Protonix vs. Nexium: Bambanci, kamanceceniya, kuma wanene yafi muku alheri
Magunguna vs. AbokiBayanin magunguna & manyan bambance-bambance | Yanayin da aka bi | Inganci | Inshorar inshora da kwatancen farashi | Sakamakon sakamako | Hadin magunguna | Gargadi | Tambayoyi
Protonix (pantoprazole) da Nexium (esomeprazole) magunguna ne guda biyu da ake amfani dasu don magance matsalolin hanyar narkewar abinci, irin su gastroesophageal reflux disease (GERD). GERD wani yanayi ne mai ɗorewa wanda ke tasowa lokacin da ruwan ciki na yau da kullun ya koma cikin esophagus daga ciki. Wannan na iya haifar da bayyanar cututtuka kamar ƙwannafi da kuma rikitarwa masu tsanani irin su erosive esophagitis.
Dukansu Protonix da Nexium ɓangare ne na ajin magungunan da ake kira proton pump inhibitors (PPIs). Suna aiki ta hanyar toshe famfunan proton a cikin ciki, waɗanda ke da alhakin samar da acid. A zahiri, Protonix da Nexium suna taimakawa rage yawan samar da acid a cikin ciki.
Menene manyan bambance-bambance tsakanin Protonix da Nexium?
Protonix, wanda Pfizer ya ƙera, shine sunan suna na pantoprazole. Magungunan magani ne wanda ake amfani dashi don magance cututtukan cututtukan yara da ke cikin manya da yara yan shekaru 5 zuwa sama. Akwai shi azaman 20 MG da 40 MG jinkirin-saki kwamfutar hannu, da kuma 40 mg ruwa dakatar. A wasu lokuta, ana iya yin amfani da Protonix azaman allurar cikin jijiya (IV).
Nexium AstraZeneca ne ya ƙera shi kuma shine sunan suna esomeprazole. Ana samunsa azaman magani ko kantin sayar da magani (OTC) wanda ake amfani dashi don magance GERD a cikin manya, yara, da jarirai masu shekaru 1 zuwa sama. Ba kamar Protonix ba, Nexium ya zo a matsayin 20 MG da 40 MG jinkirta-saki kwantena. Nexium kuma ana samun shi azaman 2.5 mg, 5 mg, 10 mg, 20 mg, da 40 mg ruwa dakatar.
| Babban bambance-bambance tsakanin Protonix da Nexium | ||
|---|---|---|
| Protonix | Nexium | |
| Ajin magani | Proton famfo mai hanawa (PPI) | Proton famfo mai hanawa (PPI) |
| Alamar alama / ta kowa | Nau'i da nau'ikan sigar akwai | Nau'i da nau'ikan sigar akwai |
| Menene sunan gama-gari? | Pantoprazole | Esomeprazole |
| Wani nau'i (s) ne miyagun ƙwayoyi ya shigo? | Tabletaddamar da fitarwa Granules fakiti don dakatar da ruwa Cikin hanji don allura | Jigilar fitowar jinkiri Granules fakiti don dakatar da ruwa Cikin hanji don allura |
| Menene daidaitaccen sashi? | 40 MG sau ɗaya a rana | 20 ko 40 MG sau ɗaya a rana |
| Yaya tsawon maganin al'ada? | Har zuwa sati 8 | 4 zuwa 8 makonni dangane da yanayin da ake bi da shi |
| Wanene yawanci yake amfani da magani? | Manya da yara masu shekaru 5 zuwa sama | Manya, yara, da jarirai masu shekara 1 zuwa sama |
Yanayin da Protonix da Nexium suka bi da shi
Protonix da Nexium duk suna iya magance GERD da yanayin da ke tattare da GERD, kamar su reflux acid (ƙwannafi). Dukkanin magunguna guda biyu kuma an yarda da FDA don magance cututtukan ciki mai saurin narkewa, ko ƙonewar layin esophagus.
Nexium kuma an yarda da FDA don magance cutar Helicobacter pylori (H. pylori). Wannan nau'in kamuwa da cuta yana tasowa lokacin da kwayoyin H. pylori suka kamu da hanyar narkewar abinci, wanda zai haifar da ulcers. Bayan ulcers wanda H. pylori ya haifar, Nexium na iya hana haɗarin miki da ke haɗuwa da cututtukan cututtukan cututtukan nonsteroidal (NSAIDs).
