Cymbalta vs. Zoloft: Bambanci, kamanceceniya, kuma wanene yafi muku alheri
Magunguna vs. AbokiBayanin magunguna & manyan bambance-bambance | Yanayin da aka bi | Inganci | Inshorar inshora da kwatancen farashi | Sakamakon sakamako | Hadin magunguna | Gargadi | Tambayoyi
Cymbalta da Lexapro sune magunguna guda biyu da ake amfani dasu don magance babbar matsalar damuwa (MDD) da sauran cututtukan kiwon lafiya na tunanin mutum. Bacin rai, damuwa, da rikice-rikice masu alaƙa sun shafi miliyoyin Amurkawa bisa ga Xiungiyar Tashin hankali da Depacin Cutar Amurka .
Rashin lafiyar hauka ya shafi yanayi, yawan aiki, da ikon mutum don magance damuwa. Ga wasu, abubuwa kamar motsa jiki, zuzzurfan tunani, ko magani na iya ba da taimako, amma ga mutane da yawa, za a buƙaci magani don cimma gafarar bayyanar cututtuka. Duk da yake Cymbalta da Lexapro suna magance rikice-rikice iri-iri masu yawa, magunguna daban-daban ne, kuma zamu tattauna waɗannan bambance-bambance a nan.
Menene manyan bambance-bambance tsakanin Cymbalta da Zoloft?
Cymbalta (duloxetine) magani ne na likitanci wanda aka nuna a cikin maganin manyan cututtukan ciki da rikicewar damuwa (GAD). Cymbalta na cikin ƙungiyar magunguna da aka sani da masu zaɓin maganin serotonin-norepinephrine reuptake (SNRIs). Cymbalta yana toshe reuptake na duka norepinephrine da serotonin a cikin synapse na neuronal yana barin ƙarin serotonin da norepinephrine. Waɗannan ƙananan ƙwayoyin jijiyoyin an sami wadatar su don taka rawa mai kyau akan yanayi da tasiri. Sauran SNRIs da zaku iya sani shine Effexor (venlafaxine) da Pristiq (desvenlafaxine). Ana samun Cymbalta azaman 20 mg, 30 mg, da 60 mg na maganin kwalliya.
Zoloft (sertraline) kuma magani ne na likitanci wanda aka nuna a kula da MDD. Zoloft an kasafta shi azaman mai zazzabin serotonin reuptake mai hanawa kuma yana aiki ta hanyar hana reuptake kawai serotonin a cikin neuronal synapse. Matakan da ke akwai na serotonin suna da alaƙa da ingantaccen yanayi da matakan kuzari. Sauran SSRI ɗin da ƙila za ku saba da su sun haɗa da Prozac (fluoxetine), Paxil (paroxetine), Celexa (citalopram), da Lexapro (escitalopram).
Zoloft yana samuwa azaman kwamfutar hannu ta baka cikin ƙarfin 25 MG, 50 MG, da 100mg. Hakanan ana samun shi a cikin maganin maganin bakin wanda yake 20 mg / ml.
| Babban banbanci tsakanin Cymbalta da Zoloft | ||
|---|---|---|
| Cymbalta | Zoloft | |
| Ajin magani | Mai zaɓin maganin serotonin norepinephrine reuptake | Zaɓin maɓallin serotonin reuptake |
| Alamar alama / ta kowa | Nau'i da janar akwai | Nau'i da janar akwai |
| Menene sunan gama-gari? | Duloxetine | Sertraline |
| Wani nau'i (s) ne miyagun ƙwayoyi ya shigo? | Maganin baka | Allunan baka da kuma bayani |
| Menene daidaitaccen sashi? | 60 MG sau ɗaya a rana | 50 MG sau ɗaya a rana |
| Yaya tsawon maganin al'ada? | Tsawon lokaci (watanni zuwa shekaru) | Tsawon lokaci (watanni zuwa shekaru) |
| Wanene yawanci yake amfani da magani? | Matasa da manya | Yara, matasa, da manya |
Yanayin da Cymbalta da Zoloft suka kula da shi
Cymbalta da Zoloft kowannensu an yarda dashi don magance babbar matsalar damuwa, amma kowane magani yana da alamomi na musamman. An yarda da Cymbalta don magance rikicewar rikicewar gaba ɗaya. Hakanan an yarda da Cymbalta don magance ciwon jijiya da ciwo mai ci gaba. Wannan ya sanya Cymbalta baya ga sauran magunguna masu kwantar da hankula saboda shi kaɗai ne aka yarda da shi a cikin binciken da ya shafi ciwo.
