Main >> Magunguna Vs. Aboki >> Metoprolol vs. atenolol: Bambanci, kamance, kuma wanne ne mafi alheri a gare ku

Metoprolol vs. atenolol: Bambanci, kamance, kuma wanne ne mafi alheri a gare ku

Magunguna vs. Aboki

Ana amfani da Metoprolol da atenolol wajen maganin nau'ikan yanayi masu nasaba da zuciya da suka hada da angina pectoris da hauhawar jini, ko hawan jini. Angina pectoris yana nufin yanayin da kake jin zafi na kirji ko rashin jin daɗi wanda ya kasance saboda zuciyarka ba ta karɓar isasshen jini mai wadataccen oxygen. Wannan na iya yiwuwa ya faru yayin lokacin babban damuwa ko aiki. Hawan jini yana nufin samun cutar hawan jini inda jinin da yake gudana ta jijiyoyinku yake sama da yadda yake a al'ada.

Metoprolol da atenolol suna cikin ajin magani iri ɗaya kuma suna bi da irin wannan yanayin, amma kuma akwai wasu bambance-bambance tsakanin waɗannan magungunan, kuma zamu tattauna waɗannan a nan.

Menene manyan bambance-bambance tsakanin metoprolol da atenolol?

Metoprolol magani ne kawai-wanda aka tsara azaman mai zaɓin beta-1 mai zaɓar adonergic agonist, in ba haka ba ana kiransa beta blockers. Masu karɓar Beta 1 suna da alhakin motsawar zuciya wanda ke haifar da ƙara ƙarfin zuciya da ƙarar ƙarfi na tsokawar zuciya. Toshe waɗannan masu karɓar rarar, kamar yadda metoprolol keyi, yana haifar da saurin bugun zuciya da ƙarancin ƙarfi. Metoprolol yana da ma'anar zuciya kuma yana iya shafar masu karɓar beta 1 kawai a cikin zuciya, kuma yana da ƙarancin shafar wasu nau'ikan masu karɓar beta da ke cikin jiki duka, kamar cikin hanyoyin iska.

Ana samun Metoprolol a cikin fitowar nan take a cikin 25 mg, 37.5 mg, 50 mg, 75 mg, da 100 mg mg. Sanarwa ta gaba ɗaya sanannen sanannen abu ne kamar metoprolol tartrate. Sigar da aka shimfiɗa na metoprolol, wanda aka sani da metoprolol succinate, ana samunsa cikin ƙarfin 25 MG, 50 MG, 100 MG, da 200mg. Ana samun capsules da aka faɗaɗa a cikin ƙarfi kamar na allunan. Hakanan akwai maganin allura 1 mg / ml tare da hoda na bakin. Rabin rayuwar metoprolol tartrate ya kai kimanin awanni uku, kuma rabin rayuwar metoprolol succinate yana da awanni bakwai. Wannan yana nufin ba dole ne a theirƙiri releaseirƙirar fitowar-sakin kamar sau da yawa.

Atenolol kuma magani ne na likitanci wanda aka ƙaddara shi azaman mai zaɓi beta-1-mai zaɓar adrenergic agonist. Yana aiki daidai da metoprolol a jiki. Rabin rabin atenolol yana kusan awa shida zuwa bakwai, sabili da haka na iya ɗaukar tsawon lokaci fiye da wasu ƙwayoyin metoprolol. Ana samun Atenolol a cikin 25 MG, 50 MG, da kuma 100 mg mg.

