Humira sakamako masu illa da yadda za'a guje su

Bayanin Magunguna

Humira sakamako masu illa | Har yaushe tasirin sakamako zai wuce? | Gargadi | Abubuwan hulɗa | Yadda ake kauce wa illoli

Humira (adalimumab) - allura ce ta wani abu da ke faruwa ga mutum - yana haifar da gafartawa kuma yana sarrafa alamomin cututtukan cututtukan zuciya. Mai ba da sabis na kiwon lafiya na iya tsara Humira don rheumatoid amosanin gabbai , ankylosing spondylitis, cututtukan yara na idiopathic , amosanin gabbai, plaque psoriasis , Cutar Crohn , ulcerative colitis, uveitis, da hidradenitis suppurativa. A duk waɗannan yanayin, saurin tashi yakan faru ne lokacin da tsarin garkuwar jiki yayi kuskuren kai hari ga ƙwayoyin lafiya.

Humira tana danne amsawar garkuwar jiki ta hanyar toshe wani sinadari da jiki ke samarwa-tumo necrosis factor ko TNF-wanda ke haifar da kumburi. Kamar kowane magani, yanke shawarar shan Humira dole ne ya daidaita fa'idodi da haɗarin maganin, don haka yana da mahimmanci ku tattauna tare da likitanku game da illolin, hulɗar magunguna, da gargaɗin da ke tattare da maganin.

Dangantaka: Learnara koyo game da Humira | Samu rangwamen Humira

Sakamakon illa na yau da kullun na Humira

Humira tana dankwafar da garkuwar jiki, saboda haka cutuka da cututtukan cuta na gama gari ne da kuma illa masu illa. Hakanan, a matsayin allurar subcutaneous, Humira tana samar da halayen shafin allura cikin kusan 1 cikin 5 marasa lafiya . Abubuwan da yafi illa ga Humira sune:

• Hanyoyin yanar gizo na allura (redness, kumburi, zafi, ƙaiƙayi, da kumburin fata)
• Babban cututtuka na numfashi
• Cunkoson Sinus
• Ciwon kai
• Developmentaddamar da ƙwayoyin cuta
• Rash
• Ciwan
• Ciwon ciki
• Ayyukan hanta mara kyau
• Cutar fitsari
• Mura ko alamun sanyi
• Ciwon baya
• Levelsara yawan matakan mai a cikin jini
• Maɗaukakin ƙwayar cholesterol
• Hawan jini

Shin Humira tana haifar da zubewar gashi ko karin kiba?

A cikin al'amuran da ba safai ba, Humira na iya haifar da asarar gashi.

Rage nauyi ko nauyi mai nauyi da ba a fayyace shi ba, ko da yake, Humira ba ya haifar da shi kai tsaye. Koyaya, sinadarin da yake aiki yana ƙara haɗarin cutar lymphoma, cutar sankarar bargo, da sauran cututtukan daji, yawancin su ana alakanta su da rashin cin abinci da kuma rage nauyi mara nauyi. Yi magana da likita nan da nan idan ka lura da raunin nauyi, rage ƙoshin abinci, ko cikawa a ɗan ƙaramin abinci yayin shan Humira.

Humira mai tsanani

Saboda Humira tana dakile garkuwar jiki, marasa lafiya suna cikin haɗarin kamuwa da cuta mai tsanani har ma da barazanar rai da cutar kansa. Kamar yadda yake tare da alluran allurar riga-kafi, halayen rashin lafiyan ma haɗari ne. Illolin Humira mafi tsanani sune

• M cututtuka ko barazanar rai
• Ciwon daji (lymphoma, leukemia, non-melanoma ciwon daji na fata, da sauran cututtukan cuta)
• Matsanancin rashin lafia ko barazanar rai
• Ciwon tarin fuka ko cutar hepatitis B
• Acerarfafawa ko farawa na rikice-rikicen tsarin juyayi kamar su sclerosis da yawa ko neuritis na gani
• Matsalar zuciya (atrial fibrillation, tachycardia, cardiac arrhythmia, ciwon kirji, ciwon zuciya)
• Mummunan ciwan zuciya
• Ciwon Lupus-like
• Cellididdigar ƙwayar ƙwayar jini ko ƙarancin jini
• Lalacewar hanta ko gazawa
• Duwatsu masu tsakuwa
• Ciwon ido
• Amosanin gabbai
• Raunin jijiyoyi
• Rikicewa