Zoloft ya sami amincewar Hukumar Abinci da Magunguna (FDA) don magance rikice-rikicen tashin hankali da rikicewar rikice-rikice (OCD). Ana amfani da shi a kashe-lakabi cikin rikicewar rikicewar rikicewa da rikicewar tashin hankali rabuwa. Amfani da lakabin alama yana nuna cewa FDA ba ta amince da amfanin da aka yi niyya ba.
Wannan teburin nuni don dalilai ne na bayanai kawai kuma baya nufin ya zama shawarar likitanci. Da fatan za a ziyarci likitan lafiyar ku don sanin wane magani ne mafi kyau ga yanayin ku.
| Yanayi | Cymbalta | Zoloft |
| Babban damuwa | Ee | Ee |
| Anxietyarin damuwa | Ee | Kashe-lakabi |
| Jin zafi da ke hade da cutar ciwon sukari neuropathy | Ee | Ba |
| Jin zafi da ke haɗuwa da fibromyalgia | Ee | Ba |
| Jin zafi na musculoskeletal | Ee | Ba |
| Danniya rashin aikin fitsari | Kashe-lakabi | Ba |
| Rikicin tashin hankali | Ba | Ee |
| Rashin hankali-tilasta cuta | Ba | Ee |
| Rabuwa tashin hankali | Ba | Kashe-lakabi |
| Rashin damuwa na posttraumatic | Ba | Ee |
| Rashin tsoro | Ba | Kashe-lakabi |
| Hasken zafi saboda karancin al'ada | Ba | Kashe-lakabi |
| Fitar maniyyi da wuri | Ba | Kashe-lakabi |
Shin Cymbalta ko Zoloft sun fi tasiri?
ZUWA karatu wanda aka buga a cikin 2016 kai tsaye idan aka kwatanta Cymbalta da Zoloft akan ingancin su wajen magance bakin ciki, kuma binciken ya duba takamaiman alamun rashin damuwa. Gabaɗaya, an nuna magungunan biyu suna da tasiri wajen magance baƙin ciki, tare da ɗayan ba shi da kyau fiye da ɗayan gaba ɗaya. Koyaya, yayin duban takamaiman bayyanar cututtuka, kowane magani ya bayyana yana da fa'ida ta musamman tare da alamun bayyanar. Treatedungiyar da aka yi wa maganin Cymbalta ta nuna ƙarin ci gaba game da rashin tabin hankali, ɓacin rai, da lalata jima'i. Zoungiyar Zoloft ta nuna ƙarin ci gaba a cikin bayyanar cututtuka irin su tashin hankali, damuwa, da hypochondriasis. Dukansu Cymbalta da Zoloft suna da tasiri wajen magance ɓacin rai, amma wannan binciken yana nuna masu rubutun ya kamata su ba da hankali na musamman ga alamun bayyanar mutum yayin zaɓar far.
Verageaukar hoto da kwatancen farashi na Cymbalta vs. Zoloft
Cymbalta magani ne na likitanci wanda yawanci tsarin kasuwanci da magunguna ke rufe shi. Farashin kuɗi na aljihu don Cymbalta 60 MG na iya zama sama da $ 300, amma tare da takaddun shaida daga SingleCare, zaku iya samun jigilar kuɗi kamar $ 15 a shagunan sayar da magani.
Zoloft kuma magani ne na likitanci wanda gabaɗaya ke rufe shi ta Medicare da shirye-shiryen magungunan kasuwanci. Farashin kuɗaɗen farashi mai suna Zoloft na iya wuce $ 400, amma zaka iya amfani da coupon daga SingleCare don samun jumlar sigar na $ 10.
Nemi katin rangwame na SingleCare
| Cymbalta | Zoloft | |
| Yawanci inshora ya rufe? | Ee | Ee |
| Yawanci an rufe shi ta Medicare Part D? | Ee | Ee |
| Daidaitaccen sashi | 30, 60 mg capsules | 30, 50 MG allunan |
| Hanyar biyan kuɗaɗe na Medicare | Kasa da $ 10 | Kasa da $ 10 |
| SingleCare kudin | $ 15 + | $ 10 + |
Illolin gama gari na Cymbalta vs. Zoloft
Cymbalta da Zoloft duka sanannu ne don haifar da rikicewar hanji kamar tashin zuciya, gudawa, da maƙarƙashiya. Nausea ita ce mafi tasirin tasiri ga magungunan duka biyu kuma yana iya tasiri ingancin rayuwa. Idan kunji tashin zuciya wanda ke shafar ayyukanku na yau da kullun, ya kamata ku sanar da likitan ku.
