Levalbuterol vs. Albuterol: Bambanci, kamance, kuma wanne ne mafi alheri a gare ku
Magunguna vs. AbokiBayanin magunguna & manyan bambance-bambance | Yanayin da aka bi | Inganci | Inshorar inshora da kwatancen farashi | Sakamakon sakamako | Hadin magunguna | Gargadi | Tambayoyi
Levalbuterol da albuterol wasu magunguna ne guda biyu da ake amfani da su wajen maganin cutar sankarau da ke da alaƙa da asma da cututtukan huhu da ke ci gaba (COPD). Asthma cuta ce ta numfashi wacce ke shafar mutane na kowane zamani. Yana da halin numfashi, tari, gajeren numfashi, da kirjin kirji. An kiyasta hakan asma ya shafi kusan mutane miliyan 24 a Amurka, gami da yara miliyan 7.
COPD , wani lokacin ana kiransa emphysema, yana da halaye irin na asma, amma kuma ya hada da samar da danshi mai kauri a cikin hanyar iska. Ba a san ainihin abin da ke haifar da asma ba, amma yawancin marasa lafiya da suka kamu da cutar COPD suna da tarihin shan sigari ko fidda lokaci mai tsawo ga masu huhun huhu.
Bronchospasm yayi bayanin wani tsari wanda yake faruwa a duka asma da kuma COPD inda hanyoyin iska suke kwangila, wanda hakan yasa yake wahalar da iska. Wannan wani lokaci ana kiransa azaman bronchoconstriction. Levalbuterol da albuterol duka suna magance bronchospasm, amma suna aiki daban.
Menene manyan bambance-bambance tsakanin Levalbuterol da Albuterol?
Levalbuterol magani ne na likitanci wanda ke da zaɓi mai kyau, mai saurin aiki beta-2-receptor agonist (SABA). Levalbuterol shine R-enantiomer mafi aiki na cakuda albuterol racemic. Levalbuterol yana motsa masu karɓar beta wanda ke haifar da annashuwa na ƙwanƙwasa da ƙwayar tsoka mai sanyin jiki da kuma hanyar buɗe iska. Levalbuterol yana nan a matsayin inhaler mai ƙaran metered (MDI) yana ba da kashi 45 mcg a kowane aiki. Hakanan akwai shi azaman mafita don amfani dashi a cikin inji mai amfani da nebulizer. Wannan maganin nebulizer yana samuwa a cikin ƙananan 0.31 mg / 3 ml, 0.63 mg / 3 ml, da 1.25 mg / 3ml.
Albuterol magani ne na likitanci wanda kuma zaɓi ne mai matsakaici, mai saurin aiki agonist beta-2-receptor (SABA). Albuterol cakuda ne na jinsin R-enantiomers da S-enantiomers tare da R-enantiomer kasancewar shine isomer mai aiki kuma mai aiki a cikin levalbuterol. Racemic albuterol yana samuwa a cikin allunan baka cikin ƙarfin sakin 2 MG da 4 MG da kuma sakin 4 MG da 8 MG. Hakanan ana samun Albuterol a cikin maganin baka a cikin nauyin 2 mg / 5 ml. Albuterol kuma yana zuwa cikin inhaler mai auna awo wanda yake sadar da 90 mcg a kowane aiki da kuma hanyoyin magance nebulizer da yawa.