Babban bambance-bambance tsakanin metoprolol da atenolol
	Metoprolol	Atenolol
Ajin magani	Cardioselective beta-1-zabe adrenergic agonist (beta toshe)	Cardioselective beta-1-zabe adrenergic agonist (beta toshe)
Alamar alama / ta kowa	Brand da kuma janar akwai	Brand da kuma janar akwai
Menene sunan alamar?	Mai Talla, Toprol XL	Tenormin
Wani nau'i (s) ne miyagun ƙwayoyi ya shigo?	Nan da nan daɗaɗa-fitowar allunan baka da kawunansu, maganin injecti, foda ta baka	Nan da nan-fito da allunan baka
Menene daidaitaccen sashi?	50 MG sau biyu a rana	50 MG sau ɗaya a rana
Yaya tsawon maganin al'ada?	Dogon lokaci	Dogon lokaci
Wanene yawanci yake amfani da magani?	Yara da manya	Yara da manya

Yanayin da metoprolol da atenolol suka bi da shi

Metoprolol da atenolol duka ana amfani dasu wajen maganin angina pectoris da hauhawar jini. Ana iya amfani da su a cikin angina na yau da kullun, ko angina mara ƙarfi. Kwanan lokaci, daidaitaccen angina yana faruwa a bayyane lokacin da kake yin ƙoƙari na jiki ko kuma kuna cikin damuwa mai yawa. Mutuwar angina ba abune wanda ake iya faɗi ba kuma yana iya faruwa koda hutawa ne.

Lokacin amfani da shi wajen maganin hauhawar jini, ana iya amfani da metoprolol da atenolol shi kaɗai ko kuma a haɗe tare da wasu magungunan hawan jini. Lokacin da aka yi amfani da waɗannan ƙwayoyin a cikin shirin magani don aiki, da ake zargi, ko tabbatar da ɓarkewar ƙwayoyin cuta, ko bugun zuciya, suna wani ɓangare na tsarin magunguna da yawa wanda kuma zai iya haɗawa da masu hana enzyme masu canza angiotensin (masu hana ACE) da diuretics. A ischemic tsokar cuta, beta blockers rage oxygen bukatar na tsokar tsoka da kuma samun antiarrhythmic Properties.

Metoprolol da atenolol suma ana amfani dasu kowane lakabi don wasu alamu. Amfani da lakabin alama yana nufin amfani don nuni wanda ba a yarda da shi ba daga Hukumar Abinci da Magunguna (FDA). Ana amfani dasu galibi don taimakawa hana ƙaura da sarrafa girgizar ƙasa.

Wannan na iya zama ba cikakken jerin amfanin amfani da waɗannan kwayoyi ba ne. Kwararren likitan ku ko likitan ilimin likitancin zuciya ne kawai zasu iya yanke shawara idan ɗayan waɗannan magungunan sun dace da yanayin ku.

Yanayi	Metoprolol	Atenolol
Angina pectoris (ciki har da na yau da kullun, angina mai karko, da kuma rashin kwanciyar hankali)	Ee	Ee
Hawan jini	Ee	Ee
Ajiyar zuciya	Ee	Ba
Ciwon zuciya	Ee	Ee
Gudanar da bugun zuciya a cikin ɓarnawar atrial ko atrial flutter	Kashe-lakabi	Kashe-lakabi
Tsoro	Kashe-lakabi	Kashe-lakabi
Ciwon ƙwayar cuta na Migraine	Kashe-lakabi	Kashe-lakabi
Paroxysmal supraventricular tachycardia prophylaxis	Ba	Kashe-lakabi
Janye barasa	Ba	Kashe-lakabi

Shin metoprolol ko atenolol sun fi tasiri?

Metoprolol da atenolol an yi nazarin su kuma an gwada su sosai don alamomi da sakamako daban-daban. A meta-bincike wanda aka buga a cikin shekara ta 2017 yayi kimanta tasirin kamantawa na waɗannan masu toshe beta tare da propranolol da oxprenolol ta hanyar duban sakamakon gwaji na asibiti da yawa. Metoprolol ya nuna raguwa mai saurin haɗarin mutuwar mace da jijiyoyin jini idan aka kwatanta da atenolol. Metoprolol kuma ya nuna raguwar yanayin ga dalilin-yawan mace-mace da cututtukan zuciya. Lokacin da aka kimanta don rage haɗarin bugun jini, metoprolol ya tabbatar da cewa ya fi atenolol kyau. Akwai bayanai Wannan yana nuna cewa duka kwayoyi suna da tasiri akan placebo kuma babu wani bambanci mai mahimmanci tsakanin atenolol da metoprolol dangane da ikon su na sarrafa karfin jini (hauhawar jini).