Tashin hankali, ko yawan bacci ko bacci, shima ɗayan illolin Cymbalta da Zoloft ne. Marasa lafiya da ke shan Cymbalta na iya fuskantar ciwon kai da haɓaka hawan jini. Cymbalta, kodayake, bai bayyana yana shafar libido ba, yayin da amfani da Zoloft zai iya.
Wannan teburin ba'a nufin shine cikakken jerin abubuwan illa da zai iya faruwa kuma don dalilai ne kawai na bayani. Da fatan za a tuntuɓi masu sana'a na kiwon lafiya don cikakken jerin.
| Cymbalta | Zoloft | |||
| Sakamakon sakamako | Ana amfani? | Mitar lokaci | Ana amfani? | Mitar lokaci |
| Ciwan | Ee | 2. 3% | Ee | 26% |
| Bakin bushe | Ee | 13% | Ee | 14% |
| Gumi | Ee | 6% | Ee | 7% |
| Gudawa | Ee | 9% | Ee | 4% |
| Maƙarƙashiya | Ee | 9% | Ee | 6% |
| Dyspepsia | Ba | n / a | Ee | 8% |
| Dizziness | Ee | 9% | Ee | 12% |
| Bacci | Ee | 10% | Ee | goma sha ɗaya% |
| Ciwon kai | Ee | 14% | Ba | n / a |
| Pressureara karfin jini | Ee | kashi biyu | Ba | n / a |
| Rage yawan ci | Ee | 7% | Ee | 3% |
| Rage libido | Ba | n / a | Ee | 6% |
Source: Cymbalta ( DailyMed ) Tsalle DailyMed )
Magungunan ƙwayoyi na Cymbalta vs. Zoloft
Cymbalta da Zoloft suna raba wasu hulɗar magungunan ƙwayoyi na yau da kullun, amma akwai wasu waɗanda ke takamaiman kowane magani kuma. Cymbalta ya hana CYP2D6, enzyme da ke da alhakin maganin kwayoyi da yawa ciki har da magungunan da ke da alaƙa da amphetamine. Ana amfani da Amphetamines wajen magance rikicewar raunin hankali, wanda na iya faruwa ga marasa lafiya masu fama da baƙin ciki ko damuwa. Cymbalta na hana wannan enzyme na iya haifar da ƙara matakan jini na amphetamines. Marasa lafiyar da ke kan nau'ikan magungunan biyu ya kamata a sanya musu ido sosai.
Cymbalta da Zoloft suna da damar haifar da cututtukan serotonin yayin haɗuwa da wasu kwayoyi tare da ayyukan serotonergic. Ciwon Serotonin shine sakamakon ƙananan matakan serotonin kyauta kuma yana iya haifar da tashin hankali, jiri, da ƙara ƙarfin zuciya. Magunguna kamar su maganin ƙaura na ƙaura ko kari St. John's Wort na iya haifar da wannan hulɗar.
Zoloft na iya haifar da takamaiman nau'in cututtukan zuciya da aka sani da tazarar tazarar lokacin QTc lokacin da aka ɗauke ta da wasu nau'o'in magunguna. Yana da mahimmanci cewa ƙwararrun likitan ku da likitan magunguna suna da cikakken jerin magungunan da kuke ɗauka domin yin allon dacewa don hulɗar ku.