Ya kamata ku daina shan Humira kuma ku nemi likita nan da nan idan kun sami ɗayan ɗayan halayen halayen nan masu zuwa yayin shan Humira:

• Zazzaɓi, gajiya, rashin cin abinci, ciwon ciki, ko waninsu alamun kamuwa da cutar hepatitis B .
• Kumburin kumburi, gajiya, zazzabi, sanyi, zufa da dare, rashin ci, rage nauyi mara nauyi, kumburin fata da ba a bayyana ba, saurin rauni ko zubar jini, ko wasu alamomin cutar kansa .
• Hawan ciki, kumburin fuska, furewa, fata mai laushi, matsalar numfashi, sauke saukar karfin jini, jiri, suma, ko wasu alamun rashin lafiya mai tsanani ko anaphylaxis .
• Gajiya, zazzaɓi, ciwon gaɓoɓi, zafin fuska, raunin hasken rana da ke haifar da cututtukan fata, ƙarancin numfashi, da sauransu alamun cututtukan lupus-like .
• Racing bugun zuciya, bugun zuciya, ciwon kirji, ko wasu alamun rashin daidaituwar zuciya .

Ana iya dakatar da allurar Humira idan ɗayan waɗannan halaye sun sami kwarewa.

Ya kamata kai tsaye ka yi magana da likitanka game da yiwuwar dakatar da Humira idan ka fuskanci:

• Zazzaɓi, tari, kumburi, sanyi, sanyi, ƙwanƙwasa, rashin cin abinci, ciwon ciki, ko waninsu alamun kamuwa da cuta .
• Rauni, gajiya, kodadde fata, bugun zuciya mai sauri, saurin rauni ko zubar jini, ko wasu alamun matsalolin jini .
• Fata mai launin rawaya, idanun rawaya, gefen dama na gefen ciki, kumburin ciki, rikicewa, da sauran su alamun manyan matsalolin hanta .
• Raunin jijiyoyi, sauyin hangen nesa, taurin tsoka, jijiyoyin tsoka, tingling, numbness, ko wasu alamun rikicewar tsarin .

Ana amfani da Humira sau ɗaya kawai a kowane mako biyu, don haka likitoci da marasa lafiya suna da lokacin da za su sake tunani game da Humira ta fuskar illa mara kyau.

Yaya tsawon lokacin sakamako Humira yake wucewa?

Humira sakamako masu illa zai bambanta a farawa da tsawon lokaci. Shafin allura ko halayen rashin lafiyan galibi suna faruwa ne tsakanin minutesan mintina na allurar kuma ya wuce minutesan mintuna zuwa fewan kwanaki. Allurar farko zata kasance koyaushe daga ƙwararrun likitocin kiwon lafiya a cikin tsarin asibiti don saka idanu kan yiwuwar halayen rashin lafiyan. Sauran cututtukan da ake samu na yau da kullun kamar ciwon kai, cunkoson sinus, tashin zuciya, da mura ko alamomin sanyi suma a takaice suke kuma ana iya magance su tare da magunguna da kuma hutawa.

Koyaya, cututtukan da suka fi tsanani, kamar matsalolin hanta, cututtuka, da matsalolin jini zasu ɗauki makonni ko watanni don haɓakawa kuma na iya ci gaba da zama mafi muni muddin aka ɗauki Humira. Cututtuka masu tsanani, kansar, gazawar hanta, matsalolin zuciya, da kwayar cutar ta atomatik na iya samun sakamako na dogon lokaci ko na tsawon rai koda bayan an dakatar da Humira. Ziyartar ofishi akai-akai da gwaje-gwaje wajibi ne don lura da tasirin Humira na dogon lokaci.