| Babban bambanci tsakanin Levalbuterol da Albuterol | ||
|---|---|---|
| Levalbuterol | Albuterol | |
| Ajin magani | Matsakaiciyar zaɓi beta-2-agonist | Matsakaiciyar zaɓi beta-2-agonist |
| Alamar alama / ta kowa | Nau'i da janar akwai | Nau'i da janar akwai |
| Menene sunan alamar? | Xopenex | ProAir, Proventil, Ventolin, Accuneb, Vospire |
| Wani nau'i (s) ne miyagun ƙwayoyi ya shigo? | Inhaler mai ƙosar awo, maganin nebulizer | Inhaler da aka ƙaddara ƙarfinsa, maganin nebulizer, allunan baka, maganin baka |
| Menene daidaitaccen sashi? | 0.63 MG ta hanyar nebulizer ko 45 mcg ta hanyar MDI kowane awa 4-6 | 2.5 MG ta hanyar nebulizer ko 90 mcg ta hanyar MDI kowane awa 4-6 |
| Yaya tsawon maganin al'ada? | Tsayawa, gajere | Lokaci, gajere |
| Wanene yawanci yake amfani da magani? | Yara 'yan shekara 4 zuwa sama, manya | Jarirai, yara, manya |
Yanayin da Levalbuterol da Albuterol suka bi da shi
Levalbuterol da albuterol duka suna aiki ta hanyar motsa masu karɓar beta don haifar da annushuwa na tsoka mai santsi a cikin hanyoyin iska, saboda haka barin hanyoyin iska su buɗe kuma ɗaukar ƙarin iska zuwa huhu tare da ƙaramin juriya.
Dukansu levalbuterol da albuterol duk an yarda dasu ne da FDA wajen kula da cutar ta asma, da saurin wucewar bronchospasms ko shakar iska, da kuma COPD mai alaka da cutar sankara. Yana da mahimmanci a lura cewa babu wani magani da aka yarda dashi azaman prophylaxis, ko rigakafi, don waɗannan alamun. Koyaya, an yarda da amfani da albuterol a cikin prophylaxis na motsa jiki wanda ya haifar da bronchospasm. Yawanci, za a gudanar da albuterol na mintina 15 kafin aikin da ake tsammani don rage yuwuwar cutar sanyin jiki da motsa jiki ya haifar. Levalbuterol wani lokacin ana amfani dashi-lakabin kashe don wannan nuni kuma. Kashe lakabin yana nufin ba a amince da amfani da miyagun ƙwayoyi a cikin wannan nuni ta Hukumar Abinci da Magunguna (FDA).
Shafin da ke gaba ya lissafa sanannun sanannun amfani da waɗannan magungunan. Kwararrun likitocin ku kawai zasu iya tantancewa idan wadannan kwayoyi sun dace da yanayin ku. Game da asma mai tsanani da COPD bronchospasm, da fatan za a nemi magani a cikin sashen gaggawa mafi kusa.
| Yanayi | Levalbuterol | Albuterol |
| Ciwan asma | Ee | Ee |
| Baranchospasm mai saurin wucewa / episodic wheezing | Ee | Ee |
| Motsa jiki-haifar da cutar sankarau | Kashe-lakabi | Ee |
| COPD hade da bronchospasm | Ee | Ee |
| M jiyya na hyperkalemia | Kashe-lakabi | Kashe-lakabi |
| Maganin haɗin kai ga cututtukan numfashi na jarirai | Ba | Kashe-lakabi |
Shin Levalbuterol ko Albuterol sun fi tasiri?
Levalbuterol da albuterol an kwatanta su sosai game da asma da sakamakon COPD. A shekara ta 2015 karatu kimanta manya waɗanda suka kamu da asma ko kuma cututtukan COPD waɗanda aka kula da su ko dai levalbuterol ko albuterol da ake gudanarwa ta hanyar nebulization. Sakamakon wannan gwajin na asibiti ya gano cewa sakamakon asibiti iri daya ne tsakanin magungunan biyu kuma dukansu suna da tasiri wajen sauƙaƙe alamomin cutar sankarau. Koyaya, farashin magani na levalbuterol ya kasance mai tsada sosai fiye da kuɗin maganin albuterol, kuma marasa lafiya a cikin ƙungiyar levalbuterol sun sami kwanciyar hankali sosai fiye da marasa lafiya a cikin ƙungiyar albuterol. Tsawon kwanciya asibiti kuma yana ƙara yawan kuɗin ayyukan.
ZUWA meta-bincike da kuma nazari na yau da kullun na gwaji daban-daban guda bakwai, gami da marasa lafiya sama da 1,600, an yi ta gwada levalbuterol zuwa albuterol a cikin babban asma. Wannan binciken bai sami wani banbanci mai mahimmanci tsakanin magunguna ba yayin gwada sakamakon asibiti kamar ƙarancin numfashi, ƙarancin oxygen, da canji a cikin huhun huhu. Sometimesarar huhu wani lokaci ana kiranta azaman ƙarar ƙarfin tilastawa, ko FEV1, a cikin wallafe-wallafen likita. Wannan binciken ya kammala babu wata hujja da zata goyi bayan zabar levalbuterol akan albuterol wajen kula da asma.
