Nucynta vs. oxycodone: Bambanci, kamance, kuma wanne ne mafi alheri a gare ku
Magunguna vs. AbokiBayanin magunguna & manyan bambance-bambance | Yanayin da aka bi | Inganci | Inshorar inshora da kwatancen farashi | Sakamakon sakamako | Hadin magunguna | Gargadi | Tambayoyi
Nucynta da oxycodone sune yarda biyu na FDA opioid magungunan ƙwayoyi da aka nuna don maganin ciwo mai tsanani, mai zafi. Ana amfani da su gaba ɗaya don ciwo wanda ba za a iya sauƙaƙe ta magungunan marasa opioid ba, ko lokacin da mai haƙuri ba zai iya jure wa sauran hanyoyin ba. Dukkanin magungunan ciwo an rarraba su azaman narcotics ( Jadawalin II ), ma'ana suna da babbar dama ta zagi ko dogaro.
Hanyar Nucynta ba ta fahimta kwata-kwata. Wasu nazarin sun nuna cewa Nucynta shine mai karɓar mu (mai karɓar raɗaɗi) agonist kuma mai hana norepinephrine reuptake inhibitor, wanda ke haifar da sauƙin ciwo. Oxycodone yana aiki ta hanyar ɗaure ga masu karɓar mu a cikin kwakwalwa, wanda ke raunana ko toshe alamun sigina, wanda ke haifar da sauƙin ciwo.
Saboda magungunan biyu suna da ƙarfi, ana amfani dasu gaba ɗaya a cikin yanayin magance ciwo inda mai sauƙin ciwo (mara narcotic) ba zai yi tasiri ba ko ba za a iya jure shi ba. Kodayake ana amfani da magungunan biyu don ciwo mai tsanani, suna da bambance-bambance da yawa, waɗanda za mu zana a ƙasa.
Menene manyan bambance-bambance tsakanin ucNucynta da oxycodone?
Nucynta (tapentadol) opioid ne, ko narcotic, analgesic (mai kashe ciwo). Akwai shi a cikin iri-suna kamar duka biyun sake-fitarwa da ƙara-fitarwa kwamfutar hannu. Ana kiran babban kwamfutar da ake kira Nucynta ER. Halin farko shine 50 MG zuwa 100 MG kowane hudu zuwa shida kamar yadda ake buƙata don ciwo. Likita zai iya gyara wannan maganin, kuma matsakaicin adadin shine 600 MG kowace rana.
Oxycodone shima kwayar cutar opioid analgesic ce (da oxycodone IR, don sakin kai tsaye) kuma ana samunta a cikin nau'ikan suna kamar Oxycontin-an kara fadada kwamfutar hannu. Sashin ya bambanta, amma yawanci na yau da kullun don sakin allunan oxycodone shine 5 zuwa 15 MG kowane awa hudu zuwa shida kamar yadda ake buƙata don ciwo.
| Babban bambanci tsakanin Nucynta da oxycodone | ||
|---|---|---|
| Nucynta | Oxycodone | |
| Ajin magani | Opioid (narcotic) maganin ciwo | Opioid (narcotic) maganin ciwo |
| Alamar alama / ta kowa | Alamar | Brand da janar |
| Menene sunan asali / alama? | Gabaɗaya: Tapentadol | Alamar: OxyIR (fitowar kai tsaye), Oxycontin (mai dogon aiki) |
| Wani nau'i (s) ne miyagun ƙwayoyi ya shigo? | Nan da nan-sake kwamfutar hannu Fadada-saki kwamfutar hannu | Nan da nan-sake kwamfutar hannu Nan da nan-sakin kwantena Fadada-saki kwamfutar hannu Maganin baka |
| Menene daidaitaccen sashi? | Na farko: 50 MG zuwa 100 MG kowane 4 zuwa 6 hours kamar yadda ake bukata. Dose na iya gyara likita kamar yadda ake buƙata. Matsakaicin 700 MG kowace rana a ranar farko ta jiyya, to matsakaicin magani shine 600 MG kowace rana bayan rana ta farko | Nan da nan-sake kwamfutar hannu: 5 zuwa 15 MG kowane 4 zuwa 6 hours kamar yadda ake bukata Fadada-saki kwamfutar hannu: 20 MG kowane 12 hours |
| Yaya tsawon maganin al'ada? | Shortan gajere, ana iya amfani dashi tsawon lokaci bisa yanayin da aka bi (kamar ciwo mai ɗorewa) da martani | Shortan gajere, ana iya amfani dashi tsawon lokaci bisa yanayin da aka bi (kamar ciwo mai ɗorewa) da martani |
| Wanene yawanci yake amfani da magani? | Manya | Manya |
Kuna son mafi kyawun farashi akan Nucynta?
