Main >> Bayanin Magunguna >> Proton pam hanawa (PPIs): Amfani, samfuran yau da kullun, da bayanin aminci

Proton pam hanawa (PPIs): Amfani, samfuran yau da kullun, da bayanin aminci

Maganin Bayanin Maganin Proton famfo masu iyakance ɓoye sinadarin acid a jiki. Ana amfani dasu galibi don magance zafin ciki, rashin narkewar abinci, da GERD.

Idan kun taba jin wani zafi mai zafi wanda ke tashi daga kirjin ku bayan cin abinci, mai yiwuwa kun sami reflux na gastroesophageal (GER), wanda aka fi sani da reflux acid. Sauran cututtukan da wataƙila ka taɓa ji su ne sake yin amfani da abubuwan da ke cikin acid a cikin bakin ko maƙogwaro, tashin zuciya, ciwon makogwaro, kumburin fuska, da haɓaka yawan ruwan miyau. GER yana faruwa sau ɗaya a wani lokaci lokacin da kayan cikinku ya koma cikin hancin ku. Koyaya, idan wannan rashin jin daɗin ya faru akai-akai, to kuna iya samun cututtukan ciki na gastroesophageal ( GERD ), wanda ake bi da shi ta hanyoyi daban-daban.

Yawancin lokaci, likitanku zai fara ba da shawarar wasu canje-canje na rayuwa don inganta alamunku. Idan waɗannan ba su aiki ba, mai ba da sabis naka na iya ba da shawarar mai hana siginar proton (PPI). Akwai PPI daban-daban guda shida, duk suna da tasiri iri ɗaya, don haka idan baku amsa da kyau ba ga ɗaya, kuna da wasu zaɓuɓɓuka da yawa don gwadawa. Ci gaba da karatu don ƙarin koyo game da nau'ikan masu hana fitowar proton a kasuwa, amfanin su, sunayen alamun, da kuma bayanan aminci.

Jerin masu hana ruwa gudu
Sunan suna (suna na gama gari)	Matsakaicin farashin tsabar kudi	SingleCare tanadi	Learnara koyo
Kyauta (omeprazole) *	$ 338.83 a kowace 30, 20 mg capsules	Samu takardun shaida na Prilosec	Bayanin Prilosec
Nexium (esomeprazole) *	$ 275.09 a kowace 30, 40 mg capsules	Samu takardun shaida Nexium	Nexium cikakkun bayanai
Prevacid, SOLUTAB Gabatarwa (lansoprazole) *	$ 189.99 a cikin 30, 30 mg capsules	Samun takardun shaida na Prevacid	Bayanin farko
Dexilant (dexlansoprazole)	$ 491.08 don 30, 30 mg capsules	Samo takardun shaida na Dexilant	Bayanai cikakke
Protonix (pantoprazole)	$ 644.48 a cikin 30, 40 MG Allunan	Samu takardun shaida na Protonix	Bayanin Protonix
Aciphex, Aciphex Yayyafa (rabeprazole)	$ 323.99 don 30, 20 MG allunan	Samo takardun shaida rabeprazole	Bayanin Rabeprazole
Zegerid (omeprazole + sodium bicarbonate) *	$ 3146.09 don 30, 20-1100 mg kawunsa	Samu takardun shaida na Zegerid	Bayanin Zegerid

* akwai a takardar sayan magani da kuma tsarin OTC

Menene proton famfo masu hanawa?

Proton pump inhibitors sune mashahuran magunguna waɗanda akafi amfani dasu don magance GERD da rikice-rikicen ta, kamar su tsauraran peptic da kuma cutar Barrett. Ana amfani da PPIs don magance cututtukan ulcer kamar su Helicobacter pylori (H. pylori) cututtuka da ulce wanda ƙwayoyin cututtukan cututtukan ƙwayoyin cuta (NSAIDs) ke haifarwa. Hakanan ana amfani da wannan rukunin magungunan don sarrafa haɓakar acid mai nauyi a cikin wasu nau'ikan ciwukan ciki. Wasu PPIs ana iya samun su a kan-kanti, yayin da wasu ke buƙatar takardar sayan magani. Ba tare da la'akari ba, masu amfani da proton pump suna amfani da magungunan yadu don yanayin da ke da alaƙa da acid. A zahiri, saboda yalwa da fa'idar su, masu hana ruwa gudu na proton ana yawan amfani dasu tsawon lokaci fiye da yadda ake ba su magani. Don tabbatar da cewa kana shan magungunan ka na tsawon lokaci, ka tabbata ka tattauna wannan tare da likitan ka ko likitan ka.