Duk da cewa magungunan biyu suna da tasiri, masu rubutun magunguna na iya yin la'akari da rashin shaidar tabbatar da fifikon levalbuterol da tsada mafi girma yayin yanke shawarar wane magani ne zai rubuta. Levalbuterol kawai an yarda da shi ne a cikin marasa lafiyar yara shekaru huɗu da haihuwa, saboda haka za a fifita albuterol a cikin ƙananan yara na yara. Likitan ku kawai zai iya zaɓar madaidaicin magani don yanayin ku.
Samu takardar takardar sayan magani
Verageaukar hoto da kwatancen farashi na Levalbuterol vs. Albuterol
Levalbuterol magani ne na likita wanda yawancin shirye-shiryen inshorar kasuwanci ke rufe shi. Yana iya rufe shi ta hanyar shirin Medicare Sashe na D ko Sashe na B dangane da asalin cutar. Ba tare da ɗaukar hoto ba, levalbuterol na iya cin kuɗin fiye da $ 170. Takaddun shaida na SingleCare don jigilar Levalbuterol na iya rage farashin zuwa $ 30 a manyan kantunan da ke shiga.
Albuterol na iya rufe shi ta hanyar shirin Medicare Sashe na D ko Sashe na B dangane da ganewar asali. Hakanan yawanci ana rufe shi ta tsare-tsaren inshorar kasuwanci. Albuterol na iya cin kuɗi kamar $ 40 ba tare da ɗaukar hoto ba, amma tare da takaddun shaida daga SingleCare, zaka iya samun nau'in jigilar kuɗi ƙasa da $ 10 a cikin kantin magunguna masu shiga.
| Levalbuterol | Albuterol | |
| Yawanci inshora ya rufe? | Ee | Ee |
| Yawanci an rufe shi ta Medicare Part D? | Dogaro da ganewar asali | Dogaro da ganewar asali |
| Daidaitaccen sashi | 25, 0.63 mg / 3 ml | 25, 2.5 mg / 3 ml |
| Hanyar biyan kuɗaɗe na Medicare | Dogaro da shirin | Dogaro da shirin |
| SingleCare kudin | $ 30- $ 130 | $ 10- $ 20 |
Sakamakon illa na yau da kullun na Levalbuterol vs. Albuterol
Duk da yake levalbuterol da albuterol suna zaɓaɓɓun matsakaita don masu karɓar beta akan ƙwayar tsokar da aka nufa ta hanyoyin iska, har yanzu ana iya samun wasu motsawar beta-receptor na zuciya da ke haifar da ƙaruwar bugun zuciya, wanda aka sani da tachycardia. Dukansu levalbuterol da albuterol na iya haifar da damuwa da rawar jiki. Migraine da dizziness an lura dasu tare da levalbuterol, amma ba albuterol ba.
Wannan ba ana nufin ya zama cikakken jerin tasirin tasiri ba. Da fatan za a tuntuɓi mai ba ku kiwon lafiya don cikakken jerin abubuwan illa.