Yi rajista don faɗakarwar farashin Nucynta kuma gano lokacin da farashin ya canza!
Sami faɗakarwar farashi
Yanayin da treatedNucynta da oxycodone suka bi da su
Dukansu Nucynta da oxycodone suna da nuni guda daya don magani, wanda shine sarrafa babban ciwo a cikin manya wanda ya isa ya buƙaci maganin cutar opioid, kuma lokacin da sauran maganin basu isa ba ko kuma basu jurewa ba.
| Yanayi | Nucynta | Oxycodone |
| Gudanar da ciwo mai zafi a cikin manya wanda ya isa mai ƙarfi don buƙatar maganin opioid, kuma lokacin da sauran jiyya basu isa ba | Ee | Ee |
Shin ucNucynta ko oxycodone yafi tasiri?
A cikin wani karatu kwatancen sakin-gaggawa Nucynta zuwa gaggawa-sakin oxycodone a cikin marasa lafiya masu fama da matsanancin ciwo mai tsanani, duka magungunan guda biyu an same su da lafiya da kuma tasiri wajen magance ciwon baya, da kuma ciwon kafa mai haɗewa. Marasa lafiya na Nucynta suna da raunin illa masu alaƙa da ciki.
A cikin wani karatu kwatanta yiwuwar cin zarafin marasa lafiya da ke ɗaukar Nucynta ko oxycodone, an gano Nucynta yana da ƙarancin damar cin zarafi.
Magani mafi inganci a gare ku ya kamata likitan ku kawai ya ƙaddara ku wanda zai duba yanayin lafiyar ku (s), tarihin ku, da sauran magungunan da kuka sha.
Verageaukar hoto da kwatancen farashi na ucNucynta vs. oxycodone
Saboda dokokin jiha, idan kuna karɓar maganin kashe zafin opioid a karon farko, akwai yiwuwar za ku karɓi ƙaramin adadi.
Asusun inshora ya bambanta da Nucynta. Tunda ya fi tsada kuma kawai ana samunta a cikin sunan suna, kuɗin kuɗin ku na iya zama mafi girma, ko kuma magani na iya buƙatar a kafin izini daga kamfanin inshorar ku. Nucynta gabaɗaya baya rufe Medicare Part D. Farashin aljihu don Nucynta 50 MG, 30 allunan yawanci kusan $ 250 amma zaka iya samun shi ƙasa da $ 211 tare da rangwame na SingleCare.
Oxycodone yawanci ana rufe shi ta inshora da kuma Medicare Part D. Farashin kuɗi na aljihu don 30, 5 MG allunan na iya kai kimanin $ 100 amma zaka iya amfani da coupon guda ɗaya a shagunan sayar da magunguna kuma ka sami farawa daga $ 36.
| Nucynta | Oxycodone | |
| Yawanci inshora ya rufe? | Ya bambanta | Ee |
| Yawanci an rufe shi ta Medicare Part D? | Ba | Ee |
| Daidaitaccen sashi | 50 mg, # 30 alluna | 5 mg, # 30 allunan |
| Hankula Medicare Part D copay | $ 95- $ 482 | $ 2 - $ 56 |
| SingleCare kudin | $ 211 + | $ 36- $ 62 |
Sakamakon illa na yau da kullun na ucNucynta vs. oxycodone
Illolin dake tattare da Nucynta sune yawan tashin zuciya, amai, bacci, jiri, rashin ruwa, bushewar baki, da kuma kaikayi. Tashin hankali na numfashi (jinkirin numfashi, rashin samun isashshen oxygen), wanda zai iya zama barazanar rai ko mutuwa, na iya faruwa.
Tare da oxycodone, ba a ba da rahoton ƙididdigar ƙididdiga daidai ba, sai dai cewa tasirin illa ya faru a cikin mafi girma ko daidai da 3% na marasa lafiya. Illolin da suka fi yaduwa sune tashin zuciya, maƙarƙashiya, amai, ciwon kai, pruritus (itching), rashin bacci, jiri, raunin jiki, da bacci. M mummunan halayen na iya haɗawa da baƙin ciki na numfashi, kamawar numfashi (dakatar da numfashi), kamawar zuciya (ɓacewar aikin zuciya kwatsam, numfashi, da sani), ƙarancin jini, da / ko girgiza.