Humira sabawa & gargadi

Humira ba koyaushe shine madaidaicin magani ga kowa ba. Mutanen da ke da cututtuka, cututtukan ɓoye, kamuwa da cutar tarin fuka, tarihin cutar kansa, cututtukan zuciya, rikicewar jijiyoyi irin su sclerosis da yawa, cututtukan hanta, ko ƙoshin lafiya ga magani ko kowane kayan aikinta bazai dace da candidatesan takarar Humira ba.

Cututtuka masu tsanani

Humira ta ƙunshi gargaɗin akwatin baƙar fata don munanan cututtuka. Za a dakatar da Humira idan mummunar cuta, sepsis, ko kamuwa da cutar fungal ta ɓarna yayin shan magani.

Marasa lafiya za su buƙaci a gwada su ga tarin fuka kafin da kuma yayin jiyya da Humira. Duk wani mai haƙuri da ya gwada tabbatacce ga cutar tarin fuka a ɓoye zai bukaci maganin tarin fuka kafin karɓar Humira. Za a dakatar da maganin idan mai haƙuri ya kamu da cutar tarin fuka yayin jiyya.

Za a kuma gwada marasa lafiyar da ke cikin haɗarin ciwon hanta na B ko kuma cututtukan histoplasmosis kafin su karɓi Humira. Bugu da ƙari, za a dakatar da maganin idan allurar ta sake kunna kamuwa da cutar hepatitis B a ɓoye.

Rashin lafiya

Humira da sauran masu toshe TNF suna ƙunshe da gargaɗin akwatin baƙar fata don cutarwar cuta, musamman lymphoma. Wasu marasa lafiya a kan Humira da sauran masu toshe TNF sun ɓullo da kwayar cutar T-cell lymphoma (HSTCL), mai saurin tashin hankali, wacce ba kasafai ake samun ta ba, kuma galibi irin cutar ta lymphoma ce. Marasa lafiya waɗanda aka ba da magani ga kowane ciwon daji ban da cutar kansa na melanoma na fata ba zai dace da 'yan takarar neman magani tare da Humira ko masu kama TNF ba. Idan mummunan cuta ya ɓullo a yayin jiyya, ana iya dakatar da Humira.

Disorderswayoyin cuta

Marasa lafiya da ke fama da cutar rashin ƙarfi irin su sclerosis da yawa, cututtukan Guillain-Barre, cututtukan da ke tattare da lalata jikin mutum, ko kuma neuritis na ƙila ba za su iya zama 'yan takarar da suka dace don maganin Humira ba. Cututtukan da ke lalata mutane sune cututtukan jijiyoyi masu ci gaba waɗanda a hankali suke cire ƙarancin kariya a kusa da rassan jijiya, yana rage ikonsu na wuce siginar jijiyoyin. Humira na iya haifar da tashin hankali na ɗayan waɗannan rikice-rikice, don haka maganin Humira zai buƙaci saka idanu akai-akai a cikin waɗannan marasa lafiya.

Ciwon zuciya mai narkewa

Humira na iya kara lalacewar zuciya, don haka marasa lafiya da ke fama da ciwon zuciya za su buƙaci a sanya musu ido sosai lokacin shan Humira.

Allerji

Marasa lafiya da ke da rashin lafiyan magani, duk wani kayan aikinta, ko roba da latex bazai dace da candidatesan takarar Humira ba. Za a dakatar da miyagun ƙwayoyi a kowane alamar rashin lafiyan rashin lafiya mai tsanani.

Ciki

Bayanai na asibiti ya nuna cewa haɗarin dangin manyan lahani na haihuwa bai fi na matan da aka kula da su da Humira akan waɗanda ba haka ba. A matsayinta na furotin, Humira ta ratsa mahaifa zuwa tayi. Antian rigakafi ne ke shiga cikin tayi a farkon watannin farko, amma wucewar ƙwayoyin cuta a hankali yana ƙaruwa har sai ya yi girma a cikin watanni uku na uku. Mata masu ciki za su iya so su tattauna da likitocinsu haɗari da fa'idar shan Humira yayin da suke da ciki.