Jerin mai zuwa ba shine nufin cikakken jerin hulɗar miyagun ƙwayoyi ba. Likitan ku ko likitan magunguna na iya ba da cikakken jerin.
| Drug | Ajin magani | Cymbalta | Lexapro |
| Almotriptan Eletriptan Oxitriptan | 5HT Agonist / Triptans (wakilan antimigraine) | Ee | Ee |
| Gishirin Amphetamine Dexmethylphenidate Methylphenidate | Amfetamines | Ee | Ee |
| Rariya Ondansetron Ramosetron | 5HT3 Masu adawa (wakilan anti-tashin zuciya) | Ba | Ee |
| Aripiprazole | Antipsychotic | Ee | Ee |
| Asfirin Ibuprofen Naproxen Diclofenac | Magungunan anti-inflammatory marasa ƙwayar cuta (NSAIDs) | Ee | Ee |
| Enoxaparin Heparin | Anticoagulants | Ba | Ee |
| Buspirone | Jin tsoro | Ee | Ee |
| Carbamazepine | Mai cin nasara | Ba | Ee |
| Esomeprazole Omeprazole | Proton famfo mai hanawa | Ba | Ee |
| Fluconazole | Antifungal | Ba | Ee |
| Fluoxetine Citalopram Paroxetine Escitalopram | SSRIs | Ee | Ee |
| Hydroxychloroquine | Aminoquinolone / Cutar malariya | Ba | Ee |
| Linezolid | Maganin rigakafi | Ee | Ee |
| Metaxalone | Masu shakatawa na tsoka | Ee | Ee |
| Pimozide | Antipsychotic | Ba | Ee |
| Selegiline Phenelzine Rasagiline | Monoamine oxidase mai hanawa (MAOI) | Ee | Ee |
| St. John’s Wort | Karin ganye | Ee | Ee |
| Hydrochlorothiazide Chlorthalidone Metolazone | Kwayar cutar Thiazide | Ba | Ee |
| Tramadol | Mai cire zafi mai zafi | Ee | Ee |
| Amitriptyline Clomipramine Doxepin Nortriptyline | Magungunan antioxidric na Tricyclic | Ee | Ee |
Gargadi na Cymbalta da Zoloft
Yana da mahimmanci a fahimci cewa Cymbalta ko Zoloft ba za su haifar da gafara nan da nan na alamun ko dai cuta na baƙin ciki ko rashin damuwa. Zai ɗauki mafi ƙarancin makonni biyu don lura da kowane canji a cikin yawancin marasa lafiya, kuma har zuwa makonni huɗu zuwa shida don sanin cikakken tasirin maganin. Kada ka daina shan magani ba tare da bata lokaci ba tare da imanin cewa ba ya aiki ba tare da fara magana da likitanka ba.
Marasa lafiya tare da MDD na iya fuskantar mummunan ɓacin rai ko tunanin kisan kai ko suna shan magungunan rage damuwa. Waɗannan yanayin na iya tsananta har sai an sami gafara. Cymbalta da maganin Zoloft na iya haɓaka ra'ayin kashe kai da tunani tsakanin matasa da matasa, musamman ma a farkon matakan jiyya. Wajibi ne a lura da waɗannan marasa lafiya sosai idan wannan magani yana da mahimmanci a matsayin likita. Canjin canjin yanayi na iya zama dole idan bayyanar cututtuka ba zato ba tsammani ta tashi ko ta ƙara muni.
Akwai rahotanni game da gazawar hanta, wani lokacin na mutuwa, tare da Cymbalta. Wadannan sharuɗɗan na iya gabatarwa tare da ciwon ciki da haɓaka enzymes hanta tare da ko ba tare da jaundice ba. Yin amfani da giya na iya ƙara wannan haɗarin, sabili da haka ya kamata a guji wannan haɗuwa.
Zoloft na iya haifar da takamaiman nau'in cututtukan zuciya da aka sani da tazarar tazarar lokacin QTc lokacin da aka ɗauke ta da wasu nau'o'in magunguna. Yana da mahimmanci cewa ƙwararrun likitan ku da likitan magunguna suna da cikakken jerin magungunan da kuke ɗauka domin yin allon dacewa don hulɗar ku. Da fatan za a nemi shawarar likita daga likitan ku kafin fara sabbin hanyoyin kwantar da hankali.
Ciwon Serotonin an ruwaito shi tare da duk SSRIs da SNRIs, gami da Cymbalta da Zoloft. Wannan yanayin ne da ke da alaƙa da ƙananan matakan serotonin kuma yana iya haifar da haƙuri jin daɗi, damuwa, da samun ƙarar zuciya.
Tambayoyi akai-akai game da Cymbalta vs. Zoloft
Menene Cymbalta?