Ta yaya proton pump inhibitors ke aiki?

Proton pump inhibitors suna aiki ta hanyar ɗaurewa da kuma hana H + / K + -ATPase, wanda shine famfo wanda ke da alhakin ɓoye acid a cikin ciki. Saboda yanayi kamar GERD da ulcers ulcer suna taɓarɓarewa ta cikin ruwan ciki, hana yawan ɓoyewar sinadarin acid a jikinka ba kawai yana magance ƙwannafi, rashin narkewar abinci, da ciwon ciki da ke tattare da GERD ba, amma kuma zai iya taimakawa warkar da murfin jijiyar idan an shafa ta hanyar yashewar acid.

Sauye-sauyen salon rayuwa kamar rage nauyi (idan ka yi kiba ko kuma ka kara nauyi a baya-bayan nan), daukaka kan gado, kaurace wa abinci mai kitse tsakanin awanni 2-3 na yin bacci, da nisantar abinci da abin sha masu sinadarai duk suna taimakawa wajen rage GERD. Mai ba ku sabis na iya ba da shawarar maganin kashe kuɗaɗe ko wani rukunin magunguna da ake kira H2-blockers don taimaka wa GERD ɗin ku.

Me ake amfani da masu hana ruwa gudu na proton?

Manuniya sun dogara da takamaiman magani. Misalan sun hada da:

Bwannafi
GERD
Dyspepsia (rashin narkewar abinci)
Magunguna masu saurin kumburi da marasa narkewa
H.Pylori- hade da ulcers
NSAID hade da ulcers
Ciwon ciki da ciwon duodenal
Rigakafin rebleeding na ulcer
Rashin ciwon ulcer
Rigakafin zubar jini mai larura
Gastrinomas
Ciwon Zollinger-Ellison

Wanene zai iya ɗaukar masu hana motsa jiki?

Manya

Proton pump hanawa gabaɗaya suna da aminci sosai kuma suna da tasiri a cikin manya maza da mata. Duk da yake akwai wasu cutarwa da faɗakarwa ga wannan rukunin magungunan, ta amfani da mafi ƙanƙanci na dole kuma ba ƙetare shawarar da aka ba da shawarar na yawancin lokaci yana haifar da ƙananan ƙarancin sakamako mai tsanani.

Yara da Yara

An yarda da masu hana ruwa na Proton don amfani da su a cikin yara sama da shekara 1 kuma ana ɗora su bisa nauyi. Amfani da PPIs a cikin yara na iya haifar da haɗarin kamuwa da cututtuka kamar ciwon huhu da ciwon ciki wanda kwayar ta haifar Yana da wuya . Proton pump inhibitors na iya ƙara haɗarin karaya a yara. Sabili da haka, waɗannan magungunan ba koyaushe ake ba yara ba har sai sun fara tuntuɓar mai ba da lafiya. Yaran da ke dauke da alamun cutar GERD na iya yin umarnin dakatarwar PPI mai haɗuwa. Koyaya, saboda amfani da proton pump inhibitor a cikin jarirai ba shi da izinin Hukumar Abinci da Magunguna ta Amurka (FDA), yana da damar mai bayarwa na kiwon lafiya ya yanke shawarar buƙata.

Tsofaffi

Saboda amfani na PPI na dogon lokaci na iya ƙara haɗarin kamuwa da C. mai wahala, ƙashin ƙashi, da karaya, ba a ba da shawarar yin amfani da su na tsawan lokaci a cikin tsofaffi ba. A zahiri, da Jerin giya na magungunan da basu dace ba ga tsofaffi sun bada shawarar kada a wuce makonni takwas na ci gaba da amfani da manya a cikin shekaru 65.

Shin masu hana ruwa gudu suna kare lafiya?