| Levalbuterol | Albuterol | |||
| Sakamakon sakamako | Ana amfani? | Mitar lokaci | Ana amfani? | Mitar lokaci |
| Tachycardia | Ee | 2.7% | Ee | 2.7% |
| Ciwon mara | Ee | 2.7% | Ba | n / a |
| Dyspepsia | Ee | 2.7% | Ee | 1.4% |
| Matsanancin kafa | Ee | 2.7% | Ee | 1.4% |
| Dizziness | Ee | 2.7% | Ba | n / a |
| Hawan jini | Ba | n / a | Ee | 2.7% |
| Ciwan jiki | Ee | 9.6% | Ee | 8.1% |
| Tsoro | Ee | 6.8% | Ee | 2.7% |
| Tashin hankali | Ee | 2.7% | Ba | n / a |
| Coughara tari | Ee | 4.1% | Ee | 2.7% |
| Kwayar cuta ta kwayar cuta | Ee | 12.3% | Ee | 12.2% |
| Rhinitis | Ee | 2.7% | Ee | 6.8% |
| Sinusitis | Ee | 1.4% | Ee | 2.4% |
| Turbinate edema | Ee | 1.4% | Ba | n / a |
Source: Levalbuterol ( DailyMed ) Albuterol ( DailyMed )
Magungunan ƙwayoyi na Levalbuterol vs. Albuterol
Saboda kamanceceniyar su, tasirin hulɗar miyagun ƙwayoyi don levalbuterol da albuterol suna da kamanceceniya. Azithromycin, maganin rigakafi na yau da kullun wanda ake amfani dashi sau da yawa a cikin cututtukan numfashi na sama, ya kamata a guji haɗuwa tare da levalbuterol ko albuterol idan zai yiwu. Azithromycin, lokacin da ake gudanar da shi tare da beta-agonists mai ɗan gajeren aiki, yana da haɗarin haifar da tsawan QT, wani nau'in cututtukan zuciya na zuciya. Idan dole ne a yi amfani da wannan haɗin, ya kamata a kula da aikin zuciya na mai haƙuri a hankali. Yana da mahimmanci don samun asalin aikin zuciya kafin gudanar da waɗannan magungunan a lokaci guda.
Masu hana Beta, galibi ana amfani dasu don sarrafa bugun zuciya da hawan jini, suna aiki akasin beta-agonists. Ayyukansu zasu magance juna. Idan mai haƙuri dole ne ya kasance mai hana beta da beta-agonist, ta amfani da maƙerin beta mai zaɓin zuciya. Misalan masu toshe beta da keɓaɓɓu sun haɗa da atenolol da metoprolol, da sauransu.
Wannan ba cikakken lissafi bane na hulɗar miyagun ƙwayoyi ba. Da fatan za a nemi shawarar likitan likita don cikakkiyar fahimtar hulɗar miyagun ƙwayoyi.
| Drug | Ajin magani | Levalbuterol | Albuterol |
| Maganin kafeyin | Xanthine wanda ya samo asali / CNS mai kara kuzari | Ee | Ee |
| Phenylephrine Pseudoephedrine | Masu lalata kayan ciki | Ee | Ee |
| Acebutolol Atenolol Betaxolol Bisoprolol Carvedilol Metoprolol Nadolol Nebivolol Propranolol Sotalol | Masu hana Beta (masu adawa da beta) | Ee | Ee |
| Amiodarone Dronedarone | Anti-arrhythmics | Ee | Ee |
| Amitriptyline Clomipramine Nortriptyline | Magungunan antioxidric na Tricyclic | Ee | Ee |
| Citalopram Escitalopram Fluoxetine Sertraline | Zaɓuɓɓukan maganin serotonin reuptake (SSRIs) | Ee | Ee |
| Azithromycin Clarithromycin | Maganin rigakafi | Ee | Ee |
| Fluconazole Itraconazole Ketoconazole | Antifungals | Ee | Ee |
Gargadi na Levalbuterol da Albuterol
Levalbuterol da albuterol na iya haifar da gurguntaccen iska, yanayin da majinyacin mara lafiya ko kumburin ciki yake daɗa muni maimakon ingantawa. Idan wannan ya faru, ya kamata a dakatar da maganin nan da nan kuma ya kamata a fara sabon magani.
Kasancewar asma na iya faruwa na tsawon awanni, kwanaki, ko mafi tsawo. Idan mai cutar asthmatic ya fara buƙatar ƙarin ƙwayoyin cuta don sarrafa cututtukan asma, wannan na iya zama alama cewa rashin daidaito na faruwa. Marasa lafiya da ke fuskantar wannan na iya buƙatar maganin cututtukan kumburi kamar corticosteroids ko canji a cikin tsarin shan magani.
