Pantoprazole vs. omeprazole: Bambanci, kamanceceniya, kuma wanene yafi muku alheri
Magunguna vs. AbokiBayanin magunguna & manyan bambance-bambance | Yanayin da aka bi | Inganci | Inshorar inshora da kwatancen farashi | Sakamakon sakamako | Hadin magunguna | Gargadi | Tambayoyi
Pantoprazole da omeprazole su ne masu hana ruwa gudu na proton (PPIs) waɗanda ake amfani da su don magance yanayin narkewar abinci. Dukkanin kwayoyi guda biyu ana iya amfani dasu don cututtukan ciki na ciki (GERD), wani yanayi mai saurin ciwo, da ciwan esophagitis. Suna aiki ta hanyar rage ɓoyewar asid a cikin ciki. Yayinda pantoprazole da omeprazole sune magunguna iri ɗaya, suma suna da wasu bambance-bambance.
Menene manyan bambance-bambance tsakanin pantoprazole da omeprazole?
Pantoprazole (Pantoprazole takardun shaida) shine asalin sunan Protonix kuma a halin yanzu ana siyan shi tare da takardar sayan magani kawai. An yarda da FDA don kula da GERD a cikin manya da yara masu shekaru 5 zuwa sama don tsawan lokaci na kusan har zuwa makonni 8. Pantoprazole (karin bayanin Pantoprazole) an kawo shi azaman kwamfutar hannu da aka jinkirta-fitarwa ko dakatar da ruwa. Hakanan za'a iya yin shi azaman allurar jijiya (IV) a asibiti ko asibiti.
Omeprazole (Omeprazole takardun shaida) sanannen sanannen sunan sa, Prilosec, kuma ana iya siyan shi tare da takardar sayan magani ko kan kanti. Yana aiki kwatankwacin pantoprazole azaman PPI. Koyaya, kuma an yarda da FDA don magance ulcer, duwatalƙulen, cututtukan helicobacter pylori (H. pylori), da gyambon ciki tare da GERD da erosive esophagitis Omeprazole (ƙarin bayanan Omeprazole) na iya magance GERD a cikin manya da yara shekara 1 zuwa sama. Ya zo a matsayin jinkirin-saki kwantena, kwamfutar hannu, da ruwa dakatar.
| Babban bambance-bambance tsakanin pantoprazole da omeprazole | ||
|---|---|---|
| Pantoprazole | Omeprazole | |
| Ajin magani | Proton famfo mai hanawa (PPI) | Proton famfo mai hanawa (PPI) |
| Alamar alama / ta kowa | Ana samun wadataccen tsari | Ana samun wadataccen tsari |
| Menene sunan gama-gari? Menene sunan alamar? | Pantoprazole Protonix | Omeprazole Rariya |
| Wani nau'i (s) ne miyagun ƙwayoyi ya shigo? | Rubutun baka, jinkirta-saki Dakatar da baka IV allura / jiko | Rubutun baka, jinkirta-saki Maganin baka, jinkirta-saki Dakatar da baka IV allura / jiko |
| Menene daidaitaccen sashi? | 40 MG sau ɗaya a rana | 20 MG sau ɗaya a rana |
| Yaya tsawon maganin al'ada? | Har zuwa sati 8 | 4 zuwa 8 makonni |
| Wanene yawanci yake amfani da magani? | Manya da yara 'yan shekara 5 zuwa sama | Manya da yara shekara 1 zuwa sama |
Yanayin da pantoprazole da omeprazole suka kula dashi
Pantoprazole da omeprazole duka an yarda da FDA don magance cututtukan zuciya daga GERD da erosive esophagitis. PPIs kamar pantoprazole da omeprazole sun fi ƙarfin antacids na yau da kullun, kamar masu toshewar histamine (H2). Yawancin lokaci ana tsara su don magani na gajeren lokaci ba zai wuce sati 8 ba.
Pantoprazole da omeprazole kuma suna iya magance yanayin keɓaɓɓen yanayin da ke sa ciki ya samar da ruwan ciki mai yawa. Ciwon Zollinger-Ellison wani yanayi ne wanda zai iya haifar da ɓarkewar acid kuma ya haɗa da ƙari a cikin ƙangar jikin mutum ko duodenum (ɓangaren farko na ƙaramar hanji).
Pantoprazole da omeprazole na iya taimakawa wajen magance wasu yanayi kamar gyambon ciki na duodenal, gyambon ciki ko na ciki, da ulcer. Wadannan cututtukan ulce yawanci suna faruwa ne ta hanyar kamuwa daga wata kwayar cuta mai suna H. pylori. Yayinda aka yarda omeprazole ya bi da H. pylori tare da wasu magunguna, ana amfani da pantoprazole a kashe lakabin wannan cutar kuma.