Saboda tsananin haɗari, yana da matukar mahimmanci idan ka ɗauki Nucynta ko oxycodone, ka sha magani daidai yadda aka tsara kuma kar ka ɗauki ƙarin allurai. Hakanan ya kamata a sanya muku ido don ɓacin rai na numfashi, musamman lokacin fara ɗayan waɗannan ƙwayoyi ko yayin canji a cikin kashi.
Sauran abubuwa marasa kyau na iya faruwa. Tuntuɓi mai ba da kiwon lafiya don cikakken jerin abubuwan illa.
| Nucynta | Oxycodone | |||
| Tasirin Side | Ana amfani? | Mitar lokaci | Ana amfani? | Mitar lokaci |
| Ciwan | Ee | 30% | Ee | ≥3% |
| Amai | Ee | 18% | Ee | ≥3% |
| Maƙarƙashiya | Ee | 8% | Ee | ≥3% |
| Bakin bushe | Ee | 4% | Ee | % ba a ruwaito ba |
| Bacci | Ee | goma sha biyar% | Ee | ≥3% |
| Dizziness | Ee | 24% | Ee | ≥3% |
| Itching | Ee | 5% | Ee | ≥3% |
Source: DailyMed ( Nucynta ,, DailyMed ( oxycodone )
Hadin magunguna na ucNucynta vs. oxycodone
Amfani da benzodiazepines ko wasu masu damuwa na CNS, gami da wasu magungunan opioid , a hade tare da Nucynta ko oxycodone na iya haifar da hauhawar jini, bakin ciki na numfashi, zurfin nutsuwa, rashin lafiya, da / ko mutuwa. Ya kamata a guji haɗuwa. Duk da haka, idan babu wani zaɓi, akwai mafi ƙarancin allurai na kowane magani don mafi kankanin lokacin da ya kamata a yi amfani da shi, kuma ya kamata a sa ido sosai a kan mai haƙuri, musamman a farkon jiyya da kuma lokacin kowane canje-canje cikin ƙoshin magani.
Shan Nucynta ko oxycodone tare da kwayoyi masu ƙara serotonin na iya ƙara haɗarin cututtukan serotonin , Yanayin barazanar rai wanda ya haifar da tarin kwayar serotonin da yawa. Wadannan kwayoyi sun hada da masu maganin kara kuzari kamar su serotonin reuptake inhibitors, masu shakatawa na tsoka, masu hana MAO (bai kamata a yi amfani da masu hana MAO a cikin kwanaki 14 na Nucynta ko oxycodone), da kuma maraba da tafiye-tafiye na ƙaura.
Shan oxycodone tare da wasu magunguna waɗanda ake amfani da su ta enzyme da ake kira CYP3A4 ko CYP2D6 na iya haifar da hulɗar magunguna. Wadannan kwayoyi an san su azaman masu hana enzyme kuma sun hada da maganin rigakafin macrolide, azole antifungals, da masu hana kariya. Amfani da su tare da oxycodone na iya haifar da babban matakin opioid, wanda ke da haɗari sosai. Wadannan kwayoyi suna hulɗa tare da oxycodone, amma ba Nucynta ba.
Sauran kwayoyi, waɗanda aka sani da masu haifar da enzyme, suna da akasin hakan azaman masu hanawa, suna rage matakin opioid ta yadda ba shi da tasiri ko ma yana iya haifar da alamun cirewa. Masu ciki suna iya shafar Nucynta ko oxycodone.
Tuntuɓi mai ba da lafiyar ku don cikakken jerin ma'amala da ƙwayoyi.
| Drug | Ajin Magunguna | Nucynta | Oxycodone |
| Alprazolam Clonazepam Diazepam Lorazepam | Benzodiazepines | Ee | Ee |
| Barasa | Barasa | Ee | Ee |
| Codein Fentanyl Hydrocodone Wayar lantarki Methadone Morphine Tramadol | Opioids | Ee | Ee |
| Baclofen Carisoprodol Cyclobenzaprine Metaxalone Tizanidine | Relaxarfafa tsoka | Ee | Ee |
| Amitriptyline Citalopram Tsammani Desvenlafaxine Duloxetine Escitalopram Fluoxetine | Magungunan Magunguna | Ee | Ee |
| Phenelzine Rasagiline Selegiline Tranylcypromine | MAO masu hanawa | Ee | Ee |
| Furosemide Hydrochlorothiazide | Diuretics | Ee | Ee |
| Benztropine Diphenhydramine Oxybutynin Tolterodine | Magungunan Anticholinergic | Ee | Ee |
| Almotriptan Eletriptan Rizatriptan Sumatriptan Zolmitriptan | Masu fassara don ƙaura | Ee | Ee |
| Clarithromycin Erythromycin Fluconazole Ketoconazole Ritonavir | CYP3A4 ko CYP2D6 masu hanawa | Ba | Ee |
| Carbamazepine Phenytoin | CYP3A4 masu ba da ciki | Ee | Ee |
Gargaɗi na ucNucynta da oxycodone
Akwai gargadi mai ban tsoro akan duka Nucynta da oxycodone, wanda shine babban gargaɗin da FDA (Foodasar Abinci da Magunguna ta Amurka ta buƙata).