Metoprolol an nuna rage yawan karfin jini da na diastolic. Atenolol na iya shafar hawan jini fiye da diastolic, musamman a lokacin aiki.

Dangane da wannan bayanin, likitanku na iya zaɓar farawa tare da metoprolol da farko yayin zaɓar wakili a gare ku. Kwararren likitan ku ne kawai zai iya tantancewa idan maganin toshe beta ya dace da ku.

Verageaukar hoto da kwatancen farashi na metoprolol vs. atenolol

Metoprolol magani ne na takardar sayan magani wanda ya shafi tsarin inshorar kasuwanci da na Medicare. Idan ka biya kuɗi don takardar magani na metoprolol, zaka iya biyan kusan $ 31 don wadatarwar wata guda. SingleCare yana ba da takardar kuɗi wanda zai ba ka damar kusan dala 4 don metoprolol.

Atenolol magani ne na takardar sayan magani wanda ya shafi tsarin inshorar kasuwanci da na Medicare. Ba tare da inshora ba, zaka iya biyan kusan $ 30 don samarwa na kwanaki 30 na 50 MG allunan. Tare da katin ajiya daga SingleCare, zaka iya biyan kusan $ 9 don wannan takardar kuɗin.

	Metoprolol	Atenolol
Yawanci inshora ke rufe shi?	Ee	Ee
Yawanci an rufe shi ta Medicare Part D?	Ee	Ee
Yawan	60, 50 MG Allunan	30, 50 MG allunan
Hanyar biyan kuɗaɗe na Medicare	$ 0- $ 9	$ 0- $ 10
SingleCare kudin	$ 4- $ 22	$ 9- $ 25

Sakamakon illa na yau da kullun na metoprolol vs. atenolol

Masu hana beta masu karɓa kamar metoprolol da atenolol suna rage saurin da zuciya ke bugawa da kuma ƙarfin da yake dokewa. Wannan jinkirin bugun zuciyar na iya haifar da bradycardia, ko ƙananan bugun zuciya. Lokacin da zuciya ba ta bugawa da karfi, wani lokacin kwararar jini ba ta kaiwa ga tsauraran matakai tare da matsin lambar da muke so, wanda ke haifar da tsauraran matakan da kan iya zama sanyi ga tabawa.

Lessarancin jini mai ƙarfi da raguwar jijiyoyin jini na iya haifar da sakamako masu illa kamar su postension postural, wani haske da ke dimaucewa yayin tsayawa bayan kwanciya ko kwance. Hakanan ciwon kai na iya faruwa a marasa lafiya masu shan metoprolol da atenolol.

Wannan ba ana nufin ya zama cikakken jerin abubuwan illa ba. Da fatan za a tuntuɓi likitan magunguna ko likita don cikakken jerin.

	Metoprolol	Atenolol
Sakamakon sakamako	Ana amfani?	Mitar lokaci	Ana amfani?	Mitar lokaci
Gajiya	Ee	Ba a ruwaito ba	Ee	0.6%
Dizziness	Ee	Ba a ruwaito ba	Ee	4%
Bacin rai	Ee	Ba a ruwaito ba	Ee	0.6%
Ciwon kai	Ee	Ba a ruwaito ba	Ba	n / a
Rashin numfashi	Ee	Ba a ruwaito ba	Ee	0.6%
Bradycardia	Ee	Ba a ruwaito ba	Ee	3%
Matsanancin sanyi	Ee	Ba a ruwaito ba	Ba	n / a
Hawan jini	Ee	Ba a ruwaito ba	Ee	kashi biyu
Hanzari	Ee	Ba a ruwaito ba	Ba	n / a
Gudawa	Ee	Ba a ruwaito ba	Ee	kashi biyu
Ciwan	Ee	Ba a ruwaito ba	Ee	4%
Rash	Ee	Ba a ruwaito ba	Ba	n / a

Source: Metoprolol ( DailyMed ) Atenolol ( DailyMed )

Magungunan ƙwayoyi na metoprolol vs. atenolol

Digoxin da masu toshe beta kamar su metoprolol da atenolol kowannensu yana shafar tasirin ƙuntatawa da bugun zuciya. Lokacin da aka ba su tare, marasa lafiya suna cikin haɗarin ƙwayar bradycardia da hauhawar jini. Yakamata yawan bugun zuciya, hawan jini, da sauran alamomin rashin tabin hankali a kai a kai idan ana basu tare.