Sauran kashe-lakabin amfani ga duka kwayoyi sun hada da cutar Barrett da ulcers wanda ya samo asali daga amfani da kwayoyin anti-inflammatory marasa steroid (NSAIDs).
| Yanayi | Pantoprazole | Omeprazole |
| Cutar Reflux na Gastroesophageal (GERD) | Ee | Ee |
| Ciwon Esophagitis | Ee | Ee |
| Ciwon Zollinger-Ellison | Ee | Ee |
| Yanayin sirri | Ee | Ee |
| Duodenal ulcers | Kashe-lakabi | Ee |
| Ciwon ciki | Kashe-lakabi | Ee |
| H. Pylori kamuwa da cuta | Kashe-lakabi | Ee |
| Barrett ta kamu | Kashe-lakabi | Kashe-lakabi |
| Rashin narkewar abinci | Kashe-lakabi | Kashe-lakabi |
| NSAID ya haifar da ulcers | Kashe-lakabi | Kashe-lakabi |
| Ciwon ultic | Kashe-lakabi | Kashe-lakabi |
Kuna son mafi kyawun farashi akan Omeprazole?
Yi rajista don faɗakarwar farashin Omeprazole kuma gano lokacin da farashin ya canza!
Sami faɗakarwar farashi
Shin pantoprazole ko omeprazole sun fi tasiri?
Pantoprazole da omeprazole sun nuna suna da tasiri wajen magance GERD. A cikin wani meta-bincike wanda ya tattara sama da 40 daban-daban karatu, sakamakon bai sami wani bambance-bambance mai mahimmanci ba game da tasiri tsakanin PPIs. An sami Pantoprazole yayi tasiri daidai da omeprazole. Wasu gwaje-gwajen asibiti masu makafi biyu suma sun hada da sauran PPIs kamar su Nexium (esomeprazole) , lansoprazole (Prevacid), da rabeprazole (Aciphex).
Daya karatu an haɗa su a cikin meta-bincike sun gano cewa pantoprazole ya fi omeprazole tasiri wajen magance gyambon ciki. Sakamakon da aka tattara daga nazarin 5 a cikin tasirin nazarin sake dubawa akan ƙimar warkarwa. Duk da yake an gano pantoprazole ya zama mai tasiri sosai, akwai yuwuwar akwai kurakurai tare da yin allura daidai wa daida.
Pantoprazole da omeprazole duka magunguna ne masu kamanta dangane da inganci. Mayaya za a iya fifita shi akan ɗayan dangane da yanayin da ake bi da shi da kuma kuɗin magani. Tuntuɓi likita don sanin wane PPI na iya zama mafi kyau na ki.
Verageaukar hoto da kwatancen farashi na pantoprazole vs. omeprazole
Pantoprazole magani ne na yau da kullun wanda yawancin Medicare ke rufe shi kuma mafi yawan tsare-tsaren inshora. Matsakaicin farashin sayar da pantoprazole yana kusan $ 522. Kuna iya samun damar adana ƙarin tare da takaddun SingleCare wanda zai iya kawo kuɗin ƙasa zuwa $ 28.
Nemi katin rangwame na SingleCare
Omeprazole magani ne mai mahimmanci wanda yawancin Medicare ke rufe shi kuma mafi yawan tsare-tsaren inshora. Matsakaicin farashin ɗan kasuwa na omeprazole yana kusan $ 67.99. Tare da takaddun SingleCare zaka iya tsammanin biya kusan $ 9-20 don 30, 20mg capsules.
| Pantoprazole | Omeprazole | |
| Yawanci inshora ya rufe? | Ee | Ee |
| Yawanci Medicare ke rufe shi? | Ee | Ee |
| Daidaitaccen sashi | 40 MG (adadin 30) | 20 MG (adadin 30) |
| Hanyar biyan kuɗaɗe na Medicare | Dogaro da tsarin inshorar ku | Dogaro da tsarin inshorar ku |
| SingleCare kudin | $ 28 | $ 9-20 |
Sakamakon illa na yau da kullun na pantoprazole da omeprazole
Pantoprazole da omeprazole na iya haifar da illa kamar ciwon kai, jiri, jiri, da amai. Hakanan suna iya haifar da wasu sakamako masu illa na ciki kamar su gudawa, maƙarƙashiya, ciwon ciki ko na ciki, da yawan kumburi ko iskar gas. Sauran cututtukan da ke tattare da juna na iya haɗawa da ciwon haɗin gwiwa, cututtukan sashin jiki na sama, da asthenia ko rashin ƙarfi.
