iya samun tasirin rigakafi wanda zai iya canza yadda alluran ke aiki.
Waɗanda ke kan rigakafin rigakafi ya kamata su guji Zostavax gaba ɗaya; Zostavax yana dauke da kwayar cutar mai rai, wanda zai iya haifar da kamuwa da cuta.
Magungunan rigakafin cutar kamar acyclovir da famciclovir na iya tsoma baki tare da tasirin allurar rigakafin Zostavax. Kwamitin Ba da Shawara kan Aiwatar da rigakafin rigakafi (ACIP) ya ba da shawarar cewa mutanen da ke shan kwayar rigakafin cutar su daina shan magungunan cutar 24 hours kafin samun maganin Zostavax. Bai kamata a ci gaba da jiyya tare da magungunan ƙwayoyin cuta ba aƙalla kwanaki 14 bayan yin rigakafin tare da Zostavax.
| Drug | Ajin Magunguna | Shingrix | Zostavax |
| Cyclosporine Tacrolimus Prednisone Chemotherapy | Magungunan rigakafi na rigakafi | Ee | Ee |
| Acyclovir Valacyclovir Famciclovir | Ma'aikatan rigakafin cutar | Ba | Ee |
Tuntuɓi ƙwararren masanin kiwon lafiya don sauran hanyoyin hulɗa da ƙwayoyi
Gargadi na Shingrix da Zostavax
Shingrix da Zostavax na iya haifar da laulayi, ko rashin lafiyan, halayen waɗanda ke tare da rashin lafiyan kayan aikin rigakafin. Zostavax na iya haifar da halayen rashin lafiyan mai tsanani a cikin waɗanda ke da sananniyar rashin lafiyar gelatin ko neomycin. Matsanancin rashin lafiyan jiki na iya haifar da mummunan kurji da matsalar numfashi (anaphylaxis).
Ya kamata a guji Zostavax a cikin waɗanda ke ɗaukar wakilan rigakafin rigakafi da waɗanda ke fama da yanayin kiwon lafiya waɗanda ke raunana garkuwar jiki.
Tambayi likitanku ko likitan magunguna game da wasu abubuwan kiyayewa kafin yin rigakafin shingles.
Tambayoyi akai-akai game da Shingrix vs. Zostavax
Menene Shingrix?
Shingrix is a rigakafin rigakafi amfani da shi don hana zafin kamuwa da cuta, ko shingles, a cikin manya masu shekara 50 ko sama da haka. An amince da shi a cikin 2017, Shingrix alurar rigakafi ce wacce ba ta dauke da kwayar cutar varicella-zoster mai rai. Ana gudanar da shi a cikin allurai biyu tare da watanni biyu zuwa shida a tsakanin kashi na farko da na biyu. Kamfanin GlaxoSmithKline ne ya ƙera Shingrix.
Menene Zostavax?
Zostavax rigakafin cututtukan zoster ne wanda aka yarda dashi a shekara ta 2006. A matsayinshi na rigakafin rayayyiyar rayuwa, Zostavax yana dauke da rayayyen sigari, mai rauni na kwayar cutar ta varicella-zoster. Ana amfani da Zostavax a cikin kashi ɗaya a cikin manya masu shekaru 50 ko sama da hakan. Kamfanin Merck ne ke ƙera shi
Shin Shingrix da Zostavax iri ɗaya ne?
Dukansu Shingrix da Zostavax na iya rage haɗarin shingles. Koyaya, sun bambanta cikin tasiri, gudanarwa, da kuma illa masu illa. Shingrix shine maganin rigakafin sake dawowa kuma Zostavax rigakafin rayuwa ne. Ma'ana, Shingrix yana dauke da wani nau'i wanda ba shi da amfani na kwayar cutar varicella-zoster kuma Zostavax yana dauke da kwayar mai rai mai rauni, mai rauni. Wani bambancin shine cewa ana yiwa Shingrix allura a cikin tsoka yayin da allurar Zostavax take ƙarƙashin ƙirar. Idan aka kwatanta da Zostavax, Shingrix sabuwar rigakafin shingles ce.
Shin Shingrix ko Zostavax sun fi kyau?
Shingrix ya fi Zostavax tasiri. Shingrix yana da tasiri 97% wajen hana shingles a cikin manya masu shekaru 50 zuwa 69 yayin da Zostavax kawai 70% ne ke da tasiri wajen hana shingles a cikin ƙungiyar masu shekaru. Shingrix koyaushe yana hana shingles a cikin tsofaffi yayin da tasirin Zostavax ya ragu tare da ƙaruwa. Koyaya, Shingrix yana da sakamako mai illa na tsari fiye da Zostavax.
Shin zan iya amfani da Shingrix ko Zostavax yayin da nake da juna biyu?
Cibiyoyin Kula da Rigakafin Cututtuka (CDC) ba da shawarar Shingrix ko Zostavax a cikin mata masu ciki. Babu wadatattun karatu don tantancewa safety of Shingrix ko Zostavax a cikin mata masu ciki . Tuntuɓi likitanku ko mai ba da sabis na kiwon lafiya kafin yin rigakafin shingles.
Zan iya amfani da Shingrix ko Zostavax tare da barasa?
Shan barasa baya canza tasirin Shingrix ko Zostavax. Yana da haɗari a sha cikin matsakaici bayan yin rigakafin tare da allurar shingles.
Har yaushe maganin alurar rigakafi na Shingrix zai kare?
Gwajin gwaji ya nuna cewa Shingrix ya kasance yana aiki aƙalla aƙalla shekaru huɗu bayan kashi na biyu. An ba da shawarar cewa Shingrix ya ma fi wancan tsayi. Har yanzu, ana gudanar da ƙarin nazarin akan tasirin Shingrix na dogon lokaci.
Har yaushe ingancin aikin Zostavax?
Kariya daga shingles yana wanzuwa shekaru biyar bayan rigakafin tare da Zostavax . Bayan shekaru biyar, tasirin Zostavax na iya raguwa akan lokaci. CDC tana bada shawarar samun sabon allurar rigakafin shingles, Shingrix, koda kuwa kun riga kun karɓi allurar rigakafin Zostavax a baya.
Menene zai faru idan ba ku sami harbi na Shingrix na biyu ba?
Harbi na biyu na Shingrix yana da mahimmanci don tabbatar da cikakken kariya tare da allurar rigakafin. Koyaya, ba kwa buƙatar damuwa idan sama da watanni shida sun shude kafin karɓar harbi mai ƙarfi. Kawai ka tabbata ka karɓi harbi na biyu kusa da lokacin aikin wata biyu zuwa shida kamar yadda ya kamata.