Metoprolol da Atenolol haɗe tare da masu toshe tashar kalsiyam kamar amlodipine na iya haifar da da ƙarin raguwa a cikin ƙwayar zuciya wanda zai iya zama haɗari. Idan haɗin ya zama dole, yana da mahimmanci a sami ma'aunin aikin yau da kullun kuma a sami ci gaba akai-akai.

Magungunan antidepressants na yau da kullun kamar fluvoxamine, clomipramine, da zaɓaɓɓun maɓuɓɓugan maganin serotonin (SSRIs) sun hana enzyme (CYP2D6) wanda ke da alhakin maganin metoprolol. Lokacin da aka ba su haɗuwa tare da metoprolol, waɗannan kwayoyi na iya haifar da haɓaka cikin matakan metoprolol. Wadannan na iya haifar da ƙarin tasiri ta hanyar metoprolol akan tsarin zuciya.

Wannan ba ana nufin ya zama jerin abubuwan haɗin hulɗa na miyagun ƙwayoyi ba. Ya kamata ku nemi likitan lafiyar ku don cikakken jerin.

Drug	Ajin magani	Metoprolol	Atenolol
Reserpine Clonidine Methyldopa	Alpha adrenergic antagonists	Ee	Ee
Selegiline Phenelzine Isocarboxazid	Monoamine oxidase masu hanawa (MAOIs)	Ee	Ee
Digoxin	Digitalis glycosides / antiarrhythmic	Ee	Ee
Amlodipine Nifedipine Diltiazem Verapamil	Masu toshe tashar calcium	Ee	Ee
Fluvoxamine Clomipramine Tsammani	Magungunan Magunguna	Ee	Ba
Fluoxetine Paroxetine Sertraline	Masu zaɓin maganin serotonin masu zaɓe (SSRIs)	Ee	Ba
Hydralazine	Vasodilator	Ee	Ee
Dipyridamole	Mai hana yaduwar platelet	Ee	Ee
Ergotamine Dihydroergotamine	Ergot alkaloids	Ee	Ee

Gargadi na metoprolol da atenolol

Masu toshewar Beta suna haifar da baƙin ciki na ciwon zuciya. A wasu marasa lafiya tare da wasu dalilai masu haɗari, wannan na iya haifar da gazawar zuciya. Idan wannan ya faru, ya kamata a bi da gazawar zuciya bisa ga jagororin yanzu.

Bai kamata a dakatar da masu hana Beta ba zato ba tsammani, musamman ma a cikin marasa lafiya da ke fama da jijiyoyin jijiyoyin jini. An bayar da rahoton bugun zuciya da cututtukan zuciya na marasa lafiya waɗanda ba da daɗewa ba suka dakatar da masu hana beta.

Idan zai yiwu, ya kamata a guji masu hana beta a cikin marasa lafiya da cututtukan bronchospastic, kamar asma. Yin amfani da shi tare na iya kara cutar cututtukan mashako. Idan ya zama dole a yi amfani da masu toshe beta, an fi son waɗanda suka zaɓi zuciya. Ba a ba da shawarar yin amfani da masu hana beta masu amfani da zuciya ba, kamar su carvedilol.

Ya kamata a rage yin allurar Atenolol a cikin marasa lafiya masu cutar koda ko nakasassu yayin da ake yin jinkirin fitar da maganin.