- Magungunan Opioid suna da haɗarin jaraba, zagi, da rashin amfani. Wannan na iya haifar da yawan maye da kuma mutuwa. Ya kamata a tantance marasa lafiya don haɗari kafin ɗaukar opioid kuma ya kamata a kula da hankali.
- Opioids na iya haifar da mai tsanani, mai barazanar rai, ko ɓacin rai na numfashi. Dole ne a kula da marasa lafiya a hankali, musamman lokacin da aka fara jiyya, da kuma bayan canjin kashi.
- Haɗarin haɗari, musamman ga yara, na iya haifar da yawan wuce gona da iri. Marasa lafiya yakamata su amintar da opioids daga isar yara, kuma suna kullewa da maɓalli idan ya yiwu.
- Yin amfani da opioid mai tsayi yayin daukar ciki na iya haifar da cututtukan cirewar opioid, wanda zai iya zama barazanar rai idan ba a gane shi ba kuma ba a kula da shi ba.
- Yin amfani da benzodiazepines kamar Xanax, ko wasu masu ɓata rai na CNS, kamar sauran opioids (ko giya), na iya haifar da zurfin zugi, ɓacin rai, numfashi, da mutuwa. Haɗin haɗin opioids da benzodiazepines ya kamata a guji idan zai yiwu. Marasa lafiya waɗanda dole ne su ɗauki wannan haɗuwa saboda wasu hanyoyin da ba su aiki ba ya kamata a sanya su mafi ƙarancin tasiri na mafi kankanin lokaci kuma dole ne a sanya musu ido sosai.
Sauran gargadi:
- Marasa lafiya da ke fama da baƙin ciki na numfashi, asma mai tsanani / mai tsanani a cikin yanayin da ba a kula da shi ba, toshewar hanji, ko damuwa ga kowane ɗayan sinadaran kada suyi amfani da Nucynta ko oxycodone.
- Bai kamata a yi amfani da lalata ko kwalliya a cikin marasa lafiya da ke fama da cutar huhu ko tsofaffi ko marasa lafiya masu rauni ba.
- Ciwo na serotonin na iya faruwa, musamman tare da amfani da ƙwayoyi waɗanda ke ƙaruwa matakan serotonin, kamar su magungunan kashe ciki. Ya kamata a kula da marasa lafiya don canjin yanayin tunani (tashin hankali, kallon zuciya), canje-canje a hawan jini, rashin daidaituwa, da / ko alamun ciki kamar tashin zuciya, amai, ko gudawa. Mai haƙuri ya kamata ya nemi likita nan da nan idan ɗayan waɗannan alamun sun faru saboda cutar serotonin tana da haɗari sosai kuma yana iya zama m.
- Rashin ƙarancin adrenal na iya faruwa, yawanci bayan wata ɗaya. Marasa lafiya ya kamata su nemi magani idan sun sami tashin zuciya, amai, rashin cin abinci, gajiya, rauni, jiri, da / ko saukar karfin jini.
- Nucynta ko oxycodone na iya haifar da ƙaran jini.
- Bai kamata a yi amfani da lalata ko kwalliya a cikin marasa lafiya ba tare da hankali ba ko a cikin suma.
- Nucynta ko oxycodone na iya ƙara haɗarin kamuwa da marasa lafiya da cuta mai kamawa.
- Nucynta ko oxycodone bai kamata a janye shi kwatsam ba, amma a maimakon haka sai a sakata a hankali.
- Bai kamata ayi amfani da Nucynta a marasa lafiya masu fama da matsanancin hanta ko koda ba.
- Kada ku fitar da mota ko aiki har sai kun san yadda magungunan ke shafar ku.