Omeprazole kuma na iya haifar da sakamako masu illa kamar sake gyaran acid, ciwon baya, da tari. Ba a yi nazarin Pantoprazole ba don nuna waɗannan tasirin na musamman kamar sau da yawa.
| Pantoprazole | Omeprazole | |||
| Tasirin Side | Ana amfani? | Mitar lokaci | Ana amfani? | Mitar lokaci |
| Ciwon kai | Ee | 12.2% | Ee | 7% |
| Ciwan | Ee | 7% | Ee | 4% |
| Gudawa | Ee | 8.8% | Ee | 4% |
| Maƙarƙashiya | Ee | <2% | Ee | kashi biyu |
| Ciwon ciki | Ee | 6.2% | Ee | 5% |
| Amai | Ee | 4.3% | Ee | 3% |
| Ciwan ciki | Ee | 3.9% | Ee | 3% |
| Dizziness | Ee | 3% | Ee | kashi biyu |
| Hadin gwiwa | Ee | 2.8% | Ee | N / A |
| Rash | Ee | <2% | Ee | kashi biyu |
| Acid regurgitation | Ba | - | Ee | kashi biyu |
| Babban kamuwa da cuta na numfashi | Ee | N / A | Ee | kashi biyu |
| Rauni / Rashin ƙarfi | Ee | N / A | Ee | 1% |
| Ciwon baya | Ba | - | Ee | 1% |
| Tari | Ba | - | Ee | 1% |
* Nemi likita ko likitan magunguna don duk illolin da zasu iya haifarwa.
Source: DailyMed (pantoprazole) , DailyMed (omeprazole)
Magungunan ƙwayoyi na pantoprazole da omeprazole
Dukansu pantoprazole da omeprazole na iya ma'amala da kwayoyi iri ɗaya. Dukansu na iya yin hulɗa tare da magungunan ƙwayar cuta kamar su rilpivirine, atazanavir, da saquinavir. Shan waɗannan magunguna tare na iya canza tasirin maganin rigakafin ƙwayar cuta da ƙara yawan gubarsa. Shan pantoprazole ko omeprazole tare da warfarin na iya kara saurin zub da jini. Saboda haka, kada a tafi tare. Duk da yake clotopidogrel bazai iya shafar pantoprazole ba, yakamata a kiyaye shi da omeprazole.
Pantoprazole da omeprazole suna hulɗa tare da methotrexate, maganin antimetabolite, kuma suna iya haifar da haɗarin yawan guba da illa mai illa.
Pantoprazole da omeprazole bai kamata a sha su a lokaci guda da gishirin ƙarfe da sauran magungunan da suka dogara da ruwan ciki don sha. Sauran magungunan da suka dogara da sinadarin ciki don sha, sun hada da magunguna na chemotherapy kamar erlotinib da dasatinib da antifungals kamar ketoconazole da itraconazole.
Saboda duka PPIs suna haɗuwa a cikin hanta, suna iya yin hulɗa tare da wasu magunguna waɗanda ake sarrafa su ta hanyar irin wannan enzymes, gami da enzyme na CYP2C19. Koyaya, a cewar Alamar FDA , wasu daga cikin wadannan kwayoyi, gami da phenytoin, citalopram, da diazepam, ba a nuna suna da muhimmiyar mu'amala da pantoprazole ba. Har yanzu, yana da mahimmanci a tattauna kowane irin magani da zaku sha tare da likita kafin ɗaukar PPI.
PPIs na iya shafar sakamakon wasu gwaje-gwajen gwaje-gwaje. PPIs sanannu ne don haifar da sakamako mara kyau don gwajin fitsari na THC.
| Drug | Ajin Magunguna | Pantoprazole | Omeprazole |
| Rilpivirine Nelfinavir Atazanavir Saquinavir Ritonavir | Magungunan rigakafi | Ee | Ee |
| Warfarin | Anticoagulant | Ee | Ee |
| Clopidogrel | Antiplatelet | Ba | Ee |
| Samun bayanai | Antimetabolite | Ee | Ee |
| Mycophenolate mofetil Tacrolimus | Tsarin rigakafi | Ee | Ee |
| Ketoconazole Itraconazole Voriconazole | Antifungal | Ee | Ee |
| Erlotinib Dasatinib Nilotinib | Chemotherapy | Ee | Ee |
| Ferrous fumarate Gishirin mai narkewa Ferrous sulfate Ferrous succinate | Gishirin ƙarfe | Ee | Ee |
| Diazepam Midazolam | Benzodiazepine | Ba | Ee |
| Phenytoin | Antiepileptic | Ba | Ee |
| Clarithromycin Rifampin | Maganin rigakafi | Ee | Ee |
| Citalopram | Mai zaɓin maganin serotonin reuptake (SSRI) antidepressant | Ba | Ee |
| St. John’s Wort | Ganye | Ee | Ee |
* Wannan bazai zama cikakken jerin duk ma'amalar maganin miyagun ƙwayoyi ba. Tuntuɓi likita tare da duk magungunan da za ku iya sha.