Dukansu Protonix da Nexium ana iya amfani dasu don kula da yanayin keɓaɓɓu, kamar cutar Zollinger-Ellison. Wadannan yanayi ana yin su ne ta hanyar yawan fitar da ruwan ciki. Hakanan ana iya amfani da Protonix da Nexium don magance ulcer, wanda ya ƙunshi duka duodenal da ulcer.
Protonix da Nexium kawai ana ba da shawarar don amfani da gajeren lokaci, ko har zuwa makonni takwas a mafi yawan lokuta.
| Yanayi | Protonix | Nexium |
| Ciwon reflux na Gastroesophageal (GERD) | Ee | Ee |
| Ciwon esophagitis | Ee | Ee |
| Yanayin sirri | Ee | Ee |
| H. pylori kamuwa da cuta | Kashe-lakabi | Ee |
| Rage kasadar cututtukan ciki masu nasaba da NSAID | Kashe-lakabi | Ee |
| Duodenal ulcers | Kashe-lakabi | Kashe-lakabi |
| Ciwon ciki | Kashe-lakabi | Kashe-lakabi |
| Bwannafi | Kashe-lakabi | Ee |
Shin Protonix ko Nexium sun fi tasiri?
Gwajin gwaji ya nuna cewa pantoprazole da esomeprazole suna da tasiri iri ɗaya. Trialaya daga cikin gwaji na asibiti idan aka kwatanta tasirin na 40 MG na pantoprazole zuwa 40 MG na esomeprazole a marasa lafiya tare da GERD. Kimanin marasa lafiya 580 bazuwar su don karɓar ko dai pantoprazole ko esomeprazole sama da makonni 4, 8, ko 12 na jiyya. An sami cikakkiyar gafarar GERD tare da duka PPI a irin wannan ƙimar.
A cikin bazuwar, gwaji na asibiti mai makafi biyu, an kwatanta tasirin pantoprazole da esomeprazole don maganin GERD. Kimanin marasa lafiya 200 aka rarraba don karɓar 40 MG na pantoprazole kowace rana ko 40 MG na esomeprazole kowace rana. Dukansu PPIs an gano su zama daidai tasiri tare da aminci da haƙuri.
Tuntuɓi mai ba da lafiya don mafi kyawun zaɓin magani a gare ku. Mai ba da kulawarka na farko zai iya tura ka zuwa ga likita wanda ya ƙware a kan gastroenterology don ƙarin shawarar likita.
Verageaukar hoto da kwatancen farashi na Protonix vs. Nexium
Yawancin Medicare da tsare-tsaren inshora zasu rufe nau'ikan tsarin Protonix, pantoprazole. Kayan aikin likitanci na iya kaiwa daga $ 0 zuwa $ 17 don pantoprazole. Ba tare da inshora ba, farashin tsabar kuɗi na Protonix shine $ 522. Koyaya, tare da takaddar Protonix daga SingleCare, farashin kuɗin kusan $ 11.
Wasu Medicare da tsare-tsaren inshora na iya ɗaukar Nexium ko sigar jigilar ta, esomeprazole. Kayan aikin likita na esomeprazole na iya kaiwa daga $ 1 zuwa $ 41. Matsakaicin farashin farashin Nexium shine $ 478 dangane da yawa da ƙarfin da aka tsara. Tare da takaddar SingleCare Nexium, za a iya rage farashin zuwa dala 27.
| Protonix | Nexium | |
| Yawanci inshora ya rufe? | Ee, azaman jigilar fasali | Ee, azaman jigilar fasali |
| Yawanci an rufe shi ta Medicare Part D? | Ee, azaman jigilar fasali | Ee, azaman jigilar fasali |
| Yawan | 30 allunan (40 MG) | 30 allunan (40 MG) |
| Hanyar biyan kuɗaɗe na Medicare | $ 0 - $ 17 | $ 1 - $ 41 |
| SingleCare kudin | $ 11 + | $ 27 + |
Sakamakon illa na yau da kullun na Protonix vs. Nexium
Abubuwan da suka fi dacewa na Protonix sune ciwon kai, gudawa, tashin zuciya, ciwon ciki, amai, gas, jiri, da haɗin gwiwa.
Abubuwa masu illa na Nexium sun haɗa da ciwon kai, gudawa, jiri, jiri, ciwon ciki, maƙarƙashiya, da bushewar baki.