Shan nono

Ana daukar Humira amintacciya a sha yayin shayar da jarirai. Humira bai bayyana yana shafar samar da madara ba ko cutar da jarirai masu shayarwa. Humira tana cikin madarar nono amma a cikin kashi ɗaya ko ofasa na mai da hankali a cikin jini. Hakanan furotin ne, don haka za'a lalata shi a tsarin narkewar jarirai.

Zagi da dogaro

Humira ba ta samar da dogaro da jiki ko alamun bayyanar cututtuka ba. Babu sanannun shari'un Humira ko wani cin zarafin TNF.

Humira hulɗa

Bai kamata a yi amfani da wasu magungunan ƙwayoyin cuta masu hana ilimin halittar jiki tare da Humira ba saboda, a haɗe da Humira, waɗannan magungunan suna cutar da garkuwar jiki cikin haɗari. Ba za a sanya Humira a hade tare da masu rigakafi masu zuwa ba:

• Orencia (abatacept)
• Kineret (anakinra)
• Remicade (infliximab)
• Enbrel (ƙari)
• Cimzia (certolizumab pegol)
• Simponi (golimumab)

Humira na iya haɓaka tasirin wasu magungunan rigakafi ko inganta garkuwar jiki, yana ƙara haɗarin kamuwa da cutar kansa. Wani likita zai yi taka tsantsan yayin rubuta Humira tare da:

• Imuran (azathioprine)
• Purinethol (6-kayan kwalliya)
• Cladribine
• Rituxan (rituximab)
• Xgeva (denosumab)
• Ocrevus (yawanciniya)
• Actemra (tocilizumab)
• Gilenya (fingolimod)
• Mayzent (siponimod)
• Daliresp (roflumilast)

Humira yana ƙara yawan guba kuma yana kara tasirin tasirin wasu magunguna, gami da waɗannan masu zuwa:

• Arava (larfomunomide)
• Ilaris (canakinumab)
• Tysabri (natalizumab)
• Entyvio (vedolizumab)
• Shirye-shirye (tacrolimus)
• Elidel (pimecrolimus)
• Arcalyst (rilonacept)

Humira yana rage tasirin maganin wasu magunguna kamar warfarin, alurar riga kafi, da echinacea. Kodayake babu hatsari, ƙungiyar masu kiwon lafiya na iya buƙatar gyara waɗannan takaddun ko maganin su.

Maƙerin Humira bai nuna cewa ya kamata a guji shan giya ba. Zai yuwu, to, shan giya daidai gwargwado yayin shan Humira yana da aminci. Wannan na iya zama gaskiya, duk da haka, ga marasa lafiya masu fama da matsalar hanta. Humira na iya haifar da matsalolin hanta kuma - a cikin mawuyacin yanayi - gazawar hanta, don haka tuntuɓi likita game da shan giya yayin shan Humira.

Yadda ake kauce ma illar Humira

Yawancin kwayoyi suna haifar da sakamako masu illa, don haka babu tabbatacciyar hanyar da za a iya kauce wa illa yayin shan magunguna. Koyaya, zaku iya rage haɗari da tsananin tasirin illa tare da withan nasihu.

1. Ka gaya wa likitanka duk yanayin lafiyar ka da magungunan ka

Saboda haɗarin mummunar illa, ya kamata ka gaya wa likitanka game da:

• Cututtuka masu aiki ko na baya (musamman hepatitis B ko tarin fuka)
• Tarihin cutar kansa, cututtukan tsarin juyayi (kamar su sclerosis da yawa ko ciwon Guillain-Barre), ko gazawar zuciya
• Idan kana da juna biyu ko kuma shayarwa
• Duk wani magunguna ko kayan abincin da zaka iya sha, gami da magunguna marasa magani
• Alurar riga kafi ta kwanan nan ko mai zuwa
• Umbanƙara, ƙwanƙwasawa, matsalolin gani, ko raunin tsoka
• Ruwan roba ko na latti

Lokacin shan Humira, sanar da likitanka nan da nan idan ka yi rashin lafiya ko ka yi ciki. Kada ku fara shan kowane magani ko ƙarin abincin har sai kun fara magana da likitanku.