- Opioids marasa tsaro na iya zama mummunan haɗari ga kowa a cikin gida, gami da baƙi. Ajiye amintattu, daga gani da isa ga yara, kuma a cikin wurin da ba wasu ba. Tambayi kwararren likitan ku yadda za a zubar da kwayoyin opioids a yankin ku.
- Lokacin shan kowane opioid, yi magana da likitanka game da takardar sayan magani don naloxone, magani wanda zai iya magance yawan ƙwayar opioid a cikin yanayin gaggawa.
Saboda babu karatu mai kyau a cikin mata, Kada a yi amfani da Nucynta ko oxycodone a cikin ciki. Yin amfani da opioids a lokacin daukar ciki, walau na likita ko marasa magani, na iya haifar da dogaro da jiki a cikin jariri, kuma zai iya haifar da cututtukan cirewar opioid ba tare da haihuwa ba jim kadan bayan haihuwa.
Tambayoyi akai-akai game da ucNucynta vs. oxycodone
Menene Nucynta?
Nucynta maganin narcotic ne, ko opioid, mai kashe zafin ciwo da aka yi amfani dashi don maganin ciwo mai tsanani. Akwai shi a cikin suna mai alama azaman sakewa kai tsaye (Nucynta) ko ƙaramar fitowar kwamfutar hannu (Nucynta ER).
Menene oxycodone?
Oxycodone magani ne mai kashe ƙwayoyi wanda ake amfani dashi don magance ciwo mai tsanani. Akwai shi a jumla azaman kwamfutar hannu-kwalliya-kwalliya-kwalliya ko kwantena kuma a cikin suna-mai suna Oxycontin mai dogon aiki.
Shin ucNucynta da oxycodone iri daya ne?
A'a, amma suna kama da juna. Nucynta ya ƙunshi tapentadol. Oxycodone da tapentadol duka magungunan opioid ne (masu ba da ciwo) amma suna da wasu bambance-bambance, kamar su kashi, farashi, da kuma sakamako masu illa, waɗanda aka zayyana a sama.
Shin ucNucynta ko oxycodone shine mafi kyau?
A cikin wani nazarin kwatanta magungunan biyu , Nucynta da oxycodone sun kasance daidai da aminci kuma suna da tasiri wajen magance ƙananan ciwon baya. Nucynta na iya samun ƙananan cin zarafi . Yi magana da likitanka idan Nucynta ko oxycodone sun dace da kai, idan wasu masu ba da taimako na jin zafi ba su taimaka ba ko kuma idan ba za ku iya jure masu ba.
Shin zan iya amfani da Nucynta ko oxycodone yayin da nake ciki?
A'a. Nucynta ko oxycodone (ko kowane opioid, kamar su Percocet) na iya haifar neonatal abstinence janyewar ciwo , wanda zai iya zama haɗari ko barazanar rai ga jariri.
Zan iya amfani da Nucynta ko oxycodone tare da barasa?
A'a. Naukar Nucynta ko oxycodone tare barasa na iya ƙara haɗarin mummunar illa kamar rashin ƙarfin numfashi (rashin samun isashshen iskar oxygen, kuma numfashinka na yin jinkiri) har ma yana iya haifar da suma ko mutuwa.
Me ya fi Nucynta karfi?
Mafi yawan kwayoyin opioids suna da alaƙa da haɗarin wuce gona da iri da mutuwa, a cewar CDC . Yana da mahimmanci a kalli jimillar maganin yau da kullun zuwa MME (nau'ikan miligram na morphine) don yin lissafin haɗarin wuce gona da iri da kuma buƙatar sa ido sosai. Idan kashi na Nucynta baya aiki a gare ku, yi magana da likitan ku game da canza maganin ko canza magani. Kada ku ƙara sashi akan kanku, ba tare da yin magana da likitanku ba. Kada a taɓa ɗaukar opioid don amfani da wanin wanda aka wajabta shi .
Shin Nucynta daidai yake da tramadol?
Nucynta ya fi karfin tramadol kuma yana da saurin haɗari — Nucynta magani ne na Jadawalin II, yayin da tramadol kuma shi ne na duan lokaci na IV. Nucynta shima ya fi tramadol tsada, wanda ake sameshi da kayan sawa (Ultram). Magunguna da yawa suna ganin cewa tramadol ya isa ya magance ciwo.
Shin Nucynta na haifar da raunin kiba?
Kasa da 1% na marasa lafiya a cikin Nucynta ER Phase 2 da 3 gwaji na asibiti suna da rage nauyi amma ba a bayar da rahoton yawan asarar nauyi ba.