M sakamako masu illa na PPIs galibi ana haɗuwa da amfani na dogon lokaci. Babban sakamako mai illa na iya haɗawa da ɓarkewar ƙashi da ke da alaƙa da osteoporosis, rashi bitamin B12, da ƙananan matakan magnesium (hypomagnesemia).
| Protonix | Nexium | |||
| Sakamakon sakamako | Ana amfani? | Mitar lokaci | Ana amfani? | Mitar lokaci |
| Ciwon kai | Ee | 12% | Ee | ≥1% |
| Gudawa | Ee | 9% | Ee | ≥1% |
| Maƙarƙashiya | Ee | <2% | Ee | ≥1% |
| Bakin bushe | Ee | <2% | Ee | ≥1% |
| Ciwan | Ee | 7% | Ee | ≥1% |
| Ciwon ciki | Ee | 6% | Ee | ≥1% |
| Amai | Ee | 4% | Ee | <1% |
| Dizziness | Ee | 3% | Ee | <1% |
| Gas | Ee | 4% | Ee | ≥1% |
| Hadin gwiwa | Ee | 3% | Ba | - |
Mitar ba ta dogara da bayanai daga gwajin kai-da-kai. Wannan na iya zama ba cikakken jerin illolin da zasu iya faruwa ba. Da fatan za a koma zuwa likitanku ko mai ba da sabis na kiwon lafiya don ƙarin koyo.
Source: DailyMed ( Protonix ,, DailyMed ( Nexium )
Magungunan ƙwayoyi na Protonix vs. Nexium
Protonix da Nexium, kamar sauran PPIs, suna hulɗa tare da yawancin magunguna iri ɗaya. Wadannan PPIs ya kamata a kula ko a guji su da wasu magungunan da suka dogara da ƙoshin ciki don sha. Magungunan da suka dogara da ruwan ciki na ciki don sha sun hada da gishirin ƙarfe, erlotinib, ketoconazole, da mycophenolate mofetil.
Protonix da Nexium na iya yin ma'amala da magungunan rage kaifin cutar, ko magungunan da galibi ake amfani da su don magance cutar HIV. PPIs na iya ƙaruwa ko rage matakan jini na magungunan ƙwayoyin cuta, wanda zai iya haifar da haɗarin haɗari mai guba ko rage tasiri tare da magungunan antiretroviral.
Yin amfani da Protonix ko Nexium tare da warfarin na iya ƙara haɗarin zubar jini.
Nexium ya kamata a kula ko a guje shi tare da diazepam tunda yana iya ƙara matakan jini na diazepam kuma yana haifar da haɗarin mummunan sakamako. Amfani da Nexium da clopidogrel tare kuma ya kamata a guje su. Nexium na iya rage yadda clopidogrel ke aiki sosai a jiki, wanda hakan na iya ƙara haɗarin daskarewar jini.
| Drug | Nau'in magunguna | Protonix | Nexium |
| Atazanavir Rilpivirine Nelfinavir Saquinavir | Magungunan rigakafi | Ee | Ee |
| Ketoconazole | Antifungal | Ee | Ee |
| Ferrous sulfate Gishirin mai narkewa Ferrous fumarate | Gishirin ƙarfe | Ee | Ee |
| Mycophenolate mofetil Samun bayanai | Tsarin rigakafi | Ee | Ee |
| Erlotinib | Chemotherapy | Ee | Ee |
| Digoxin | Cardiac glycoside | Ee | Ee |
| Warfarin | Anticoagulant | Ee | Ee |
| Diazepam | Benzodiazepine | Ba | Ee |
| Clopidogrel | Antiplatelet | Ba | Ee |
Tuntuɓi ƙwararren masanin kiwon lafiya don sauran hanyoyin hulɗa da ƙwayoyi
Gargadi na Protonix da Nexium
Amfani da PPI na dogon lokaci na iya haifar da ƙarin haɗarin ɓarkewar ƙashi, musamman ga mutanen da aka riga aka bincikar su da osteoporosis. Mayarfin ma'adinai na ƙashi na iya buƙatar kulawa yayin jiyya na dogon lokaci tare da PPIs.
Wasu marasa lafiya sun sami mummunan ciwon nephritis (TIN) yayin shan Protonix ko Nexium. Ciwon ciki shine kumburin koda, wanda zai haifar da raguwar aikin koda.
Amfani da PPIs na iya haɗuwa da haɗarin haɗarin cututtukan Clostridium mai haɗari. Waɗanda ke fama da cutar gudawa na iya bukatar a saka musu ido, musamman a yanayin asibiti.