Tunowa Masu hanawa na Proton Pump

Auromedics Pharma LLC: Tunawa da son rai na 40top na pantoprazole don Allura saboda kasancewar gilashin gilashi a cikin kwalbar , Disamba 2017

Proton famfo mai hana hanawa

Kada ku ɗauki masu hana motsa jiki idan kuna da tarihin rashin kuzari game da duk wani mai hana ruwa na proton.

Sai dai don esomeprazole , ya kamata a guji masu hana ruwa gudu na proton a cikin marasa lafiya wadanda suma suke shan kayayyakin da ke dauke da sinadarin rilpivirine.

Sauran gargaɗin sun haɗa da:

Saboda maye gurbin acid na proton pump inhibitors, rebound acidity na iya faruwa bayan tsayar da ɗayan waɗannan magunguna kwatsam. Idan kuna ƙoƙarin dakatar da PPI ɗinku, ana ba da shawarar a hankali ku ɗan rage kwayar, koda bayan ɗan gajeren lokacin jiyya na makonni 8.
A cikin al'amuran da ba safai ba, an lura da cututtukan koda da ke juyawa ga marasa lafiya da ke shan PPIs. Wannan ana kiransa tubulointerstitial nephritis kuma yawanci ana gabatar dashi tare da alamun cututtuka wanda ya samo asali daga rashin lafiyan abu (zazzabi, kurji, gajeren numfashi) zuwa ƙarin halayen koda na musamman (anorexia, malaise, tashin zuciya) Idan waɗannan alamun sun faru, ya kamata a dakatar da mai hana siginar kuma a nemi taimakon likita nan da nan.
Amfani na dogon lokaci (shekaru 2 ko sama da haka) na iya haifar da rage shan bitamin B12 kuma ƙarshe, rashi B12. Tunda B12 yana da mahimmin bitamin ga jiki, yana da mahimmanci a saka idanu akan matakan ko kari wannan bitamin idan kuna shan kwayar maganin proton wanda ya wuce shekaru biyu.
Gastric acid na iya zama mai wahala idan ba'a kebe shi da ciki ba. Koyaya, a cikin ciki, wannan acidity yana da mahimmanci don kiyaye matakan ƙwayoyin cuta masu kyau da marasa kyau cikin dubawa. Saboda masu hana ruwa gudu na proton suna hana acidity na ciki, amfani da tsawan lokaci na iya haifar da yawaitar miyagun kwayoyin cuta, watau C. mai wahala. C.Gamewar cuta cuta ce wacce ke haifar da gudawa mai tsanani, rashin ruwa a jiki, da mawuyacin rikitarwa idan ba a magance su ba. Sabili da haka, ya fi dacewa a yi amfani da kaso mafi ƙaranci da mafi ƙanƙan lokaci na maganin hana amfani na proton pump, musamman a cikin tsofaffi masu saukin kamuwa.
An nuna amfani na dogon lokaci na masu hana yaduwar kwayar proton don kara kasadar kasusuwa da raunin kashi. Idan kun kasance a kan babban magani ko maganin PPI na dogon lokaci, ya kamata a kula da ku akai-akai don lafiyar ƙashi. Wasu masu ba da sabis na iya ƙarfafa ƙarfafawa tare da alli ko bitamin D yayin ɗauka mai hana amfani da fanfo.
Ba da daɗewa ba, yin amfani da mai hana ruwa na proton fiye da watanni uku ya haifar da raguwar matakan magnesium. Mafi munin lokuta na iya haɗawa da kamuwa ko jin bugun zuciya mara tsari. Idan kuma kuna shan diuretic, digoxin, ko wani magani wanda zai iya haifar da hypomagnesemia, mai ba ku sabis na iya ɗaukar karatun farko na matakan magnesium don kiyayewa.
Wani mawuyacin tasirin da ke tattare da amfani da mai hana amfani na proton na dogon lokaci shine cutar rashin kuzari da ake kira lupus. Gabaɗaya, idan lupus ya faru yayin amfani da PPI, yana nuna kamar rashes ko raunuka akan yankuna na fata waɗanda suka karɓi rana mafi yawa kuma ana kiranta lupus cutaneous. Wani lokaci ana iya samun dauki wanda ya shafi dukkan jiki, wanda ke gabatar da ciwon haɗin gwiwa, rashes, gajiya mai tsanani, da ƙananan zazzaɓi. Yanayin jiki, da ake kira lupus systemic, na iya faruwa tsakanin justan kwanaki kaɗan na amfani da mai hana ruwa na proton. Abin farin, lupus wanda ke haifar da amfani da proton pump inhibitor yawanci yakan warware tsakanin watanni 1-3 na dakatar da shan magani.
Proton pump inhibitors na iya rage tasirin clopidogrel, magani da ake amfani da shi don hana daskarewar jini. Wannan yana faruwa ne saboda PPIs suna hana enzyme da ake kira CYP2C19, wanda ke da mahimmanci don canza clopidogrel zuwa yanayin aikin sa. Saboda wannan haɗin hulɗar miyagun ƙwayoyi, ya zama dole a sanar da likitanka kafin fara PPI idan kun riga kuna shan clopidogrel ko akasin haka.