Tsarin sarrafawa gwajin asibiti wanda The Lancet ya wallafa ya nuna cewa marasa lafiyar da ke yin tiyata yayin da suke kan masu hana beta (musamman metoprolol) suna cikin haɗarin mummunan sakamako kamar ciwon zuciya ko bugun jini. Koyaya, ba abin shawara bane a dakatar da beta-toshe don tiyata idan an kwantar da mai haƙuri akan sa.

Yana da mahimmanci a san cewa zai iya zama da wuya a lura da alamun hypoglycemia a cikin masu fama da ciwon sukari, kamar tachycardia, saboda za a rufe su ta hanyar tasirin beta.

Rashin hankali da tashin hankali wanda metoprolol da atenolol suka haifar na iya ƙara haɗari da haɗarin faduwa, wanda zai iya zama haɗari ko haifar da raunin kai. Ya kamata a kula da tsofaffi waɗanda suka rigaya suke cikin haɗarin faɗuwa.

Likitan ku kawai zai iya yanke shawara idan metoprolol ko maganin atenolol ba su da lafiya a gare ku.

Tambayoyi akai-akai game da metoprolol vs. atenolol

Menene metoprolol?

Metoprolol magani ne na takardar sayan magani wanda aka keɓance azaman mai toshe beta mai karɓar zuciya. Yana aiki don magance hauhawar jini da angina ta hanyar rage bugun zuciya da kuma ƙarfin bugun zuciya. Akwai shi a cikin fitowar nan-da nan na roba, da allunan kara-kwari da kawunansu, maganin allura, da na bakin foda.

Menene atenolol?

Atenolol shine mai toshe beta mai canza zuciya wanda ke samuwa ta hanyar takardar sayan magani kawai. Yana aiki don magance hauhawar jini da angina ta hanyar rage bugun zuciya da kuma ƙarfin bugun zuciya. Akwai shi a cikin nan da nan-fito da allunan baka.

Shin metoprolol da atenolol iri daya ne?

Metoprolol da atenolol kowannensu yana hana beta to, kuma ilimin yadda suke aiki iri ɗaya ne, amma ba daidai suke ba. Metoprolol yana da siffofi biyu da ake da su, ɗaya mai ɗan gajeren aiki da kuma wanda zai daɗe yana aiki, kuma ana iya shan shi sau ɗaya ko sau biyu a kowace rana dangane da yadda aka tsara. Metoprolol shima lipophilic ne, ma'ana yana daɗa narkewa a cikin yanayin mai ƙima (lipid). Saboda wannan dalili, yawanci ana ba da shawarar ɗaukar Metoprolol tare da abinci. Ana amfani da Atenolol sau ɗaya kowace rana kuma yana da ruwa. Atenolol yana narkewa a cikin yanayin yanayin ruwa mai yawa, sabili da haka kawai ana buƙatar ɗaukar shi da gilashin ruwa.

Shin metoprolol ko atenolol sun fi kyau?

Bayanai sun nuna cewa waɗannan kwayoyi guda biyu suna da irin wannan sakamakon a cikin marasa lafiya na hauhawar jini, duk da haka sakamakon cututtukan zuciya da na dogon lokaci, kamar raguwar cuta, na iya zama mafi dacewa da metoprolol.

Shin zan iya amfani da metoprolol ko atenolol yayin da nake da juna biyu?

Metoprolol yana cikin Yanayin Ciki C. Babu wani karatun da ya dace don tabbatar da aminci a cikin ciki. Tuntuɓi likita game da shan Metoprolol yayin da take da ciki ko shayarwa. Atenolol yana cikin Yanayin Ciki D. Yana da ƙaranci kuma bai kamata a sha shi yayin daukar ciki ba. Tuntuɓi likita game da matakan da za a ɗauka yayin tsara ciki ko shayarwa.

Zan iya amfani da metoprolol don atenolol tare da barasa?

Duk da yake babu wata hulda da sinadarai kai tsaye tsakanin barasa da masu hana beta kamar metoprolol da atenolol, shan barasa yana haifar da hawan jininka ya faɗi. Haɗin tasirin kwayoyi da giya na iya sanya ka cikin haɗarin suma ko faɗuwa da cutar da kanka.