Shan Protonix ko Nexium na iya kara haɗarin ƙananan matakan jini na magnesium (hypomagnesemia) ko bitamin B12 (ƙarancin bitamin B12). Akwai haɗarin haɗarin hypomagnesemia da rashi bitamin B12 a cikin waɗanda ke cikin dogon magani tare da PPIs.
Tuntuɓi mai ba da lafiyar ku don ƙarin gargaɗi da kiyayewa kafin ɗaukar PPI.
Tambayoyi akai-akai game da Protonix vs. Nexium
Menene Protonix?
Protonix magani ne kawai na PPI wanda ake amfani dashi da farko don magance cututtukan erosive da ke haɗuwa da GERD. Protonix yana samuwa azaman kwamfutar hannu da aka jinkirta-fitarwa da dakatar da ruwa. Sunan Protonix na asali shine pantoprazole.
Menene Nexium?
Nexium magani ne na PPI wanda ake amfani dashi don magance cututtukan acid da ƙwannafi, da kuma haɗarin esophagitis hade da GERD. Akwai shi tare da takardar sayan magani ko kan kanti. Nexium da farko yana zuwa azaman kwantaccen jinkiri-fitarwa ko dakatar da ruwa. Sunan gaba daya na Nexium shine esomeprazole.
Shin Protonix da Nexium iri daya ne?
Protonix da Nexium sune magungunan PPI guda biyu waɗanda zasu iya magance GERD, yanayin tsinkaye, da ulcer. Koyaya, sun ƙunshi abubuwa masu aiki daban-daban kuma sun zo cikin tsari daban-daban. Protonix ya ƙunshi pantoprazole kuma Nexium ya ƙunshi esomeprazole. Protonix na iya yin maganin GERD a cikin manya da yara masu shekaru 5 zuwa sama yayin da Nexium na iya magance GERD a cikin manya, yara, da jarirai masu wata ɗaya zuwa sama.
Shin Protonix ko Nexium sun fi kyau?
Protonix da Nexium suna kama da tasiri. PPI mafi dacewa za a ƙaddara bisa la'akari da shekaru, yanayin kiwon lafiya, farashi, inshora, da sauran magunguna da ake sha.
Zan iya amfani da Protonix ko Nexium yayin da nake da juna biyu?
Protonix ko Nexium na iya zama lafiya a ɗauka yayin da suke ciki. Koyaya, yakamata ayi amfani dasu idan fa'idodin sun fi haɗarin haɗari. A halin yanzu, babu isasshen karatu da zai nuna cewa Protonix ko Nexium ba su da cikakkiyar lafiya don amfani a lokacin daukar ciki. Tuntuɓi mai ba da lafiya don shawarwarin likita kan mafi kyawun magani ga GERD yayin da take da juna biyu.
Zan iya amfani da Protonix ko Nexium tare da barasa?
Duk da yake ba a san barasa don yin hulɗa tare da Protonix ko Nexium ba, zai iya lalata haɓakar acid da alamun cututtukan zuciya a cikin wasu mutane. Yin amfani da barasa na iya zama mai aminci a daidaituwa yayin shan Protonix ko Nexium, amma ba a ba da shawarar gaba ɗaya ba.
Menene mafi ingancin mai hana ruwa mai hana ruwa gudu?
PPI mafi inganci zai dogara ne akan yanayin da ake bi, sashin PPI, da sauran magungunan da mutum zai sha. Hakanan yakamata a kula da farashin PPI yayin yanke shawara mafi inganci zaɓi.
Me zan iya ɗauka maimakon Nexium?
Nexium (esomeprazole) shine mai hana proton pump. Sauran masu hana ruwa gudu na proton sun hada da Prilosec (omeprazole), Prevacid (lansoprazole), Aciphex (rabeprazole), da Protonix (pantoprazole). Idan alamun GERD ba su inganta tare da PPI ba, mai ba da sabis na kiwon lafiya na iya bayar da shawarar maganin H2 toshe mai maimakon. Misalan masu toshe H2 sun hada da Pepcid (famotidine), Zantac (ranitidine), da Tagamet (cimetidine).
Shin Nexium na iya yin ɓarna?
Ana amfani da Nexium don magance haɓakar acid. Dakatar da maganin Nexium a baya fiye da shawarar da mai ba da sabis na kiwon lafiya na iya haifar da dawowar alamun bayyanar cututtuka. Nexium bazaiyi aiki iri ɗaya da kowa ba. Idan bayyanar cututtuka ba ta inganta tare da Nexium, ana iya ba da shawarar wasu zaɓuɓɓukan magani.