Levalbuterol da albuterol, musamman a allurai sama da adadin da aka ba da shawarar, na iya haifar da mummunan sakamako na zuciya da jijiyoyin jini kamar ƙaruwar bugun zuciya da hawan jini. A wasu lokuta masu tsanani, kamun zuciya ya faru. Kada ku wuce shawarar likita da likitanku ya tsara.
An lura da ƙananan sinadarin potassium, ko hypokalemia, tare da levalbuterol da albuterol. Wannan na iya faruwa ta hanyar ɓarkewar ƙwayoyin cuta. Duk da yake wasu lokuta ana amfani da waɗannan magungunan kashe-lakabin don rage matakan potassium da gangan, ya kamata a kula da wannan tasirin.
Tambayoyi akai-akai game da Levalbuterol vs. Albuterol
Menene Levalbuterol?
Levalbuterol magani ne na likitanci wanda yake ɗan gajeren aiki beta-agonist, wanda aka fi sani da bronchodilator. Ana amfani dashi don magance cutar sankara da ta shafi asma da COPD. Hakanan ana amfani dashi ba tare da lakabi don taimakawa hana haɓakar-motsa jiki. Akwai shi a cikin hanyar inhaler mai awo da kuma magunan da za'a yi amfani dasu a cikin nebulizer.
Menene Albuterol?
Albuterol kuma magani ne na likitanci wanda shine ɗan gajeren aiki beta-agonist. An kuma san shi azaman mai shan iska kuma ana amfani da shi don magance cututtukan da ke da alaƙa da asma da COPD da kuma hana ƙwanƙwasa-motsa jiki. Akwai shi ta hanyoyi daban-daban da suka hada da allunan baka, maganin baka, inhaler masu auna metered, da kuma hanyoyin da za'a yi amfani dasu a cikin nebulizer.
Shin Levalbuterol da Albuterol iri daya ne?
Levalbuterol da albuterol sunada kamanceceniya, amma ba daidai suke ba. Albuterol cakuda ne na jinsin enantiomers guda biyu, R-albuterol da S-albuterol. Wani lokaci ana kiransa azaman tseren albuterol. Levalbuterol ya ƙunshi R-albuterol kawai, mafi ƙarfin mahaɗan biyu.
Shin Levalbuterol ko Albuterol sun fi kyau?
Binciken baya karatu gabaɗaya sun nuna cewa levalbuterol da albuterol suna da sakamako irin na asibiti. Masu tsara rubutu na iya yin la'akari da halaye irin wannan tsadar da tasirin illa yayin zaɓar ɗayan akan ɗayan.
Zan iya amfani da Levalbuterol ko Albuterol yayin da nake da ciki?
Levalbuterol da albuterol duka ana ɗauke da rukunin masu ciki C ta FDA. Wannan yana nufin babu kyawawan karatun asibiti don nuna aminci a cikin ciki. Ya kamata a yi amfani da waɗannan ƙwayoyin ne kawai lokacin da fa'idodi suka fi haɗarin haɗari. A waɗannan yanayin, ana iya fifita albuterol saboda kasancewar ƙarin bayanan tarihi game da amfani da shi a cikin ciki.
Zan iya amfani da Levalbuterol ko Albuterol tare da barasa?
Babu takaddama kai tsaye tare da albuterol da barasa. Koyaya, barasa na iya rage saurin numfashi kuma yana shafar aikin huhu, wanda ba shi da fa'ida ga magance cutar sanyin jiki.
Shin Levalbuterol mai shan iska ne?
Haka ne, levalbuterol HFA shine inhaler mai ceto wanda aka nuna don amfani dashi don kula da cututtukan fuka ko kuma cututtukan bronchospasms saboda COPD.
Shin Levalbuterol wani steroid ne?
Levalbuterol ba shine steroid ko anti-kumburi ba kuma bai kamata ayi amfani dashi maimakon steroid ba lokacin da aka nuna amfani da steroid, kamar a cikin rashin lafiyar asma.
Har yaushe Levalbuterol zai wuce?
A matsakaici, sakamakon kwaya ɗaya na levalbuterol na iya wuce awa biyar zuwa shida. Levalbuterol ya fara aiki kimanin minti 15 bayan gudanarwa.