Cymbalta (menene Cymbalta?) Magani ne na maganin ƙwaƙwalwar ƙwaƙwalwa wanda aka yi amfani dashi don magance babban damuwa, rikicewar damuwa ta gaba ɗaya, da cututtukan cututtukan neuropathic da musculoskeletal. Cymbalta yana cikin aji na magungunan da aka sani da masu zaɓin maganin serotonin-norepinephrine reuptake (SNRIs). Ana samun Cymbalta azaman maganin kwalliya a cikin 20 MG, 30 MG, da ƙarfin 60 MG.
Menene Zoloft?
Zoloft (menene Zoloft?) Magungunan rigakafin magani ne wanda aka yi amfani dashi don kula da babban cututtukan ciki da sauran damuwa da tabin hankali. Zoloft yana cikin aji na magungunan da aka sani da masu zaɓin maganin serotonin reuptake (SSRIs). Akwai Zoloft a matsayin allunan baka a cikin 25 MG, 50 MG, da ƙarfin 100 MG, da kuma mai da ruwa mai ɗaci.
Shin Cymbalta da Zoloft iri daya ne?
Duk da yake Cymbalta da Zoloft suna magance baƙin ciki da cututtukan tabin hankali iri-iri, ba irin maganin ba ne. Cymbalta yana cikin rukunin magungunan da aka sani da masu zaɓin maganin serotonin-norepinephrine reuptake (SNRIs), kuma yana haifar da ƙaruwa a cikin duka serotonin da norepinephrine. Zoloft yana cikin aji na ƙwayoyi waɗanda aka sani da masu zaɓin maganin serotonin reuptake (SSRIs) kuma yana haifar da ƙaruwa cikin wadataccen serotonin.
Shin Cymbalta ko Zoloft sun fi kyau?
Cymbalta da Zoloft suna kamantawa cikin ikon su na magance bakin ciki. Cymbalta yana ɗauke da ƙarin alamomi don damuwa gabaɗaya. Yana da mahimmanci a kalli takamaiman alamun cututtukan ciki da kuma tasirin illa yayin yanke shawarar wane magani ne mafi kyau ga wani mai haƙuri.
Shin zan iya amfani da Cymbalta ko Zoloft yayin da nake da juna biyu?
FDA ta ɗauki duka Cymbalta da Lexapro (menene Lexapro) rukunin ciki C, ma'ana babu wadataccen karatun ɗan adam don ƙayyade lafiya. Tare da Cymbalta, an lura da cututtukan da ba na teratogenic ba a cikin jarirai sabbin yara biyo bayan gwamnatin Cymbalta yayin da take da juna biyu. Wadannan sun hada da matsalar numfashi, matsalar wahala, da rawar jiki. Gabaɗaya, ko dai ya kamata a yi amfani da ƙwayoyi kawai tare da fa'ida ga uwa a fili fiye da haɗarin ɗan tayin.
Zan iya amfani da Cymbalta ko Zoloft tare da barasa?
Marasa lafiya ya kamata su guje wa yawan shan barasa idan shan Cymbalta ko Zoloft. Barasa na iya ƙara tasirin cutar mai guba na magunguna biyu kuma yana iya haifar da lahani ga psychomotor. Tare da Cymbalta musamman, barasa yana ƙara yawan lalacewar hanta.
Menene mafi kyawun antidepressant tare da mafi ƙarancin sakamako?
Magungunan kwantar da hankali a kasuwa a Amurka sun kasance ta hanyar gwaji sosai don tabbatar da suna da tasiri wajen magance baƙin ciki. Kowannensu yana da tasirin illa wanda ke faruwa tare da yaduwa daban-daban. Likitanku zaiyi la'akari da takamaiman alamun cututtukanku da kuma illolin da suka fi damun ku yayin zaɓar magani.
Shin Zoloft yana shafar ku ta hanyar jima'i?
Maƙerin ya ba da rahoton cewa kamar 6% na marasa lafiya na iya fuskantar rage libido, ko rage sha'awar jima'i, yayin shan Cymbalta. Marasa lafiya da suka sami wannan ya kamata suyi magana da ƙwararrun likitocin su game da hanyoyin da zasu iya maye gurbin su.
Wanne ne mafi kyau: Prozac ko Zoloft?
Akwai bayanai don bayar da shawarar cewa Zoloft na iya zama mafi girma ga Prozac (menene Prozac) dangane da inganci yayin magance ɓacin rai. Koyaya, masu rubuta rubutu zasuyi la'akari da dalilai da yawa yayin zaɓar magani. Likitan ku kawai zai iya yanke shawara wanda zai iya zama mafi dacewa a gare ku.