Shin zaku iya shan masu hana ruwa gudu a lokacinda suke ciki ko masu shayarwa?

Mata masu ciki yakamata su fara yunƙurin canje-canje na rayuwa don magance GERD kuma suyi shawara da likitocin su kafin ɗaukar PPI. Saboda ƙananan ƙwayoyi na waɗannan ƙwayoyi na iya wucewa cikin nono, ya kamata mata masu shayarwa su yi magana da masu ba da kiwon lafiya kafin amfani da mai hana ruwa na proton.

Shin proton pump inhibitors sune abubuwan sarrafawa?

A'a, proton pump inhibitors ba abubuwa ne masu sarrafawa ba.

Magungunan proton famfo na yau da kullun masu illa

Proton pam hanawa gabaɗaya suna da juriya sosai. Koyaya, akwai wasu illoli na yau da kullun waɗanda zasu iya faruwa, kamar ciwon kai, maƙarƙashiya, gudawa, da kuma damuwa da ciki.

Arin cututtukan haɗari masu tsanani waɗanda ke buƙatar kulawa da gaggawa kai tsaye kamar haka:

Alamomin rashin lafiyan (kurji, amya, wahalar numfashi ko haɗiyewa, ko kumburin leɓɓa, makogwaro, ko baki)
Alamomin ƙananan matakan magnesium (canjin yanayi, ciwon tsoka ko rauni, raɗaɗi, rawan jiki, kamuwa, bugun zuciya mara kyau)
Canje-canje a cikin aikin koda (rashin samun damar yin fitsari, jini a cikin fitsari, ko samun karin nauyi nan da nan)
Dizziness ko wucewa
Jin ƙyama ko ƙwanƙwasa a hannu da ƙafa
Ciwon ƙashi
Ciwon ciki, kujerun mara sako-sako, gudawa
Matsalar fata mai tsanani na iya faruwa wanda ake kira ciwo na Stevens-Johnson. Kodayake ba safai bane, yana da matukar tasiri. Nemi taimakon gaggawa idan kun sami ja, kumbura, kunbura, ko ɓarke fata, ko ciwo a bakin, maƙogwaro, hanci, ko idanunku.

Nawa ne kudin masu hana ruwa gudu na proton?

Ana samun masu hanawa na Proton pump a cikin OTC da kuma takardar magani. Sigogin OTC kamar su esomeprazole kuma lansoprazole yawanci kudin bai wuce $ 30 a kantin magani na gida ba. Takaddun maganin proton pump masu hana shi sun kasance mafi tsada a cikin farashi, suna yin sama da $ 100 don wadatar wata ɗaya idan basu da inshora. Misali, omeprazole shine PPI na farko da aka gabatar dashi zuwa kasuwa, amma har yanzu matsakaita ya wuce $ 50 a wata ba tare da inshora ba. A coupon daga SingleCare na iya rage farashin omeprazole don ka biya ƙasa da $ 10 a kantin magunguna da ke halartar. Inshorar ku na iya samun fifiko akan wacce masu hana ruwa gudu na kwayoyi za su rufe, don haka idan abin da kuka zaba ba ya kan tsarin, koyaushe ku duba tare da SingleCare don tabbatar da cewa kuna biyan mafi kyawun farashin.