Gargadi na pantoprazole da omeprazole
Ba a ba da shawarar Pantoprazole da omeprazole don amfani na dogon lokaci. An haɗu da amfani na dogon lokaci tare da kara kasadar kasusuwa . Idan kuna da cutar sanyin kashi, kuna so ku saka idanu kan duk wani amfani da PPIs.
Wasu bayanai sun ba da shawarar cewa magungunan PPI na iya ƙara haɗarin abubuwan da suka shafi zuciya da zuciya kamar zuciya da bugun jini. Koyaya, FDA da sauran rahotanni ƙarfafa fa'idodin abubuwan PPI sun fi wannan haɗarin nauyi.
Saboda ana sarrafa pantoprazole da omeprazole a cikin hanta, ana iya daidaita su ko a guje su cikin waɗanda ke da larurar hanta.
Pantoprazole da omeprazole na iya kara tsanantawa ko ƙara haɗarin cutar lupus erythematosus, wata cuta mai saurin kamuwa da jiki.
Jiyya tare da PPIs na iya ƙara haɗarin gudawa daga cututtukan Clostridium mai wahala. Wannan haɗarin na iya zama mafi girma ga waɗanda ke kwance a asibiti na dogon lokaci.
Dukkanin pantoprazole da omeprazole suna cikin Nauyin Ciki kuma yana iya haifar da lahani ga jaririn da ba a haifa ba. Tuntuɓi likita ko mai ba da kiwon lafiya idan kuna da ciki ko shayarwa.
Tambayoyi akai-akai game da pantoprazole da Omeprazole
Menene pantoprazole?
Pantoprazole (Protonix) shine proton pump inhibitor (PPI) magani wanda aka tsara don maganin GERD da erosive esophagitis. Ana ɗauka sau da yawa azaman 40 mg jinkirin-saki kwamfutar har zuwa makonni 8. Ana iya ɗaukar shi cikin manya da yara shekaru 5 zuwa sama.
Menene omeprazole?
Omeprazole (Prilosec) magani ne na PPI da aka tsara don kula da GERD da gurɓataccen esophagitis. Hakanan an yarda da FDA don kamuwa da H. pylori da duodenal ko ulcer. Ana iya ɗauka azaman 20 mg jinkirta-fitowar kwantena na makonni 4 zuwa 8 a cikin manya da yara shekara 1 zuwa sama.
Shin pantoprazole da omeprazole iri daya ne?
Pantoprazole da omeprazole suna cikin aji iri na magunguna. Koyaya, suna da amfani daban daban da aka yarda dasu da kuma illa masu illa. Hakanan suna zuwa cikin tsari da tsari daban-daban.
Shin pantoprazole ko omeprazole ya fi kyau?
Pantoprazole da omeprazole duk suna da tasiri ga GERD da kumburin ciki esophagitis. Mayaya daga cikin magungunan PPI za a iya fifita shi a kan ɗayan dangane da yanayin da ake bi da shi da kuma kuɗin maganin.
Zan iya amfani da pantoprazole ko omeprazole yayin da nake da juna biyu?
Ba a ba da shawarar Pantoprazole da omeprazole a cikin mata masu ciki saboda haɗarin cutarwar tayi. Koyaya, a wasu yanayi, fa'idodin na iya wuce haɗarin. Tuntuɓi likita idan kuna da ciki.
Zan iya amfani da pantoprazole ko omeprazole tare da barasa?
Shan barasa na iya kara wasu illolin da ke tattare da pantoprazole ko omeprazole. Saboda ciwon kai da tashin zuciya abubuwa ne na yau da kullun na abubuwan PPIs, waɗannan illolin na iya tsananta yayin da aka ɗauki PPIs da giya.
Shin OTC omeprazole ɗaya ne da takardar sayan magani?
Over-the-counter (OTC) omeprazole ya ƙunshi irin wannan magani da ƙarfin maganin omeprazole. Ana iya samun OTC omeprazole a matsayin OTC Prilosec a cikin samarwar kwanaki 14 na 20 mg Allunan. Bai kamata a dauki wannan kwas din magani ba fiye da sau daya a kowane watanni 4.
Shin ya kamata in sha Pantoprazole da Omeprazole a lokaci guda?
Kada a sha Pantoprazole da omeprazole a lokaci guda. Suna aiki ta hanyoyi iri ɗaya ta hanyar dakatar da samar da ruwan ciki a ciki. Haɗasu tare na iya ƙara haɗarin illa.