2. Kiyaye duk alƙawarin likita

Za a kula da marasa lafiya a kan Humira don hana mummunan sakamako. Wannan zai buƙaci gwajin jini na yau da kullun da kuma ziyarar ofis don kama matsaloli kafin su haɓaka cikin manyan matsalolin likita.

3. Guji cututtuka

Humira ta sa marasa lafiya zama masu saukin kamuwa da cututtuka. Don kiyaye kanka da aminci, gudanar da ayyukkan nisantar da jama'a, sanya abin rufe fuska a bainar jama'a, guje wa mutane masu kamuwa da cututtuka, wanke hannuwanku a kai a kai, yin wanka a kai a kai, da ɗauke da amfani da sabulun hannu a kai a kai

4. Guji allurar riga-kafi kai tsaye

Kuna iya karɓar rigakafin yayin shan Humira matuƙar ba alurar riga kafi ba ce. Lokacin da aka ba marasa lafiya marasa lafiya, maganin rigakafin rayuwa ba kawai yana da haɗarin haifar da kamuwa da cuta ba, kamuwa da cuta na iya yaduwa cikin ilahirin jiki. Yi magana da mai ba da lafiya kafin ɗaukar alurar riga kafi yayin shan Humira. Mafi kyawun aiki shine samun cikakkun bayanai kan alluran rigakafin kafin fara Humira ko duk wani maganin da ke hana garkuwar jiki. Lokacin da aka dakatar da Humira, jira aƙalla watanni biyu kafin a sami rigakafin kai tsaye.

5. Ajiye duk magungunan ka

Don rage haɗarin illa da hulɗar miyagun ƙwayoyi da haɗari masu haɗari, yana da kyau koyaushe adana jerin duk magungunan ku sabunta kowane lokaci. Anyara da kowane irin magunguna da magunguna, bitamin, da kuma abubuwan ganye waɗanda kuke sha a kai a kai. Koyaushe nuna wannan jerin lokacin ganin likitanka ko lokacin cika takardar sayan magani.

6. A kai a kai canza wurin allurar

Mafi yawan illolin Humira sune halayen shafin allura. Hanya mafi sauki don sarrafa tasirin shafin allura shine canza wurin allurar tare da kowane allura. Ana yi wa Humira allura sosai sau ɗaya kowane mako biyu a cikin ciki ko cinya, don haka yi la'akari da juyawar allurar tsakanin kowane cinya da ciki. Guji ba da allurar cikin fata mai laushi, mai laushi, ja, kumbura, rauni, ko ƙaiƙayi.

Hakanan kuna iya rage halayen gidan yanar gizo ta allurar cire allurar riga-kafi ko allurar alkalami daga firiji kafin allurar. Humira na iya kasancewa a cikin yanayin yanayin ɗaki na tsawon mintuna 30 kafin allurar. Tabbatar, duk da haka, ba a fallasa shi zuwa hasken rana ba. Kada kuyi ƙoƙarin dumama magani ta wata hanyar.

7. Tambayi likitanka game da Humira mara citta

Citric acid wani abin adanawa ne wanda ke taimakawa wajen kiyaye magungunan allura-musamman sunadarai irin su Humira-barga cikin watanni da yawa na ajiya. Buffers na citrate, duk da haka, galibi suna haifar da babban ciwo na minutesan mintoci bayan allurar. Idan ciwon allurar Humira ya yi yawa da za a ɗauka, tambayi likitanka game da Humira marar kyauta a madadin.

Abubuwan da ke da alaƙa da tasirin Humira:

• Adalimumab , StatPearls
• Masu gyaran ilimin halittu , StatPearls
• Karya tsohon halaye: ƙaurace wa buffers da aka saba amfani da su a cikin magunguna , Nazarin Magungunan Turai
• Humira , Munafunci
• Humira ga kwararrun likitocin kiwon lafiya , AbbVie
• Humira jagorar magani , AbbVie
• Humira tana tsara bayanai , AbbVie
• Tumor necrosis factor masu hanawa , StatPearls
• Masu hana ƙwayoyin cuta necrosis factor: a primer na asibiti , Gudanar da Raunin Lafiya